Q9ZV65

PR
Gene name
HDG3
Protein name
Homeobox-leucine zipper protein HDG3
Names
HD-ZIP protein HDG3, Homeodomain GLABRA 2-like protein 3, Homeodomain transcription factor HDG3, Protein HOMEODOMAIN GLABROUS 3, Protein UPCURVED LEAF 1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G32370
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-94 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9ZV65

Entry ID Method Resolution Chain Position Source
AF-Q9ZV65-F1 Predicted AlphaFoldDB

31 variants for Q9ZV65

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_13742422_C_G 5 N>K No 1000Genomes
ENSVATH01938787 27 N>K No 1000Genomes
tmp_2_13742552_A_T 49 N>Y No 1000Genomes
tmp_2_13742563_T_A 52 S>R No 1000Genomes
ENSVATH01938788 61 N>K No 1000Genomes
ENSVATH01938789 62 N>Y No 1000Genomes
ENSVATH01938800 140 N>K No 1000Genomes
ENSVATH00256871 261 L>F No 1000Genomes
ENSVATH05643504 265 A>T No 1000Genomes
tmp_2_13743946_C_G 279 T>S No 1000Genomes
tmp_2_13743965_G_T 285 L>F No 1000Genomes
tmp_2_13743966_G_T 286 D>Y No 1000Genomes
ENSVATH05643505 289 E>G No 1000Genomes
ENSVATH13505849 291 T>M No 1000Genomes
ENSVATH13505850 298 P>A No 1000Genomes
ENSVATH05643506 305 T>I No 1000Genomes
tmp_2_13744069_G_A 320 G>D No 1000Genomes
ENSVATH05643508 321 I>V No 1000Genomes
ENSVATH14578173 347 Q>E No 1000Genomes
ENSVATH05643517 378 E>Q No 1000Genomes
tmp_2_13744511_G_A 401 D>N No 1000Genomes
ENSVATH05643519 421 Q>E No 1000Genomes
ENSVATH13505853 422 E>D No 1000Genomes
tmp_2_13744726_T_G 439 D>E No 1000Genomes
tmp_2_13744845_C_G 479 T>R No 1000Genomes
tmp_2_13744848_A_T 480 D>V No 1000Genomes
ENSVATH05643521 483 S>P No 1000Genomes
tmp_2_13745346_A_C 590 K>Q No 1000Genomes
ENSVATH01938819 598 I>T No 1000Genomes
ENSVATH13505878 653 D>E No 1000Genomes
tmp_2_13745803_G_A 714 R>Q No 1000Genomes

No associated diseases with Q9ZV65

1 regional properties for Q9ZV65

Type Name Position InterPro Accession
domain Ubiquitin-conjugating enzyme E2 10 - 160 IPR000608

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
lipid binding Binding to a lipid.

2 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
cotyledon development The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O88933 Esx1 Extraembryonic, spermatogenesis, homeobox 1 (Homeobox protein SPX1) (Homeodomain protein EPX) Mus musculus (Mouse) EV
Q8L7H4 HDG4 Homeobox-leucine zipper protein HDG4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSQSNMVPVA NNGDNNNDNE NNNNNNNNGG TDNTNAGNDS GDQDFDSGNT SSGNHGEGLG
70 80 90 100 110 120
NNQAPRHKKK KYNRHTQLQI SEMEAFFREC PHPDDKQRYD LSAQLGLDPV QIKFWFQNKR
130 140 150 160 170 180
TQNKNQQERF ENSELRNLNN HLRSENQRLR EAIHQALCPK CGGQTAIGEM TFEEHHLRIL
190 200 210 220 230 240
NARLTEEIKQ LSVTAEKISR LTGIPVRSHP RVSPPNPPPN FEFGMGSKGN VGNHSRETTG
250 260 270 280 290 300
PADANTKPII MELAFGAMEE LLVMAQVAEP LWMGGFNGTS LALNLDEYEK TFRTGLGPRL
310 320 330 340 350 360
GGFRTEASRE TALVAMCPTG IVEMLMQENL WSTMFAGIVG RARTHEQIMA DAAGNFNGNL
370 380 390 400 410 420
QIMSAEYQVL SPLVTTRESY FVRYCKQQGE GLWAVVDISI DHLLPNINLK CRRRPSGCLI
430 440 450 460 470 480
QEMHSGYSKV TWVEHVEVDD AGSYSIFEKL ICTGQAFAAN RWVGTLVRQC ERISSILSTD
490 500 510 520 530 540
FQSVDSGDHI TLTNHGKMSM LKIAERIART FFAGMTNATG STIFSGVEGE DIRVMTMKSV
550 560 570 580 590 600
NDPGKPPGVI ICAATSFWLP APPNTVFDFL REATHRHNWD VLCNGEMMHK IAEITNGIDK
610 620 630 640 650 660
RNCASLLRHG HTSKSKMMIV QETSTDPTAS FVLYAPVDMT SMDITLHGGG DPDFVVILPS
670 680 690 700 710 720
GFAIFPDGTG KPGGKEGGSL LTISFQMLVE SGPEARLSVS SVATTENLIR TTVRRIKDLF
PCQTA