Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9ZV51

Entry ID Method Resolution Chain Position Source
AF-Q9ZV51-F1 Predicted AlphaFoldDB

23 variants for Q9ZV51

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH13266103 8 R>Q No 1000Genomes
ENSVATH01838951 20 H>P No 1000Genomes
tmp_2_8093661_C_A 65 L>I No 1000Genomes
ENSVATH05526610 67 R>H No 1000Genomes
tmp_2_8093679_C_T 71 R>C No 1000Genomes
tmp_2_8093698_G_A 77 R>Q No 1000Genomes
tmp_2_8093704_A_T 79 E>V No 1000Genomes
tmp_2_8093720_A_T 84 L>F No 1000Genomes
ENSVATH05526612 84 L>S No 1000Genomes
ENSVATH14516790 85 S>P No 1000Genomes
ENSVATH14516791 119 Q>* No 1000Genomes
ENSVATH05526613 136 K>N No 1000Genomes
tmp_2_8093895_C_G 143 L>V No 1000Genomes
ENSVATH05526614 149 P>A No 1000Genomes
ENSVATH13266127 151 C>* No 1000Genomes
ENSVATH13266126 151 C>S No 1000Genomes
tmp_2_8093940_T_A 158 W>R No 1000Genomes
ENSVATH01838953 163 Q>* No 1000Genomes
ENSVATH00237110 166 E>K No 1000Genomes
tmp_2_8093968_T_C 167 L>S No 1000Genomes
tmp_2_8093982_G_C 172 G>R No 1000Genomes
ENSVATH01838954 180 D>H No 1000Genomes
ENSVATH01838954 180 D>N No 1000Genomes

No associated diseases with Q9ZV51

3 regional properties for Q9ZV51

Type Name Position InterPro Accession
domain Protein kinase domain 94 - 354 IPR000719
active_site Serine/threonine-protein kinase, active site 213 - 225 IPR008271
binding_site Protein kinase, ATP binding site 100 - 123 IPR017441

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

2 GO annotations of biological process

Name Definition
cellular response to hypoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VE61 CG7694 E3 ubiquitin-protein ligase RNF181 homolog Drosophila melanogaster (Fruit fly) PR
O00237 RNF103 E3 ubiquitin-protein ligase RNF103 Homo sapiens (Human) PR
Q86Y13 DZIP3 E3 ubiquitin-protein ligase DZIP3 Homo sapiens (Human) PR
Q9Y3E7 CHMP3 Charged multivesicular body protein 3 Homo sapiens (Human) EV
Q9R1W3 Rnf103 E3 ubiquitin-protein ligase RNF103 Mus musculus (Mouse) PR
Q9EPZ8 Rnf103 E3 ubiquitin-protein ligase RNF103 Rattus norvegicus (Rat) PR
Q9SI09 XERICO Probable E3 ubiquitin-protein ligase XERICO Arabidopsis thaliana (Mouse-ear cress) PR
Q9SKK8 ATL22 RING-H2 finger protein ATL22 Arabidopsis thaliana (Mouse-ear cress) PR
P0CH02 ATL21B Putative RING-H2 finger protein ATL21B Arabidopsis thaliana (Mouse-ear cress) PR
P0CH01 ATL21A Putative RING-H2 finger protein ATL21A Arabidopsis thaliana (Mouse-ear cress) PR
O22255 ATL64 RING-H2 finger protein ATL64 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RXX9 ATL6 E3 ubiquitin-protein ligase ATL6 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYT9 SIS3 E3 ubiquitin-protein ligase SIS3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZJ6 ATL5 RING-H2 finger protein ATL5 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXF8 SGR9 E3 ubiquitin-protein ligase SGR9, amyloplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q8LGA5 ATL31 E3 ubiquitin-protein ligase ATL31 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUZ9 ATL63 RING-H2 finger protein ATL63 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPPTNNYRIS GEPPSTTPSH PPPKPKTRIL SLFLVGVIMF SIFFLFLVLI GIASVLILPL
70 80 90 100 110 120
LLSSLHRHHR RRRRNRRQES SDGLSSRFVK KLPQFKFSEP STYTRYESDC VVCFDGFRQG
130 140 150 160 170 180
QWCRNLPGCG HVFHRKCVDT WLLKASTCPI CRARVRLWEE DPQEGELWRC FGHRRSSLLD
L