Q9ZPS3
Gene name |
GAD4 (At2g02010, F14H20.8) |
Protein name |
Glutamate decarboxylase 4 |
Names |
GAD 4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G02010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZPS3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZPS3-F1 | Predicted | AlphaFoldDB |
27 variants for Q9ZPS3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_476473_G_T | 8 | S>Y | No | 1000Genomes | |
| tmp_2_476091_G_C | 73 | D>E | No | 1000Genomes | |
| tmp_2_476054_C_T | 86 | D>N | No | 1000Genomes | |
| tmp_2_475993_C_T | 106 | R>H | No | 1000Genomes | |
| ENSVATH05212322 | 115 | G>S | No | 1000Genomes | |
| ENSVATH05212321 | 138 | K>N | No | 1000Genomes | |
| tmp_2_475850_T_G | 154 | K>Q | No | 1000Genomes | |
| tmp_2_475624_C_T | 196 | V>I | No | 1000Genomes | |
| tmp_2_475616_C_T | 198 | M>I | No | 1000Genomes | |
| tmp_2_475609_C_T | 201 | E>K | No | 1000Genomes | |
| ENSVATH10585927 | 229 | V>I | No | 1000Genomes | |
| tmp_2_475520_C_A | 230 | E>D | No | 1000Genomes | |
| ENSVATH00201424 | 258 | E>D | No | 1000Genomes | |
| tmp_2_475352_C_T | 258 | E>K | No | 1000Genomes | |
| tmp_2_475346_C_T | 260 | E>K | No | 1000Genomes | |
| ENSVATH01610389 | 264 | R>Q | No | 1000Genomes | |
| tmp_2_475249_G_A | 292 | T>I | No | 1000Genomes | |
| tmp_2_475215_A_T | 303 | H>Q | No | 1000Genomes | |
| tmp_2_475195_T_C | 310 | D>G | No | 1000Genomes | |
| tmp_2_474762_T_G | 365 | K>N | No | 1000Genomes | |
| tmp_2_474680_G_C | 393 | H>D | No | 1000Genomes | |
| tmp_2_474678_A_T | 393 | H>Q | No | 1000Genomes | |
| tmp_2_474676_G_A | 394 | T>I | No | 1000Genomes | |
| tmp_2_474674_G_T | 395 | L>I | No | 1000Genomes | |
| tmp_2_474543_C_A | 438 | E>D | No | 1000Genomes | |
| tmp_2_474520_G_A | 446 | T>M | No | 1000Genomes | |
| tmp_2_474487_T_C | 457 | N>S | No | 1000Genomes |
No associated diseases with Q9ZPS3
No regional properties for Q9ZPS3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9ZPS3 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
| glutamate decarboxylase activity | Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamate catabolic process | The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q04792 | GAD1 | Glutamate decarboxylase | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P69908 | gadA | Glutamate decarboxylase alpha | Escherichia coli (strain K12) | PR |
| P69910 | gadB | Glutamate decarboxylase beta | Escherichia coli (strain K12) | EV |
| Q42521 | GAD1 | Glutamate decarboxylase 1 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9LSH2 | GAD5 | Glutamate decarboxylase 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P54767 | Glutamate decarboxylase | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVLSKTVSES | DVSIHSTFAS | RYVRNSLPRF | EMPENSIPKE | AAYQIINDEL | MLDGNPRLNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASFVTTWMEP | ECDKLMMESI | NKNYVDMDEY | PVTTELQNRC | VNMIARLFNA | PLGDGEAAVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VGTVGSSEAI | MLAGLAFKRQ | WQNKRKAQGL | PYDKPNIVTG | ANVQVCWEKF | ARYFEVELKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VNLREDYYVM | DPVKAVEMVD | ENTICVAAIL | GSTLTGEFED | VKLLNDLLVE | KNKQTGWDTP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IHVDAASGGF | IAPFLYPELE | WDFRLPLVKS | INVSGHKYGL | VYAGIGWVVW | RTKTDLPDEL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFHINYLGAD | QPTFTLNFSK | GSSQVIAQYY | QLIRLGFEGY | RNVMDNCREN | MMVLRQGLEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TGRFKIVSKE | NGVPLVAFSL | KDSSRHNEFE | VAHTLRRFGW | IVPAYTMPAD | AQHVTVLRVV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IREDFSRTLA | ERLVADFEKV | LHELDTLPAR | VHAKMANGKV | NGVKKTPEET | QREVTAYWKK |
| 490 | |||||
| LLETKKTNKN | TIC |