Q9Y7I8

PR
Gene name
zuo1 (SPBC1778.01c, SPBC30D10.01)
Protein name
Zuotin
Names
DnaJ-related protein zuo1, J protein zuo1, Ribosome-associated complex subunit zuo1
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC1778.01c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-122 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9Y7I8

Entry ID Method Resolution Chain Position Source
AF-Q9Y7I8-F1 Predicted AlphaFoldDB

No variants for Q9Y7I8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9Y7I8

No associated diseases with Q9Y7I8

3 regional properties for Q9Y7I8

Type Name Position InterPro Accession
domain DnaJ domain 96 - 167 IPR001623
conserved_site DnaJ domain, conserved site 144 - 163 IPR018253
domain Ribosome-associated complex head domain 340 - 436 IPR032003

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Hsp70 protein binding Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.
ribosome binding Binding to a ribosome.
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
'de novo' cotranslational protein folding The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.
cytoplasmic translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
regulation of translational fidelity Any process that modulates the ability of the translational apparatus to interpret the genetic code.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAGDSIQLF PPTTKQAIEA SFVPHGKISP LIKRAVEPVG PLFLAHARRQ RHGRTFSEDE
70 80 90 100 110 120
RLEVKNKVQE EVKEESEDEE EDPAMLRADP KEWKQQDHYA VLGLSKYRYK ADTEQIKKAH
130 140 150 160 170 180
LKKVLKHHPD KKAASGNIND DSFFKCIQKA YEILSDPVRR RQFDSVDENA DVEPPESTTK
190 200 210 220 230 240
ETFFELWTPV FESEARFSKK QPVPSLGTIE STRAEVDNFY NFWYNFDSWR SFEYLDKDIP
250 260 270 280 290 300
DDGESRDNKR FQEKKNRSER QKNKARDNAR LRNLVDTALA SDPRIKLFKE QEKAAKAARK
310 320 330 340 350 360
WEREAGAREA AAAAQKKKEE EERRAAEEAA AKASAAAANK KAKEDKKKAQ KRDKKVVKNA
370 380 390 400 410 420
LKDFNYFSAT DVPSAEHVDS VLKDVDVIMS KLGEGELGQL AADINAEKAA GAASVQAVFD
430 440
KFAKMFIERG SMSSADVVFF AQ