AiPD: Autoinhibited Protein Database

Q9Y2K1

Gene name	ZBTB1 (KIAA0997)
Protein name	Zinc finger and BTB domain-containing protein 1
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:22890
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

268-338 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

268-338 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9Y2K1

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9Y2K1-F1	Predicted				AlphaFoldDB

369 variants for Q9Y2K1

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA7227202 rs768617368	2	A>G		No	ClinGen ExAC gnomAD
CA390007189 rs1596699068	3	K>N		No	ClinGen Ensembl
CA261886368 rs932363469	4	P>S		No	ClinGen TOPMed
CA390007203 rs776132804 CA390007202	5	S>R		No	ClinGen ExAC gnomAD
rs1049460629 CA261886386	8	S>N		No	ClinGen TOPMed gnomAD
rs764798420 CA7227205	15	N>K		No	ClinGen ExAC gnomAD
rs1265801072 CA390007279	16	N>S		No	ClinGen gnomAD
CA7227206 rs772733173	19	E>G		No	ClinGen ExAC TOPMed gnomAD
CA390007334 rs1411738285	24	C>G		No	ClinGen gnomAD
rs1426005141 CA390007346	25	D>G		No	ClinGen gnomAD
CA390007352 rs1380051990	26	C>R		No	ClinGen gnomAD
TCGA novel	26	C>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227210 rs753255048	27	C>Y		No	ClinGen ExAC gnomAD
CA7227211 rs756458583	29	A>E		No	ClinGen ExAC gnomAD
CA390007376 rs756458583	29	A>V		No	ClinGen ExAC gnomAD
TCGA novel	31	D>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs375361085 CA261886411	32	D>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1376419163 CA390007438	38	H>Y		No	ClinGen gnomAD
CA390007493 rs1229943412	46	S>I		No	ClinGen gnomAD
rs764509235 CA7227212	47	S>A		No	ClinGen ExAC gnomAD
rs754160233 CA7227213	51	M>T		No	ClinGen ExAC gnomAD
rs150904658 CA7227214	52	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA390007539 rs1287927973	52	F>L		No	ClinGen gnomAD
TCGA novel	55	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779023330 CA7227215 COSM194035	56	H>R	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA390007595 rs1476035233	59	S>R		No	ClinGen TOPMed gnomAD
CA7227217 rs758589946	60	T>I		No	ClinGen ExAC gnomAD
rs746996420 CA7227219	61	A>T		No	ClinGen ExAC gnomAD
CA7227220 rs768564161	62	Q>H		No	ClinGen ExAC gnomAD
CA390007635 rs1438406571	66	S>N		No	ClinGen gnomAD
rs1172437193 CA390007648	68	M>L		No	ClinGen gnomAD
TCGA novel	70	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390007785 rs1566634899	86	K>E		No	ClinGen Ensembl
rs961995242 CA261886526	86	K>R		No	ClinGen Ensembl
rs776417526 CA7227221	87	I>V		No	ClinGen ExAC
rs747921093 CA390007798 CA7227222	88	M>L		No	ClinGen ExAC gnomAD
CA7227223 rs769450178	90	A>T		No	ClinGen ExAC gnomAD
CA390007889 rs1367541576	101	M>V		No	ClinGen TOPMed
rs1337447422 CA390007900	102	N>T		No	ClinGen gnomAD
CA261886570 rs972052362	105	Q>*		No	ClinGen Ensembl
rs1162328258 CA390007939	108	N>D		No	ClinGen TOPMed
CA390007950 rs1425177320	109	V>A		No	ClinGen TOPMed
rs150032061 CA7227225	112	C>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA7227226 rs770486534	113	L>I		No	ClinGen ExAC gnomAD
rs775972428 CA7227227	114	E>A		No	ClinGen ExAC gnomAD
CA7227228 rs761105445	114	E>D		No	ClinGen ExAC gnomAD
rs1026782070 CA261886598	116	I>F		No	ClinGen TOPMed
rs1482375409 CA390007996	116	I>T		No	ClinGen TOPMed
rs573689136 CA7227230	118	D>G		No	ClinGen 1000Genomes ExAC gnomAD
rs895241853 CA261886614	120	D>A		No	ClinGen TOPMed gnomAD
rs1012369488 CA261886618	121	C>R		No	ClinGen TOPMed gnomAD
CA7227232 rs762114031	121	C>S		No	ClinGen ExAC gnomAD
CA7227233 rs541812701	121	C>W		No	ClinGen ExAC TOPMed gnomAD
rs371466604 CA7227234	126	C>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs758535582 CA7227235	127	S>F		No	ClinGen ExAC gnomAD
CA7227237 rs751692094	128	S>C		No	ClinGen ExAC gnomAD
CA390008072 rs1190243539	128	S>T		No	ClinGen gnomAD
CA390008096 rs1415846669	132	S>G		No	ClinGen gnomAD
TCGA novel	134	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390008126 rs1176451344	135	N>K		No	ClinGen gnomAD
CA390008130 rs1326751227	136	S>N		No	ClinGen gnomAD
CA261886680 rs970774761	136	S>R		No	ClinGen TOPMed
CA261886681 rs978483191	139	I>L		No	ClinGen TOPMed
rs1398927934 CA390008169	141	G>A		No	ClinGen gnomAD
rs753507746 CA7227238 CA261886686	142	V>L		No	ClinGen ExAC gnomAD
CA261886691 rs1050553649	144	M>L		No	ClinGen Ensembl
CA390008194 rs781025755	145	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA7227239 rs781025755	145	Y>F		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	146	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390008218 rs1272879068	148	T>I		No	ClinGen gnomAD
CA7227242 rs777471462	151	R>*		No	ClinGen ExAC gnomAD
rs1201046098 CA390008241	152	N>K		No	ClinGen TOPMed gnomAD
CA390008238 rs1316201388	152	N>T		No	ClinGen gnomAD
CA7227243 rs749008388	154	N>K		No	ClinGen ExAC TOPMed gnomAD
rs770574476 CA7227244	155	E>K		No	ClinGen ExAC gnomAD
CA7227245 rs773794184	157	N>H		No	ClinGen ExAC gnomAD
CA390008285 rs1596699685	159	W>G		No	ClinGen Ensembl
CA390008294 rs1596699699	160	C>G		No	ClinGen Ensembl
rs376571289 CA7227246	160	C>Y		No	ClinGen ESP ExAC gnomAD
CA261886759 rs944898727	164	S>T		No	ClinGen TOPMed gnomAD
rs1199783225 CA390008337	166	T>M	Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA7227248 rs777044118	167	V>I		No	ClinGen ExAC gnomAD
rs1172231133 CA390008352	169	T>A		No	ClinGen gnomAD
rs1040562978 CA261886779	169	T>I		No	ClinGen Ensembl
CA7227249 rs762215264	171	H>R		No	ClinGen ExAC gnomAD
CA390008370 rs1404708179	172	N>Y		No	ClinGen gnomAD
CA390008379 rs1321262042	173	R>K		No	ClinGen gnomAD
rs1321262042 CA390008380	173	R>T		No	ClinGen gnomAD
CA261886824 rs903441518	175	A>S		No	ClinGen Ensembl
TCGA novel	175	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227251 rs750665345	175	A>V		No	ClinGen ExAC gnomAD
CA390008399 rs1266930086	176	D>G		No	ClinGen gnomAD
CA390008418 rs763199349	178	E>D		No	ClinGen ExAC gnomAD
rs1596699795 CA390008422	179	S>A		No	ClinGen Ensembl
TCGA novel	179	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1566635131 CA390008431	180	L>F		No	ClinGen Ensembl
CA390008482 rs145788836	187	E>D		No	ClinGen TOPMed gnomAD
TCGA novel	190	F>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA261886855 rs922069947	192	V>I		No	ClinGen TOPMed
CA7227254 rs149197614	193	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA390008524 rs1211693071	194	K>E		No	ClinGen TOPMed
TCGA novel	196	S>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1488946678 CA390008542	196	S>N		No	ClinGen TOPMed
CA7227256 rs201229691	198	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7227257 rs752638675	200	K>T		No	ClinGen ExAC gnomAD
CA7227258 rs45512391	203	T>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1289973340 CA390008603	206	E>K		No	ClinGen TOPMed
CA390008612 rs1195137273	207	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1373157156 CA390008614	207	R>H		No	ClinGen TOPMed gnomAD
CA261886881 rs146456222	209	S>L		No	ClinGen ESP
CA390008657 rs1161445906	214	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA390008663 rs1415662223	215	S>N		No	ClinGen gnomAD
rs1204885875 CA390008666	215	S>R		No	ClinGen Ensembl
CA390008699 rs1425108821	220	S>G		No	ClinGen gnomAD
CA390008701 rs1297385835	220	S>N		No	ClinGen gnomAD
rs200793780 CA7227262	232	D>G		No	ClinGen 1000Genomes ExAC gnomAD
rs771531324 CA7227264	235	V>M		No	ClinGen ExAC gnomAD
rs1391373873 CA390008839	239	T>I		No	ClinGen TOPMed
CA390008853 rs1360582519	241	R>K		No	ClinGen gnomAD
rs748667481 CA7227266	244	Y>C		No	ClinGen ExAC gnomAD
CA7227268 rs773651488	245	Q>H		No	ClinGen ExAC gnomAD
CA390008881 rs1478016681	245	Q>R		No	ClinGen TOPMed
TCGA novel	251	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1376388330 CA390008940	253	I>T		No	ClinGen TOPMed
rs1201097376 CA390008942	254	V>L		No	ClinGen TOPMed
rs566517326 CA7227272	256	I>V		No	ClinGen 1000Genomes ExAC gnomAD
CA7227273 rs759652988	258	D>G		No	ClinGen ExAC TOPMed gnomAD
rs931191863 CA261886998	259	G>E		No	ClinGen TOPMed gnomAD
CA261887008 rs879173680	260	K>E		No	ClinGen Ensembl
TCGA novel	262	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs920840885 CA390009009	263	N>K		No	ClinGen gnomAD
CA261887023 rs895017908	263	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs199815620 CA7227276	269	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7227277 rs764042806	270	E>G		No	ClinGen ExAC gnomAD
CA7227279 rs201748449	272	D>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA261887055 rs778515455	273	S>A		No	ClinGen ExAC TOPMed gnomAD
CA7227280 rs778515455	273	S>T		No	ClinGen ExAC TOPMed gnomAD
CA7227281 rs745577215	274	S>F		No	ClinGen ExAC TOPMed gnomAD
rs757917033 CA7227282	276	T>S		No	ClinGen ExAC gnomAD
TCGA novel	279	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227283 rs199745315	281	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs986585187 CA261887079	282	D>G		No	ClinGen Ensembl
rs1432503782 CA390009153	285	R>G		No	ClinGen TOPMed
CA390009160 rs1366889687	286	G>R		No	ClinGen TOPMed
CA261887098 rs910638180	287	D>E		No	ClinGen gnomAD
rs1461663680 CA390009170	287	D>G		No	ClinGen gnomAD
rs773898874 CA7227286	288	T>I		No	ClinGen ExAC gnomAD
CA390009193 rs1441366321	290	Q>H		No	ClinGen TOPMed gnomAD
rs879111753 CA261887105	291	A>G		No	ClinGen gnomAD
rs749651202 CA7227287	291	A>S		No	ClinGen ExAC gnomAD
rs774714285 CA7227289	293	D>A		No	ClinGen ExAC TOPMed gnomAD
CA390009215 rs1407010948	294	D>G		No	ClinGen TOPMed gnomAD
rs1451918615 CA390009227	296	A>S		No	ClinGen TOPMed gnomAD
CA390009233 rs1389670998	297	S>A		No	ClinGen TOPMed
CA390009235 rs1290791623	297	S>L		No	ClinGen gnomAD
CA7227290 rs759610819	299	T>A		No	ClinGen ExAC gnomAD
rs569570323 CA7227291	301	S>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1385426135 CA390009265	302	R>K		No	ClinGen gnomAD
TCGA novel	302	R>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390009268 rs1451580801 COSM1370566	303	K>Q	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA7227292 rs775384895	305	S>C		No	ClinGen ExAC gnomAD
CA390009285 rs775384895	305	S>G		No	ClinGen ExAC gnomAD
CA390009302 rs1248842017	307	V>G		No	ClinGen TOPMed
CA390009332 rs377658410	312	A>P		No	ClinGen TOPMed gnomAD
CA261887129 rs377658410	312	A>T		No	ClinGen TOPMed gnomAD
rs763987292 CA7227294	314	E>K		No	ClinGen ExAC TOPMed gnomAD
rs753820883 CA7227295	315	E>G		No	ClinGen ExAC gnomAD
rs1323702873 CA390009365	316	K>N		No	ClinGen TOPMed gnomAD
CA390009363 rs1386050692	316	K>R		No	ClinGen TOPMed gnomAD
CA390009370 rs1197910754	317	S>N		No	ClinGen gnomAD
TCGA novel	318	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148266968 CA7227296	321	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA390009426 rs1196111022	325	I>N		No	ClinGen gnomAD
rs1431650577 CA390009430	326	I>V		No	ClinGen gnomAD
rs750234161 CA7227298	327	I>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	329	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390009460 rs1430049557	330	E>K		No	ClinGen TOPMed gnomAD
CA390009461 rs1430049557	330	E>Q		No	ClinGen TOPMed gnomAD
CA390009477 rs1168656957	332	E>G		No	ClinGen gnomAD
rs17854664 CA261887162	334	I>T		No	ClinGen Ensembl
CA390009496 rs1403018905	335	P>S		No	ClinGen gnomAD
rs1336519635 CA390009508	337	D>N		No	ClinGen TOPMed
rs1389112812 CA390009552	342	F>L		No	ClinGen TOPMed gnomAD
CA261887171 rs866202435	343	N>K		No	ClinGen Ensembl
rs1384705093 CA390009561	344	I>V		No	ClinGen gnomAD
rs1287174773 CA390009571	345	I>S		No	ClinGen gnomAD
rs750991482 CA7227301	345	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	346	K>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1166825236 CA390009574	346	K>E		No	ClinGen TOPMed
rs1345561671 CA390009598	349	D>G		No	ClinGen TOPMed gnomAD
CA390009594 rs1326372684	349	D>H		No	ClinGen gnomAD
rs1217443238 CA390009613	351	D>A		No	ClinGen gnomAD
rs1054653084 CA261887181	351	D>H		No	ClinGen Ensembl
CA7227302 rs374621442	352	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs376945184 CA7227305 COSM1240683	356	T>A	oesophagus [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs376945184 CA7227304	356	T>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs779363558 CA7227306	357	D>E		No	ClinGen ExAC
rs765055352 CA261887216	358	N>K		No	ClinGen Ensembl
CA7227307 rs746266990	359	D>E		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	364	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA261887250 rs912334264	366	E>Q		No	ClinGen TOPMed
rs61985709 CA261887286	370	Y>N		No	ClinGen Ensembl
rs558358011 CA7227310	372	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
CA261887298 rs775823649	372	Y>H		No	ClinGen ExAC gnomAD
CA7227309 rs775823649	372	Y>N		No	ClinGen ExAC gnomAD
rs776546124 CA7227313	375	E>K		No	ClinGen ExAC TOPMed gnomAD
rs761667712 CA7227314	377	D>E		No	ClinGen ExAC gnomAD
CA261887344 rs150379995	379	S>N		No	ClinGen ESP TOPMed gnomAD
CA390009811 rs1367067547	379	S>R		No	ClinGen gnomAD
rs904934220 CA261887348	380	I>L		No	ClinGen TOPMed gnomAD
rs765170192 CA7227316	380	I>T		No	ClinGen ExAC gnomAD
CA390009813 rs904934220	380	I>V		No	ClinGen TOPMed gnomAD
rs1286343747 CA390009829	382	K>R		No	ClinGen TOPMed
rs75296139 CA261887362	383	S>G		No	ClinGen Ensembl
CA261887363 rs77748787	383	S>I		No	ClinGen Ensembl
rs747075448	383	S>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227318 rs368127434	384	G>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA261887371 rs368127434	384	G>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA7227319 rs765928275	385	R>K		No	ClinGen ExAC gnomAD
CA390009850 rs1350411699	386	K>E		No	ClinGen TOPMed
rs1306659860 CA390009857	387	T>S		No	ClinGen TOPMed
rs754534919 CA7227321	389	K>R		No	ClinGen ExAC gnomAD
CA390009879 rs1319884602	390	P>L		No	ClinGen TOPMed gnomAD
rs1034834331 CA261887383	390	P>S		No	ClinGen Ensembl
rs138017870 CA7227322	391	R>Q		No	ClinGen 1000Genomes ESP TOPMed gnomAD
rs780786177 CA7227324	392	M>I		No	ClinGen ExAC gnomAD
CA390009906 rs1566635845	395	S>R		No	ClinGen Ensembl
rs1566635848 CA390009916	396	A>G		No	ClinGen Ensembl
rs1566635851 CA390009926	398	E>K		No	ClinGen Ensembl
CA390009936 rs1403864141	399	R>K		No	ClinGen TOPMed
CA390009938 rs1403864141	399	R>T		No	ClinGen TOPMed
CA7227325 rs752268393	400	G>R		No	ClinGen ExAC gnomAD
CA390009946 rs1243911047	401	G>S		No	ClinGen gnomAD
CA390009961 rs1417342962	403	E>K		No	ClinGen gnomAD
rs370822062 CA390009992	407	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA7227327 rs370822062	407	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
COSM1562584 CA7227328 rs746190112	409	N>K	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA261887398 COSM3419962 rs553771237	410	N>I	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
CA390010037 rs1596700835	413	P>L		No	ClinGen Ensembl
TCGA novel	415	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772534822 CA7227329	415	Q>K		No	ClinGen ExAC gnomAD
rs375686271 CA7227330	416	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs375985563 CA7227331	417	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs930961259 CA261887415	418	A>T		No	ClinGen TOPMed gnomAD
TCGA novel	421	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227332 rs768870867	421	A>V		No	ClinGen ExAC TOPMed gnomAD
CA7227333 rs776630155	424	E>D		No	ClinGen ExAC TOPMed
rs369265245 CA7227334	429	T>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA390010145 rs1454514616	430	I>T		No	ClinGen gnomAD
rs201881548 CA7227335	430	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1566635956 CA390010184	436	S>P		No	ClinGen Ensembl
rs1375955890 CA390010223	441	A>V		No	ClinGen gnomAD
CA7227339 rs751319397	461	R>K		No	ClinGen ExAC
TCGA novel	464	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390010389 rs1405487243	465	E>K		No	ClinGen gnomAD
CA390010401 rs1254349836	466	H>R		No	ClinGen gnomAD
rs143630259 CA261887474	469	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA TOPMed gnomAD
CA390010438 rs1438266324	472	E>K		No	ClinGen gnomAD
CA390010445 rs1179346943	473	P>T		No	ClinGen gnomAD
CA390010467 rs1351841782	476	L>M		No	ClinGen TOPMed
CA7227342 rs369618687	478	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1409642790 CA390010479	478	M>V		No	ClinGen gnomAD
CA7227344 rs139193816	484	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs755725866 CA7227343	484	T>P		No	ClinGen ExAC gnomAD
rs750994819 CA7227345	486	E>G		No	ClinGen ExAC TOPMed gnomAD
CA390010534 rs1337367377	486	E>Q		No	ClinGen gnomAD
CA390010537 rs750994819	486	E>V		No	ClinGen ExAC TOPMed gnomAD
rs1156656104 CA390010552	488	M>T		No	ClinGen TOPMed
TCGA novel	491	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227347 rs576312371	494	P>H		No	ClinGen ExAC
CA7227349 rs755140145	497	Q>K		No	ClinGen ExAC gnomAD
rs781420807 CA7227350	497	Q>R		No	ClinGen ExAC gnomAD
COSM957009 rs769976585 CA7227352	499	E>K	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1476720703 CA390010639	500	I>T		No	ClinGen TOPMed
rs893822471 CA261887523	500	I>V		No	ClinGen TOPMed gnomAD
CA7227354 rs749186372	501	R>K		No	ClinGen ExAC gnomAD
CA7227356 COSM1300755 rs142978553	502	D>E	urinary_tract [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs770791427 CA7227355	502	D>G		No	ClinGen ExAC TOPMed gnomAD
CA390010659 rs1190331148	503	M>I		No	ClinGen gnomAD
rs759436083 CA7227357	503	M>R		No	ClinGen ExAC TOPMed gnomAD
CA390010657 rs759436083	503	M>T		No	ClinGen ExAC TOPMed gnomAD
CA7227358 rs767249481	504	F>V		No	ClinGen ExAC gnomAD
rs1266680791 CA390010670	505	V>L		No	ClinGen TOPMed
CA390010698 rs1176564348	509	D>H		No	ClinGen gnomAD
rs373384959 CA261887537	512	R>G		No	ClinGen ESP gnomAD
CA390010728 rs1408156278	513	D>N		No	ClinGen gnomAD
rs746038364 CA261887539	514	N>D		No	ClinGen gnomAD
rs376993813 COSM1370570 CA7227361	514	N>K	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs760246098 CA7227360	514	N>S		No	ClinGen ExAC TOPMed gnomAD
rs753292555 CA7227362	515	H>R		No	ClinGen ExAC gnomAD
CA7227363 rs758882545	517	Q>H		No	ClinGen ExAC gnomAD
CA261887553 rs990768924	518	I>V		No	ClinGen Ensembl
CA390010773 rs1217964088	519	N>S		No	ClinGen TOPMed
CA390010780 rs1369902963	520	S>T		No	ClinGen TOPMed
CA261887555 rs1029213186	523	K>T		No	ClinGen TOPMed gnomAD
rs1434706977 CA390010813	524	K>N		No	ClinGen TOPMed
TCGA novel	525	Q>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7227364 rs766813387	525	Q>H		No	ClinGen ExAC gnomAD
rs1566636177 CA390010830	527	F>L		No	ClinGen Ensembl
rs1413739086 CA390010837	528	K>E		No	ClinGen Ensembl
rs553950691 CA7227365	529	H>R		No	ClinGen 1000Genomes ExAC gnomAD
rs45572033 CA7227366	531	A>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7227367 rs778781129	535	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA390010889 rs1220336751	536	C>R		No	ClinGen gnomAD
rs748438385 CA7227368	539	C>G		No	ClinGen ExAC TOPMed gnomAD
CA390010910 rs748438385	539	C>S		No	ClinGen ExAC TOPMed gnomAD
CA390010933 rs1490744882	542	R>C		No	ClinGen TOPMed gnomAD
rs201179551 CA7227369	542	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1422300101 CA390010968	547	N>Y		No	ClinGen gnomAD
CA7227370 rs555900726	548	L>I		No	ClinGen 1000Genomes ExAC gnomAD
CA390011011 rs1419924113	553	M>I		No	ClinGen gnomAD
CA261887598 rs576257403	553	M>R		No	ClinGen 1000Genomes
CA7227371 rs749353552	555	S>G		No	ClinGen ExAC gnomAD
rs771829995 CA261887602	555	S>N		No	ClinGen Ensembl
CA261887609 rs143094641	555	S>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs148189723 CA7227373	561	M>T		No	ClinGen 1000Genomes ExAC
rs745637862 CA7227374	562	F>C		No	ClinGen ExAC gnomAD
rs1405784701 CA390011083	563	K>R		No	ClinGen gnomAD
rs939058131 CA390011104	566	I>N		No	ClinGen gnomAD
rs939058131 CA261887629	566	I>T		No	ClinGen gnomAD
rs1271326759 CA390011111	567	M>I		No	ClinGen gnomAD
rs775275102 CA7227376	567	M>K		No	ClinGen ExAC gnomAD
rs772051800 CA7227375	567	M>V		No	ClinGen ExAC TOPMed gnomAD
CA390011131 rs1486365520	570	N>D		No	ClinGen TOPMed
rs1056236881 CA261887644	571	E>K		No	ClinGen gnomAD
rs1056236881 CA390011138 COSM1515984	571	E>Q	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs760335904 CA7227377	574	H>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	576	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	580	C>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	587	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1222858551 CA390011264	588	Y>C		No	ClinGen gnomAD
CA7227380 rs761257509	605	Q>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	609	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs527521192 CA7227381	611	C>Y		No	ClinGen 1000Genomes ExAC gnomAD
rs1472431841 CA390011445	613	K>R		No	ClinGen gnomAD
CA7227383 rs759893081	614	Q>E		No	ClinGen ExAC gnomAD
CA7227384 rs767805322	618	E>Q		No	ClinGen ExAC
rs1425520953 CA390011493	620	Q>*		No	ClinGen gnomAD
rs370338474 CA261887723	622	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1382974084 CA390011509	622	R>L		No	ClinGen TOPMed
CA261887730 rs773171557	625	N>H		No	ClinGen Ensembl
COSM1300757 CA7227385 rs753077154	626	D>H	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA390011541 rs1382844073	627	M>T		No	ClinGen gnomAD
TCGA novel	633	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1319091226 CA390011621	638	I>V		No	ClinGen gnomAD
CA261887741 rs78129670	639	C>F		No	ClinGen Ensembl
rs1596701619 CA390011638	640	D>E		No	ClinGen Ensembl
CA7227389 rs757331254	640	D>G		No	ClinGen ExAC gnomAD
rs753923884 CA7227388	640	D>N		No	ClinGen ExAC TOPMed gnomAD
CA261887750 rs1049408140	643	N>D		No	ClinGen Ensembl
CA7227393 rs540324675	659	A>G		No	ClinGen 1000Genomes ExAC gnomAD
rs772139281 CA7227392	659	A>P		No	ClinGen ExAC TOPMed gnomAD
rs372364671 CA7227394	662	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA390011798 rs1181736863	663	I>M		No	ClinGen TOPMed gnomAD
CA7227396 rs776183154	663	I>V		No	ClinGen ExAC gnomAD
rs1387954698 CA390011815	666	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1387954698 CA390011816	666	V>L		No	ClinGen TOPMed
rs770430147 CA7227398	670	I>M		No	ClinGen ExAC TOPMed gnomAD
rs759981335 CA7227400	671	F>L		No	ClinGen ExAC
rs1362228600 CA390011861	672	P>Q		No	ClinGen gnomAD
rs1362228600 CA390011862	672	P>R		No	ClinGen gnomAD
CA390011910 rs1159156802	678	E>D		No	ClinGen gnomAD
CA390011944 rs1167705351	683	V>I		No	ClinGen TOPMed gnomAD
CA7227402 rs753019977	687	T>R		No	ClinGen ExAC gnomAD
TCGA novel	691	C>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA390012077 rs1333553536	701	M>I		No	ClinGen gnomAD
CA390012127 rs1298313243	708	K>R		No	ClinGen gnomAD
CA261887836 rs776152556	711	K>R		No	ClinGen TOPMed gnomAD
rs1450022846 CA390012163	713	T>N		No	ClinGen TOPMed gnomAD

No associated diseases with Q9Y2K1

9 regional properties for Q9Y2K1

Type	Name	Position	InterPro Accession
domain	BTB/POZ domain	14 - 121	IPR000210
domain	Zinc finger C2H2-type	216 - 242	IPR013087-1
domain	Zinc finger C2H2-type	421 - 443	IPR013087-2
domain	Zinc finger C2H2-type	534 - 554	IPR013087-3
domain	Zinc finger C2H2-type	578 - 605	IPR013087-4
domain	Zinc finger C2H2-type	606 - 633	IPR013087-5
domain	Zinc finger C2H2-type	634 - 656	IPR013087-6
domain	Zinc finger C2H2-type	662 - 684	IPR013087-7
domain	Zinc finger C2H2-type	686 - 713	IPR013087-8

Functions

		Description
EC Number
Subcellular Localization	Nucleus Nucleus, nucleoplasm	Localized in dot-like structures in the nucleus (PubMed:21706167) Colocalized with SMRT in nuclear bodies (PubMed:20797634) The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies (PubMed:20797634)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

5 GO annotations of cellular component

Name	Definition
centrosome	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
nuclear body	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
nuclear membrane	Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

6 GO annotations of molecular function

Name	Definition
DNA-binding transcription repressor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
K63-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.
metal ion binding	Binding to a metal ion.
protein heterodimerization activity	Binding to a nonidentical protein to form a heterodimer.
protein homodimerization activity	Binding to an identical protein to form a homodimer.
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

17 GO annotations of biological process

Name	Definition
B cell differentiation	The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
cellular response to DNA damage stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
cellular response to UV	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
chromatin remodeling	A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
DNA repair	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
innate immune response	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
mRNA transcription by RNA polymerase II	The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
negative regulation of transcription by RNA polymerase II	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
positive regulation of natural killer cell differentiation	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.
positive regulation of pro-T cell differentiation	Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.
positive regulation of T cell differentiation	Any process that activates or increases the frequency, rate or extent of T cell differentiation.
positive regulation of T cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.
protein homooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
T cell differentiation in thymus	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
thymus development	The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
translesion synthesis	The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.

178 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q08DS3	OSR1	Protein odd-skipped-related 1	Bos taurus (Bovine)	PR
Q2VWH6	FEZF2	Fez family zinc finger protein 2	Bos taurus (Bovine)	PR
A6QNZ0	ZSCAN26	Zinc finger and SCAN domain-containing protein 26	Bos taurus (Bovine)	PR
A7MBI1	ZFP69	Zinc finger protein 69 homolog	Bos taurus (Bovine)	PR
Q08705	CTCF	Transcriptional repressor CTCF	Gallus gallus (Chicken)	PR
O42409	GFI1B	Zinc finger protein Gfi-1b	Gallus gallus (Chicken)	PR
A2T6W2	ZNF449	Zinc finger protein 449	Pan troglodytes (Chimpanzee)	PR
Q9U405	grau	Transcription factor grauzone	Drosophila melanogaster (Fruit fly)	PR
Q7K0S9	sug	Zinc finger protein GLIS2 homolog	Drosophila melanogaster (Fruit fly)	PR
P20385	Cf2	Chorion transcription factor Cf2	Drosophila melanogaster (Fruit fly)	PR
Q86P48	ATbp	AT-rich binding protein	Drosophila melanogaster (Fruit fly)	PR
P28698	MZF1	Myeloid zinc finger 1	Homo sapiens (Human)	PR
Q9NTW7	ZFP64	Zinc finger protein 64	Homo sapiens (Human)	PR
O14978	ZNF263	Zinc finger protein 263	Homo sapiens (Human)	PR
O60304	ZNF500	Zinc finger protein 500	Homo sapiens (Human)	PR
P08151	GLI1	Zinc finger protein GLI1	Homo sapiens (Human)	PR
Q9UFB7	ZBTB47	Zinc finger and BTB domain-containing protein 47	Homo sapiens (Human)	PR
P18146	EGR1	Early growth response protein 1	Homo sapiens (Human)	PR
Q9Y5W3	KLF2	Krueppel-like factor 2	Homo sapiens (Human)	PR
Q9UNY5	ZNF232	Zinc finger protein 232	Homo sapiens (Human)	PR
Q96SZ4	ZSCAN10	Zinc finger and SCAN domain-containing protein 10	Homo sapiens (Human)	PR
P17028	ZNF24	Zinc finger protein 24	Homo sapiens (Human)	PR
P57682	KLF3	Krueppel-like factor 3	Homo sapiens (Human)	PR
P25490	YY1	Transcriptional repressor protein YY1	Homo sapiens (Human)	SS
O43296	ZNF264	Zinc finger protein 264	Homo sapiens (Human)	PR
P49711	CTCF	Transcriptional repressor CTCF	Homo sapiens (Human)	PR
Q9NQX1	PRDM5	PR domain zinc finger protein 5	Homo sapiens (Human)	PR
Q8TAX0	OSR1	Protein odd-skipped-related 1	Homo sapiens (Human)	PR
Q9UL58	ZNF215	Zinc finger protein 215	Homo sapiens (Human)	PR
Q8TBJ5	FEZF2	Fez family zinc finger protein 2	Homo sapiens (Human)	PR
Q96SR6	ZNF382	Zinc finger protein 382	Homo sapiens (Human)	PR
Q96IT1	ZNF496	Zinc finger protein 496	Homo sapiens (Human)	PR
Q96N95	ZNF396	Zinc finger protein 396	Homo sapiens (Human)	PR
Q9ULJ3	ZBTB21	Zinc finger and BTB domain-containing protein 21	Homo sapiens (Human)	PR
O75840	KLF7	Krueppel-like factor 7	Homo sapiens (Human)	PR
Q9H9D4	ZNF408	Zinc finger protein 408	Homo sapiens (Human)	PR
Q13127	REST	RE1-silencing transcription factor	Homo sapiens (Human)	PR
Q8IZM8	ZNF654	Zinc finger protein 654	Homo sapiens (Human)	PR
Q14526	HIC1	Hypermethylated in cancer 1 protein	Homo sapiens (Human)	PR
P17022	ZNF18	Zinc finger protein 18	Homo sapiens (Human)	PR
Q86XF7	ZNF575	Zinc finger protein 575	Homo sapiens (Human)	PR
Q06889	EGR3	Early growth response protein 3	Homo sapiens (Human)	PR
Q8NAM6	ZSCAN4	Zinc finger and SCAN domain-containing protein 4	Homo sapiens (Human)	PR
Q08ER8	ZNF543	Zinc finger protein 543	Homo sapiens (Human)	PR
P17029	ZKSCAN1	Zinc finger protein with KRAB and SCAN domains 1	Homo sapiens (Human)	PR
O95625	ZBTB11	Zinc finger and BTB domain-containing protein 11	Homo sapiens (Human)	PR
Q9NPC7	MYNN	Myoneurin	Homo sapiens (Human)	PR
Q96BV0	ZNF775	Zinc finger protein 775	Homo sapiens (Human)	PR
Q8NF99	ZNF397	Zinc finger protein 397	Homo sapiens (Human)	PR
Q63HK3	ZKSCAN2	Zinc finger protein with KRAB and SCAN domains 2	Homo sapiens (Human)	PR
Q5FWF6	ZNF789	Zinc finger protein 789	Homo sapiens (Human)	PR
Q15776	ZKSCAN8	Zinc finger protein with KRAB and SCAN domains 8	Homo sapiens (Human)	PR
Q53GI3	ZNF394	Zinc finger protein 394	Homo sapiens (Human)	PR
O95125	ZNF202	Zinc finger protein 202	Homo sapiens (Human)	PR
Q05516	ZBTB16	Zinc finger and BTB domain-containing protein 16	Homo sapiens (Human)	PR
Q9H116	GZF1	GDNF-inducible zinc finger protein 1	Homo sapiens (Human)	PR
Q8N0Y2	ZNF444	Zinc finger protein 444	Homo sapiens (Human)	PR
Q6P9G9	ZNF449	Zinc finger protein 449	Homo sapiens (Human)	PR
Q8IW36	ZNF695	Zinc finger protein 695	Homo sapiens (Human)	PR
Q5VTD9	GFI1B	Zinc finger protein Gfi-1b	Homo sapiens (Human)	PR
Q6PG37	ZNF790	Zinc finger protein 790	Homo sapiens (Human)	PR
Q9NQV6	PRDM10	PR domain zinc finger protein 10	Homo sapiens (Human)	PR
Q9Y2D9	ZNF652	Zinc finger protein 652	Homo sapiens (Human)	PR
Q9Y4E5	ZNF451	E3 SUMO-protein ligase ZNF451	Homo sapiens (Human)	PR
Q8ND82	ZNF280C	Zinc finger protein 280C	Homo sapiens (Human)	PR
Q49AA0	ZFP69	Zinc finger protein 69 homolog	Homo sapiens (Human)	PR
O43298	ZBTB43	Zinc finger and BTB domain-containing protein 43	Homo sapiens (Human)	PR
P51508	ZNF81	Zinc finger protein 81	Homo sapiens (Human)	PR
Q5JNZ3	ZNF311	Zinc finger protein 311	Homo sapiens (Human)	PR
Q9BRR0	ZKSCAN3	Zinc finger protein with KRAB and SCAN domains 3	Homo sapiens (Human)	PR
Q969J2	ZKSCAN4	Zinc finger protein with KRAB and SCAN domains 4	Homo sapiens (Human)	PR
P49910	ZNF165	Zinc finger protein 165	Homo sapiens (Human)	PR
Q9Y4X4	KLF12	Krueppel-like factor 12	Homo sapiens (Human)	PR
P10074	ZBTB48	Telomere zinc finger-associated protein	Homo sapiens (Human)	PR
P17010	ZFX	Zinc finger X-chromosomal protein	Homo sapiens (Human)	PR
Q9H5H4	ZNF768	Zinc finger protein 768	Homo sapiens (Human)	PR
Q6NSZ9	ZSCAN25	Zinc finger and SCAN domain-containing protein 25	Homo sapiens (Human)	PR
Q9Y2L8	ZKSCAN5	Zinc finger protein with KRAB and SCAN domains 5	Homo sapiens (Human)	PR
Q86UZ6	ZBTB46	Zinc finger and BTB domain-containing protein 46	Homo sapiens (Human)	PR
Q9NX65	ZSCAN32	Zinc finger and SCAN domain-containing protein 32	Homo sapiens (Human)	PR
O14771	ZNF213	Zinc finger protein 213	Homo sapiens (Human)	PR
Q8IWY8	ZSCAN29	Zinc finger and SCAN domain-containing protein 29	Homo sapiens (Human)	PR
Q8NCP5	ZBTB44	Zinc finger and BTB domain-containing protein 44	Homo sapiens (Human)	PR
Q9NQX0	PRDM6	Putative histone-lysine N-methyltransferase PRDM6	Homo sapiens (Human)	PR
Q9BU19	ZNF692	Zinc finger protein 692	Homo sapiens (Human)	PR
Q08AG5	ZNF844	Zinc finger protein 844	Homo sapiens (Human)	PR
Q6R2W3	ZBED9	SCAN domain-containing protein 3	Homo sapiens (Human)	PR
P98182	ZNF200	Zinc finger protein 200	Homo sapiens (Human)	PR
Q9UK11	ZNF223	Zinc finger protein 223	Homo sapiens (Human)	PR
O15156	ZBTB7B	Zinc finger and BTB domain-containing protein 7B	Homo sapiens (Human)	PR
Q6ZMS7	ZNF783	Zinc finger protein 783	Homo sapiens (Human)	PR
P59923	ZNF445	Zinc finger protein 445	Homo sapiens (Human)	PR
Q8N859	ZNF713	Zinc finger protein 713	Homo sapiens (Human)	PR
Q99612	KLF6	Krueppel-like factor 6	Homo sapiens (Human)	PR
Q8TD17	ZNF398	Zinc finger protein 398	Homo sapiens (Human)	PR
A6NGD5	ZSCAN5C	Zinc finger and SCAN domain-containing protein 5C	Homo sapiens (Human)	PR
Q05215	EGR4	Early growth response protein 4	Homo sapiens (Human)	PR
Q7Z398	ZNF550	Zinc finger protein 550	Homo sapiens (Human)	PR
Q96N20	ZNF75A	Zinc finger protein 75A	Homo sapiens (Human)	PR
A6NJL1	ZSCAN5B	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	PR
A1YPR0	ZBTB7C	Zinc finger and BTB domain-containing protein 7C	Homo sapiens (Human)	PR
Q9NWS9	ZNF446	Zinc finger protein 446	Homo sapiens (Human)	PR
Q96N38	ZNF714	Zinc finger protein 714	Homo sapiens (Human)	PR
Q86YH2	ZNF280B	Zinc finger protein 280B	Homo sapiens (Human)	PR
P24278	ZBTB25	Zinc finger and BTB domain-containing protein 25	Homo sapiens (Human)	PR
Q8N680	ZBTB2	Zinc finger and BTB domain-containing protein 2	Homo sapiens (Human)	PR
P41182	BCL6	B-cell lymphoma 6 protein	Homo sapiens (Human)	PR
Q9Y330	ZBTB12	Zinc finger and BTB domain-containing protein 12	Homo sapiens (Human)	PR
Q5TC79	ZBTB37	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	PR
Q9HBE1	PATZ1	POZ-, AT hook-, and zinc finger-containing protein 1	Homo sapiens (Human)	PR
P52739	ZNF131	Zinc finger protein 131	Homo sapiens (Human)	PR
Q13105	ZBTB17	Zinc finger and BTB domain-containing protein 17	Homo sapiens (Human)	PR
O08584	Klf6	Krueppel-like factor 6	Mus musculus (Mouse)	PR
Q61164	Ctcf	Transcriptional repressor CTCF	Mus musculus (Mouse)	PR
Q810A1	Znf18	Zinc finger protein 18	Mus musculus (Mouse)	PR
Q8BGS3	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Mus musculus (Mouse)	PR
Q00899	Yy1	Transcriptional repressor protein YY1	Mus musculus (Mouse)	PR
P41183	Bcl6	B-cell lymphoma 6 protein homolog	Mus musculus (Mouse)	PR
Q9DAI4	Zbtb43	Zinc finger and BTB domain-containing protein 43	Mus musculus (Mouse)	PR
O70237	Gfi1b	Zinc finger protein Gfi-1b	Mus musculus (Mouse)	PR
Q99KZ6	Znf639	Zinc finger protein 639	Mus musculus (Mouse)	PR
Q9Z1D9	Znf394	Zinc finger protein 394	Mus musculus (Mouse)	PR
Q9CXE0	Prdm5	PR domain zinc finger protein 5	Mus musculus (Mouse)	PR
P43300	Egr3	Early growth response protein 3	Mus musculus (Mouse)	PR
Q9DAU9	Znf654	Zinc finger protein 654	Mus musculus (Mouse)	PR
Q9R1Y5	Hic1	Hypermethylated in cancer 1 protein	Mus musculus (Mouse)	PR
Q8R0T2	Znf768	Zinc finger protein 768	Mus musculus (Mouse)	PR
Q9WVG7	Osr1	Protein odd-skipped-related 1	Mus musculus (Mouse)	PR
Q8BI73	Znf775	Zinc finger protein 775	Mus musculus (Mouse)	PR
Q8VCZ7	Zbtb7c	Zinc finger and BTB domain-containing protein 7C	Mus musculus (Mouse)	PR
Q91VN1	Znf24	Zinc finger protein 24	Mus musculus (Mouse)	PR
Q9DB38	Znf580	Zinc finger protein 580	Mus musculus (Mouse)	PR
A7KBS4	Zscan4d	Zinc finger and SCAN domain containing protein 4D	Mus musculus (Mouse)	PR
Q91VW9	Zkscan3	Zinc finger protein with KRAB and SCAN domains 3	Mus musculus (Mouse)	PR
P10925	Zfy1	Zinc finger Y-chromosomal protein 1	Mus musculus (Mouse)	PR
P08046	Egr1	Early growth response protein 1	Mus musculus (Mouse)	PR
Q3TTC2	Yy2	Transcription factor YY2	Mus musculus (Mouse)	PR
Q3UTQ7	Prdm10	PR domain zinc finger protein 10	Mus musculus (Mouse)	PR
Q6P3Y5	Znf280c	Zinc finger protein 280C	Mus musculus (Mouse)	PR
Q9ERU3	Znf22	Zinc finger protein 22	Mus musculus (Mouse)	PR
Q8VIG1	Rest	RE1-silencing transcription factor	Mus musculus (Mouse)	PR
Q9Z1D8	Zkscan5	Zinc finger protein with KRAB and SCAN domains 5	Mus musculus (Mouse)	PR
Q8BID6	Zbtb46	Zinc finger and BTB domain-containing protein 46	Mus musculus (Mouse)	PR
P17012	Zfx	Zinc finger X-chromosomal protein	Mus musculus (Mouse)	PR
Q9WUK6	Zbtb18	Zinc finger and BTB domain-containing protein 18	Mus musculus (Mouse)	PR
O35738	Klf12	Krueppel-like factor 12	Mus musculus (Mouse)	PR
B2RXC5	Znf382	Zinc finger protein 382	Mus musculus (Mouse)	PR
O08900	Ikzf3	Zinc finger protein Aiolos	Mus musculus (Mouse)	PR
Q5DU09	Znf652	Zinc finger protein 652	Mus musculus (Mouse)	PR
Q5RJ54	Zscan26	Zinc finger and SCAN domain-containing protein 26	Mus musculus (Mouse)	PR
Q8BLM0	Klf8	Krueppel-like factor 8	Mus musculus (Mouse)	PR
Q99JB0	Klf7	Krueppel-like factor 7	Mus musculus (Mouse)	PR
Q8R0A2	Zbtb44	Zinc finger and BTB domain-containing protein 44	Mus musculus (Mouse)	PR
P20662	Zfy2	Zinc finger Y-chromosomal protein 2	Mus musculus (Mouse)	PR
Q80VJ6	Zscan4c	Zinc finger and SCAN domain containing protein 4C	Mus musculus (Mouse)	PR
Q3URS2	Zscan4f	Zinc finger and SCAN domain containing protein 4F	Mus musculus (Mouse)	PR
Q60980	Klf3	Krueppel-like factor 3	Mus musculus (Mouse)	PR
Q8K3J5	Znf131	Zinc finger protein 131	Mus musculus (Mouse)	PR
Q9Z2K3	Znf394	Zinc finger protein 394	Rattus norvegicus (Rat)	PR
Q642B9	Znf18	Zinc finger protein 18	Rattus norvegicus (Rat)	PR
B0K011	Osr1	Protein odd-skipped-related 1	Rattus norvegicus (Rat)	PR
D3ZUU2	Gzf1	GDNF-inducible zinc finger protein 1	Rattus norvegicus (Rat)	PR
B1WBU4	Zbtb8a	Zinc finger and BTB domain-containing protein 8A	Rattus norvegicus (Rat)	PR
Q7TNK3	Znf24	Zinc finger protein 24	Rattus norvegicus (Rat)	PR
O35819	Klf6	Krueppel-like factor 6	Rattus norvegicus (Rat)	PR
Q9R1D1	Ctcf	Transcriptional repressor CTCF	Rattus norvegicus (Rat)	PR
P43301	Egr3	Early growth response protein 3	Rattus norvegicus (Rat)	PR
P08154	Egr1	Early growth response protein 1	Rattus norvegicus (Rat)	PR
A0JPL0	Znf382	Zinc finger protein 382	Rattus norvegicus (Rat)	PR
Q4KLI1	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Rattus norvegicus (Rat)	PR
A1L1J6	Znf652	Zinc finger protein 652	Rattus norvegicus (Rat)	PR
Q9SHD0	ZAT4	Zinc finger protein ZAT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9LFU0	DOT3	BTB/POZ domain-containing protein DOT3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q0P4X6	zbtb44	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
A4II20	egr1	Early growth response protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q6P882	zbtb8a.2	Zinc finger and BTB domain-containing protein 8A.2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q567C6	znf367	Zinc finger protein 367	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
A7Y7X5	znf711	Zinc finger protein 711	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MAKPSHSSYV	LQQLNNQREW	GFLCDCCIAI	DDIYFQAHKA	VLAACSSYFR	MFFMNHQHST
70	80	90	100	110	120
AQLNLSNMKI	SAECFDLILQ	FMYLGKIMTA	PSSFEQFKVA	MNYLQLYNVP	DCLEDIQDAD
130	140	150	160	170	180
CSSSKCSSSA	SSKQNSKMIF	GVRMYEDTVA	RNGNEANRWC	AEPSSTVNTP	HNREADEESL
190	200	210	220	230	240
QLGNFPEPLF	DVCKKSSVSK	LSTPKERVSR	RFGRSFTCDS	CGFGFSCEKL	LDEHVLTCTN
250	260	270	280	290	300
RHLYQNTRSY	HRIVDIRDGK	DSNIKAEFGE	KDSSKTFSAQ	TDKYRGDTSQ	AADDSASTTG
310	320	330	340	350	360
SRKSSTVESE	IASEEKSRAA	ERKRIIIKME	PEDIPTDELK	DFNIIKVTDK	DCNESTDNDE
370	380	390	400	410	420
LEDEPEEPFY	RYYVEEDVSI	KKSGRKTLKP	RMSVSADERG	GLENMRPPNN	SSPVQEDAEN
430	440	450	460	470	480
ASCELCGLTI	TEEDLSSHYL	AKHIENICAC	GKCGQILVKG	RQLQEHAQRC	GEPQDLTMNG
490	500	510	520	530	540
LGNTEEKMDL	EENPDEQSEI	RDMFVEMLDD	FRDNHYQINS	IQKKQLFKHS	ACPFRCPNCG
550	560	570	580	590	600
QRFETENLVV	EHMSSCLDQD	MFKSAIMEEN	ERDHRRKHFC	NLCGKGFYQR	CHLREHYTVH
610	620	630	640	650	660
TKEKQFVCQT	CGKQFLRERQ	LRLHNDMHKG	MARYVCSICD	QGNFRKHDHV	RHMISHLSAG
670	680	690	700	710
ETICQVCFQI	FPNNEQLEQH	MDVHLYTCGI	CGAKFNLRKD	MRSHYNAKHL	KRT