Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9W6D8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9W6D8-F1 | Predicted | AlphaFoldDB |
No variants for Q9W6D8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9W6D8 | |||||
No associated diseases with Q9W6D8
5 regional properties for Q9W6D8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Helix-turn-helix motif | 124 - 149 | IPR000047 |
| domain | Homeobox domain | 93 - 157 | IPR001356 |
| conserved_site | Homeobox, conserved site | 128 - 151 | IPR017970 |
| domain | Homeobox domain, metazoa | 117 - 128 | IPR020479-1 |
| domain | Homeobox domain, metazoa | 132 - 151 | IPR020479-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II transcription regulatory region sequence-specific DNA binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9DED6 | BARX1B | Homeobox protein BarH-like 1b | Gallus gallus (Chicken) | PR |
| Q9HBU1 | BARX1 | Homeobox protein BarH-like 1 | Homo sapiens (Human) | PR |
| Q9ER42 | Barx1 | Homeobox protein BarH-like 1 | Mus musculus (Mouse) | PR |
| Q6H6S3 | HOX24 | Homeobox-leucine zipper protein HOX24 | Oryza sativa subsp japonica (Rice) | PR |
| Q7XUJ5 | HOX22 | Homeobox-leucine zipper protein HOX22 | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| ANERPPGSCS | SSGCRRCCRP | GPYHSHLAVL | KAEQAAVFKF | PLAPLGCSGL | GSALLAAGPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MPGPAGASHL | PLELQLRGKL | EAAGSGEPGS | KAKKGRRSRT | VFTELQLMGL | EKRFEKQKYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| STPDRIDLAE | SLGLSQLQVK | TWYQNRRMKW | KKIVLQGGGL | ESPTKPKGRP | KKNSIPSSEQ |
| 190 | 200 | ||||
| LSEQERAKET | EKPPESPGEP | SERQQEE |