Q9VL52
Gene name |
SoYb (CG31755) |
Protein name |
Putative ATP-dependent RNA helicase SoYb |
Names |
Sister of Yb |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG31755 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9VL52
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9VL52-F1 | Predicted | AlphaFoldDB |
No variants for Q9VL52
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9VL52 | |||||
No associated diseases with Q9VL52
3 regional properties for Q9VL52
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Tudor domain | 8 - 117 | IPR002999-1 |
| domain | Tudor domain | 928 - 1043 | IPR002999-2 |
| domain | RNA helicase, DEAD-box type, Q motif | 477 - 505 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| Yb body | A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| germ-line stem cell division | The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. |
| negative regulation of transposition, RNA-mediated | Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VNP5 | BoYb | Putative ATP-dependent RNA helicase BoYb | Drosophila melanogaster (Fruit fly) | PR |
| Q7L014 | DDX46 | Probable ATP-dependent RNA helicase DDX46 | Homo sapiens (Human) | PR |
| Q569Z5 | Ddx46 | Probable ATP-dependent RNA helicase DDX46 | Mus musculus (Mouse) | PR |
| Q62780 | Ddx46 | Probable ATP-dependent RNA helicase DDX46 | Rattus norvegicus (Rat) | PR |
| Q8H0U8 | RH42 | DEAD-box ATP-dependent RNA helicase 42 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEHQLDPDQE | ESILITHFVN | PHQFSYVRCI | DVENSAMLVR | QIEQDLKDYC | SSERTKQVYV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EDERVIVRYQ | RWSPPKLVRG | VVRRRQNEEY | LVWILDYGFN | LCCSVWDLWP | LPDHLSRSLC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFKEGGVALI | APHSGSVWSR | SAIESLDKQL | EDANQLTFQV | VHRGKSNRNF | GLLKFRSSCQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TEDAANFLIK | QDQGRCKETL | TMAIPYEDIS | FEKAEINDMA | IDTRPRLRRI | LELVVLLSEN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKESTPTPSA | IQQKKLDALL | QSHETYLIPN | SVKLLSKVQS | ISESSMQTAL | ANRSKQISKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LPHKANQSED | NRKKEVKYLE | SENLSECLSK | VKLSSYQQKN | TDSSTLSGPR | NLASSSTNSN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SNVRKSMTLF | KSSGAHLTTS | LSVPLTENCT | NQSNNRTVVF | SMDKMEQIFN | DMLGKNPSER |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SVQKNRSQMP | NSNVSTTKRC | VEKMHVCRSE | NMGDRKPSVC | LKHLVLAHSP | EPVNPVTSYK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ELPLGNTILN | AMDDLNFQTP | LPTQIYAWPH | LVNRGSLVLV | NPSGTGRSWS | YLPVICSSVL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SSFENVTSNL | DTRIAPGPLA | ILIVDSVENA | KKLASHCEFL | MKDFNTQNLK | VVNTHAHSMM |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DVYMMLLNSC | GVLVTTLAHL | NNILSNELPL | VNPTRLEFII | FDDYDRKRLD | NAELLKEVFQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KVNSIGGLSK | QLVLVAQQWH | SERFQKLLNR | TTKPLILFGD | FLEAALYGGL | KFNVTLRSSA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LKARQLLDIL | AEQDGSKKRT | LIYCKNQMEL | EELSAILIEA | GLQCVDISKA | QNQSPNRLML |
| 790 | 800 | 810 | 820 | 830 | 840 |
| VDDSQVRKQL | PVRNIQLLIH | FSLPESWLRF | SRRFHTMADN | IRNLFTKPIG | RGQDLITYIL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| MDENNAKEWP | RIMKFLQDHG | LTTQSMPDSE | QQLDNTLPYC | PYKLSNGNCN | RNQCNKRHHF |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LKTDLPKIGN | PLLQPGTLIR | CKFLKAYDPA | HMAVMPMKYK | SKDSTIWIDV | PYPSYPSTLV |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| FKMSFGVPRK | VHNPCKINDV | CFVQHKELLS | RVRIVDNPAR | PQVTVQLMDY | GTELLQVKAS |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| QLLECPEQFR | DLQQLAMDIR | LSGLAGSGQG | GMWSTDSIQW | VQDRFADINE | EIMQITVDFG |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| VLDVAYVKEI | ALIEECPTML | TSVYKTFLRK | ELLRQGFAKI | DSTSILELRA | IHEQWKQEME |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| ELRANKENIV | CSSTDLDNRD | SKITSLQNKQ | ATCSSGKEED | LNPVETPLII | ASPNSNETLE |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| ERKHVSDKVQ | NKIDELNDFN | KSVEIEHVQD | ASPLDSSTAL | INTLIHELNT | KSPTKKKNTQ |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| EFIKNIVHED | ETQSIHHEIS | SSTNSLKQDK | TIVVGPQDPP | KELFLQYLNC | ATKSRESVYP |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| MVKWHQTLTH | IELVVEQQML | EYKLGLDGNT | LEYKVNETTP | PQRFILNLLG | EVRIDSVKQH |
| 1390 | 1400 | 1410 | 1420 | 1430 | 1440 |
| GYYLHIKLTK | VGLLFHWPTL | LNSLYVQKHA | HWLIYDSERS | HGPPPSFGLV | LWEGYLTHKK |
| 1450 | 1460 | 1470 | |||
| TKSYSDSESS | EFSSTPEDFI | EPGVEYCEMD | SNLYED |