Q9UN19
PR
Gene name |
DAPP1 (BAM32, HSPC066) |
Protein name |
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide |
Names |
hDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:27071 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q9UN19
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1FAO | X-ray | 180 A | A | 148-273 | PDB |
| 1FB8 | X-ray | 240 A | A | 148-273 | PDB |
| AF-Q9UN19-F1 | Predicted | AlphaFoldDB |
165 variants for Q9UN19
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs1419135132 CA357556146 |
4 | A>V | No |
ClinGen TOPMed |
|
|
CA357556147 rs1322733149 |
5 | E>K | No |
ClinGen gnomAD |
|
| TCGA novel | 8 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3022788 rs757550910 |
8 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs781263514 CA3022790 |
10 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs1316260255 CA357556362 |
10 | K>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs750517647 CA3022791 |
11 | M>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 11 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357556405 rs1266285786 |
12 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
rs192454033 CA3022794 |
15 | D>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA102673222 rs924134918 |
15 | D>V | No |
ClinGen TOPMed |
|
|
rs1488938032 CA357556549 |
16 | P>T | No |
ClinGen gnomAD |
|
|
CA357556701 rs1260351059 |
21 | S>N | No |
ClinGen gnomAD |
|
|
rs778726455 CA3022796 |
21 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs747880443 CA3022797 |
23 | S>A | No |
ClinGen ExAC gnomAD |
|
|
CA102673234 rs373752102 |
24 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs772675090 CA3022799 |
25 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1361063932 CA357556947 |
27 | A>G | No |
ClinGen gnomAD |
|
|
rs760245627 CA3022800 |
28 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs900592526 CA102673242 |
32 | D>N | No |
ClinGen TOPMed |
|
|
CA357560024 rs1291040868 |
35 | W>* | No |
ClinGen TOPMed gnomAD |
|
|
CA357560033 rs1291040868 |
35 | W>C | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 37 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357560110 rs1314674975 |
38 | G>D | No |
ClinGen gnomAD |
|
|
rs770680155 CA3022818 |
38 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs969041709 CA102681032 |
40 | L>F | No |
ClinGen TOPMed |
|
|
CA3022819 rs776332284 |
42 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA357560211 rs1214491721 |
43 | H>Y | No |
ClinGen TOPMed |
|
|
CA3022820 rs200313632 |
44 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA357560247 rs1316900852 |
44 | A>V | No |
ClinGen gnomAD |
|
|
rs554960188 CA3022825 |
55 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1469469055 CA357560468 |
55 | D>N | No |
ClinGen gnomAD |
|
|
CA102681059 rs866782436 |
56 | G>D | No |
ClinGen Ensembl |
|
|
CA3022826 COSM225549 rs760935963 |
56 | G>S | NS [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1238421501 CA357560497 |
57 | S>R | No |
ClinGen gnomAD |
|
|
CA357560591 rs1578356067 |
62 | D>G | No |
ClinGen Ensembl |
|
|
rs1037696561 CA102681063 |
62 | D>H | No |
ClinGen TOPMed |
|
|
rs371733623 CA3022827 |
63 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1387030622 CA357560672 |
65 | E>D | No |
ClinGen gnomAD |
|
|
rs749215963 CA102681064 |
66 | T>P | No |
ClinGen Ensembl |
|
|
rs920634897 CA102681067 |
67 | T>I | No |
ClinGen TOPMed |
|
|
rs754986506 CA3022829 |
68 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752528304 CA3022831 |
72 | L>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs746781776 CA3022834 |
73 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA357500423 rs1200475300 |
75 | R>S | No |
ClinGen Ensembl |
|
|
CA3022850 rs531841086 |
76 | A>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs267599964 CA102613668 |
83 | F>C | No |
ClinGen Ensembl |
|
|
rs541741416 CA102613670 |
84 | H>L | No |
ClinGen ExAC gnomAD |
|
|
rs541741416 CA3022851 |
84 | H>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 87 | Y>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357500588 rs1212400726 |
90 | Y>C | No |
ClinGen gnomAD |
|
|
rs757057345 CA3022852 |
90 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA102613698 rs937899470 |
91 | S>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1322025255 CA357500626 |
93 | K>E | No |
ClinGen gnomAD |
|
| TCGA novel | 95 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357500700 rs1223574998 |
97 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs763855611 CA357500724 |
98 | E>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 101 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3022855 rs559809943 |
102 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 110 | A>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1166311370 CA357500928 |
111 | N>Y | No |
ClinGen gnomAD |
|
|
rs748817839 CA3022857 |
113 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA357500960 rs748817839 |
113 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1364232361 CA357500999 |
116 | G>R | No |
ClinGen gnomAD |
|
|
rs747389030 CA3022860 |
119 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs746234384 CA3022883 |
120 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 125 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1443109256 CA357504825 |
127 | H>Y | No |
ClinGen gnomAD |
|
|
CA800771110 rs1227177668 |
129 | Y>* | No |
ClinGen TOPMed |
|
|
CA3022889 rs761887882 |
130 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs767547987 CA3022890 |
131 | R>* | No |
ClinGen ExAC gnomAD |
|
|
CA357504944 rs1304171618 |
132 | K>Q | No |
ClinGen TOPMed |
|
|
CA3022891 rs750309314 |
133 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs760451809 CA3022892 |
134 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA357505095 COSM1633384 rs1402230230 COSM1633385 |
138 | I>V | liver [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1399985064 CA357505186 |
140 | E>G | No |
ClinGen TOPMed |
|
|
rs908547761 CA102623903 |
141 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs753481523 CA3022894 |
142 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA3022896 rs376041630 |
143 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs548601611 CA3022895 |
143 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA357505255 rs1333878672 |
144 | V>I | No |
ClinGen gnomAD |
|
|
rs1238193992 CA357505329 |
146 | T>I | No |
ClinGen gnomAD |
|
|
COSM1049463 rs752181928 COSM1049462 CA3022897 |
147 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1345742408 CA357505422 |
150 | T>I | No |
ClinGen gnomAD |
|
|
CA357505471 rs1416262925 |
153 | T>K | No |
ClinGen TOPMed |
|
|
rs1225437924 CA357505522 |
155 | D>V | No |
ClinGen gnomAD |
|
|
rs901853231 CA357505545 |
156 | D>E | No |
ClinGen gnomAD |
|
|
CA102623923 rs1014853943 |
156 | D>V | No |
ClinGen gnomAD |
|
|
CA357505550 rs1199627336 |
157 | L>V | No |
ClinGen gnomAD |
|
|
CA357505610 rs1181646090 COSM1049465 |
161 | A>S | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA357505621 rs1481129131 |
163 | S>P | No |
ClinGen gnomAD |
|
|
rs368943931 CA3022912 |
165 | G>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1049466 rs368943931 COSM1049467 CA102629869 |
165 | G>D | endometrium [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs368943931 CA357507323 |
165 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA357507347 rs1422617710 |
169 | G>S | No |
ClinGen gnomAD |
|
|
rs747022017 CA102629886 |
171 | L>F | No |
ClinGen Ensembl |
|
|
CA102629891 rs747022017 |
171 | L>I | No |
ClinGen Ensembl |
|
|
rs1270781082 CA357507366 |
172 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA357507384 rs1302509845 |
174 | Q>L | No |
ClinGen gnomAD |
|
|
rs759283422 CA3022914 |
175 | G>* | No |
ClinGen ExAC gnomAD |
|
|
rs1400705615 CA357507399 |
176 | G>V | No |
ClinGen gnomAD |
|
|
CA357507406 rs1297979130 |
177 | L>P | No |
ClinGen gnomAD |
|
|
CA357507412 rs1227111285 |
178 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA357507414 rs1227111285 |
178 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA102630665 rs964769892 |
180 | T>S | No |
ClinGen Ensembl |
|
|
CA357507543 rs1450903455 |
186 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA3022939 rs751007881 |
187 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 190 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1052230460 CA102630674 |
193 | L>V | No |
ClinGen TOPMed |
|
|
rs892325298 CA357507593 |
194 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA102630675 rs892325298 |
194 | K>T | No |
ClinGen TOPMed gnomAD |
|
|
CA357507617 rs1238509248 |
197 | K>R | No |
ClinGen gnomAD |
|
|
CA3022942 rs754233433 |
198 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA357507625 rs1331078282 |
198 | D>G | No |
ClinGen TOPMed |
|
|
CA102630681 rs1022656109 |
200 | M>T | No |
ClinGen TOPMed |
|
|
CA357507659 rs1223496061 |
201 | S>L | No |
ClinGen TOPMed |
|
|
CA3022964 rs753089835 |
202 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1043952547 CA102631105 |
203 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
rs867913952 CA357507678 |
204 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs867913952 CA102631107 |
204 | P>Q | No |
ClinGen gnomAD |
|
|
CA3022966 rs201164049 |
205 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1020531964 CA102631119 |
206 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1272082115 CA357507702 |
209 | D>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1560709898 CA357507710 |
210 | L>V | No |
ClinGen Ensembl |
|
| TCGA novel | 212 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 217 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357507768 rs3737484 |
218 | F>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA357507763 rs1392853925 |
218 | F>L | No |
ClinGen TOPMed |
|
|
rs745769238 CA3022970 |
219 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA3022972 rs769693769 |
221 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs1383892303 CA357508928 |
233 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs764393680 CA3022989 |
235 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA3022990 rs751687566 |
236 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA357509046 rs1560711472 |
237 | F>S | No |
ClinGen Ensembl |
|
|
CA357509102 rs1398470642 |
238 | Y>C | No |
ClinGen gnomAD |
|
|
rs1035507327 CA102632416 |
241 | A>G | No |
ClinGen Ensembl |
|
|
CA357509181 rs1477410465 |
241 | A>T | No |
ClinGen TOPMed |
|
|
CA357509255 rs756108686 |
244 | G>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3022994 rs756108686 CA357509252 |
244 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA357509391 rs1454350205 |
250 | W>L | No |
ClinGen gnomAD |
|
|
CA357509400 rs1334504272 |
251 | I>V | No |
ClinGen gnomAD |
|
|
CA102632454 rs746077539 |
254 | L>V | No |
ClinGen Ensembl |
|
|
rs779897890 CA3022995 |
255 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3022996 rs749093298 |
255 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 255 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357509498 rs1281216241 |
256 | W>* | No |
ClinGen gnomAD |
|
|
CA357509699 rs1243107994 |
260 | Q>* | No |
ClinGen gnomAD |
|
|
CA102633992 rs867048585 |
260 | Q>H | No |
ClinGen Ensembl |
|
| TCGA novel | 261 | I>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3023041 rs187147584 |
263 | K>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3023042 rs780620801 |
264 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs924399278 CA102634013 |
265 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
CA357509739 rs1259247322 |
266 | N>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs745376074 CA3023043 |
269 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs879122474 CA102634014 |
269 | E>Q | No |
ClinGen Ensembl |
|
|
rs942470925 CA102634015 |
270 | G>S | No |
ClinGen Ensembl |
|
|
rs769044015 CA3023044 |
271 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3023046 rs200809136 |
273 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3023048 rs371219607 |
273 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3023047 rs371219607 |
273 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1249025727 CA357509791 |
275 | R>Q | No |
ClinGen TOPMed |
|
|
CA3023049 rs760935827 |
275 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA357509797 rs1386810500 |
276 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1231647342 CA357509822 |
279 | F>L | No |
ClinGen TOPMed |
|
|
rs759595702 CA3023052 |
280 | K>N | No |
ClinGen ExAC gnomAD |
No associated diseases with Q9UN19
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphatidylinositol-3,4,5-trisphosphate binding | Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. |
| phosphatidylinositol-3,4-bisphosphate binding | Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions. |
| phospholipid binding | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein dephosphorylation | The process of removing one or more phosphoric residues from a protein. |
| signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A4FUB7 | GIN1 | Gypsy retrotransposon integrase-like protein 1 | Bos taurus (Bovine) | PR |
| Q6ZNG9 | KRBA2 | KRAB-A domain-containing protein 2 | Homo sapiens (Human) | PR |
| Q9P2P1 | NYNRIN | Protein NYNRIN | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| Q9QXT1 | Dapp1 | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide | Mus musculus (Mouse) | PR |
| Q94KB1 | MLO14 | MLO-like protein 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80580 | MLO15 | MLO-like protein 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SMP1 | XTH11 | Probable xyloglucan endotransglucosylase/hydrolase protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49621 | MLO1 | MLO-like protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FK75 | At5g45670 | GDSL esterase/lipase At5g45670 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FI00 | MLO11 | MLO-like protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGRAELLEGK | MSTQDPSDLW | SRSDGEAELL | QDLGWYHGNL | TRHAAEALLL | SNGCDGSYLL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDSNETTGLY | SLSVRAKDSV | KHFHVEYTGY | SFKFGFNEFS | SLKDFVKHFA | NQPLIGSETG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TLMVLKHPYP | RKVEEPSIYE | SVRVHTAMQT | GRTEDDLVPT | APSLGTKEGY | LTKQGGLVKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WKTRWFTLHR | NELKYFKDQM | SPEPIRILDL | TECSAVQFDY | SQERVNCFCL | VFPFRTFYLC |
| 250 | 260 | 270 | |||
| AKTGVEADEW | IKILRWKLSQ | IRKQLNQGEG | TIRSRSFIFK |