Q9T048

PR
Gene name
At4g27190 (T24A18.140)
Protein name
Disease resistance protein At4g27190
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G27190
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

43-176 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9T048

Entry ID Method Resolution Chain Position Source
AF-Q9T048-F1 Predicted AlphaFoldDB

45 variants for Q9T048

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_13623909_C_G 9 G>A No 1000Genomes
ENSVATH12255066 16 Y>C No 1000Genomes
tmp_4_13623760_T_C 59 T>A No 1000Genomes
tmp_4_13623717_C_T 73 R>K No 1000Genomes
ENSVATH06783627 79 I>T No 1000Genomes
ENSVATH09500202 119 I>V No 1000Genomes
ENSVATH06783626 129 S>P No 1000Genomes
ENSVATH06783621 146 T>A No 1000Genomes
ENSVATH12255022 192 G>A No 1000Genomes
ENSVATH06783612 226 T>S No 1000Genomes
ENSVATH06783610 261 D>Y No 1000Genomes
tmp_4_13623085_A_G 284 F>L No 1000Genomes
ENSVATH00540778 286 E>D No 1000Genomes
tmp_4_13622994_T_G 314 N>T No 1000Genomes
ENSVATH09500121 395 K>N No 1000Genomes
ENSVATH02929919 401 C>F No 1000Genomes
tmp_4_13622731_C_T 402 A>T No 1000Genomes
ENSVATH09500120 415 V>L No 1000Genomes
ENSVATH09500112 428 L>H No 1000Genomes
ENSVATH00540777 455 D>A No 1000Genomes
ENSVATH00540775 480 D>G No 1000Genomes
ENSVATH14301242 519 L>V No 1000Genomes
ENSVATH12254973 525 V>E No 1000Genomes
ENSVATH09500057 527 T>A No 1000Genomes
ENSVATH12254972 536 F>L No 1000Genomes
ENSVATH09500050 536 F>S No 1000Genomes
ENSVATH12254970 563 K>T No 1000Genomes
ENSVATH09500043 583 D>E No 1000Genomes
ENSVATH09500040 586 K>N No 1000Genomes
ENSVATH08368288 589 K>E No 1000Genomes
tmp_4_13622109_A_G 609 I>T No 1000Genomes
ENSVATH09500027 623 R>I No 1000Genomes
ENSVATH06783582 632 H>R No 1000Genomes
ENSVATH06783577 680 R>C No 1000Genomes
ENSVATH09499993 759 A>V No 1000Genomes
tmp_4_13621564_C_A 791 E>* No 1000Genomes
tmp_4_13621559_C_G 792 M>I No 1000Genomes
tmp_4_13621546_T_C 797 T>A No 1000Genomes
ENSVATH12254940 846 C>Y No 1000Genomes
ENSVATH02929909 861 I>F No 1000Genomes
ENSVATH02929908 863 N>K No 1000Genomes
tmp_4_13621293_G_A 881 A>V No 1000Genomes
tmp_4_13621287_A_G 883 L>S No 1000Genomes
tmp_4_13621176_T_A 920 E>V No 1000Genomes
tmp_4_13620997_C_T 980 A>T No 1000Genomes

No associated diseases with Q9T048

5 regional properties for Q9T048

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 527 - 535 IPR000629
domain Helicase, C-terminal 592 - 753 IPR001650
domain DEAD/DEAH box helicase domain 396 - 568 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 391 - 596 IPR014001
domain RNA helicase, DEAD-box type, Q motif 372 - 400 IPR014014

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ADP binding Binding to ADP, adenosine 5'-diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

20 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F1MHT9 NLRC4 NLR family CARD domain-containing protein 4 Bos taurus (Bovine) SS
O14727 APAF1 Apoptotic protease-activating factor 1 Homo sapiens (Human) EV
Q9NPP4 NLRC4 NLR family CARD domain-containing protein 4 Homo sapiens (Human) SS
Q3UP24 Nlrc4 NLR family CARD domain-containing protein 4 Mus musculus (Mouse) EV
F1M649 Nlrc4 NLR family CARD domain-containing protein 4 Rattus norvegicus (Rat) SS
O22727 At1g61190 Probable disease resistance protein At1g61190 Arabidopsis thaliana (Mouse-ear cress) PR
O64790 At1g61300 Probable disease resistance protein At1g61300 Arabidopsis thaliana (Mouse-ear cress) PR
O64973 RPS5 Disease resistance protein RPS5 Arabidopsis thaliana (Mouse-ear cress) PR
P0C8S1 RPP8L2 Probable disease resistance RPP8-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
P60838 SUMM2 Disease resistance protein SUMM2 Arabidopsis thaliana (Mouse-ear cress) PR
Q38834 RPP13L4 Disease resistance RPP13-like protein 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q39214 RPM1 Disease resistance protein RPM1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8W3K3 At1g58400 Putative disease resistance protein At1g58400 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C646 RXW24L Probable disease resistance protein RXW24L Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJB5 RPP8L3 Disease resistance RPP8-like protein 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRR4 RPPL1 Putative disease resistance RPP13-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9XIF0 At1g59780 Putative disease resistance protein At1g59780 Arabidopsis thaliana (Mouse-ear cress) PR
O64789 At1g61310 Probable disease resistance protein At1g61310 Arabidopsis thaliana (Mouse-ear cress) PR
Q940K0 UNI Disease resistance protein UNI Arabidopsis thaliana (Mouse-ear cress) PR
Q9I9H8 apaf1 Apoptotic protease-activating factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) SS
10 20 30 40 50 60
MECCAPVIGE ILRLMYESTF SRVANAIKFK SNVKALNESL ERLTELKGNM SEDHETLLTK
70 80 90 100 110 120
DKPLRLKLMR WQREAEEVIS KARLKLEERV SCGMSLRPRM SRKLVKILDE VKMLEKDGIE
130 140 150 160 170 180
FVDMLSVEST PERVEHVPGV SVVHQTMASN MLAKIRDGLT SEKAQKIGVW GMGGVGKTTL
190 200 210 220 230 240
VRTLNNKLRE EGATQPFGLV IFVIVSKEFD PREVQKQIAE RLDIDTQMEE SEEKLARRIY
250 260 270 280 290 300
VGLMKERKFL LILDDVWKPI DLDLLGIPRT EENKGSKVIL TSRFLEVCRS MKTDLDVRVD
310 320 330 340 350 360
CLLEEDAWEL FCKNAGDVVR SDHVRKIAKA VSQECGGLPL AIITVGTAMR GKKNVKLWNH
370 380 390 400 410 420
VLSKLSKSVP WIKSIEEKIF QPLKLSYDFL EDKAKFCFLL CALFPEDYSI EVTEVVRYWM
430 440 450 460 470 480
AEGFMEELGS QEDSMNEGIT TVESLKDYCL LEDGDRRDTV KMHDVVRDFA IWIMSSSQDD
490 500 510 520 530 540
SHSLVMSGTG LQDIRQDKLA PSLRRVSLMN NKLESLPDLV EEFCVKTSVL LLQGNFLLKE
550 560 570 580 590 600
VPIGFLQAFP TLRILNLSGT RIKSFPSCSL LRLFSLHSLF LRDCFKLVKL PSLETLAKLE
610 620 630 640 650 660
LLDLCGTHIL EFPRGLEELK RFRHLDLSRT LHLESIPARV VSRLSSLETL DMTSSHYRWS
670 680 690 700 710 720
VQGETQKGQA TVEEIGCLQR LQVLSIRLHS SPFLLNKRNT WIKRLKKFQL VVGSRYILRT
730 740 750 760 770 780
RHDKRRLTIS HLNVSQVSIG WLLAYTTSLA LNHCQGIEAM MKKLVSDNKG FKNLKSLTIE
790 800 810 820 830 840
NVIINTNSWV EMVSTNTSKQ SSDILDLLPN LEELHLRRVD LETFSELQTH LGLKLETLKI
850 860 870 880 890 900
IEITMCRKLR TLLDKRNFLT IPNLEEIEIS YCDSLQNLHE ALLYHQPFVP NLRVLKLRNL
910 920 930 940 950 960
PNLVSICNWG EVWECLEQVE VIHCNQLNCL PISSTCGRIK KIKGELSWWE RLEWDDPSAL
970 980
TTVQPFFNPV REVPLLIADA TTQML