Q9T012

PR
Gene name
HMGB13 (NFD13, At4g11080, F2P3.3, T22B4.60)
Protein name
High mobility group B protein 13
Names
Nucleosome/chromatin assembly factor group D 13
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G11080
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-155 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9T012

Entry ID Method Resolution Chain Position Source
AF-Q9T012-F1 Predicted AlphaFoldDB

91 variants for Q9T012

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_6763265_G_A 3 T>I No 1000Genomes
ENSVATH14131439 4 V>I No 1000Genomes
tmp_4_6763259_G_A 5 S>F No 1000Genomes
tmp_4_6763168_G_T 35 D>E No 1000Genomes
ENSVATH00489139 35 D>G No 1000Genomes
tmp_4_6763159_T_A 38 K>N No 1000Genomes
ENSVATH06612863 39 E>* No 1000Genomes
ENSVATH06612863 39 E>K No 1000Genomes
ENSVATH02784008 40 T>S No 1000Genomes
tmp_4_6763129_C_T 48 M>I No 1000Genomes
tmp_4_6763103_A_G 57 M>T No 1000Genomes
ENSVATH06612862 64 T>I No 1000Genomes
tmp_4_6763080_C_G 65 E>Q No 1000Genomes
ENSVATH11486070 66 D>E No 1000Genomes
ENSVATH11486071 66 D>Y No 1000Genomes
ENSVATH06612860 80 V>D No 1000Genomes
tmp_4_6763027_C_A 82 Q>H No 1000Genomes
ENSVATH11486069 82 Q>L No 1000Genomes
ENSVATH02784003 88 E>K No 1000Genomes
ENSVATH06612859 93 Q>L No 1000Genomes
tmp_4_6762975_G_A 100 P>S No 1000Genomes
ENSVATH00489131 103 T>I No 1000Genomes
ENSVATH02783959 104 F>Y No 1000Genomes
ENSVATH00489130 111 A>V No 1000Genomes
ENSVATH06612848 117 K>M No 1000Genomes
ENSVATH06612846 126 C>Y No 1000Genomes
ENSVATH00489129 127 A>T No 1000Genomes
ENSVATH00489128 127 A>V No 1000Genomes
ENSVATH00489127 129 T>I No 1000Genomes
tmp_4_6762362_G_A 133 S>L No 1000Genomes
ENSVATH14131364 137 I>L No 1000Genomes
ENSVATH00489125 149 K>N No 1000Genomes
ENSVATH08326129 153 E>A No 1000Genomes
ENSVATH02783952 153 E>D No 1000Genomes
ENSVATH09561924 169 G>A No 1000Genomes
ENSVATH09561925 169 G>R No 1000Genomes
ENSVATH09561922 170 I>L No 1000Genomes
ENSVATH09561921 170 I>M No 1000Genomes
ENSVATH09561922 170 I>V No 1000Genomes
ENSVATH02783948 171 S>N No 1000Genomes
ENSVATH02783947 172 A>V No 1000Genomes
ENSVATH02783943 188 A>V No 1000Genomes
ENSVATH02783942 190 L>I No 1000Genomes
tmp_4_6762186_C_T 192 V>I No 1000Genomes
ENSVATH02783940 216 M>I No 1000Genomes
tmp_4_6762114_T_C 216 M>V No 1000Genomes
tmp_4_6762102_C_A 220 D>Y No 1000Genomes
ENSVATH02783939 229 A>G No 1000Genomes
ENSVATH02783937 231 H>Q No 1000Genomes
ENSVATH02783938 231 H>Y No 1000Genomes
ENSVATH14131363 234 K>N No 1000Genomes
tmp_4_6761920_G_T 251 S>Y No 1000Genomes
ENSVATH00489118 268 N>K No 1000Genomes
ENSVATH06612844 268 N>Y No 1000Genomes
ENSVATH00489113 277 M>I No 1000Genomes
ENSVATH02783929 278 A>T No 1000Genomes
ENSVATH14131361 282 W>* No 1000Genomes
ENSVATH00489112 289 K>Q No 1000Genomes
ENSVATH00489111 295 Q>K No 1000Genomes
ENSVATH06612841 318 E>K No 1000Genomes
ENSVATH02783922 328 E>K No 1000Genomes
ENSVATH11485852 330 M>I No 1000Genomes
ENSVATH00489107 332 L>V No 1000Genomes
tmp_4_6761497_G_A 333 H>Y No 1000Genomes
ENSVATH02783921 351 I>M No 1000Genomes
tmp_4_6761351_C_G 353 K>N No 1000Genomes
ENSVATH02783916 357 T>M No 1000Genomes
ENSVATH02783916 357 T>R No 1000Genomes
ENSVATH00489101 366 N>D No 1000Genomes
ENSVATH14131358 366 N>T No 1000Genomes
tmp_4_6761310_A_G 367 V>A No 1000Genomes
ENSVATH00489100 370 N>D No 1000Genomes
tmp_4_6761275_A_G 379 Y>H No 1000Genomes
ENSVATH14131357 386 A>V No 1000Genomes
ENSVATH06612834 393 E>G No 1000Genomes
ENSVATH06612833 396 G>A No 1000Genomes
tmp_4_6761135_G_T 400 S>* No 1000Genomes
ENSVATH00489094 400 S>A No 1000Genomes
ENSVATH11485849 404 A>T No 1000Genomes
ENSVATH00489091 407 S>T No 1000Genomes
ENSVATH11485846 423 S>C No 1000Genomes
ENSVATH11485845 423 S>N No 1000Genomes
ENSVATH00489086 427 E>A No 1000Genomes
ENSVATH06612831 427 E>K No 1000Genomes
ENSVATH11485784 431 A>D No 1000Genomes
ENSVATH02783903 432 Y>* No 1000Genomes
tmp_4_6760934_T_A 435 E>D No 1000Genomes
tmp_4_6760923_T_C 439 Y>C No 1000Genomes
ENSVATH06612830 440 N>K No 1000Genomes
ENSVATH06612829 443 K>* No 1000Genomes
ENSVATH02783902 444 T>A No 1000Genomes

No associated diseases with Q9T012

3 regional properties for Q9T012

Type Name Position InterPro Accession
domain High mobility group box domain 128 - 198 IPR009071-1
domain High mobility group box domain 245 - 313 IPR009071-2
domain High mobility group box domain 371 - 441 IPR009071-3

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q32L34 HMGB4 High mobility group protein B4 Bos taurus (Bovine) PR
Q0II87 TFAM Transcription factor A, mitochondrial Bos taurus (Bovine) PR
Q00059 TFAM Transcription factor A, mitochondrial Homo sapiens (Human) PR
P17480 UBTF Nucleolar transcription factor 1 Homo sapiens (Human) EV
P40630 Tfam Transcription factor A, mitochondrial Mus musculus (Mouse) PR
Q3USZ2 Ubtfl1 Upstream-binding factor 1-like protein 1 Mus musculus (Mouse) PR
P25976 Ubtf Nucleolar transcription factor 1 Mus musculus (Mouse) PR
Q5D144 TFAM Transcription factor A, mitochondrial Sus scrofa (Pig) PR
P25977 Ubtf Nucleolar transcription factor 1 Rattus norvegicus (Rat) PR
Q9SUP7 HMGB6 High mobility group B protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSTVSSDPAH AKKSRNSRKA LKQKNEIVES SPVSDKGKET KSFEKDLMEM QAMLEKMKIE
70 80 90 100 110 120
KEKTEDLLKE KDEILRKKEV EQEKLKTELK KLQKMKEFKP NMTFAFSQSL AQTEEEKKGK
130 140 150 160 170 180
KKKKDCAETK RPSTPYILWC KDNWNEVKKQ NPEADFKETS NILGAKWKGI SAEEKKPYEE
190 200 210 220 230 240
KYQADKEAYL QVITKEKRER EAMKLLDDEQ KQKTAMELLD QYLHFVQEAE HDNKKKAKKI
250 260 270 280 290 300
KDPLKPKQPI SAYLIYANER RAALKGENKS VIEVAKMAGE EWKNLSEEKK APYDQMAKKN
310 320 330 340 350 360
KEIYLQEMEG YKRTKEEEAM SQKKEEEEFM KLHKQEALQL LKKKEKTDNI IKKTKETAKN
370 380 390 400 410 420
KKKNENVDPN KPKKPTSSYF LFCKDARKSV LEEHPGINNS TVTAHISLKW MELGEEEKQV
430 440
YNSKAAELME AYKKEVEEYN KTKTSS