Q9SZI3

PR
Gene name
NPR2 (At4g26120, F20B18.230)
Protein name
Regulatory protein NPR2
Names
BTB/POZ domain-containing protein NPR2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G26120
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

522-594 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SZI3

Entry ID Method Resolution Chain Position Source
AF-Q9SZI3-F1 Predicted AlphaFoldDB

58 variants for Q9SZI3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_13236460_A_C 5 T>P No 1000Genomes
ENSVATH06777492 14 D>N No 1000Genomes
tmp_4_13236569_C_G 41 T>R No 1000Genomes
ENSVATH06777496 63 E>A No 1000Genomes
tmp_4_13236667_G_T 74 A>S No 1000Genomes
ENSVATH00538883 75 G>C No 1000Genomes
ENSVATH06777498 78 E>K No 1000Genomes
ENSVATH06777499 80 S>T No 1000Genomes
ENSVATH00538884 81 F>C No 1000Genomes
ENSVATH12233627 84 C>Y No 1000Genomes
ENSVATH12233628 91 P>S No 1000Genomes
ENSVATH06777500 102 E>K No 1000Genomes
tmp_4_13236764_C_T 106 S>F No 1000Genomes
ENSVATH06777502 123 G>S No 1000Genomes
tmp_4_13236829_G_T 128 V>L No 1000Genomes
tmp_4_13236883_G_A 146 A>T No 1000Genomes
ENSVATH00538886 161 S>P No 1000Genomes
tmp_4_13237099_C_A 194 D>E No 1000Genomes
ENSVATH06777511 199 E>K No 1000Genomes
ENSVATH06777512 208 D>E No 1000Genomes
ENSVATH06777513 213 T>K No 1000Genomes
tmp_4_13237174_G_C 219 L>F No 1000Genomes
ENSVATH00538888 231 I>L No 1000Genomes
tmp_4_13237220_A_T 235 S>C No 1000Genomes
ENSVATH12233633 271 K>Q No 1000Genomes
tmp_4_13237358_G_A 281 V>I No 1000Genomes
tmp_4_13237445_G_T 310 A>S No 1000Genomes
tmp_4_13237446_C_T 310 A>V No 1000Genomes
tmp_4_13237449_A_C 311 Y>S No 1000Genomes
ENSVATH00538889 312 D>N No 1000Genomes
ENSVATH02925105 355 L>I No 1000Genomes
ENSVATH06777519 358 T>K No 1000Genomes
ENSVATH06777521 367 I>T No 1000Genomes
ENSVATH14297298 369 K>E No 1000Genomes
ENSVATH00538890 374 A>V No 1000Genomes
ENSVATH06777522 380 S>G No 1000Genomes
tmp_4_13237659_C_T 381 T>M No 1000Genomes
ENSVATH00538891 394 I>M No 1000Genomes
ENSVATH12233705 403 L>I No 1000Genomes
ENSVATH00538892 406 L>V No 1000Genomes
ENSVATH08367334 412 S>L No 1000Genomes
ENSVATH06777526 450 I>L No 1000Genomes
tmp_4_13237987_C_T 462 S>F No 1000Genomes
ENSVATH12233706 464 L>F No 1000Genomes
tmp_4_13238013_G_A 471 G>S No 1000Genomes
ENSVATH06777528 495 R>K No 1000Genomes
tmp_4_13238217_T_G 511 C>W No 1000Genomes
tmp_4_13238254_C_T 524 H>Y No 1000Genomes
ENSVATH06777536 528 V>I No 1000Genomes
ENSVATH02925106 540 K>N No 1000Genomes
ENSVATH06777537 555 S>I No 1000Genomes
ENSVATH06777538 566 T>A No 1000Genomes
tmp_4_13238384_C_T 567 P>L No 1000Genomes
ENSVATH06777539 572 A>S No 1000Genomes
tmp_4_13238432_G_C 583 R>P No 1000Genomes
tmp_4_13238443_G_A 587 D>N No 1000Genomes
ENSVATH12233709 596 Y>N No 1000Genomes
ENSVATH06777541 599 G>V No 1000Genomes

No associated diseases with Q9SZI3

2 regional properties for Q9SZI3

Type Name Position InterPro Accession
domain Rho GTPase-activating protein domain 244 - 431 IPR000198
domain CRAL-TRIO lipid binding domain 63 - 218 IPR001251

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

6 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
defense response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
regulation of jasmonic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.
regulation of salicylic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.
systemic acquired resistance, salicylic acid mediated signaling pathway The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.

14 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q04861 NFKB1 Nuclear factor NF-kappa-B p105 subunit Gallus gallus (Chicken) SS
P98150 NFKB2 Nuclear factor NF-kappa-B p100 subunit Gallus gallus (Chicken) SS
Q94527 Rel Nuclear factor NF-kappa-B p110 subunit Drosophila melanogaster (Fruit fly) EV
P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit Homo sapiens (Human) SS
Q99549 MPHOSPH8 M-phase phosphoprotein 8 Homo sapiens (Human) PR
Q00653 NFKB2 Nuclear factor NF-kappa-B p100 subunit Homo sapiens (Human) SS
Q8N9B4 ANKRD42 Ankyrin repeat domain-containing protein 42 Homo sapiens (Human) PR
Q6ZVZ8 ASB18 Ankyrin repeat and SOCS box protein 18 Homo sapiens (Human) PR
Q9CZK6 Anks3 Ankyrin repeat and SAM domain-containing protein 3 Mus musculus (Mouse) PR
P25799 Nfkb1 Nuclear factor NF-kappa-B p105 subunit [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] Mus musculus (Mouse) EV
Q8VHA6 Asb18 Ankyrin repeat and SOCS box protein 18 Mus musculus (Mouse) PR
Q9WTK5 Nfkb2 Nuclear factor NF-kappa-B p100 subunit [Cleaved into: Nuclear factor NF-kappa-B p52 subunit] Mus musculus (Mouse) EV
Q9TZM3 lrk-1 Leucine-rich repeat serine/threonine-protein kinase 1 Caenorhabditis elegans SS
O22265 CAO Signal recognition particle 43 kDa protein, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATTTTTTTA RFSDSYEFSN TSGNSFFAAE SSLDYPTEFL TPPEVSALKL LSNCLESVFD
70 80 90 100 110 120
SPETFYSDAK LVLAGGREVS FHRCILSARI PVFKSALATV KEQKSSTTVK LQLKEIARDY
130 140 150 160 170 180
EVGFDSVVAV LAYVYSGRVR SPPKGASACV DDDCCHVACR SKVDFMVEVL YLSFVFQIQE
190 200 210 220 230 240
LVTLYERQFL EIVDKVVVED ILVIFKLDTL CGTTYKKLLD RCIEIIVKSD IELVSLEKSL
250 260 270 280 290 300
PQHIFKQIID IREALCLEPP KLERHVKNIY KALDSDDVEL VKMLLLEGHT NLDEAYALHF
310 320 330 340 350 360
AIAHCAVKTA YDLLELELAD VNLRNPRGYT VLHVAAMRKE PKLIISLLMK GANILDTTLD
370 380 390 400 410 420
GRTALVIVKR LTKADDYKTS TEDGTPSLKG GLCIEVLEHE QKLEYLSPIE ASLSLPVTPE
430 440 450 460 470 480
ELRMRLLYYE NRVALARLLF PVETETVQGI AKLEETCEFT ASSLEPDHHI GEKRTSLDLN
490 500 510 520 530 540
MAPFQIHEKH LSRLRALCKT VELGKRYFKR CSLDHFMDTE DLNHLASVEE DTPEKRLQKK
550 560 570 580 590
QRYMELQETL MKTFSEDKEE CGKSSTPKPT SAVRSNRKLS HRRLKVDKRD FLKRPYGNGD