Q9STF0

PR
Gene name
LECRKS3 (At3g46760, T6H20.210)
Protein name
Receptor like protein kinase S.3
Names
LecRK-S.3
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G46760
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-75 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9STF0

Entry ID Method Resolution Chain Position Source
AF-Q9STF0-F1 Predicted AlphaFoldDB

21 variants for Q9STF0

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14385899 11 A>V No 1000Genomes
ENSVATH06251592 31 E>Q No 1000Genomes
ENSVATH06251594 58 T>K No 1000Genomes
ENSVATH06251595 66 K>N No 1000Genomes
tmp_3_17222273_G_A 83 D>N No 1000Genomes
tmp_3_17222370_G_T 115 R>I No 1000Genomes
ENSVATH14385900 127 P>R No 1000Genomes
tmp_3_17222563_G_C 179 L>F No 1000Genomes
tmp_3_17222608_T_A 194 F>L No 1000Genomes
tmp_3_17222651_G_T 209 A>S No 1000Genomes
ENSVATH00403707 221 K>R No 1000Genomes
ENSVATH12581998 235 A>T No 1000Genomes
tmp_3_17222756_C_T 244 P>S No 1000Genomes
ENSVATH14385901 257 C>Y No 1000Genomes
tmp_3_17222822_G_A 266 V>I No 1000Genomes
ENSVATH02454423 268 A>G No 1000Genomes
ENSVATH02454422 268 A>T No 1000Genomes
ENSVATH00403709 279 C>G No 1000Genomes
ENSVATH00403709 279 C>S No 1000Genomes
tmp_3_17223012_C_T 329 P>L No 1000Genomes
ENSVATH00403711 333 H>N No 1000Genomes

No associated diseases with Q9STF0

3 regional properties for Q9STF0

Type Name Position InterPro Accession
domain Protein kinase domain 50 - 316 IPR000719
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 54 - 310 IPR001245
active_site Serine/threonine-protein kinase, active site 167 - 179 IPR008271

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

3 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
defense response to oomycetes Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
protein phosphorylation The process of introducing a phosphate group on to a protein.

34 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q05688 IGF1R Insulin-like growth factor 1 receptor Bos taurus (Bovine) SS
Q9Y616 IRAK3 Interleukin-1 receptor-associated kinase 3 Homo sapiens (Human) PR
P53667 LIMK1 LIM domain kinase 1 Homo sapiens (Human) PR
P53671 LIMK2 LIM domain kinase 2 Homo sapiens (Human) PR
Q8K4B2 Irak3 Interleukin-1 receptor-associated kinase 3 Mus musculus (Mouse) PR
Q8CFA1 Irak2 Interleukin-1 receptor-associated kinase-like 2 Mus musculus (Mouse) PR
O54785 Limk2 LIM domain kinase 2 Mus musculus (Mouse) PR
Q4QQS0 Irak2 Interleukin-1 receptor-associated kinase-like 2 Rattus norvegicus (Rat) PR
Q9ASQ5 CRCK3 Calmodulin-binding receptor-like cytoplasmic kinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LPS5 SERK5 Somatic embryogenesis receptor kinase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RWW0 ALE2 Receptor-like serine/threonine-protein kinase ALE2 Arabidopsis thaliana (Mouse-ear cress) PR
P93050 BSH Probable LRR receptor-like serine/threonine-protein kinase RKF3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRP3 At3g17420 Probable receptor-like protein kinase At3g17420 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSV3 WAKL16 Putative wall-associated receptor kinase-like 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCZ4 FER Receptor-like protein kinase FERONIA Arabidopsis thaliana (Mouse-ear cress) PR
Q9M342 WAKL15 Wall-associated receptor kinase-like 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LYN6 At3g56050 Probable inactive receptor-like protein kinase At3g56050 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZJ9 CRCK2 Calmodulin-binding receptor-like cytoplasmic kinase 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q0WNY5 WAKL18 Wall-associated receptor kinase-like 18 Arabidopsis thaliana (Mouse-ear cress) PR
P43293 PBL11 Probable serine/threonine-protein kinase PBL11 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C25 At5g20050 Probable receptor-like protein kinase At5g20050 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FLW0 At5g24010 Probable receptor-like protein kinase At5g24010 Arabidopsis thaliana (Mouse-ear cress) PR
Q3E8W4 ANX2 Receptor-like protein kinase ANXUR2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTC0 PBL19 Probable serine/threonine-protein kinase PBL19 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIL7 CRCK1 Calmodulin-binding receptor-like cytoplasmic kinase 1 Arabidopsis thaliana (Mouse-ear cress) PR
O80939 LECRK41 L-type lectin-domain containing receptor kinase IV.1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M1G4 LECRK15 Probable L-type lectin-domain containing receptor kinase I.5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M345 LECRK42 L-type lectin-domain containing receptor kinase IV.2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2S4 LECRKS4 L-type lectin-domain containing receptor kinase S.4 Arabidopsis thaliana (Mouse-ear cress) PR
Q96285 LECRK55 L-type lectin-domain containing receptor kinase V.5 Arabidopsis thaliana (Mouse-ear cress) PR
O81292 LECRK43 L-type lectin-domain containing receptor kinase IV.3 Arabidopsis thaliana (Mouse-ear cress) PR
O81291 LECRK44 L-type lectin-domain containing receptor kinase IV.4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FG33 LECRKS5 Probable L-type lectin-domain containing receptor kinase S.5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSR8 LECRK19 L-type lectin-domain containing receptor kinase I.9 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFAGIFLRMG AALRSMYVNS KYEEVREEWE EDYSPQRFSY KALYKATKGF KESELFGTEA
70 80 90 100 110 120
NGTVYKGKLS SNAQIAVKRV SLDAEQDTKH LVSQIVGIGK LRHKNLVQLL GYCRRKGELL
130 140 150 160 170 180
LVYDYMPYGN LDDFLFNEER PNLSWSQRFH IIKGVASALL YLHEQIVLHR DVKAANVLLD
190 200 210 220 230 240
EDLNGRLDYG LARFGTNRNP MLGSVGYVAP ELIITGMPTT KADVYSFGAL LLEFACGRMF
250 260 270 280 290 300
IEYPGKPEEF NLISWVCQCW KRGNLVGARD ARLEGDYVCK EIEMVLKLGL LCAQYNPEDR
310 320 330
PSMSQVVNYL EGNDVLPEMP PDTPGISIPT PYHEVLA