Q9SSM4
Gene name |
CHMP1B |
Protein name |
ESCRT-related protein CHMP1B |
Names |
Protein CHARGED MULTIVESICULAR BODY PROTEIN 1B, Protein CHROMATIN MODIFYING PROTEIN 1B, Vacuolar protein-sorting-associated protein 46.2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G73030 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SSM4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SSM4-F1 | Predicted | AlphaFoldDB |
4 variants for Q9SSM4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_27474033_G_T | 32 | E>D | No | 1000Genomes | |
| ENSVATH05135556 | 80 | A>D | No | 1000Genomes | |
| ENSVATH13800087 | 95 | M>L | No | 1000Genomes | |
| ENSVATH05135562 | 153 | N>S | No | 1000Genomes |
No associated diseases with Q9SSM4
No regional properties for Q9SSM4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SSM4 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| ESCRT III complex | A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission). |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| multivesicular body | A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| embryo development ending in seed dormancy | The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana. |
| embryonic axis specification | The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. |
| endosome transport via multivesicular body sorting pathway | The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment. |
| late endosome to vacuole transport | The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| seedling development | The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5E994 | CHMP1B | Charged multivesicular body protein 1b | Bos taurus (Bovine) | PR |
| Q5ZKX1 | CHMP1B | Charged multivesicular body protein 1b | Gallus gallus (Chicken) | PR |
| Q7LBR1 | CHMP1B | Charged multivesicular body protein 1b | Homo sapiens (Human) | PR |
| Q9CQD4 | Chmp1b2 | Charged multivesicular body protein 1b-2 | Mus musculus (Mouse) | PR |
| Q99LU0 | Chmp1b1 | Charged multivesicular body protein 1b-1 | Mus musculus (Mouse) | PR |
| Q84VG1 | CHMP1 | ESCRT-related protein CHMP1 | Oryza sativa subsp japonica (Rice) | PR |
| Q8LE58 | CHMP1A | ESCRT-related protein CHMP1A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKI2 | VPS2.1 | Vacuolar protein sorting-associated protein 2 homolog 1 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q6DF27 | chmp1b | Charged multivesicular body protein 1b | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q7ZVB1 | chmp1b | Charged multivesicular body protein 1b | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGNTDKLMNQ | IFDLKFTSKS | LQRQSRKCEK | EEKAEKLKVK | KAIEKGNMDG | ARIYAENAIR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KRSEQMNYLR | LASRLDAVVA | RLDTQAKMTT | ITKSMTNIVK | SLESSLATGN | LQKMSETMDS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FEKQFVNMEV | QAEFMENAMA | GSTSLSTPEG | EVNSLMQQVA | DDYGLEVSVG | LPQPAGHAIP |
| 190 | 200 | ||||
| TKTEEKVDED | DLSRRLAELK | ARG |