Q9SKX0
PR
Gene name |
ABCC13 (MRP11, MRP13, At2g07680, T5E7.1) |
Protein name |
ABC transporter C family member 13 |
Names |
ABC transporter ABCC.13, AtABCC13, ATP-energized glutathione S-conjugate pump 11, Glutathione S-conjugate-transporting ATPase 11, Multidrug resistance-associated protein 11 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G07680 |
EC number |
7.6.2.2: Linked to the hydrolysis of a nucleoside triphosphate |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SKX0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SKX0-F1 | Predicted | AlphaFoldDB |
No variants for Q9SKX0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9SKX0 | |||||
No associated diseases with Q9SKX0
Functions
| Description | ||
|---|---|---|
| EC Number | 7.6.2.2 | Linked to the hydrolysis of a nucleoside triphosphate |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type xenobiotic transporter activity | Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled transmembrane transporter activity | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
24 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8HXQ5 | ABCC1 | Multidrug resistance-associated protein 1 | Bos taurus (Bovine) | PR |
| Q2QLE5 | CFTR | Cystic fibrosis transmembrane conductance regulator | Pan troglodytes (Chimpanzee) | PR |
| P91660 | Rh5 | Probable multidrug resistance-associated protein lethal(2)03659 | Drosophila melanogaster (Fruit fly) | PR |
| P13569 | CFTR | Cystic fibrosis transmembrane conductance regulator | Homo sapiens (Human) | PR |
| O95255 | ABCC6 | ATP-binding cassette sub-family C member 6 | Homo sapiens (Human) | PR |
| O15438 | ABCC3 | ATP-binding cassette sub-family C member 3 | Homo sapiens (Human) | PR |
| Q92887 | ABCC2 | ATP-binding cassette sub-family C member 2 | Homo sapiens (Human) | SS |
| O15439 | ABCC4 | ATP-binding cassette sub-family C member 4 | Homo sapiens (Human) | PR |
| Q96J66 | ABCC11 | ATP-binding cassette sub-family C member 11 | Homo sapiens (Human) | PR |
| P33527 | ABCC1 | Multidrug resistance-associated protein 1 | Homo sapiens (Human) | PR |
| B2RX12 | Abcc3 | ATP-binding cassette sub-family C member 3 | Mus musculus (Mouse) | PR |
| Q8VI47 | Abcc2 | ATP-binding cassette sub-family C member 2 | Mus musculus (Mouse) | SS |
| P26361 | Cftr | Cystic fibrosis transmembrane conductance regulator | Mus musculus (Mouse) | PR |
| O35379 | Abcc1 | Multidrug resistance-associated protein 1 | Mus musculus (Mouse) | PR |
| Q80WJ6 | Abcc12 | ATP-binding cassette sub-family C member 12 | Mus musculus (Mouse) | PR |
| Q6PQZ2 | CFTR | Cystic fibrosis transmembrane conductance regulator | Sus scrofa (Pig) | PR |
| Q6Y306 | Abcc12 | ATP-binding cassette sub-family C member 12 | Rattus norvegicus (Rat) | PR |
| Q8CG09 | Abcc1 | Multidrug resistance-associated protein 1 | Rattus norvegicus (Rat) | PR |
| Q63120 | Abcc2 | ATP-binding cassette sub-family C member 2 | Rattus norvegicus (Rat) | EV |
| Q00553 | CFTR | Cystic fibrosis transmembrane conductance regulator | Macaca mulatta (Rhesus macaque) | PR |
| Q8VZZ4 | ABCC6 | ABC transporter C family member 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C8G9 | ABCC1 | ABC transporter C family member 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C8H0 | ABCC12 | ABC transporter C family member 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M1C7 | ABCC9 | ABC transporter C family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAITLTNFTF | LYMDANLKRL | GDIVLGFGAN | VVTLLLILIL | TITRRNGRCN | RRKSYIEKCL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LYVTPALGAC | LSCVDLVLLV | RTNRRREVIL | CFVPLSGFVM | WIAVILSLKF | ACCACHVFTS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QILCFWWIFR | FLTDALHLNM | IFTLQRVQEI | CLIMLDIAFG | ISINVLRIKQ | AHPKIIPLED |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PLIEDDDDQK | RIVRRLFLEK | NGSWWDLFTF | GYIGSIMKHG | SVKQLELENL | LTLPPEMDPF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TCCENLLRCW | QLQECNNYST | PSLIWSIYGV | YGWPYFRLGL | LKVFNDCIGF | AGPLLLNRLI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KSFLDTQYTF | RLSKLKLKLR | SSIMSVIYRK | CLWVNTANRS | GFSEGEIQTF | MSVDADRIVN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LCNSLHDLWS | LPLQIGIALY | LLYTQVKFAF | LSGLAITILL | IPVNKWISVL | IASATEKMMK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LKDERIRKTG | ELLTNIRTLK | MYGWDNWFAD | WLKETRATEV | THLATRKYLD | AWCVFFWATT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PTLFSLCTFG | LFALMGHQLD | AATVFTCLAL | FNSLISPLNS | FPWVINGLID | AFISTRRVSK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FLCCLEHSRD | FSIDSGFTSE | DLAVCVEDAS | CTWSSNVEED | YNLTIKQVSL | RVPKGSFVAV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IGEVGSGKTS | LLNSLLGEMR | CVHGSILLNG | SVAYVPQVPW | LLSGTVRENI | LFGKPFDSKR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| YFETLSACAL | DVDISLMVGG | DMACIGDKGL | NLSGGQRARF | ALARAVYHGS | DMYLLDDVLS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| AVDSQVGCWI | LQRALLGPLL | NKKTRVMCTH | NIQAISCADM | IVVMDKGKVN | WSGSVTDMPK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| SISPTFSLTN | EFDMSSPNHL | TKRKETLSIK | EDGVDEISEA | AADIVKLEER | KEGRVEMMVY |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RNYAVFSGWF | ITIVILVSAV | LMQGSRNGND | LWLSYWVDKT | GKGVSHYSTS | FYLMVLCIFC |
| 910 | 920 | 930 | 940 | 950 | 960 |
| IINSILTLVR | AFSFAFGGLK | AAVHVHNALI | SKLINAPTQF | FDQTPSGRIL | NRFSSDLYTI |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| DDSLPFILNI | LLANFVGLLG | IIVVLSYVQV | LFLLLLLPFW | YIYSKLQVFY | RSTSRELRRL |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| DSVSRSPIYA | SFTETLDGSS | TIRAFKSEEH | FVGRFIEHLT | LYQRTSYSEI | IASLWLSLRL |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| QLLGSMIVLF | VAVMAVLGSG | GNFPISFGTP | GLVGLALSYA | APLVSLLGSL | LTSFTETEKE |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| MVSVERVLQY | MDVPQEEVSG | PQSLSDKWPV | HGLVEFHNVT | MRYISTLPPA | LTQISFTIQG |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| GMHVGVIGRT | GAGKSSILNA | LFRLTPVCSG | EILVDGKNIS | HLPIRELRSC | LAVVPQSPFL |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| FQGSLRDNLD | PLGLSEDWRI | WEILDKCKVK | AAVESVGGLD | SYVKESGCSF | SVGQRQLLCL |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| ARALLKSSKI | LCLDECTANI | DVHTASLLHN | TISSECKGVT | VITIAHRIST | VVDLDSILIL |
| 1390 | 1400 | ||||
| DRGILVEQGK | PQHLLQDDSS | TFSSFVRASQ |