Q9SKK8

PR
Gene name
ATL22 (At2g25410, F13B15.7)
Protein name
RING-H2 finger protein ATL22
Names
RING-type E3 ubiquitin transferase ATL22
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G25410
EC number
2.3.2.27: Aminoacyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

237-349 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SKK8

Entry ID Method Resolution Chain Position Source
AF-Q9SKK8-F1 Predicted AlphaFoldDB

126 variants for Q9SKK8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01893352 5 L>Q No 1000Genomes
ENSVATH05588656 6 L>F No 1000Genomes
tmp_2_10814494_C_T 9 L>F No 1000Genomes
ENSVATH01893353 10 L>F No 1000Genomes
ENSVATH01893354 11 N>H No 1000Genomes
ENSVATH14551074 17 F>L No 1000Genomes
ENSVATH05588657 19 P>L No 1000Genomes
ENSVATH14551085 20 L>F No 1000Genomes
tmp_2_10814534_A_G 22 N>S No 1000Genomes
ENSVATH05588659 24 S>F No 1000Genomes
ENSVATH01893357 26 Q>* No 1000Genomes
ENSVATH01893358 26 Q>P No 1000Genomes
tmp_2_10814552_C_T 28 P>L No 1000Genomes
ENSVATH14551087 31 S>C No 1000Genomes
tmp_2_10814561_G_A 31 S>N No 1000Genomes
ENSVATH13398791 34 C>Y No 1000Genomes
ENSVATH01893360 37 E>* No 1000Genomes
ENSVATH01893361 37 E>G No 1000Genomes
tmp_2_10814584_G_A 39 V>I No 1000Genomes
ENSVATH00246729 41 A>V No 1000Genomes
ENSVATH13398792 44 P>S No 1000Genomes
ENSVATH05588660 49 S>P No 1000Genomes
ENSVATH05588661 52 P>L No 1000Genomes
ENSVATH14551088 55 C>Y No 1000Genomes
tmp_2_10814644_G_A 59 G>R No 1000Genomes
tmp_2_10814653_C_T 62 L>F No 1000Genomes
ENSVATH01893366 63 I>L No 1000Genomes
ENSVATH00246732 65 K>T No 1000Genomes
ENSVATH01893367 67 D>G No 1000Genomes
ENSVATH13398794 67 D>N No 1000Genomes
ENSVATH05588662 68 A>V No 1000Genomes
ENSVATH00246733 71 T>A No 1000Genomes
ENSVATH01893368 73 K>M No 1000Genomes
tmp_2_10814686_A_C 73 K>Q No 1000Genomes
ENSVATH05588663 75 P>L No 1000Genomes
ENSVATH00246734 77 S>T No 1000Genomes
ENSVATH05588664 78 E>K No 1000Genomes
ENSVATH00246735 81 L>V No 1000Genomes
ENSVATH01893370 83 K>R No 1000Genomes
ENSVATH05588666 88 E>K No 1000Genomes
tmp_2_10814734_A_T 89 T>S No 1000Genomes
ENSVATH13398809 91 R>H No 1000Genomes
ENSVATH13398810 93 R>C No 1000Genomes
ENSVATH13398811 96 D>N No 1000Genomes
ENSVATH05588668 97 P>T No 1000Genomes
tmp_2_10814761_G_A 98 E>K No 1000Genomes
tmp_2_10814774_C_T 102 A>V No 1000Genomes
ENSVATH01893376 103 R>K No 1000Genomes
tmp_2_10814788_A_G 107 N>D No 1000Genomes
tmp_2_10814794_G_C 109 D>H No 1000Genomes
tmp_2_10814798_C_G 110 P>R No 1000Genomes
tmp_2_10814801_C_T 111 S>L No 1000Genomes
ENSVATH05588671 112 G>R No 1000Genomes
ENSVATH05588672 114 P>H No 1000Genomes
ENSVATH05588672 114 P>L No 1000Genomes
ENSVATH01893378 114 P>S No 1000Genomes
ENSVATH01893379 117 F>L No 1000Genomes
ENSVATH01893380 117 F>S No 1000Genomes
ENSVATH05588673 118 L>F No 1000Genomes
ENSVATH05588674 119 R>C No 1000Genomes
ENSVATH05588675 119 R>P No 1000Genomes
tmp_2_10814847_G_T 126 L>F No 1000Genomes
ENSVATH00246738 129 P>H No 1000Genomes
ENSVATH00246739 131 E>V No 1000Genomes
tmp_2_10814863_G_T 132 A>S No 1000Genomes
ENSVATH01893384 134 I>V No 1000Genomes
ENSVATH13398812 135 T>I No 1000Genomes
ENSVATH13398812 135 T>N No 1000Genomes
tmp_2_10814875_G_T 136 A>S No 1000Genomes
ENSVATH01893385 142 D>N No 1000Genomes
ENSVATH05588677 144 L>I No 1000Genomes
ENSVATH05588678 145 G>D No 1000Genomes
ENSVATH00246742 147 T>S No 1000Genomes
ENSVATH05588680 155 Q>H No 1000Genomes
ENSVATH00246744 160 G>V No 1000Genomes
ENSVATH05588681 161 S>L No 1000Genomes
tmp_2_10814957_C_T 163 P>L No 1000Genomes
ENSVATH01893386 171 I>T No 1000Genomes
tmp_2_10814998_T_C 177 S>P No 1000Genomes
ENSVATH00246746 179 F>Y No 1000Genomes
ENSVATH13398813 183 T>A No 1000Genomes
tmp_2_10815017_C_T 183 T>M No 1000Genomes
ENSVATH01893387 184 T>A No 1000Genomes
ENSVATH01893388 185 Y>F No 1000Genomes
ENSVATH01893389 187 D>G No 1000Genomes
tmp_2_10815032_G_A 188 G>D No 1000Genomes
tmp_2_10815038_A_G 190 N>S No 1000Genomes
tmp_2_10815043_C_T 192 R>* No 1000Genomes
tmp_2_10815044_G_A 192 R>Q No 1000Genomes
ENSVATH01893390 194 M>L No 1000Genomes
tmp_2_10815068_C_T 200 S>L No 1000Genomes
tmp_2_10815071_C_T 201 P>L No 1000Genomes
ENSVATH05588682 204 R>K No 1000Genomes
tmp_2_10815095_G_A,T 209 R>I No 1000Genomes
tmp_2_10815095_G_A,T 209 R>K No 1000Genomes
tmp_2_10815097_A_G 210 T>A No 1000Genomes
tmp_2_10815098_C_T 210 T>I No 1000Genomes
ENSVATH05588683 225 E>K No 1000Genomes
tmp_2_10815155_C_A 229 S>Y No 1000Genomes
ENSVATH13398845 230 V>A No 1000Genomes
tmp_2_10815157_G_A 230 V>I No 1000Genomes
tmp_2_10815161_A_G 231 N>S No 1000Genomes
ENSVATH13398846 232 P>L No 1000Genomes
tmp_2_10815163_C_T 232 P>S No 1000Genomes
ENSVATH05588684 233 G>R No 1000Genomes
ENSVATH00246755 245 M>I No 1000Genomes
ENSVATH01893405 256 L>M No 1000Genomes
tmp_2_10815570_G_C 263 V>L No 1000Genomes
ENSVATH05588694 269 R>S No 1000Genomes
ENSVATH13398870 273 Q>H No 1000Genomes
ENSVATH01893406 276 Q>H No 1000Genomes
tmp_2_10815615_G_A 278 V>M No 1000Genomes
tmp_2_10815621_G_A 280 A>T No 1000Genomes
tmp_2_10815651_C_T 290 P>S No 1000Genomes
tmp_2_10815658_A_T 292 N>I No 1000Genomes
tmp_2_10815664_T_G 294 V>G No 1000Genomes
ENSVATH00246756 297 I>M No 1000Genomes
tmp_2_10815681_G_A 300 D>N No 1000Genomes
ENSVATH01893407 309 K>R No 1000Genomes
tmp_2_10815753_G_A 324 D>N No 1000Genomes
ENSVATH05588695 336 T>I No 1000Genomes
tmp_2_10815825_C_A 348 H>N No 1000Genomes
tmp_2_10815832_T_A 350 F>Y No 1000Genomes
tmp_2_10815834_C_G 351 H>D No 1000Genomes
tmp_2_10815891_A_G 370 S>G No 1000Genomes
tmp_2_10815915_T_C 378 D>R No 1000Genomes

No associated diseases with Q9SKK8

3 regional properties for Q9SKK8

Type Name Position InterPro Accession
domain Protein kinase domain 20 - 312 IPR000719
active_site Serine/threonine-protein kinase, active site 145 - 157 IPR008271
binding_site Protein kinase, ATP binding site 26 - 50 IPR017441

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
polysaccharide binding Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

1 GO annotations of biological process

Name Definition
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VE61 CG7694 E3 ubiquitin-protein ligase RNF181 homolog Drosophila melanogaster (Fruit fly) PR
O00237 RNF103 E3 ubiquitin-protein ligase RNF103 Homo sapiens (Human) PR
Q86Y13 DZIP3 E3 ubiquitin-protein ligase DZIP3 Homo sapiens (Human) PR
Q9Y3E7 CHMP3 Charged multivesicular body protein 3 Homo sapiens (Human) EV
Q9R1W3 Rnf103 E3 ubiquitin-protein ligase RNF103 Mus musculus (Mouse) PR
Q9EPZ8 Rnf103 E3 ubiquitin-protein ligase RNF103 Rattus norvegicus (Rat) PR
Q9SI09 XERICO Probable E3 ubiquitin-protein ligase XERICO Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZV51 ATL56 RING-H2 finger protein ATL56 Arabidopsis thaliana (Mouse-ear cress) PR
O22255 ATL64 RING-H2 finger protein ATL64 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RXX9 ATL6 E3 ubiquitin-protein ligase ATL6 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYT9 SIS3 E3 ubiquitin-protein ligase SIS3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZJ6 ATL5 RING-H2 finger protein ATL5 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXF8 SGR9 E3 ubiquitin-protein ligase SGR9, amyloplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q8LGA5 ATL31 E3 ubiquitin-protein ligase ATL31 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUZ9 ATL63 RING-H2 finger protein ATL63 Arabidopsis thaliana (Mouse-ear cress) PR
P0CH01 ATL21A Putative RING-H2 finger protein ATL21A Arabidopsis thaliana (Mouse-ear cress) PR
P0CH02 ATL21B Putative RING-H2 finger protein ATL21B Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MTSKLLPLLL NLIFLFFFPL LNASEQKPCY SFSCSQESVV ARFPFSLFSY QPESCGYSGF
70 80 90 100 110 120
NLICKDDANT TLKLPKSEPF LVKEIDYETQ RIRLNDPENC LARRLLNFDP SGSPFSFLRS
130 140 150 160 170 180
RNYTFLICPK EANITASFRA IDCLGNTTSS FFVVQFENLG SMPSSCHIFK ILPLPFSWFV
190 200 210 220 230 240
AYTTYPDGQN SRDMWLKWDS PDCRDCERRT NSRCGFKNNT SHQVECFSSV NPGLHNTGLQ
250 260 270 280 290 300
VLKIMCLSLV GPLTALTFCV GLVMCSSERV SSQIQQAVVA RLSGSVTSQP SNEVARIGLD
310 320 330 340 350 360
ESTIESYKKV ELGESRRLPT GSNDVVCPIC LSEYATKETV RCLPECEHCF HTECIDAWLK
370
LHSSCPVCRS NPSPLRD