Q9SA27
PR
Gene name |
RH36 (At1g16280, F3O9.8) |
Protein name |
DEAD-box ATP-dependent RNA helicase 36 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G16280 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SA27
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SA27-F1 | Predicted | AlphaFoldDB |
34 variants for Q9SA27
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04585240 | 3 | E>Q | No | 1000Genomes | |
| ENSVATH04585239 | 6 | P>S | No | 1000Genomes | |
| ENSVATH04585238 | 9 | E>D | No | 1000Genomes | |
| ENSVATH00026486 | 16 | S>A | No | 1000Genomes | |
| ENSVATH04585237 | 30 | S>F | No | 1000Genomes | |
| ENSVATH04585236 | 31 | Q>L | No | 1000Genomes | |
| ENSVATH00026484 | 39 | T>A | No | 1000Genomes | |
| tmp_1_5570349_T_C | 47 | N>D | No | 1000Genomes | |
| tmp_1_5570337_T_G | 51 | S>R | No | 1000Genomes | |
| ENSVATH13905672 | 54 | T>A | No | 1000Genomes | |
| tmp_1_5570321_G_T | 56 | S>Y | No | 1000Genomes | |
| tmp_1_5570318_G_A | 57 | A>V | No | 1000Genomes | |
| ENSVATH04585232 | 58 | T>A | No | 1000Genomes | |
| ENSVATH04585231 | 58 | T>I | No | 1000Genomes | |
| tmp_1_5570298_C_T | 64 | G>R | No | 1000Genomes | |
| ENSVATH04585229 | 93 | L>F | No | 1000Genomes | |
| tmp_1_5570207_G_C | 94 | A>G | No | 1000Genomes | |
| ENSVATH04585224 | 129 | A>S | No | 1000Genomes | |
| tmp_1_5570028_T_G | 154 | N>H | No | 1000Genomes | |
| ENSVATH04585223 | 158 | S>T | No | 1000Genomes | |
| ENSVATH04585221 | 171 | M>I | No | 1000Genomes | |
| tmp_1_5569964_G_A | 175 | S>L | No | 1000Genomes | |
| ENSVATH11322227 | 230 | C>S | No | 1000Genomes | |
| ENSVATH04585215 | 258 | K>R | No | 1000Genomes | |
| ENSVATH04585213 | 306 | M>I | No | 1000Genomes | |
| tmp_1_5569477_C_A | 309 | V>F | No | 1000Genomes | |
| tmp_1_5569465_T_C | 313 | R>G | No | 1000Genomes | |
| ENSVATH00026480 | 351 | G>R | No | 1000Genomes | |
| tmp_1_5569261_G_A | 354 | P>L | No | 1000Genomes | |
| tmp_1_5569180_C_A | 381 | R>I | No | 1000Genomes | |
| ENSVATH11322022 | 438 | E>D | No | 1000Genomes | |
| ENSVATH13905671 | 439 | V>I | No | 1000Genomes | |
| ENSVATH01058163 | 483 | G>S | No | 1000Genomes | |
| ENSVATH11322019 | 490 | E>K | No | 1000Genomes |
No associated diseases with Q9SA27
5 regional properties for Q9SA27
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 208 - 216 | IPR000629 |
| domain | Helicase, C-terminal | 289 - 438 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 82 - 250 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 77 - 277 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 58 - 86 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| pollen tube | A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| nucleic acid binding | Binding to a nucleic acid. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| embryo sac development | The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate. |
| megagametogenesis | The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. |
| post-embryonic development | The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
23 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P53166 | MRH4 | ATP-dependent RNA helicase MRH4, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P15424 | MSS116 | ATP-dependent RNA helicase MSS116, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q29S22 | DDX47 | Probable ATP-dependent RNA helicase DDX47 | Bos taurus (Bovine) | PR |
| Q9Y6V7 | DDX49 | Probable ATP-dependent RNA helicase DDX49 | Homo sapiens (Human) | PR |
| Q9H0S4 | DDX47 | Probable ATP-dependent RNA helicase DDX47 | Homo sapiens (Human) | PR |
| Q4FZF3 | Ddx49 | Probable ATP-dependent RNA helicase DDX49 | Mus musculus (Mouse) | PR |
| Q9CWX9 | Ddx47 | Probable ATP-dependent RNA helicase DDX47 | Mus musculus (Mouse) | PR |
| Q8L4E9 | Os07g0633500 | DEAD-box ATP-dependent RNA helicase 36 | Oryza sativa subsp japonica (Rice) | PR |
| P34580 | T26G10.1 | Putative ATP-dependent RNA helicase T26G10.1 | Caenorhabditis elegans | PR |
| P34668 | ZK686.2 | Putative ATP-dependent RNA helicase ZK686.2 | Caenorhabditis elegans | PR |
| Q9FVV4 | RH55 | DEAD-box ATP-dependent RNA helicase 55 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CAI7 | TIF4A-3 | Eukaryotic initiation factor 4A-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80792 | RH33 | Putative DEAD-box ATP-dependent RNA helicase 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22907 | RH24 | DEAD-box ATP-dependent RNA helicase 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LIH9 | RH51 | DEAD-box ATP-dependent RNA helicase 51 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56X76 | RH39 | DEAD-box ATP-dependent RNA helicase 39 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GY84 | RH10 | DEAD-box ATP-dependent RNA helicase 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FFQ1 | RH31 | DEAD-box ATP-dependent RNA helicase 31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SB89 | RH27 | DEAD-box ATP-dependent RNA helicase 27 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84TG1 | RH57 | DEAD-box ATP-dependent RNA helicase 57 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P41377 | TIF4A-2 | Eukaryotic initiation factor 4A-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P41376 | EIF4A1 | Eukaryotic initiation factor 4A-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8H0U8 | RH42 | DEAD-box ATP-dependent RNA helicase 42 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEPTPEEEG | GITIMSKSRK | NPKTVVNIQS | QKLDSDQNTP | QFEKFTNPNP | SSDTTSATNF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EGLGLAEWAV | ETCKELGMRK | PTPVQTHCVP | KILAGRDVLG | LAQTGSGKTA | AFALPILHRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AEDPYGVFAL | VVTPTRELAF | QLAEQFKALG | SCLNLRCSVI | VGGMDMLTQT | MSLVSRPHIV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ITTPGRIKVL | LENNPDVPPV | FSRTKFLVLD | EADRVLDVGF | QDELRTIFQC | LPKSRQTLLF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SATMTSNLQA | LLEHSSNKAY | FYEAYEGLKT | VDTLTQQFIF | EDKDAKELYL | VHILSQMEDK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GIRSAMIFVS | TCRTCQRLSL | MLDELEVENI | AMHSLNSQSM | RLSALSKFKS | GKVPILLATD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VASRGLDIPT | VDLVINYDIP | RDPRDYVHRV | GRTARAGRGG | LAVSIITETD | VKLIHKIEEE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VGKKMEPYNK | KVITDSLEVT | KVSKAKRVAM | MKMLDNGFED | KVKDRRKLKR | KTLADKGLLK |
| 490 | |||||
| KRGKRQKSTE | N |