Q9QXT1

PR
Gene name
Dapp1 (Bam32)
Protein name
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Names
mDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:26377
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9QXT1

Entry ID Method Resolution Chain Position Source
AF-Q9QXT1-F1 Predicted AlphaFoldDB

11 variants for Q9QXT1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388666540 69 L>I No EVA
rs3388656000 79 S>F No EVA
rs3388661761 121 T>I No EVA
rs3388659462 145 H>R No EVA
rs232161739 155 N>K No EVA
rs3388655931 160 T>I No EVA
rs3388664453 163 S>F No EVA
rs3388666694 205 I>F No EVA
rs3388662145 239 L>I No EVA
rs3388662099 242 K>R No EVA
rs3388660438 278 I>N No EVA

No associated diseases with Q9QXT1

3 regional properties for Q9QXT1

Type Name Position InterPro Accession
domain SH2 domain 33 - 129 IPR000980
domain Pleckstrin homology domain 164 - 261 IPR001849
domain DAPP1, SH2 domain 28 - 119 IPR035843

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Membrane ; Peripheral membrane protein
  • Membrane-associated after cell stimulation leading to its translocation
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
phosphatidylinositol-3,4,5-trisphosphate binding Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
phosphatidylinositol-3,4-bisphosphate binding Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

11 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A4FUB7 GIN1 Gypsy retrotransposon integrase-like protein 1 Bos taurus (Bovine) PR
Q6ZNG9 KRBA2 KRAB-A domain-containing protein 2 Homo sapiens (Human) PR
Q9P2P1 NYNRIN Protein NYNRIN Homo sapiens (Human) PR
Q6R2W3 ZBED9 SCAN domain-containing protein 3 Homo sapiens (Human) PR
Q9UN19 DAPP1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide Homo sapiens (Human) PR
Q94KB1 MLO14 MLO-like protein 14 Arabidopsis thaliana (Mouse-ear cress) PR
O80580 MLO15 MLO-like protein 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SMP1 XTH11 Probable xyloglucan endotransglucosylase/hydrolase protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
O49621 MLO1 MLO-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FK75 At5g45670 GDSL esterase/lipase At5g45670 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FI00 MLO11 MLO-like protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGRAELLGGN MSTQDPSELW GRADGGTDLL QDLGWYHGNL TRHAAEALLL SNGRDGSYLL
70 80 90 100 110 120
RDSNEQTGLY SLSVRAKDSV KHFHVEYTGY SFKFGFNEYS SLKDFVKHFA NQPLIGSETG
130 140 150 160 170 180
TLMVLKHPYP REVEEPCIYE SVRVHTAMQT GRTENDLVPT APSLGTKEGY LTKQGGLVKT
190 200 210 220 230 240
WKTRWFTLQR NELKYFKDQM SPEPIRILDL TECSAVQFDY SQERVNCFCL VFPFRTFYLC
250 260 270
AKTGVEADEW IKILRWKLSK IRKQLDQGED TVRSRSFIFK