AiPD: Autoinhibited Protein Database

Q9P2P1

Gene name	NYNRIN (CGIN1, KIAA1305)
Protein name	Protein NYNRIN
Names	NYN domain and retroviral integrase catalytic domain-containing protein, Protein cousin of GIN1
Species	Homo sapiens (Human)
KEGG Pathway	hsa:57523
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

553-632 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

553-632 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9P2P1

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9P2P1-F1	Predicted				AlphaFoldDB

1531 variants for Q9P2P1

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs1357325762 CA389247565	2	L>F		No	ClinGen TOPMed gnomAD
CA7136513 rs749407541	3	L>P		No	ClinGen ExAC TOPMed gnomAD
CA389247627 rs1477235934	4	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1445582766 CA389247608	4	S>P		No	ClinGen TOPMed gnomAD
CA389247640 rs1326098472	5	G>W		No	ClinGen gnomAD
rs770905855 CA389247667	6	G>D		No	ClinGen ExAC TOPMed gnomAD
CA7136514 rs770905855	6	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1438169552 CA389247769	9	P>S		No	ClinGen gnomAD
rs1363333113 CA389247789	10	A>T		No	ClinGen gnomAD
rs567805123 CA257920310	14	F>C		No	ClinGen Ensembl
CA389248059 rs1216785969	15	M>T		No	ClinGen gnomAD
rs1271364704 CA389248078	16	V>M		No	ClinGen gnomAD
CA389248142 rs1214690970	18	T>A		No	ClinGen gnomAD
TCGA novel	20	S>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs551164226 CA7136517	22	P>A		No	ClinGen 1000Genomes ExAC gnomAD
rs551164226 CA7136518	22	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs765022922 CA7136520	24	V>M		No	ClinGen ExAC gnomAD
rs750094778 CA7136522	25	Q>H		No	ClinGen ExAC gnomAD
CA257920351 rs1045933777	27	Q>R		No	ClinGen Ensembl
rs1594735656 CA389248443	28	R>G		No	ClinGen Ensembl
rs781624995 CA7136526	33	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA257920365 rs781624995	33	R>P		No	ClinGen ExAC TOPMed gnomAD
CA389248637 rs1396281754	35	F>V		No	ClinGen gnomAD
CA7136528 rs756436033	37	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1001630854 CA257920386	39	L>Q		No	ClinGen Ensembl
TCGA novel	40	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136531 rs771121136	42	F>L		No	ClinGen ExAC gnomAD
CA7136532 rs778894536	42	F>Y		No	ClinGen ExAC gnomAD
rs768526460 CA7136534	45	R>L		No	ClinGen ExAC TOPMed gnomAD
CA389248930 rs1332985865	46	P>R		No	ClinGen gnomAD
rs748024470 CA7136536	48	T>N		No	ClinGen ExAC gnomAD
TCGA novel	48	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136537 rs769696897	49	P>R		No	ClinGen ExAC TOPMed gnomAD
CA389249030 rs1302811731	50	Y>F		No	ClinGen TOPMed gnomAD
CA7136539 rs762516672	50	Y>H		No	ClinGen ExAC TOPMed gnomAD
rs1318503497 CA389249076	52	W>C		No	ClinGen TOPMed
CA389249060 rs1213720720	52	W>G		No	ClinGen gnomAD
CA257920482 rs867123197	53	L>V		No	ClinGen TOPMed
CA389249114 rs1345327244	54	Q>*		No	ClinGen TOPMed
rs1566481752 CA389249162	55	L>F		No	ClinGen Ensembl
CA7136541 rs773752081	56	E>Q		No	ClinGen ExAC gnomAD
rs1419698938 CA389249215	57	G>E		No	ClinGen gnomAD
rs759060112 CA7136542	57	G>R		No	ClinGen ExAC TOPMed gnomAD
rs759060112 CA389249208	57	G>W		No	ClinGen ExAC TOPMed gnomAD
rs768048941 CA7136543	58	P>L		No	ClinGen ExAC gnomAD
CA7136544 rs753195603	59	R>Q		No	ClinGen ExAC
CA389249270 rs1310905139	60	E>Q		No	ClinGen gnomAD
rs187697702 CA257920526	62	M>I		No	ClinGen 1000Genomes gnomAD
rs1594735750 CA389249340	62	M>K		No	ClinGen Ensembl
rs764449880 CA7136546	62	M>V		No	ClinGen ExAC gnomAD
TCGA novel	65	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389249498 rs1415878251	66	K>E		No	ClinGen gnomAD
CA389249508 rs1315222102	66	K>R		No	ClinGen TOPMed gnomAD
CA389254777 rs1330868879	70	K>N		No	ClinGen gnomAD
rs1464270461 CA389254762	70	K>R		No	ClinGen gnomAD
CA257929574 rs1009271726	73	C>S		No	ClinGen Ensembl
rs750645928 CA7136569	77	L>R		No	ClinGen ExAC gnomAD
rs758632924 CA7136570	80	E>Q		No	ClinGen ExAC gnomAD
CA7136571 rs780283437	81	V>F		No	ClinGen ExAC TOPMed gnomAD
CA7136572 rs780283437	81	V>L		No	ClinGen ExAC TOPMed gnomAD
CA7136573 rs756142193	82	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA389255196 rs1594739117	83	Y>S		No	ClinGen Ensembl
rs778485525 CA7136577	88	H>L		No	ClinGen ExAC gnomAD
rs1468620371 CA389255390	88	H>Q		No	ClinGen gnomAD
rs745526277 CA7136578	92	L>P		No	ClinGen ExAC gnomAD
CA389255552 rs1365581919	94	A>T		No	ClinGen gnomAD
CA257929623 rs1016527220	95	Q>P		No	ClinGen TOPMed
CA7136582 rs769191962	97	L>F		No	ClinGen ExAC TOPMed gnomAD
CA389255747 rs1477081270	100	D>G		No	ClinGen gnomAD
rs777192126 CA7136583	101	C>G		No	ClinGen ExAC gnomAD
CA389255813 rs1291109902	102	L>F		No	ClinGen TOPMed
rs1395552725 CA389255843	103	C>R		No	ClinGen gnomAD
TCGA novel	105	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1291888653 CA389255936	105	S>N		No	ClinGen gnomAD
CA389255951 rs1594739147	106	T>P		No	ClinGen Ensembl
COSM394429 rs1454804280 CA389255970	107	L>F	lung [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1454804280 CA389255966	107	L>V		No	ClinGen TOPMed
CA389256111 rs1386153416	110	L>V		No	ClinGen TOPMed gnomAD
CA389256292 rs1168225489	113	G>S		No	ClinGen TOPMed
rs571250742 CA257929699	114	P>L		No	ClinGen Ensembl
CA389256331 rs1277310742	114	P>T		No	ClinGen TOPMed gnomAD
CA7136588 rs557266750	115	P>A		No	ClinGen 1000Genomes ExAC gnomAD
rs751733364 CA7136589	117	S>F		No	ClinGen ExAC gnomAD
rs1313240519 CA389256627	119	M>K		No	ClinGen Ensembl
TCGA novel	121	G>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389256756 rs1594739179	122	G>R		No	ClinGen Ensembl
CA7136591 rs777636022	124	T>I		No	ClinGen ExAC gnomAD
rs1487580060 CA389256835	125	E>K		No	ClinGen gnomAD
CA257929732 rs986563058	126	S>C		No	ClinGen TOPMed gnomAD
TCGA novel	126	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136592 rs753798964	128	I>V		No	ClinGen ExAC gnomAD
CA257929759 rs778796771	129	M>K		No	ClinGen Ensembl
rs1566484295 TCGA novel CA389257150	131	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen Ensembl
TCGA novel	131	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136594 rs778802853	133	W>C		No	ClinGen ExAC TOPMed gnomAD
rs757078571 CA7136593	133	W>G		No	ClinGen ExAC gnomAD
CA7136595 rs373561750	137	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1039992473 CA257929771	138	V>L		No	ClinGen TOPMed
rs201881306 COSM3690046 CA7136596	140	R>*	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
COSM1128278 rs1298258264 CA389257532	140	R>Q	Variant assessed as Somatic; impact. prostate [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA7136598 rs746590236	142	R>C		No	ClinGen ExAC gnomAD
CA7136599 rs768200995	142	R>L		No	ClinGen ExAC gnomAD
rs1355781215 CA389257644	143	W>C		No	ClinGen gnomAD
CA389257602 rs867723587	143	W>G		No	ClinGen Ensembl
rs867723587 CA257929789	143	W>R		No	ClinGen Ensembl
COSM552874 CA7136600 rs775948701	144	G>C	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA7136602 rs762384920	144	G>D		No	ClinGen ExAC TOPMed gnomAD
CA7136601 rs762384920	144	G>V		No	ClinGen ExAC TOPMed gnomAD
COSM1477518 CA7136603 rs773733347	145	P>A	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs773733347 CA7136604	145	P>S		No	ClinGen ExAC TOPMed gnomAD
CA7136605 rs766743805	146	A>D		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	146	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389257798 rs1287476104	147	P>H		No	ClinGen gnomAD
rs1168166660 CA389257885	150	T>I		No	ClinGen TOPMed
TCGA novel	150	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	152	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136609 rs376552671	152	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs757243958 CA257929861	152	R>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs757243958 CA7136610	152	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs376552671 CA7136608	152	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA389257963 rs1180476049	153	G>R		No	ClinGen gnomAD
rs552507613 CA7136611	153	G>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389258003 rs1419870273	154	I>V		No	ClinGen gnomAD
rs1161406327 CA389258067	155	W>S		No	ClinGen gnomAD
CA7136612 rs750263825	157	A>D		No	ClinGen ExAC gnomAD
CA7136613 rs370323848	159	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs370323848 CA389258222	159	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA389258263 rs1185749902	160	T>A		No	ClinGen TOPMed
CA389258259 rs1185749902	160	T>S		No	ClinGen TOPMed
CA389258347 rs1471588395	160	T>S		No	ClinGen TOPMed gnomAD
CA7136615 rs572906859 COSM183587	161	R>Q	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
CA7136614 rs373738856	161	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs754522325 CA7136616	162	A>T		No	ClinGen ExAC gnomAD
rs1300836944 CA389258451	163	F>L		No	ClinGen gnomAD
rs1391567850 CA389258496	164	G>E		No	ClinGen gnomAD
rs1479490784 CA389258470	164	G>R		No	ClinGen TOPMed
rs1391567850 CA389258488	164	G>V		No	ClinGen gnomAD
rs770381190 CA7136619	165	A>D		No	ClinGen ExAC gnomAD
CA7136618 rs747561773	165	A>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	167	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749733217 CA7136621	167	V>I		No	ClinGen ExAC TOPMed gnomAD
CA389258593 rs749733217	167	V>L		No	ClinGen ExAC TOPMed gnomAD
rs538522298 CA7136622 COSM3786240	170	R>C	Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1208524247 CA389258720	170	R>H		No	ClinGen TOPMed gnomAD
rs774796152 CA7136623	171	G>R		No	ClinGen ExAC gnomAD
CA389258852 rs1481101281	173	Q>R		No	ClinGen gnomAD
CA7136626 rs558596464	183	P>A		No	ClinGen 1000Genomes ExAC gnomAD
CA7136625 rs558596464	183	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs760640899 CA7136627	184	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1173726975 CA389259227	185	V>I		No	ClinGen gnomAD
CA7136629 rs750350133	186	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs539374112 CA257930020	194	R>Q		No	ClinGen TOPMed gnomAD
rs751312331 CA7136632	194	R>W		No	ClinGen ExAC TOPMed gnomAD
rs905159667 CA257930030	197	A>V		No	ClinGen TOPMed gnomAD
CA7136634 rs202195057	198	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1200897268 CA389259703	198	G>V		No	ClinGen gnomAD
rs747729947 CA7136635	201	D>G		No	ClinGen ExAC gnomAD
rs1252172412 CA389259935	202	I>F		No	ClinGen TOPMed
CA7136637 rs778480620	203	I>L		No	ClinGen ExAC gnomAD
CA389260051 rs771495789	204	E>K		No	ClinGen ExAC gnomAD
CA7136639 rs771495789	204	E>Q		No	ClinGen ExAC gnomAD
CA389260127 rs1566484445	205	W>*		No	ClinGen Ensembl
CA7136640 rs374698906	208	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA7136641 rs746196710	208	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs890504940 CA257930097	210	G>S		No	ClinGen TOPMed gnomAD
rs200319488 CA7136644	213	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA389260596 rs1240145802	213	D>G		No	ClinGen Ensembl
rs764176000 CA7136645	217	D>N		No	ClinGen ExAC TOPMed gnomAD
rs544385173 CA7136646	218	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389260911 rs1276678062	219	E>V		No	ClinGen gnomAD
CA389260989 rs1594739364	220	V>G		No	ClinGen Ensembl
rs751416767 CA7136649	222	I>N		No	ClinGen ExAC gnomAD
rs766253210 CA7136648	222	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1395057616 CA389261068	223	C>F		No	ClinGen TOPMed
rs1449993834 CA389261118	224	P>L		No	ClinGen gnomAD
rs767266661 CA7136651	230	E>K		No	ClinGen ExAC gnomAD
rs752278686 CA7136652	231	A>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	232	P>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753351183 CA7136655	234	M>I		No	ClinGen ExAC TOPMed gnomAD
CA7136654 rs777425106	234	M>L		No	ClinGen ExAC gnomAD
CA389261502 rs777425106	234	M>V		No	ClinGen ExAC gnomAD
CA389261559 rs1346362521	235	V>M		No	ClinGen TOPMed gnomAD
CA7136656 rs757889256	236	S>T		No	ClinGen ExAC TOPMed gnomAD
CA389261599 rs779532173	237	V>L		No	ClinGen ExAC TOPMed gnomAD
CA7136659 rs779532173	237	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1234263299 CA389261620	238	G>A		No	ClinGen gnomAD
rs1286238874 CA389261708	240	S>N		No	ClinGen gnomAD
CA257930178 rs561187132	242	G>R		No	ClinGen 1000Genomes
rs1354469924 CA389261807	242	G>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1284985312 CA389261922	245	V>M		No	ClinGen gnomAD
rs1268008731 CA389261952	246	D>G		No	ClinGen TOPMed
rs772314423 CA7136661	247	M>V		No	ClinGen ExAC gnomAD
CA7136662 COSM283457 rs368004631	248	G>E	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs1481997998 CA389261991	248	G>R		No	ClinGen gnomAD
CA257930193 rs1019381148	249	T>S		No	ClinGen TOPMed
rs747204107 CA7136663	253	R>G		No	ClinGen ExAC gnomAD
CA7136664 rs768828417	253	R>M		No	ClinGen ExAC gnomAD
CA7136666 rs761855742	254	G>C		No	ClinGen ExAC TOPMed
rs181738235 CA7136667	254	G>D		No	ClinGen 1000Genomes ExAC gnomAD
CA257930233 rs761855742	254	G>R		No	ClinGen ExAC TOPMed
rs952646306 CA257930260	256	E>G		No	ClinGen TOPMed
TCGA novel	258	S>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs144241777 CA7136670	259	K>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs144241777 CA7136669	259	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389262491 rs1422071552	260	R>S		No	ClinGen TOPMed gnomAD
rs200156454 CA7136671	260	R>T		No	ClinGen ExAC gnomAD
CA7136674 rs763818709	261	L>F		No	ClinGen ExAC TOPMed gnomAD
CA7136672 rs760433823	261	L>V		No	ClinGen ExAC gnomAD
rs1336532058 CA389262808	265	G>E		No	ClinGen gnomAD
rs1447521358 CA389262987	269	S>Y		No	ClinGen gnomAD
TCGA novel	270	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389263076 rs1280212608	272	T>I		No	ClinGen gnomAD
CA257930316 rs557985460	273	A>P		No	ClinGen TOPMed
CA7136677 rs74036628	275	S>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7136678 COSM86262 rs758876637	277	P>L	ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA257930324 rs758876637	277	P>Q		No	ClinGen ExAC gnomAD
rs768912222 CA7136681	279	E>K		No	ClinGen ExAC gnomAD
CA7136682 rs781357560	280	A>T		No	ClinGen ExAC gnomAD
rs978434923 CA257930359	281	A>V		No	ClinGen TOPMed
rs1594739482 CA389263630	282	N>T		No	ClinGen Ensembl
CA7136684 rs769850739	283	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA7136683 rs748289213	283	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs773284886 CA7136685	284	L>V		No	ClinGen ExAC gnomAD
CA257930393 rs376822294	286	R>Q		No	ClinGen ESP
rs772004028 CA7136687	286	R>W		No	ClinGen ExAC TOPMed gnomAD
rs755328039 CA7136699	287	V>I		No	ClinGen ExAC gnomAD
CA257930500 rs994846671	288	G>C		No	ClinGen TOPMed gnomAD
rs994846671 CA257930498	288	G>S		No	ClinGen TOPMed gnomAD
TCGA novel	289	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1374091338 CA389264288	290	N>K		No	ClinGen TOPMed
CA389264267 rs1476599819	290	N>S		No	ClinGen TOPMed
rs1171796959 CA389264312	291	N>K		No	ClinGen gnomAD
rs867860900 CA257930506	291	N>S		No	ClinGen Ensembl
CA257930511 rs1037695235	292	Q>E		No	ClinGen TOPMed gnomAD
rs1464222690 CA389264423	294	G>D		No	ClinGen gnomAD
rs1464222690 CA389264425	294	G>V		No	ClinGen gnomAD
rs1391462117 CA389264491	295	M>I		No	ClinGen gnomAD
rs1339437007 CA389264429	295	M>L		No	ClinGen gnomAD
CA257930512 rs572019723	295	M>T		No	ClinGen gnomAD
CA7136701 rs748383018	296	D>N		No	ClinGen ExAC gnomAD
rs375922437 CA257930531	297	S>N		No	ClinGen ESP TOPMed gnomAD
rs150643303 CA7136702	297	S>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201047655 CA7136703	298	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389264642 rs1319592259	299	Q>R		No	ClinGen TOPMed gnomAD
CA7136704 rs749337820	300	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs1488555486 CA389264826	303	T>K		No	ClinGen gnomAD
CA389264905 rs1265932641	304	V>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1265932641 CA389264911	304	V>G		No	ClinGen gnomAD
CA7136705 rs771946122	304	V>M		No	ClinGen ExAC gnomAD
CA389264939 rs1441809691	305	Q>*		No	ClinGen gnomAD
rs1294661717 CA389264974	306	A>D		No	ClinGen TOPMed
CA389264959 rs1194880007	306	A>T		No	ClinGen TOPMed gnomAD
rs1476969117 CA389265021	308	S>G		No	ClinGen gnomAD
rs1369262771 CA389265063	309	S>N		No	ClinGen gnomAD
rs369993635 CA7136707	311	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs1459542080 CA389265158	311	D>G		No	ClinGen TOPMed gnomAD
CA389265162 rs1459542080	311	D>V		No	ClinGen TOPMed gnomAD
rs1004150713 CA257930558	313	T>A		No	ClinGen TOPMed
CA7136708 rs768586299	313	T>M		No	ClinGen ExAC TOPMed gnomAD
CA389267863 rs1182661895	315	H>N		No	ClinGen TOPMed gnomAD
CA257930599 rs959886093	316	T>I		No	ClinGen TOPMed
CA257930598 rs959886093	316	T>R		No	ClinGen TOPMed
rs1397898732 CA389267945	317	Q>K		No	ClinGen gnomAD
rs772650230 CA7136712	318	A>D		No	ClinGen ExAC TOPMed gnomAD
rs772650230 CA389268027	318	A>G		No	ClinGen ExAC TOPMed gnomAD
CA7136711 rs139819869	318	A>S		No	ClinGen 1000Genomes ExAC gnomAD
rs772650230 CA7136713	318	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1263114959 CA389268145	321	K>T		No	ClinGen gnomAD
rs1359398019 CA389268175	322	Q>E		No	ClinGen TOPMed gnomAD
rs1359398019 CA389268172	322	Q>K		No	ClinGen TOPMed gnomAD
rs113119792 CA7136715 CA7136716	323	R>S		No	ClinGen TOPMed gnomAD
CA389268293 rs1594739686	325	V>G		No	ClinGen Ensembl
rs752044926 CA7136718	325	V>I		No	ClinGen ExAC TOPMed gnomAD
CA7136719 rs755419891	327	K>E		No	ClinGen ExAC TOPMed gnomAD
rs1170612364 CA389268392	327	K>N		No	ClinGen TOPMed gnomAD
rs767871241 CA7136720	327	K>T		No	ClinGen ExAC gnomAD
CA7136721 rs753017990	329	E>G		No	ClinGen ExAC gnomAD
CA389268532 rs1594739693	331	K>N		No	ClinGen Ensembl
CA257930681 rs74860786	334	F>S		No	ClinGen Ensembl
CA389268655 rs1372025774	336	P>T		No	ClinGen TOPMed
rs975595029 CA257930695	337	P>S		No	ClinGen TOPMed gnomAD
CA389268722 rs1425728786	338	V>I		No	ClinGen gnomAD
rs756310955 CA7136722	339	S>P		No	ClinGen ExAC gnomAD
TCGA novel	340	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136723 rs778026341	342	G>D		No	ClinGen ExAC gnomAD
rs1159240810 CA389268920	343	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA389268904 rs1159240810	343	V>M		No	ClinGen TOPMed gnomAD
CA389268980 rs1397254471 COSM1607570	344	C>Y	liver [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1362375049 CA389269027	345	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA7136724 rs749396579	347	W>G		No	ClinGen ExAC TOPMed gnomAD
CA7136725 rs757347389	351	T>S		No	ClinGen ExAC gnomAD
rs779079283 CA7136726	352	P>L		No	ClinGen ExAC TOPMed gnomAD
CA257930714 rs925632200	352	P>S		No	ClinGen Ensembl
CA7136728 rs768678577	353	G>R		No	ClinGen ExAC TOPMed gnomAD
CA389269511 rs1566484761	354	P>R		No	ClinGen Ensembl
CA7136730 rs373163147	361	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7136732 rs772910282	363	A>T		No	ClinGen ExAC TOPMed gnomAD
CA389269937 rs1274926005	363	A>V		No	ClinGen TOPMed
rs762424673 CA7136733	365	A>S		No	ClinGen ExAC gnomAD
rs765924476 CA7136734	365	A>V		No	ClinGen ExAC gnomAD
rs1297732127 CA389270139	368	F>L		No	ClinGen TOPMed gnomAD
rs944886130 CA257930751	370	R>K		No	ClinGen Ensembl
CA257930767 rs370739201	372	N>K		No	ClinGen ESP TOPMed
CA7136735 rs773783660	372	N>S		No	ClinGen ExAC gnomAD
CA7136736 rs760066988	375	H>Q		No	ClinGen ExAC gnomAD
CA389270342 rs1566484793	375	H>R		No	ClinGen Ensembl
rs1039650678 CA257930798	377	L>P		No	ClinGen Ensembl
rs1437695896 CA389270438	378	H>Y		No	ClinGen gnomAD
CA389270527 rs1158147852	380	A>S		No	ClinGen gnomAD
CA389270540 rs1359460945	380	A>V		No	ClinGen gnomAD
CA7136739 rs200284224	382	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1439100793 CA389270635	382	L>P		No	ClinGen TOPMed
CA7136741 rs375919152	386	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1375365505 CA389270799	387	C>F		No	ClinGen gnomAD
rs779169130 CA7136743	387	C>R		No	ClinGen ExAC gnomAD
rs1375365505 CA389270805	387	C>S		No	ClinGen gnomAD
CA257930856 rs940699754	389	N>D		No	ClinGen Ensembl
CA389270907 rs1343504670	389	N>S		No	ClinGen TOPMed
CA389270932 rs1223651699	390	F>Y		No	ClinGen gnomAD
rs750485412 CA7136744	391	P>R		No	ClinGen ExAC gnomAD
CA389270944 rs1302427181	391	P>S		No	ClinGen gnomAD
CA389270945 rs1302427181	391	P>T		No	ClinGen gnomAD
rs1208455558 CA389270999	393	W>R		No	ClinGen gnomAD
rs1262797212 CA389271015	394	Q>E		No	ClinGen gnomAD
CA389271069 rs1161291091	395	R>S		No	ClinGen TOPMed
CA7136746 rs781246698	396	P>L		No	ClinGen ExAC gnomAD
CA7136747 rs781246698	396	P>R		No	ClinGen ExAC gnomAD
rs929300856 CA257930862	396	P>S		No	ClinGen TOPMed
rs1200627965	400	I>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs1468540953 CA389271354	402	L>W		No	ClinGen gnomAD
rs1173663517 CA389271493	406	G>R		No	ClinGen gnomAD
TCGA novel	408	N>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389271662 rs1428188971	409	P>L		No	ClinGen gnomAD
rs773871684 CA7136752	411	P>S		No	ClinGen ExAC gnomAD
CA7136753 rs759022803	413	N>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	416	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772635571 CA7136754	418	Q>K		No	ClinGen ExAC gnomAD
rs775964488 CA7136755	419	K>R		No	ClinGen ExAC gnomAD
CA7136756 rs200184423	420	E>K		No	ClinGen ExAC TOPMed gnomAD
CA7136757 rs201508215	420	E>V		No	ClinGen ExAC TOPMed gnomAD
rs1477951921 CA389272095	422	A>S		No	ClinGen TOPMed gnomAD
CA7136758 rs754115535	423	P>R		No	ClinGen ExAC gnomAD
rs748401666 CA257930916	425	P>L		No	ClinGen TOPMed gnomAD
rs1231684808 CA389272215	425	P>S		No	ClinGen TOPMed
rs762121476 CA7136759	426	S>N		No	ClinGen ExAC gnomAD
rs1032749252 CA257930930	427	A>T		No	ClinGen gnomAD
rs750575048 CA7136761	429	S>G		No	ClinGen ExAC gnomAD
CA7136762 rs758545618	429	S>N		No	ClinGen ExAC gnomAD
rs1172444035 CA389272455	430	P>R		No	ClinGen gnomAD
rs1477949724 CA389272447	430	P>T		No	ClinGen gnomAD
CA389272537 rs1408904562	432	G>D		No	ClinGen gnomAD
CA7136763 rs781334023	432	G>S		No	ClinGen ExAC gnomAD
rs752690083 CA7136764	434	P>L		No	ClinGen ExAC gnomAD
CA7136767 rs777654963 CA389272642	436	G>R		No	ClinGen ExAC TOPMed gnomAD
rs777654963 CA7136766	436	G>W		No	ClinGen ExAC TOPMed gnomAD
rs191695865 CA7136768	437	G>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA389272705 rs1341459104	437	G>R		No	ClinGen gnomAD
rs1427934210	438	L>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136771 rs771586058	439	G>E		No	ClinGen ExAC TOPMed gnomAD
CA257930967 rs1009187314	442	A>S		No	ClinGen TOPMed
rs922107081 CA257930979	445	Q>K		No	ClinGen TOPMed
CA389273355 rs1320570953	453	S>A		No	ClinGen gnomAD
rs771537997 CA257930999	455	K>E		No	ClinGen Ensembl
CA257931005 rs930821239	455	K>R		No	ClinGen TOPMed
rs368386544 CA7136775	456	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA7136777 rs762055012	457	T>A		No	ClinGen ExAC TOPMed gnomAD
rs12437434 CA7136778 VAR_037857	457	T>M		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA7136776 rs762055012	457	T>P		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	458	S>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1423309439 CA389273592	458	S>N		No	ClinGen TOPMed gnomAD
CA389273578 rs1415252556	458	S>R		No	ClinGen TOPMed gnomAD
rs1163575561 CA389273768	462	V>A		No	ClinGen gnomAD
CA389273841 rs1421951732	463	P>R		No	ClinGen gnomAD
rs766567921 CA7136780	463	P>S		No	ClinGen ExAC gnomAD
CA7136781 rs751550168	464	G>R		No	ClinGen ExAC gnomAD
rs940669989 CA257931045	465	S>N		No	ClinGen Ensembl
CA7136784 rs753706025	467	D>G		No	ClinGen ExAC TOPMed gnomAD
rs149771079 CA7136783	467	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7136782 rs149771079	467	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7136785 rs757034250	468	V>A		No	ClinGen ExAC TOPMed gnomAD
CA389274171 rs1245330388	469	K>R		No	ClinGen gnomAD
rs745524157 CA7136787 COSM955061	470	D>G	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA7136789 rs760202880	474	S>L		No	ClinGen ExAC TOPMed gnomAD
CA7136788 rs758007159	474	S>P		No	ClinGen ExAC gnomAD
CA389274317 rs1297844334	475	D>A		No	ClinGen TOPMed
CA389274408 COSM283458 rs1352588616	478	Q>H	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs777003032 CA7136792	478	Q>K		No	ClinGen ExAC gnomAD
CA7136793 rs375351963	478	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA257931167 rs867297643	480	G>E		No	ClinGen Ensembl
CA389274538 rs1594739993	484	T>A		No	ClinGen Ensembl
rs773641062 CA7136795	485	S>F		No	ClinGen ExAC gnomAD
rs1381533525 CA389274633	486	T>A		No	ClinGen gnomAD
rs1157227112 CA389274666	487	P>H		No	ClinGen gnomAD
CA389274668 rs1157227112	487	P>L		No	ClinGen gnomAD
TCGA novel	488	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763296422 CA7136796	489	L>R		No	ClinGen ExAC gnomAD
CA7136797 rs766462162	490	Q>*		No	ClinGen ExAC gnomAD
CA389274737 rs766462162	490	Q>E		No	ClinGen ExAC gnomAD
TCGA novel	490	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA257931189 rs763697962	491	A>P		No	ClinGen gnomAD
rs1417083964 CA389274841	494	E>K		No	ClinGen TOPMed
CA7136799 rs367907615	495	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA7136800 rs367907615	495	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA7136798 rs774539372	495	P>S		No	ClinGen ExAC gnomAD
TCGA novel	496	G>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA257931238 rs1032716633	498	Q>E		No	ClinGen TOPMed gnomAD
CA7136803 rs765047927	499	G>R		No	ClinGen ExAC TOPMed gnomAD
rs944909212 CA257931248	500	S>R		No	ClinGen TOPMed gnomAD
CA389275038 rs1202493172	501	M>I		No	ClinGen TOPMed gnomAD
CA389275013 rs1459687417	501	M>V		No	ClinGen gnomAD
rs528511265 CA7136804	502	Q>H		No	ClinGen 1000Genomes ExAC gnomAD
rs1459499346 CA389275129	504	D>N		No	ClinGen TOPMed gnomAD
CA389275125 rs1459499346	504	D>Y		No	ClinGen TOPMed gnomAD
rs779545570 CA389275200	507	G>E		No	ClinGen ExAC TOPMed gnomAD
rs375728700 CA7136805	507	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs779545570 CA7136806	507	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1306523805 CA389275210	508	L>V		No	ClinGen TOPMed
CA7136807 rs746599929	509	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs369906228 CA7136808	511	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA7136810 rs748667976	513	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs770381425 CA7136811	513	A>V		No	ClinGen ExAC TOPMed gnomAD
CA7136812 rs773731159	514	P>A		No	ClinGen ExAC gnomAD
CA389275437 rs1594740072	515	V>L		No	ClinGen Ensembl
rs199653140 CA7136813	518	T>A		No	ClinGen ExAC TOPMed gnomAD
rs375391398 CA7136814	518	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs199653140 CA257931316	518	T>S		No	ClinGen ExAC TOPMed gnomAD
rs774430926 CA7136815	520	Q>P		No	ClinGen ExAC gnomAD
CA389275578 rs1159429851	521	G>E		No	ClinGen gnomAD
CA7136818 rs373058068 COSM955062	524	V>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA7136819 rs761763445	525	A>T		No	ClinGen ExAC gnomAD
CA389275707 rs1193569458	526	Q>H		No	ClinGen gnomAD
COSM3401268 CA389275726 rs1452634221	527	G>E	Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA389275711 rs1250512409	527	G>R		No	ClinGen gnomAD
rs1452634221 CA389275729	527	G>V		No	ClinGen TOPMed gnomAD
CA389275838 rs1201469815	532	Q>*		No	ClinGen gnomAD
CA7136820 rs765139986	532	Q>H		No	ClinGen ExAC gnomAD
CA389275844 rs1267162055	532	Q>P		No	ClinGen gnomAD
rs1171716968 CA389275918	535	P>L		No	ClinGen TOPMed gnomAD
rs750261872 CA7136821	536	G>A		No	ClinGen ExAC TOPMed gnomAD
rs1167391649 CA389275996	538	Q>P		No	ClinGen gnomAD
rs762736202 CA7136822	539	T>I		No	ClinGen ExAC gnomAD
rs766117294 CA7136823	540	V>A		No	ClinGen ExAC gnomAD
TCGA novel	540	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389276079 rs1310293050	541	P>L		No	ClinGen TOPMed
CA389276063 rs1304758970	541	P>S		No	ClinGen gnomAD
rs1404079617 CA389276116	543	T>S		No	ClinGen gnomAD
CA7136826 rs754588570	547	P>L		No	ClinGen ExAC gnomAD
rs1566485096 CA389276296	548	M>V		No	ClinGen Ensembl
rs780596395 CA7136827	549	A>T		No	ClinGen ExAC gnomAD
rs756732851 CA7136829	555	A>D		No	ClinGen ExAC gnomAD
rs992141487 CA257931369	555	A>P		No	ClinGen Ensembl
rs200584757 CA7136831	556	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs145724098 CA7136833	557	N>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7136832 rs771185887	557	N>Y		No	ClinGen ExAC gnomAD
CA389276753 rs1451015837	558	P>R		No	ClinGen TOPMed
CA257931384 rs267603970	558	P>S		No	ClinGen TOPMed
rs267603970 CA389276747	558	P>T		No	ClinGen TOPMed
rs927248858 CA257931388	560	R>G		No	ClinGen Ensembl
CA389276817 rs1192562964	560	R>I		No	ClinGen gnomAD
rs1369086851 CA389276825	561	T>A		No	ClinGen gnomAD
rs377093455 CA7136836 CA389276912	562	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs370185858 CA7136838	564	P>L		No	ClinGen ESP ExAC gnomAD
TCGA novel	564	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	565	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773124937 CA7136839	566	A>V		No	ClinGen ExAC gnomAD
CA257931404 rs866326115	567	A>T		No	ClinGen TOPMed gnomAD
rs762894342 CA7136840	568	P>A		No	ClinGen ExAC TOPMed gnomAD
rs762894342 CA389277111	568	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1594740180 CA389277154	569	K>Q		No	ClinGen Ensembl
rs1363644344 CA389277177	569	K>R		No	ClinGen TOPMed gnomAD
CA389277186 rs1380129203	570	L>M		No	ClinGen TOPMed gnomAD
CA7136842 rs766088225	571	P>S		No	ClinGen ExAC TOPMed gnomAD
rs766088225 CA7136841	571	P>T		No	ClinGen ExAC TOPMed gnomAD
CA7136843 COSM955063 rs759130124	574	R>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA7136844 rs767253660	574	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs752294572 CA7136845	575	M>V		No	ClinGen ExAC gnomAD
CA389277451 rs1233901525	576	M>I		No	ClinGen TOPMed
rs1217821801 CA389277413	576	M>L		No	ClinGen gnomAD
CA389277415 rs1217821801	576	M>V		No	ClinGen gnomAD
rs755678771 CA7136846	578	A>P		No	ClinGen ExAC gnomAD
rs755678771 CA7136847	578	A>T		No	ClinGen ExAC gnomAD
CA7136848 rs754402081	578	A>V		No	ClinGen ExAC gnomAD
CA257931446 rs1054220452	579	V>G		No	ClinGen Ensembl
CA7136850 rs375647768	580	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA389277636 rs1443860955	581	T>A		No	ClinGen gnomAD
CA7136853 rs377709968	582	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA389277757 rs1451330282	583	P>R		No	ClinGen gnomAD
CA7136854 rs371037597	586	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs368022553 CA7136856	587	E>K	Variant assessed as Somatic; 4.694e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA7136857 rs371945048	588	V>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs770851041 CA7136858	589	P>L		No	ClinGen ExAC TOPMed gnomAD
CA389278044 rs1382697072	589	P>S		No	ClinGen gnomAD
CA7136859 rs532810477	593	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1238777240 CA389278227	594	K>N		No	ClinGen gnomAD
rs201954983 CA7136861	597	A>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA389278308 rs1201859441	597	A>P		No	ClinGen gnomAD
CA389278332 rs1182093807	598	Q>*		No	ClinGen gnomAD
rs1460834735 CA389278397	599	L>P		No	ClinGen gnomAD
rs867127147 CA257931478	602	T>A		No	ClinGen gnomAD
CA389278517 rs1417150286	603	A>T		No	ClinGen gnomAD
CA7136862 rs767343609	606	T>A		No	ClinGen ExAC gnomAD
TCGA novel	606	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767343609 CA257931482	606	T>P		No	ClinGen ExAC gnomAD
TCGA novel	606	T>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1217581484 CA389278710	607	V>A		No	ClinGen Ensembl
rs760345842 CA389278815	611	P>S		No	ClinGen ExAC gnomAD
CA7136864 rs760345842	611	P>T		No	ClinGen ExAC gnomAD
CA389279080 rs1372964984	618	E>*		No	ClinGen TOPMed
CA389279123 rs1391194816	619	P>L		No	ClinGen gnomAD
CA389279113 rs1371799502	619	P>S		No	ClinGen gnomAD
CA389279130 rs1191717861	620	T>A		No	ClinGen TOPMed
CA389279194 rs1250331726	622	P>Q		No	ClinGen gnomAD
CA389279205 rs1302337890	623	K>N		No	ClinGen gnomAD
rs1325965983 CA389279216	624	T>I		No	ClinGen gnomAD
rs1221861529 CA389279229	625	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA389279235 rs1262726450	626	Q>*		No	ClinGen gnomAD
rs757756582 CA7136867	626	Q>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	626	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389279278 rs1234589082	627	A>G		No	ClinGen gnomAD
CA389279297 rs1479582727	628	Q>*		No	ClinGen gnomAD
rs1264066649 CA389279308	628	Q>L		No	ClinGen TOPMed
CA257931505 rs867633221	630	M>I		No	ClinGen gnomAD
CA389279397 rs1269279065	631	P>L		No	ClinGen gnomAD
CA257931509 rs1015112049	632	V>L		No	ClinGen gnomAD
CA257931511 rs962096321	637	P>L		No	ClinGen Ensembl
rs765746103 CA7136869	637	P>S		No	ClinGen ExAC TOPMed gnomAD
CA389279545 rs1465745149	638	A>T		No	ClinGen gnomAD
CA7136871 rs376129072	639	G>A		No	ClinGen ExAC TOPMed gnomAD
CA389279567 rs1353275813	639	G>C		No	ClinGen gnomAD
rs376129072 CA389279576	639	G>D		No	ClinGen ExAC TOPMed gnomAD
CA7136872 RCV000960063 rs145306004	641	K>Q		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA389279648 rs1347838752	642	T>A		No	ClinGen gnomAD
CA7136873 rs747240099	643	P>S		No	ClinGen ExAC TOPMed gnomAD
rs755150065 CA7136874	644	K>R		No	ClinGen ExAC gnomAD
rs1566485289 CA389279869	647	A>G		No	ClinGen Ensembl
CA7136875 rs781268310	647	A>T		No	ClinGen ExAC gnomAD
CA7136877 rs770811678	648	G>R		No	ClinGen ExAC gnomAD
rs1203669104 CA389279957	650	A>T		No	ClinGen gnomAD
rs1292376531 CA389279982	650	A>V		No	ClinGen gnomAD
CA257931526 rs936291554	651	A>G		No	ClinGen TOPMed gnomAD
CA257931536 rs796887667	652	T>A		No	ClinGen Ensembl
CA7136879 rs147608016	653	V>A		No	ClinGen 1000Genomes TOPMed
CA389280142 rs1267752553	654	S>P		No	ClinGen TOPMed gnomAD
CA7136882 rs774339840 CA7136883	655	K>N		No	ClinGen ExAC TOPMed gnomAD
CA389280259 rs1187797357	656	A>P		No	ClinGen TOPMed gnomAD
rs1187797357 CA389280254	656	A>T		No	ClinGen TOPMed gnomAD
CA389280284 rs1416712002	656	A>V		No	ClinGen gnomAD
CA389280305 rs1408841206	657	P>L		No	ClinGen gnomAD
rs1367997178 CA389280312	658	A>T		No	ClinGen gnomAD
rs1474280593 CA389280345	659	A>P		No	ClinGen TOPMed
VAR_037858 rs8008203 CA257931557	659	A>V		No	ClinGen UniProt 1000Genomes ESP TOPMed dbSNP gnomAD
CA7136885 rs371964335	660	S>A		No	ClinGen ESP ExAC TOPMed
CA7136886 rs371964335	660	S>P		No	ClinGen ESP ExAC TOPMed
TCGA novel	662	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200060308 CA7136888	663	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs543003504 CA257931582	664	A>T		No	ClinGen gnomAD
CA389280556 rs1433103582	664	A>V		No	ClinGen gnomAD
rs1268510020 CA389280619	666	P>S		No	ClinGen TOPMed gnomAD
CA389280655 rs1196673219	667	K>E		No	ClinGen TOPMed
CA257931585 rs796386133	668	V>A		No	ClinGen TOPMed gnomAD
rs1361415676 CA389280750	669	P>S		No	ClinGen TOPMed gnomAD
rs1315720504 CA389280809	670	V>A		No	ClinGen gnomAD
CA7136890 rs761385721	672	P>T		No	ClinGen ExAC
TCGA novel	674	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1594740413 CA389281029	675	S>Y		No	ClinGen Ensembl
rs1217559901 CA389281036	676	R>G		No	ClinGen gnomAD
rs750958289 CA7136892	677	A>T		No	ClinGen ExAC gnomAD
rs1474833203 CA389281136	678	P>A		No	ClinGen gnomAD
rs758838841 CA7136893	678	P>L		No	ClinGen ExAC TOPMed gnomAD
rs758838841 CA7136894	678	P>R		No	ClinGen ExAC TOPMed gnomAD
rs868791706 CA257931612	679	K>Q		No	ClinGen TOPMed gnomAD
rs368211399 CA257931613	680	T>I		No	ClinGen gnomAD
rs755240078 CA7136896	681	P>L		No	ClinGen ExAC gnomAD
CA7136895 rs751868586	681	P>S		No	ClinGen ExAC gnomAD
CA7136897 rs781442512	682	A>V		No	ClinGen ExAC gnomAD
CA389281345 rs1316546284	684	Q>H		No	ClinGen gnomAD
rs554700851 COSM955066 CA7136900	687	P>L	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA7136899 rs756203827	687	P>S		No	ClinGen ExAC TOPMed gnomAD
rs756203827 CA389281450	687	P>T		No	ClinGen ExAC TOPMed gnomAD
rs764918846 CA7136901	688	T>M		No	ClinGen ExAC gnomAD
rs994794590 CA257931659	689	D>N		No	ClinGen TOPMed gnomAD
rs994794590 CA389281526	689	D>Y		No	ClinGen TOPMed gnomAD
rs1401601689 CA389281652	690	A>S		No	ClinGen TOPMed
rs1225255237 CA389281656	690	A>V		No	ClinGen gnomAD
CA389281670 rs1446002548	691	G>R		No	ClinGen gnomAD
rs1244401113 CA389281736	692	P>L		No	ClinGen gnomAD
rs1364845353 CA389281846	695	D>G		No	ClinGen gnomAD
CA7136905 rs768490988	695	D>N		No	ClinGen ExAC gnomAD
CA389281980 rs1471396298	697	A>V		No	ClinGen gnomAD
rs1344589737 CA389282082	700	L>R		No	ClinGen Ensembl
rs761316892 CA7136907	700	L>V		No	ClinGen ExAC TOPMed gnomAD
CA389282092 rs1470404789	701	S>R		No	ClinGen gnomAD
CA7136908 rs769355894	703	V>D		No	ClinGen ExAC
rs1451969475 CA389282503	709	A>V		No	ClinGen gnomAD
CA7136910 rs772560646	710	S>N		No	ClinGen ExAC gnomAD
rs996204726 CA257931673	711	V>F		No	ClinGen gnomAD
rs1444124416 CA389282591	712	S>P		No	ClinGen gnomAD
CA389282568 rs1444124416	712	S>T		No	ClinGen gnomAD
CA389282705 rs1349543193	713	L>F		No	ClinGen gnomAD
TCGA novel	715	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs766844716 CA7136912	716	G>S		No	ClinGen ExAC gnomAD
rs1320850066 CA389282798	717	Q>E		No	ClinGen TOPMed gnomAD
CA389282874 rs1251889751	718	G>E		No	ClinGen gnomAD
CA7136914 rs759887246	720	A>T		No	ClinGen ExAC gnomAD
RCV000893795 rs200984430 CA7136915	721	G>R		No	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
rs1006494539 CA389282976	722	R>S		No	ClinGen gnomAD
TCGA novel rs1594740513 CA389283043	724	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA Ensembl
rs1201916164 CA389283074	725	P>L		No	ClinGen gnomAD
CA7136916 rs752976271	726	Q>P		No	ClinGen ExAC gnomAD
rs1397129123 CA389283165	728	S>T		No	ClinGen gnomAD
TCGA novel	730	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1411553125 CA389283263	730	T>S		No	ClinGen TOPMed gnomAD
CA389283358 rs1238677972	732	A>D		No	ClinGen TOPMed
rs376464969 CA7136918	732	A>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA7136919 rs376464969	732	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7136921 rs750271245	734	S>R		No	ClinGen ExAC TOPMed gnomAD
rs182330062 CA7136923	735	S>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs182330062 CA7136922	735	S>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1228398813 CA389283537	736	K>N		No	ClinGen TOPMed
CA257931710 rs780786827	737	H>Q		No	ClinGen ExAC
CA389283542 rs1349432394	737	H>Y		No	ClinGen TOPMed
COSM1369400 CA389283653 rs1448322458	739	F>L	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA389283747 rs1343195473	742	E>V		No	ClinGen TOPMed gnomAD
rs747870883 CA7136925	744	L>V		No	ClinGen ExAC gnomAD
rs1351685122 CA389283959	750	G>R		No	ClinGen TOPMed
TCGA novel	751	A>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389284028 rs1342119984	752	P>S		No	ClinGen gnomAD
CA389284107 rs1400214089	754	Q>H		No	ClinGen TOPMed
CA7136927 rs772825031	754	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs1160718241 CA389284126	755	P>L		No	ClinGen TOPMed
rs559761812 CA7136929	755	P>S		No	ClinGen ExAC TOPMed gnomAD
CA7136928 rs559761812	755	P>T		No	ClinGen ExAC TOPMed gnomAD
rs774825048 CA7136930	756	P>L		No	ClinGen ExAC TOPMed gnomAD
rs267603971 CA7136931	757	R>C		No	ClinGen ExAC TOPMed gnomAD
COSM955067 rs201382639 CA7136932	757	R>H	endometrium [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1480192933 CA389284207	758	H>Q		No	ClinGen gnomAD
rs752963794 CA389284278	761	A>G		No	ClinGen ExAC gnomAD
CA7136933 rs752963794 COSM955068	761	A>V	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs371144068 CA7136936	762	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1166125350 CA389284352	763	S>T		No	ClinGen gnomAD
CA389284672 rs1304664474	771	Y>*		No	ClinGen gnomAD
CA7136938 rs765352066	771	Y>C		No	ClinGen ExAC gnomAD
rs1363368161 CA389284696	772	H>R		No	ClinGen gnomAD
CA389284723 rs1295825406	773	E>K		No	ClinGen gnomAD
TCGA novel	774	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1594740607 CA389284770	774	A>V		No	ClinGen Ensembl
rs755826892 CA389284901	780	E>*		No	ClinGen ExAC TOPMed gnomAD
rs755826892 CA7136943	780	E>K		No	ClinGen ExAC TOPMed gnomAD
CA7136944 rs372080002	780	E>V		No	ClinGen ExAC TOPMed gnomAD
rs766395717 CA7136946	785	G>E		No	ClinGen ExAC TOPMed gnomAD
CA389285122 rs1165269034	786	E>D		No	ClinGen gnomAD
CA7136948 rs370769954	786	E>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7136947 rs377683866	786	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs751504287 CA7136950	787	P>A		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	787	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751504287 CA7136949	787	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1189181625 CA389285217	790	Q>E		No	ClinGen TOPMed
rs1420614356 CA389285240	790	Q>H		No	ClinGen TOPMed
rs547141864 CA7136951	790	Q>P		No	ClinGen 1000Genomes ExAC gnomAD
rs547141864 CA257931809	790	Q>R		No	ClinGen 1000Genomes ExAC gnomAD
rs777009648 CA7136953	791	G>A		No	ClinGen ExAC gnomAD
rs781272668 CA7136952	791	G>R		No	ClinGen ExAC gnomAD
CA389285288 rs777009648	791	G>V		No	ClinGen ExAC gnomAD
rs765443117 CA7136955	793	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs762063546 CA7136954	793	R>W		No	ClinGen ExAC TOPMed gnomAD
rs750485430 CA7136956	794	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1594740647 CA389285379	795	V>G		No	ClinGen Ensembl
rs754988176 CA7136957	795	V>M		No	ClinGen ExAC gnomAD
CA257931833 rs62000678	797	I>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs752600470 CA7136959	797	I>T		No	ClinGen ExAC
CA389285504 rs1262773359	799	G>D		No	ClinGen gnomAD
CA7136961 rs777484499	799	G>S		No	ClinGen ExAC gnomAD
TCGA novel	799	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7136962 rs748942924	801	S>G		No	ClinGen ExAC gnomAD
rs1474782349 CA389285611	801	S>N		No	ClinGen TOPMed
CA257931837 rs756372580	802	V>A		No	ClinGen TOPMed
CA389285643 rs756372580	802	V>E		No	ClinGen TOPMed
rs1204666371 CA389285687	804	M>V		No	ClinGen gnomAD
rs756862512 CA7136963	805	V>M		No	ClinGen ExAC gnomAD
rs1269166343 CA389287728	809	Q>R		No	ClinGen gnomAD
rs764954975 CA7137000	811	F>Y		No	ClinGen ExAC gnomAD
rs780897384	812	F>missing	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA389287873 rs1353257595	814	C>F		No	ClinGen gnomAD
CA257932809 rs971821030	815	R>*		No	ClinGen gnomAD
CA257932812 rs368644928	815	R>Q		No	ClinGen ESP TOPMed gnomAD
CA389287970 rs1367723124	818	A>V		No	ClinGen gnomAD
CA7137003 rs370778319	819	M>I		No	ClinGen ExAC TOPMed gnomAD
rs772745095 CA7137002	819	M>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA389288032 rs1408582861	821	V>L		No	ClinGen TOPMed
CA7137007 rs748584472	822	Q>H		No	ClinGen ExAC gnomAD
CA7137006 rs781762444	822	Q>P		No	ClinGen ExAC gnomAD
rs1339900581 CA389288099	823	F>S		No	ClinGen gnomAD
rs1292177693 CA389288213 COSM1218142	827	R>Q	large_intestine [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs770299659 CA7137008	827	R>W		No	ClinGen ExAC gnomAD
TCGA novel	828	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1490773659 CA389288245	829	H>Q		No	ClinGen gnomAD
CA7137009 rs371937730	830	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs540767530 CA7137010	830	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA389288255 rs1187704898	831	E>K		No	ClinGen gnomAD
CA7137012 rs780845306	832	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	833	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs747717073 CA257932848	838	T>S		No	ClinGen Ensembl
rs776562470 CA7137015	842	K>R		No	ClinGen ExAC gnomAD
rs376203691 CA7137016	845	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs1345997753 CA389288543	846	R>K		No	ClinGen TOPMed gnomAD
rs1345997753 CA389288536	846	R>M		No	ClinGen TOPMed gnomAD
CA7137036 rs192585061	849	E>D		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	850	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389288772 rs1327945008	851	H>Y		No	ClinGen TOPMed gnomAD
rs762799957 COSM955070 CA7137038	854	T>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA389288969 rs1441123158	857	H>D		No	ClinGen gnomAD
CA389288964 rs1441123158	857	H>Y		No	ClinGen gnomAD
CA7137039 rs547499850	858	S>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	860	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759200905 CA7137041	861	M>L		No	ClinGen ExAC gnomAD
CA389289223 rs1470352390	864	I>M		No	ClinGen gnomAD
rs112923621 CA257933028	868	Q>K		No	ClinGen Ensembl
rs1404311583 CA389289410	869	L>P		No	ClinGen gnomAD
CA7137043 rs752207041	870	E>Q		No	ClinGen ExAC gnomAD
rs1411421778 CA389289537	873	K>E		No	ClinGen gnomAD
rs764632691 CA7137045	877	T>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	878	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779080140 CA7137048	881	R>W		No	ClinGen ExAC gnomAD
rs751644731 CA7137069	884	V>L		No	ClinGen ExAC gnomAD
TCGA novel	885	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1345734969 CA389291930	887	A>G		No	ClinGen TOPMed
CA7137071 rs755102842	887	A>S		No	ClinGen ExAC TOPMed gnomAD
rs1388058127 CA389291939	888	E>*		No	ClinGen gnomAD
rs1318130078 CA389292035	892	G>S		No	ClinGen TOPMed
rs367836202 CA257936361	893	I>T		No	ClinGen ESP TOPMed gnomAD
rs749282422 CA7137073	900	I>F		No	ClinGen ExAC gnomAD
TCGA novel	901	H>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs979292744 CA257936374	901	H>L		No	ClinGen Ensembl
rs946550334 CA257936369	901	H>Y		No	ClinGen Ensembl
rs1247420191 CA389292309	904	M>R		No	ClinGen gnomAD
CA7137074 rs770727942	906	S>C		No	ClinGen ExAC TOPMed gnomAD
CA389292355 rs1355821906	906	S>N		No	ClinGen gnomAD
TCGA novel	908	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770637725 CA7137076	910	L>P		No	ClinGen ExAC TOPMed gnomAD
rs1463581756 CA389292477	913	K>Q		No	ClinGen gnomAD
CA7137077 rs771918596	913	K>R		No	ClinGen ExAC gnomAD
rs935110217 CA257936391	914	D>G		No	ClinGen Ensembl
rs775268808 CA7137078	915	R>C		No	ClinGen ExAC TOPMed gnomAD
rs775268808 CA389292518	915	R>G		No	ClinGen ExAC TOPMed gnomAD
rs200022118 CA7137079	915	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs368021960 CA7137097	918	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs372202987 CA7137098	922	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137102 rs763387579	931	D>E		No	ClinGen ExAC TOPMed gnomAD
rs765612926 CA257936550	932	P>L		No	ClinGen TOPMed gnomAD
rs765612926 CA389293123	932	P>R		No	ClinGen TOPMed gnomAD
TCGA novel	934	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774532184 CA7137104	935	R>C		No	ClinGen ExAC gnomAD
CA389293177 rs774532184	935	R>G		No	ClinGen ExAC gnomAD
CA7137105 rs533383251	935	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	935	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137106 rs767604457	936	D>N		No	ClinGen ExAC gnomAD
TCGA novel	937	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389293251 rs1164097330	938	P>A		No	ClinGen gnomAD
CA257936587 rs905758273	938	P>L		No	ClinGen TOPMed
CA7137109 rs368950291	939	T>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1423716314 CA389293293	941	D>E		No	ClinGen TOPMed
CA257936594 rs771044984	941	D>H		No	ClinGen TOPMed
CA7137111 rs758361461	941	D>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	944	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389293435 rs1368972775	946	K>R		No	ClinGen gnomAD
CA7137134 rs754738912	951	D>G		No	ClinGen ExAC TOPMed gnomAD
rs780970857 CA7137135	952	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1464931709 CA389293880	954	I>T		No	ClinGen gnomAD
rs1210529781 CA389293866	954	I>V		No	ClinGen TOPMed
rs200069421 CA257937109	960	V>M		No	ClinGen gnomAD
CA389294096 rs1403764493	963	T>A		No	ClinGen gnomAD
CA389294115 rs771536071	963	T>I		No	ClinGen ExAC gnomAD
CA389294089 rs1403764493	963	T>P		No	ClinGen gnomAD
CA7137140 rs771536071	963	T>S		No	ClinGen ExAC gnomAD
rs1345898794 CA389294117	964	L>I		No	ClinGen gnomAD
rs1458883218 CA389294131	964	L>P		No	ClinGen gnomAD
rs772328590 CA7137143	968	S>L		No	ClinGen ExAC TOPMed gnomAD
rs1284523103 CA389294237	969	A>T		No	ClinGen gnomAD
CA7137145 rs761027102	975	S>N		No	ClinGen ExAC gnomAD
CA389294447 rs1288790624	977	D>G		No	ClinGen TOPMed
VAR_037859 rs8017377 CA7137148	978	A>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA389294485 rs1211288948	980	S>P		No	ClinGen gnomAD
CA7137150 rs201369368	981	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389294535 rs181160538	982	P>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs181160538 CA7137152	982	P>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA389294641 rs1156947852	985	S>N		No	ClinGen gnomAD
CA7137154 rs752469901	986	L>M		No	ClinGen ExAC TOPMed gnomAD
CA389294651 rs752469901	986	L>V		No	ClinGen ExAC TOPMed gnomAD
CA7137155 COSM3419753 rs373042156	987	P>L	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs373042156 CA7137156	987	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs146414871 CA7137158	988	N>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs146414871 CA7137157	988	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	989	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1445527904 CA389294716	989	M>V		No	ClinGen gnomAD
CA7137160 rs778420705	990	E>G		No	ClinGen ExAC gnomAD
rs778420705 CA7137159	990	E>V		No	ClinGen ExAC gnomAD
rs934759594 CA257937190	997	E>G		No	ClinGen Ensembl
rs3742518 VAR_037860 CA7137161	997	E>K		No	ClinGen UniProt ExAC dbSNP gnomAD
CA389295062 rs1285850000	999	R>G		No	ClinGen gnomAD
rs1327837666 CA389295075	999	R>M		No	ClinGen gnomAD
CA389295145 rs1370433601	1001	D>N		No	ClinGen gnomAD
rs1220351937 CA389295209	1002	E>A		No	ClinGen gnomAD
COSM1740122 rs200803889 CA7137163	1003	E>D	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs780603993 CA7137162	1003	E>K		No	ClinGen ExAC gnomAD
rs1330114562 CA389295349	1005	R>I		No	ClinGen TOPMed
rs769054523 CA7137164	1006	Q>*		No	ClinGen ExAC gnomAD
rs777003696 CA7137165	1006	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1252819045 CA389295382	1006	Q>P		No	ClinGen gnomAD
CA389295383 rs1252819045	1006	Q>R		No	ClinGen gnomAD
CA389295478 rs1180261017	1009	G>D		No	ClinGen gnomAD
CA389295502 rs1411379756	1010	T>P		No	ClinGen gnomAD
rs762023837 CA7137166	1011	Q>E		No	ClinGen ExAC gnomAD
rs199693660 CA7137168	1013	A>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199693660 CA7137167	1013	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389295598 rs1412553059	1014	A>T		No	ClinGen gnomAD
CA389295613 rs1566487207	1015	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA7137171 rs550900598	1016	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137173 rs760451377	1019	L>P		No	ClinGen ExAC TOPMed gnomAD
rs763821704 CA7137175	1020	D>H		No	ClinGen ExAC gnomAD
CA7137174 rs763821704	1020	D>Y		No	ClinGen ExAC gnomAD
CA389295830 rs1349408747	1021	S>F		No	ClinGen gnomAD
rs1388936658 CA389295855	1022	S>A		No	ClinGen TOPMed
rs778334456 CA7137177	1022	S>L		No	ClinGen ExAC TOPMed gnomAD
rs1427771180 CA389295890	1024	A>T		No	ClinGen TOPMed
rs1219040529 CA389295906	1024	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA7137180 rs535872115	1025	S>T		No	ClinGen 1000Genomes ExAC gnomAD
CA389296051 rs1190616437	1029	V>G		No	ClinGen TOPMed
rs951130609 CA257937247	1029	V>M		No	ClinGen TOPMed
CA389296056 rs747458117	1030	E>*		No	ClinGen ExAC gnomAD
CA7137181 rs747458117	1030	E>Q		No	ClinGen ExAC gnomAD
rs986518721 CA257937254	1031	C>F		No	ClinGen TOPMed
CA7137183 rs375520766	1032	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA257937264 rs375520766	1032	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs755396512 CA7137182	1032	P>S		No	ClinGen ExAC gnomAD
CA7137187 rs773207818	1035	S>L		No	ClinGen ExAC
rs368482072 CA7137189	1038	I>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137191 rs201775736	1040	R>G		No	ClinGen ExAC TOPMed gnomAD
CA7137192 rs763907941	1040	R>Q		No	ClinGen ExAC TOPMed gnomAD
COSM3814648 CA7137190 rs201775736	1040	R>W	breast [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA7137194 rs761411228	1041	C>Y		No	ClinGen ExAC gnomAD
rs1324907843 CA389299526	1044	L>F		No	ClinGen gnomAD
rs546544996 CA7137195	1045	H>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1226576107 CA389299559	1047	P>L		No	ClinGen TOPMed gnomAD
rs757937013 CA7137197	1047	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA7137199 rs752141342	1048	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1566487288 CA389299585	1049	D>E		No	ClinGen Ensembl
CA7137200 rs755490662	1049	D>N		No	ClinGen ExAC TOPMed gnomAD
rs925128322 CA257937333	1050	G>R		No	ClinGen TOPMed
rs936733579 CA257937347	1053	D>G		No	ClinGen TOPMed gnomAD
rs1447806866 CA389299640	1054	I>F		No	ClinGen TOPMed gnomAD
rs1447806866 CA389299638	1054	I>V		No	ClinGen TOPMed gnomAD
CA389299657 rs1594742744	1055	D>A		No	ClinGen Ensembl
CA389299654 rs1248551237	1055	D>N		No	ClinGen gnomAD
rs1186363240 CA389299678	1057	L>V		No	ClinGen gnomAD
CA7137201 rs781725280	1059	G>R		No	ClinGen ExAC gnomAD
TCGA novel	1060	A>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389299712 rs1164608993	1060	A>T		No	ClinGen TOPMed gnomAD
CA389299725 rs756361954	1061	A>P		No	ClinGen ExAC gnomAD
CA7137203 rs756361954	1061	A>T		No	ClinGen ExAC gnomAD
rs1484378633 CA389299743	1062	S>F		No	ClinGen TOPMed
rs1460456611 CA389299745	1063	P>T		No	ClinGen gnomAD
rs1414234981 CA389299762	1064	Y>H		No	ClinGen gnomAD
TCGA novel	1066	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389299810 COSM552868 rs1367891668	1068	P>S	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA7137208 rs746972256	1069	W>*		No	ClinGen ExAC gnomAD
CA7137206 rs771003469	1069	W>R		No	ClinGen ExAC gnomAD
CA7137207 rs774376183	1069	W>S		No	ClinGen ExAC gnomAD
CA7137209 rs768548181	1070	D>E		No	ClinGen ExAC gnomAD
CA389299839 rs1247304389	1070	D>G		No	ClinGen gnomAD
CA7137210 rs776355044	1071	G>R		No	ClinGen ExAC gnomAD
rs1594742784 CA389299878	1073	A>P		No	ClinGen Ensembl
rs764882157 CA7137212	1075	C>F		No	ClinGen ExAC gnomAD
CA389299910 rs1210574471	1076	Q>H		No	ClinGen TOPMed
CA389299913 rs1466166398	1077	Q>*		No	ClinGen TOPMed gnomAD
TCGA novel	1077	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389299911 rs1466166398	1077	Q>K		No	ClinGen TOPMed gnomAD
CA389299918 rs1206614625	1077	Q>P		No	ClinGen gnomAD
rs772918278 CA7137213	1078	V>F		No	ClinGen ExAC gnomAD
rs772918278 CA389299924	1078	V>I		No	ClinGen ExAC gnomAD
rs1230599282 CA389299970	1081	H>Q		No	ClinGen TOPMed
CA7137214 rs762649803	1081	H>R		No	ClinGen ExAC TOPMed gnomAD
rs766007033 CA7137215	1082	L>V		No	ClinGen ExAC gnomAD
CA7137216 rs1555327405	1083	A>T		No	ClinGen Ensembl
rs1159212704 CA389300073	1087	I>V		No	ClinGen gnomAD
CA7137220 rs768137051	1089	S>R		No	ClinGen ExAC gnomAD
CA7137221 rs753065638	1090	N>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1092	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137224 rs777933278	1093	A>P		No	ClinGen ExAC TOPMed gnomAD
CA7137225 rs777933278	1093	A>S		No	ClinGen ExAC TOPMed gnomAD
CA7137223 rs777933278	1093	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1332450351 CA389300273	1093	A>V		No	ClinGen gnomAD
TCGA novel	1095	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1290236798 CA389300361	1097	F>L		No	ClinGen gnomAD
CA257937443 rs1002469716	1098	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1037850729 CA257937453	1101	M>I		No	ClinGen TOPMed
rs768638091 CA389300519	1101	M>R		No	ClinGen ExAC gnomAD
rs768638091 CA7137228	1101	M>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA389300533 rs1260061434	1102	D>Y		No	ClinGen gnomAD
rs978928175 CA257937468	1103	S>C		No	ClinGen TOPMed gnomAD
CA257937457 rs978928175	1103	S>Y		No	ClinGen TOPMed gnomAD
CA389300623 rs1249413610	1105	R>G		No	ClinGen TOPMed
CA257937471 rs926094830	1105	R>K		No	ClinGen TOPMed
rs1201900439 CA389300646	1106	D>N		No	ClinGen gnomAD
CA7137229 rs374795039	1106	D>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137230 rs747966365	1107	A>V		No	ClinGen ExAC gnomAD
rs912019927 CA257937475	1108	I>L		No	ClinGen TOPMed gnomAD
CA389300769 rs1218754019	1110	D>Y		No	ClinGen TOPMed
rs575552934 CA7137232	1111	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
rs575552934 CA389300811	1111	Y>F		No	ClinGen 1000Genomes ExAC gnomAD
CA257937480 rs1025809274	1111	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1378657283 CA389300890	1113	A>V		No	ClinGen gnomAD
rs1467903297 CA389300918	1114	L>P		No	ClinGen gnomAD
CA7137234 rs770679930	1115	V>M		No	ClinGen ExAC TOPMed gnomAD
CA389300960 rs1375092883	1116	G>D		No	ClinGen gnomAD
rs1270672055 CA389300978	1117	P>H		No	ClinGen gnomAD
rs370097904 CA7137235	1120	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1310053404 CA389301077	1120	S>R		No	ClinGen gnomAD
TCGA novel	1122	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137236 rs372429210	1124	Q>R		No	ClinGen ESP ExAC gnomAD
CA389301318 rs1410770300	1126	P>L		No	ClinGen TOPMed
rs766882927 CA7137237	1126	P>S		No	ClinGen ExAC gnomAD
rs1367536972 CA389301333	1127	D>G		No	ClinGen TOPMed
rs753252556 CA7137238	1128	W>R		No	ClinGen ExAC gnomAD
rs1235175219 CA389301397	1129	Q>H		No	ClinGen TOPMed gnomAD
rs761047114 CA7137239	1129	Q>K		No	ClinGen ExAC gnomAD
rs1277987028 CA389301552	1133	E>A		No	ClinGen TOPMed gnomAD
CA7137241 rs754180089	1136	E>G		No	ClinGen ExAC gnomAD
COSM1188790 CA7137240 rs764543033	1136	E>K	lung [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1479377888 CA389301682	1137	A>T		No	ClinGen gnomAD
CA257937516 rs921155963	1141	L>Q		No	ClinGen Ensembl
rs1594742928 CA389301821	1142	K>N		No	ClinGen Ensembl
rs1435373180 CA389301824	1143	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs779092068 CA7137243	1143	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA7137244 rs750586325	1144	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1368877167 CA389301899	1147	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA7137245 rs758476040	1147	S>P		No	ClinGen ExAC TOPMed gnomAD
rs1594742947 CA389302030	1151	L>M		No	ClinGen Ensembl
rs1294141363 CA389302065	1152	M>I		No	ClinGen gnomAD
rs779954505 CA7137246	1152	M>K		No	ClinGen ExAC TOPMed gnomAD
rs779954505 CA389302057	1152	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1478003248 CA389302084	1153	A>G		No	ClinGen gnomAD
CA389302077 rs1594742962	1153	A>S		No	ClinGen Ensembl
CA389302089 rs1478003248	1153	A>V		No	ClinGen gnomAD
CA389302124 rs1369795736	1154	P>L		No	ClinGen gnomAD
rs1388492774 CA389302172	1156	S>F		No	ClinGen gnomAD
rs200952720 CA7137247	1157	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1276336110 CA389302241	1159	P>S		No	ClinGen gnomAD
rs777661158 CA7137249	1161	R>C	Variant assessed as Somatic; 4.798e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs777661158 CA389302302	1161	R>G		No	ClinGen ExAC TOPMed gnomAD
rs749094268 CA7137250	1161	R>H		No	ClinGen ExAC TOPMed gnomAD
CA389302373 rs1330955302	1164	V>M		No	ClinGen TOPMed
CA7137253 rs759198850	1166	V>M		No	ClinGen ExAC gnomAD
rs774816011 CA7137255	1169	V>M		No	ClinGen ExAC TOPMed gnomAD
rs764502613 CA7137257	1172	T>K		No	ClinGen ExAC TOPMed gnomAD
COSM1135558 rs764502613 CA389302591	1172	T>M	kidney Variant assessed as Somatic; 4.663e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1173	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389302646 rs1165717119	1175	L>H		No	ClinGen gnomAD
CA7137260 rs765518334	1181	G>E		No	ClinGen ExAC TOPMed gnomAD
CA389302937 rs376021092	1184	H>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137262 rs376021092	1184	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs574649411 CA389302951	1185	P>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA TOPMed gnomAD
rs574649411 CA257937567	1185	P>L		No	ClinGen 1000Genomes TOPMed gnomAD
rs1454655839 CA389302948	1185	P>S		No	ClinGen Ensembl
CA389302945 rs1454655839	1185	P>T		No	ClinGen Ensembl
rs1386059842 CA389302962	1186	I>V		No	ClinGen gnomAD
CA7137263 rs763317583	1187	A>S		No	ClinGen ExAC TOPMed gnomAD
rs1359575549 CA389303002	1187	A>V		No	ClinGen TOPMed gnomAD
rs1213668544 CA389303053	1189	T>S		No	ClinGen gnomAD
CA7137264 rs751558441	1192	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA257937573 rs982492930	1192	P>S		No	ClinGen TOPMed
CA7137267 rs749183752	1195	P>R		No	ClinGen ExAC
CA7137266 rs777841839	1195	P>S		No	ClinGen ExAC gnomAD
CA389303253 rs1465707202	1196	D>G		No	ClinGen TOPMed gnomAD
rs1465707202 CA389303250	1196	D>V		No	ClinGen TOPMed gnomAD
rs1401905902 CA389303315	1198	E>G		No	ClinGen TOPMed gnomAD
rs766822337 CA7137270	1202	P>S		No	ClinGen ExAC TOPMed gnomAD
CA389303531 rs369114620	1205	G>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137271 rs369114620	1205	G>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137272 rs775107719	1206	G>R		No	ClinGen ExAC gnomAD
rs1416151635 COSM1188791 CA389303563	1206	G>V	lung [Cosmic]	No	ClinGen cosmic curated gnomAD
rs746486708 CA389303601	1207	D>E		No	ClinGen ExAC TOPMed gnomAD
rs1022604616 CA257937601	1209	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA7137274 rs768152222	1210	Y>C		No	ClinGen ExAC gnomAD
rs1417104418 CA389303683	1211	A>D		No	ClinGen TOPMed gnomAD
rs929464277 CA257937605	1214	W>L		No	ClinGen TOPMed gnomAD
CA7137275 rs777127282	1215	A>T		No	ClinGen ExAC gnomAD
CA389303738 rs1566487599	1216	L>F		No	ClinGen Ensembl
TCGA novel	1217	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs762266975 CA7137276	1217	K>R		No	ClinGen ExAC gnomAD
rs1047918223 CA257937615	1218	H>Y		No	ClinGen TOPMed
rs376334971 CA7137278	1221	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137279 rs763274425 COSM1470664	1221	R>H	prostate [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA389303830 rs763274425	1221	R>P		No	ClinGen ExAC TOPMed gnomAD
rs1007988240 CA257937618	1223	I>T		No	ClinGen TOPMed gnomAD
rs1267711099 CA389303869	1223	I>V		No	ClinGen gnomAD
CA389303926 rs1566487628	1226	T>A		No	ClinGen Ensembl
CA7137282 rs751722096	1226	T>S		No	ClinGen ExAC gnomAD
rs755029945 CA257937624	1227	P>L		No	ClinGen ExAC TOPMed gnomAD
rs755029945 CA7137283	1227	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1167957806 CA389303979	1228	V>M		No	ClinGen TOPMed
CA389304016 rs1211175026	1229	V>A		No	ClinGen gnomAD
rs757212524 CA7137286	1231	D>H		No	ClinGen ExAC gnomAD
CA389304079 rs1187463482	1232	L>H		No	ClinGen gnomAD
CA7137287 rs778901743	1233	S>C		No	ClinGen ExAC gnomAD
rs1473610709 CA389304190	1236	S>F		No	ClinGen gnomAD
rs1391536662 CA389304207	1237	R>P		No	ClinGen TOPMed
CA257937639 rs996683229	1237	R>W		No	ClinGen TOPMed gnomAD
CA7137288 rs144623810	1238	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA257937661 rs377707810	1240	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7137289 rs138467096	1240	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7137290 rs377707810	1240	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs982221075 CA257937667	1242	P>S		No	ClinGen TOPMed
CA7137292 rs768081201	1243	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1350631470 CA389304361	1244	V>M		No	ClinGen gnomAD
CA7137295 rs368016452	1245	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs375519821 CA7137293	1245	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137297 rs531016898	1248	R>C		No	ClinGen 1000Genomes ExAC gnomAD
rs542139168 CA7137298	1248	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	1248	R>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759768969 CA7137300	1250	V>D		No	ClinGen ExAC gnomAD
rs774445013 CA7137299	1250	V>I		No	ClinGen ExAC TOPMed gnomAD
rs767728039 CA7137301	1253	A>S		No	ClinGen ExAC gnomAD
TCGA novel	1253	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137302 rs752803644	1257	R>*		No	ClinGen ExAC gnomAD
TCGA novel	1257	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389304757 rs1396822878	1258	W>*		No	ClinGen TOPMed
CA389304770 rs1231127749	1258	W>C		No	ClinGen gnomAD
rs761883672 CA7137303	1261	L>S		No	ClinGen ExAC gnomAD
rs777966712 CA257937706	1263	Q>R		No	ClinGen Ensembl
rs1307157884 CA389304932	1264	D>E		No	ClinGen TOPMed
CA389304928 rs1403155011	1264	D>V		No	ClinGen TOPMed gnomAD
CA257937710 rs753256579	1265	K>N		No	ClinGen Ensembl
CA389305073 rs1191670919	1267	K>M		No	ClinGen gnomAD
rs765263797 CA7137304	1268	R>G		No	ClinGen ExAC gnomAD
CA7137305 rs750315913	1268	R>K		No	ClinGen ExAC TOPMed gnomAD
CA389305124 rs1172636437	1269	A>D		No	ClinGen gnomAD
TCGA novel	1269	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751192692 CA7137308	1274	L>F		No	ClinGen ExAC
TCGA novel	1274	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1472146683 CA389305296	1275	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA389305353 rs1277118098	1276	Q>*		No	ClinGen gnomAD
CA389305407 rs778158529	1277	G>D		No	ClinGen ExAC gnomAD
rs371855060 CA7137312	1277	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137313 rs778158529	1277	G>V		No	ClinGen ExAC gnomAD
rs759726589 CA7137318	1281	E>K		No	ClinGen ExAC TOPMed gnomAD
CA389305569 rs1594743213	1282	N>T		No	ClinGen Ensembl
CA7137319 rs374730919	1283	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs775781760 CA7137320	1283	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs775781760 CA257937741	1283	R>L		No	ClinGen ExAC TOPMed gnomAD
CA7137323 rs750357738	1286	T>I		No	ClinGen ExAC gnomAD
CA389305695 rs1594743226	1286	T>P		No	ClinGen Ensembl
rs766132981 CA389305761	1288	A>S		No	ClinGen ExAC TOPMed gnomAD
rs766132981 CA7137325	1288	A>T		No	ClinGen ExAC TOPMed gnomAD
CA7137326 rs751334932	1288	A>V		No	ClinGen ExAC TOPMed gnomAD
CA389305777 rs1298862850	1289	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA7137328 rs780807825	1290	S>F		No	ClinGen ExAC TOPMed gnomAD
CA7137329 rs752292028	1291	M>I		No	ClinGen ExAC gnomAD
CA389305847 rs1269811568	1292	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA7137331 rs755628226	1293	R>C		No	ClinGen ExAC TOPMed gnomAD
CA7137330 rs755628226	1293	R>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1293	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389305962 rs1211641539	1296	Q>R		No	ClinGen gnomAD
rs749786689 CA7137332	1297	V>L		No	ClinGen ExAC gnomAD
rs189972799 CA7137333	1299	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1013940453 CA257937774	1301	F>L		No	ClinGen Ensembl
rs1594743260 CA389306136	1303	D>A		No	ClinGen Ensembl
rs772483093 CA7137336	1306	T>M		No	ClinGen ExAC TOPMed gnomAD
CA7137339 rs768878706 COSM955077	1308	V>I	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA389306274 rs1450372895	1309	C>S		No	ClinGen TOPMed
CA389306351 rs1594743286	1311	H>Q		No	ClinGen Ensembl
rs758082819 CA7137340	1313	S>L		No	ClinGen ExAC gnomAD
rs758082819 CA389306395	1313	S>W		No	ClinGen ExAC gnomAD
CA257937791 rs746836385	1315	Y>H		No	ClinGen Ensembl
rs768509689 CA257937796	1316	C>Y		No	ClinGen TOPMed gnomAD
rs766332432 CA7137342	1319	R>C		No	ClinGen ExAC TOPMed gnomAD
CA257937805 rs776363411	1319	R>H		No	ClinGen ExAC TOPMed gnomAD
CA7137343 COSM1515302 rs776363411	1319	R>L	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1322	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389306612 rs1291572216	1324	C>F		No	ClinGen gnomAD
TCGA novel	1325	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389306736 rs1594743315	1330	Y>C		No	ClinGen Ensembl
rs1261230206 CA389306808	1333	S>L		No	ClinGen gnomAD
rs1594743328 CA389306830	1334	P>L		No	ClinGen Ensembl
CA389306880 rs763566221	1336	S>R		No	ClinGen ExAC gnomAD
rs371735612 CA7137349	1337	P>S	Variant assessed as Somatic; 9.289e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs757771394 CA7137350	1338	P>A		No	ClinGen ExAC TOPMed gnomAD
CA389306909 rs757771394	1338	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1458477475 CA389306985	1341	L>H		No	ClinGen TOPMed
CA389306991 rs1458477475	1341	L>P		No	ClinGen TOPMed
CA7137353 rs746309161	1343	F>L		No	ClinGen ExAC gnomAD
rs371099138 CA257937830	1347	P>S		No	ClinGen Ensembl
rs538061448 CA7137354 COSM469871	1349	T>M	kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1403335446 CA389307148	1349	T>S		No	ClinGen gnomAD
CA389307161 rs1182065331	1350	P>A		No	ClinGen gnomAD
rs1367580334 CA389307173	1351	T>A		No	ClinGen TOPMed gnomAD
rs1464448323 CA389307188	1351	T>I		No	ClinGen TOPMed
CA7137356 rs747284202	1352	Y>F		No	ClinGen ExAC gnomAD
TCGA novel	1352	Y>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1594743381 CA389307252	1354	H>P		No	ClinGen Ensembl
CA389307331 rs1318611091	1358	V>M		No	ClinGen TOPMed gnomAD
rs748243389 CA257937848	1359	A>G		No	ClinGen ExAC TOPMed gnomAD
rs748243389 CA7137359	1359	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1363903002 CA389307399	1361	G>D		No	ClinGen TOPMed
rs375921086 CA7137361	1361	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs775248149 CA7137364	1364	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA7137365 rs760361213	1364	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs763798922 CA389307475	1365	F>I		No	ClinGen ExAC TOPMed gnomAD
CA7137366 rs763798922	1365	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1566487942 CA389307482	1365	F>S		No	ClinGen Ensembl
rs1333950974 CA389307499	1366	G>A		No	ClinGen TOPMed
CA7137367 rs753348018	1366	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1417909153 CA389307508	1367	Q>*		No	ClinGen gnomAD
rs1413068964 CA389307513	1367	Q>R		No	ClinGen TOPMed
rs756807669 CA7137368	1369	P>S		No	ClinGen ExAC TOPMed gnomAD
CA389307565 rs1436957771	1371	P>L		No	ClinGen gnomAD
CA389307586 rs1594743421	1373	V>G		No	ClinGen Ensembl
TCGA novel	1375	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1172024548 CA389307605	1375	L>V		No	ClinGen gnomAD
rs1174897194 CA389307623	1376	T>I		No	ClinGen TOPMed
rs1430520110 CA389307644	1378	C>Y		No	ClinGen TOPMed gnomAD
rs1190557127 CA389307651	1379	N>D		No	ClinGen TOPMed
rs758950621 CA7137371	1379	N>S		No	ClinGen ExAC gnomAD
rs1306184420 CA389307715	1384	L>F		No	ClinGen gnomAD
CA7137374 rs755209903	1387	E>K		No	ClinGen ExAC gnomAD
rs568146265 CA7137375	1391	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1329768082 CA389307868	1391	L>H		No	ClinGen gnomAD
CA7137376 rs748250487	1392	W>*		No	ClinGen ExAC gnomAD
rs951006953 CA257937898	1394	A>S		No	ClinGen TOPMed
rs769950057 CA7137377	1395	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA257937901 rs773467592	1395	R>W		No	ClinGen gnomAD
CA7137378 rs777784917	1396	G>V		No	ClinGen ExAC gnomAD
rs1192101541 CA389307951	1397	F>L		No	ClinGen gnomAD
CA389307986 rs1294809348	1399	S>F		No	ClinGen TOPMed
CA7137379 rs374418928	1404	P>L		No	ClinGen 1000Genomes ExAC gnomAD
rs1394728713 CA389308073	1404	P>S		No	ClinGen gnomAD
CA7137380 rs771970441	1405	L>I		No	ClinGen ExAC gnomAD
CA389308135 rs1461494086	1407	H>P		No	ClinGen gnomAD
CA389308139 rs1461494086	1407	H>R		No	ClinGen gnomAD
CA7137382 rs760506948	1408	P>L		No	ClinGen ExAC TOPMed gnomAD
rs768279369 CA7137383	1413	Y>H		No	ClinGen ExAC gnomAD
rs1442856086 CA389308273	1414	I>V		No	ClinGen TOPMed gnomAD
rs1301037438 CA389308301	1415	I>T		No	ClinGen gnomAD
CA389308321 rs1369939998	1416	S>Y		No	ClinGen gnomAD
rs1214868529 CA389308332	1417	L>F		No	ClinGen gnomAD
rs1445355696 CA389308355	1418	T>I		No	ClinGen TOPMed
CA389308344 rs1594743494	1418	T>P		No	ClinGen Ensembl
rs376235359 CA257937919	1419	S>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137385 rs376235359	1419	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA389308371 rs1594743504	1419	S>P		No	ClinGen Ensembl
rs764887892 CA7137386	1420	G>D		No	ClinGen ExAC gnomAD
rs1313842556 CA389308469	1424	L>F		No	ClinGen TOPMed
CA7137388 rs375065906	1425	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs752053594 CA7137390	1426	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1433867727 CA389308556	1428	Y>C		No	ClinGen Ensembl
rs1317282176 CA389308566	1429	R>*		No	ClinGen gnomAD
CA389308568 COSM955081 rs1252835429	1429	R>Q	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs202118734 CA7137392	1433	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7137393 rs752986848	1433	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
COSM163044 rs202118734 CA7137391	1433	R>W	breast [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA389308625 rs1428024988	1434	G>C		No	ClinGen gnomAD
CA389308621 rs1428024988	1434	G>S		No	ClinGen gnomAD
rs1420081006 CA389308644	1435	S>F		No	ClinGen TOPMed gnomAD
TCGA novel	1436	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749370580 CA7137397	1438	A>S		No	ClinGen ExAC gnomAD
rs779983688 CA7137399	1439	V>E		No	ClinGen ExAC
rs746856903 CA7137400	1443	T>I		No	ClinGen ExAC gnomAD
rs746856903 CA389308743	1443	T>N		No	ClinGen ExAC gnomAD
rs1359380799 CA389308771	1446	K>M		No	ClinGen gnomAD
rs1381185758 CA389308786	1448	G>A		No	ClinGen gnomAD
rs1196783032 CA389308784	1448	G>S		No	ClinGen gnomAD
CA389308797 rs1254996588	1450	Q>*		No	ClinGen gnomAD
CA389308829 rs769561880	1452	G>D		No	ClinGen ExAC TOPMed gnomAD
rs761563648 CA7137403	1452	G>S		No	ClinGen ExAC gnomAD
CA7137404 rs769561880	1452	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1317901011 CA389308872	1455	W>*		No	ClinGen gnomAD
CA389308883 rs1218333404	1456	W>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1240600586 CA389308893	1456	W>C		No	ClinGen gnomAD
CA7137405 rs143110133	1458	L>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA389308950 rs1188878801	1459	P>L		No	ClinGen gnomAD
TCGA novel	1459	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137406 rs762564564	1460	K>E		No	ClinGen ExAC gnomAD
rs765919110 CA7137407	1460	K>R		No	ClinGen ExAC gnomAD
CA389309031 rs1162723295	1463	P>A		No	ClinGen gnomAD
CA389309045 rs1385312926	1463	P>L		No	ClinGen gnomAD
rs752136494 CA7137408	1464	A>V		No	ClinGen ExAC gnomAD
rs1409541674 CA389309103	1467	V>M		No	ClinGen TOPMed
CA257937999 rs1009865264	1469	P>L		No	ClinGen TOPMed
rs1452656617 CA389309159	1469	P>S		No	ClinGen gnomAD
rs752973891 CA7137411	1470	H>Y		No	ClinGen ExAC gnomAD
TCGA novel	1471	A>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137412 rs756426464	1471	A>G		No	ClinGen ExAC gnomAD
CA389309198 rs1356831029	1471	A>T		No	ClinGen gnomAD
CA389309244 rs1374620697	1472	M>I		No	ClinGen gnomAD
rs777963123 CA7137413	1472	M>V		No	ClinGen ExAC gnomAD
COSM3690049 rs199709655 CA7137414	1476	P>L	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs1042301209 CA257938009	1476	P>T		No	ClinGen TOPMed
CA7137415 rs544959631	1477	N>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1003361620 CA257938021	1477	N>Y		No	ClinGen TOPMed gnomAD
CA7137417 CA389309368 rs778926553	1478	L>F		No	ClinGen ExAC gnomAD
rs1282672590 CA389309375	1479	L>M		No	ClinGen gnomAD
CA389309395 rs1484736195	1480	A>T		No	ClinGen gnomAD
CA389309427 rs1236858889	1481	L>S		No	ClinGen gnomAD
CA389309452 rs1171815729	1482	Q>R		No	ClinGen TOPMed gnomAD
rs781103975 CA7137419	1484	S>N		No	ClinGen ExAC TOPMed gnomAD
CA257938030 rs558626844	1487	T>N		No	ClinGen 1000Genomes
rs1594743662 CA389309538	1487	T>P		No	ClinGen Ensembl
rs747882266 CA7137420	1489	A>S		No	ClinGen ExAC gnomAD
CA7137424 rs770589936	1490	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs773713380 CA7137425	1491	I>L		No	ClinGen ExAC TOPMed gnomAD
CA389309648 rs1432349637	1492	I>V		No	ClinGen gnomAD
rs377683697 CA7137426 CA257938047	1494	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1373075048 CA389309789	1498	G>E		No	ClinGen gnomAD
rs761045897 CA7137429 CA389309780	1498	G>R		No	ClinGen ExAC gnomAD
rs754093809 CA7137431	1500	K>I		No	ClinGen ExAC gnomAD
CA7137434 rs750461863	1503	G>V		No	ClinGen ExAC gnomAD
CA389309914 rs1367469425	1504	S>F		No	ClinGen TOPMed
rs1439629034 CA389309905	1504	S>P		No	ClinGen TOPMed gnomAD
CA7137435 rs367917534	1506	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137436 rs367917534	1506	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA389309963 rs1438887159	1508	S>G		No	ClinGen gnomAD
CA389310000 rs756003908	1509	S>F		No	ClinGen ExAC TOPMed gnomAD
CA7137438 rs756003908	1509	S>Y		No	ClinGen ExAC TOPMed gnomAD
CA7137440 rs748999477	1512	N>T		No	ClinGen ExAC gnomAD
rs1295585274 CA389310081	1513	S>L		No	ClinGen Ensembl
CA7137441 rs770677942	1515	S>G		No	ClinGen ExAC gnomAD
rs1411099883 CA389310128	1515	S>R		No	ClinGen gnomAD
CA7137445 rs775869293	1517	D>G		No	ClinGen ExAC gnomAD
CA7137444 rs767958088	1517	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	1519	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137446 rs761134037	1519	E>K		No	ClinGen ExAC gnomAD
CA7137447 rs764468087	1521	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1270977150 CA389310288	1522	L>Q		No	ClinGen gnomAD
rs200445194 CA7137448	1522	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137451 COSM955082 rs750601148	1523	L>F	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1566488242 CA389310300	1523	L>R		No	ClinGen Ensembl
CA7137453 rs766440814	1524	M>I		No	ClinGen ExAC gnomAD
rs758411500 CA7137452	1524	M>T		No	ClinGen ExAC TOPMed gnomAD
rs368652110 CA389310363	1526	K>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137454 rs368652110	1526	K>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA389310399 rs1207780570	1528	D>N		No	ClinGen TOPMed
CA389310436 rs1594743772	1529	K>T		No	ClinGen Ensembl
CA7137457 rs753683004	1530	K>Q		No	ClinGen ExAC gnomAD
CA389310503 rs1476128648	1532	R>K		No	ClinGen gnomAD
CA389310532 rs1165606503	1533	V>A		No	ClinGen gnomAD
rs778448529 CA7137459	1534	W>S		No	ClinGen ExAC TOPMed gnomAD
CA389310611 rs1167734594	1537	P>L		No	ClinGen TOPMed gnomAD
CA389310616 rs1167734594	1537	P>R		No	ClinGen TOPMed gnomAD
rs560584806 CA257938101	1538	T>A		No	ClinGen 1000Genomes TOPMed gnomAD
COSM955084 rs1386496520 CA389310637	1538	T>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA7137464 rs769144777	1541	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA7137463 rs532149352	1541	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs112761553 CA257938112	1542	R>K		No	ClinGen Ensembl
TCGA novel	1543	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1335539420 CA389310736	1543	D>Y		No	ClinGen gnomAD
CA7137467 rs770129632	1547	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs552174983 CA7137468	1550	D>H		No	ClinGen 1000Genomes ExAC gnomAD
CA389310904 rs1261923874	1551	I>T		No	ClinGen gnomAD
rs17103672 VAR_037861 CA7137469	1551	I>V		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA7137472 rs751661409	1555	A>T		No	ClinGen ExAC TOPMed gnomAD
rs760763027 CA7137473	1555	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA389311026 rs1159558262	1557	Q>*		No	ClinGen gnomAD
rs764115157 CA7137475	1559	P>A		No	ClinGen ExAC TOPMed gnomAD
rs764115157 CA7137474	1559	P>S		No	ClinGen ExAC TOPMed gnomAD
CA7137477 rs778733327	1560	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs750069211 CA7137478	1561	E>D		No	ClinGen ExAC gnomAD
rs1416629255 CA389311127	1561	E>K		No	ClinGen TOPMed gnomAD
rs758049675 CA7137479	1563	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	1564	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389311214 rs1187340946	1564	K>R		No	ClinGen TOPMed
TCGA novel	1564	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779603320 CA7137480	1565	K>*		No	ClinGen ExAC gnomAD
CA389311281 rs1261134700	1565	K>N		No	ClinGen TOPMed gnomAD
CA7137481 rs746506554	1567	R>C		No	ClinGen ExAC TOPMed gnomAD
COSM955086 rs769142864 CA257938155	1567	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs769142864 CA257938158	1567	R>L		No	ClinGen TOPMed gnomAD
CA389311422 rs1485729905	1570	G>E		No	ClinGen gnomAD
rs1254746125 CA389311459	1571	W>*		No	ClinGen gnomAD
rs531468217 CA7137484	1573	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1365967174 CA389311559	1576	Q>H		No	ClinGen gnomAD
CA389311568 rs1566488365	1577	E>Q		No	ClinGen Ensembl
CA7137486 rs773603303	1581	D>E		No	ClinGen ExAC TOPMed gnomAD
rs1003476713 CA257938168	1581	D>V		No	ClinGen TOPMed
rs771182311 CA7137488	1582	Y>F		No	ClinGen ExAC gnomAD
CA389311701 rs1178823625	1583	C>R		No	ClinGen TOPMed gnomAD
rs774630777 CA257938178	1583	C>W		No	ClinGen ExAC gnomAD
TCGA novel	1584	R>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1296483420 CA389311811	1587	L>F		No	ClinGen TOPMed
CA389311817 rs1395451022	1588	F>L		No	ClinGen gnomAD
rs764692390 CA7137492	1591	P>A		No	ClinGen ExAC TOPMed gnomAD
rs764692390 CA389311889	1591	P>T		No	ClinGen ExAC TOPMed gnomAD
CA7137493 rs199717611	1592	R>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137494 rs545743634	1592	R>Q		No	ClinGen ExAC gnomAD
CA389311956 rs1212537633	1595	I>T		No	ClinGen gnomAD
rs533737076 CA7137498	1597	S>R		No	ClinGen 1000Genomes ExAC gnomAD
rs749999800 CA7137499	1598	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA7137500 rs780632124	1599	L>F		No	ClinGen ExAC gnomAD
rs1436464254 CA389312149	1604	S>A		No	ClinGen gnomAD
rs756612498 CA7137502	1605	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1172003209 CA389312198	1606	W>*		No	ClinGen gnomAD
TCGA novel	1607	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1608	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389312274 rs1594743933	1610	S>A		No	ClinGen Ensembl
rs758029753 CA257938216	1610	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1594743939 CA389312294	1611	T>P		No	ClinGen Ensembl
TCGA novel	1612	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM432973 rs746050976 CA7137507	1615	S>L	Variant assessed as Somatic; 4.643e-05 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA389312382 rs746050976	1615	S>W		No	ClinGen ExAC TOPMed gnomAD
CA7137509 rs775691938	1616	N>S		No	ClinGen ExAC
CA389312446 rs1225792345	1619	I>F		No	ClinGen gnomAD
rs765204240 CA7137511	1620	E>K		No	ClinGen ExAC gnomAD
rs765204240 CA389312476	1620	E>Q		No	ClinGen ExAC gnomAD
rs1594743966 CA389312511	1621	V>G		No	ClinGen Ensembl
CA389312503 rs1328089429	1621	V>L		No	ClinGen TOPMed gnomAD
rs772962674 CA7137512	1622	V>M		No	ClinGen ExAC gnomAD
rs762806768 CA7137513	1624	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1341645747 CA389312635	1626	T>I		No	ClinGen TOPMed
rs369343954 CA389312640	1627	I>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7137516 rs369343954	1627	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel CA389312699 rs779512856	1628	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC TOPMed gnomAD NCI-TCGA
CA7137518 rs752248841	1630	E>K		No	ClinGen ExAC gnomAD
rs752248841 CA389312723	1630	E>Q		No	ClinGen ExAC gnomAD
CA7137520 rs189237524	1636	L>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1638	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1638	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1429231617 CA389312986	1639	A>G		No	ClinGen gnomAD
CA257938248 rs868474525	1641	P>S		No	ClinGen gnomAD
rs868474525 CA389313027	1641	P>T		No	ClinGen gnomAD
TCGA novel	1643	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137522 rs757731670	1643	T>N		No	ClinGen ExAC gnomAD
rs1394955245 CA389313102	1644	R>K		No	ClinGen TOPMed gnomAD
CA389313108 rs1394955245	1644	R>T		No	ClinGen TOPMed gnomAD
rs746145131 CA7137524	1645	W>*		No	ClinGen ExAC gnomAD
rs1594744011 CA389313150	1646	V>G		No	ClinGen Ensembl
rs1366412437 CA389313139	1646	V>M		No	ClinGen gnomAD
rs913013921 CA257938259	1648	A>G		No	ClinGen TOPMed
rs913013921 CA389313180	1648	A>V		No	ClinGen TOPMed
CA7137526 rs368787980	1649	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1040074365 CA257938265	1650	P>S		No	ClinGen Ensembl
rs191929972 CA7137529	1653	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs191929972 CA389313272	1653	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1307765782 CA389313297	1654	Y>C		No	ClinGen Ensembl
CA7137532 rs766210479	1654	Y>H		No	ClinGen ExAC
CA7137533 rs201409522	1657	T>M	Variant assessed as Somatic; 4.642e-05 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs767145009 CA7137535	1658	A>T		No	ClinGen ExAC gnomAD
rs752235850 CA7137536	1663	L>M		No	ClinGen ExAC
rs1261198000 CA389313636	1671	W>*		No	ClinGen gnomAD
rs763472495 CA7137538	1671	W>C		No	ClinGen ExAC TOPMed gnomAD
CA389313638 rs1261198000	1671	W>S		No	ClinGen gnomAD
CA389313738 rs1418431453	1676	R>K		No	ClinGen gnomAD
CA389313756 rs1462836405	1677	L>V		No	ClinGen TOPMed gnomAD
CA7137540 rs757821591	1678	E>G		No	ClinGen ExAC TOPMed gnomAD
CA389313809 rs1275209338	1679	A>V		No	ClinGen TOPMed
rs1290260614 CA389313828	1680	A>G		No	ClinGen gnomAD
CA389313848 rs1594744068	1681	Q>P		No	ClinGen Ensembl
CA389313879 rs1337793954	1682	G>E		No	ClinGen gnomAD
rs540426935 CA7137541	1684	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137544 rs758775630	1687	R>L		No	ClinGen ExAC TOPMed gnomAD
CA7137543 COSM3814650 rs758775630	1687	R>Q	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA7137542 rs528567243	1687	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1227071805 CA389313997	1688	H>Y		No	ClinGen gnomAD
rs532821287 CA7137546	1689	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs781109621 CA7137547	1690	L>I		No	ClinGen ExAC gnomAD
rs1328968980 CA389314060	1690	L>R		No	ClinGen TOPMed
rs1385680659 CA389314187	1696	A>S		No	ClinGen TOPMed
rs759341474 CA7137551	1700	Q>H		No	ClinGen ExAC gnomAD
rs771697081 CA7137552	1701	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1411754978 CA389314234	1702	A>V		No	ClinGen TOPMed
rs376539582 CA7137554	1703	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs376539582 CA7137553	1703	S>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA257938332 rs969384970	1705	S>N		No	ClinGen gnomAD
CA389314274 rs969384970	1705	S>T		No	ClinGen gnomAD
CA389314292 rs765850035	1706	R>P		No	ClinGen ExAC TOPMed gnomAD
rs765850035 CA7137558	1706	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA7137557 rs762480375	1706	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA389314323 rs1446536675	1708	L>F		No	ClinGen gnomAD
CA389314340 rs1254950087	1709	Q>*		No	ClinGen TOPMed
rs1284063044 CA389314376	1710	F>C		No	ClinGen gnomAD
CA7137560 rs758861483	1711	P>L		No	ClinGen ExAC TOPMed gnomAD
rs750891833 CA7137559	1711	P>S		No	ClinGen ExAC gnomAD
rs375430981 CA257938342	1712	C>F		No	ClinGen Ensembl
rs374015737 CA7137561	1713	L>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137563 rs755124186	1714	T>A		No	ClinGen ExAC gnomAD
CA7137565 rs367836472	1714	T>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137564 rs367836472	1714	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs912950166 CA389314527	1717	G>R		No	ClinGen gnomAD
rs912950166 CA257938356	1717	G>W		No	ClinGen gnomAD
CA7137568 rs374589341	1718	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA257938368 rs374589341	1718	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1566488651 CA389314546	1718	A>V		No	ClinGen Ensembl
rs1173858155 CA389314628	1724	R>K		No	ClinGen gnomAD
rs771924412 CA7137569	1725	A>D		No	ClinGen ExAC gnomAD
rs775128958 CA7137570	1726	L>P		No	ClinGen ExAC gnomAD
CA389316360 rs1441233330	1727	K>R		No	ClinGen TOPMed
TCGA novel	1729	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1732	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1376624354 CA389316460	1733	H>D		No	ClinGen gnomAD
rs367617198 CA257938386	1733	H>Q		No	ClinGen Ensembl
rs1441991614 CA389316463	1733	H>R		No	ClinGen gnomAD
CA389316466 rs1305827739	1734	G>R		No	ClinGen gnomAD
TCGA novel	1738	A>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137575 rs200693824	1738	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1453092400 CA389316514	1740	S>F		No	ClinGen TOPMed
CA389316525 rs1594744198	1741	L>Q		No	ClinGen Ensembl
TCGA novel	1742	P>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389316575 rs1316963054	1744	L>P		No	ClinGen TOPMed gnomAD
CA7137579 rs751865948	1745	H>Y		No	ClinGen ExAC gnomAD
rs1248053885 CA389316602	1746	L>V		No	ClinGen gnomAD
rs1171535380 CA389316613	1747	A>T		No	ClinGen gnomAD
CA389316621 rs1419567601	1747	A>V		No	ClinGen gnomAD
CA7137581 rs767647423	1749	R>T		No	ClinGen ExAC gnomAD
CA389316684 rs1400045513	1751	S>A		No	ClinGen gnomAD
COSM698063 CA7137583 rs756219353	1754	D>Y	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1005390562 CA257938409	1755	A>V		No	ClinGen TOPMed
CA389316771 rs1436003325	1756	T>I		No	ClinGen gnomAD
CA7137585 rs777988787	1757	P>L		No	ClinGen ExAC TOPMed gnomAD
CA389316809 rs1255998637	1758	F>L		No	ClinGen gnomAD
rs1050695479 CA257938420	1759	K>Q		No	ClinGen Ensembl
rs901859719 CA257938423	1761	L>V		No	ClinGen TOPMed
CA7137587 rs779970498	1762	T>S		No	ClinGen ExAC gnomAD
rs768427936 CA7137589	1763	G>R		No	ClinGen ExAC TOPMed gnomAD
CA389316901 rs1197718669	1764	G>V		No	ClinGen TOPMed gnomAD
CA7137590 rs776449975	1768	L>F		No	ClinGen ExAC gnomAD
CA7137591 rs747751902	1768	L>P		No	ClinGen ExAC gnomAD
rs376323843 CA7137592	1769	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA257938436 rs371368027	1769	T>P		No	ClinGen Ensembl
rs534007372 CA7137594 CA7137595	1770	E>D		No	ClinGen ExAC TOPMed gnomAD
CA389317016 rs1165414825	1771	P>L		No	ClinGen gnomAD
rs1405047712 CA389317037	1773	W>R		No	ClinGen gnomAD
rs1036951977 CA257938453	1774	W>R		No	ClinGen Ensembl
CA389317057 rs1594744297	1775	E>G		No	ClinGen Ensembl
rs759824815 CA389317054	1775	E>K		No	ClinGen ExAC TOPMed gnomAD
rs759824815 CA7137597	1775	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA389317069 rs1333883969	1776	M>I		No	ClinGen TOPMed
CA389317080 rs1362540271	1778	S>C		No	ClinGen gnomAD
CA7137598 rs767829132	1779	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1377742103 CA389317099	1781	I>L		No	ClinGen TOPMed
TCGA novel	1783	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200814392 CA7137599	1786	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA7137601 rs764202374	1788	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA7137603 rs758422413	1794	V>A		No	ClinGen ExAC gnomAD
rs536726550 CA389317201	1796	E>G		No	ClinGen Ensembl
CA257938474 rs536726550	1796	E>V		No	ClinGen Ensembl
CA389317215 rs201902763	1799	E>*		No	ClinGen 1000Genomes ExAC gnomAD
CA7137607 rs781109193	1799	E>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA7137606 rs201902763	1799	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs1002655975 CA257938480	1800	L>I		No	ClinGen TOPMed
rs1367098407 CA389317246	1803	R>M		No	ClinGen gnomAD
rs1594744341 CA389317253	1804	V>G		No	ClinGen Ensembl
rs747839895 CA7137608	1805	A>T		No	ClinGen ExAC TOPMed gnomAD
CA389317261 rs1339608892	1806	D>H		No	ClinGen TOPMed
CA7137609 rs769564116	1808	A>V		No	ClinGen ExAC TOPMed gnomAD
rs938993023 CA389317288	1809	S>R		No	ClinGen TOPMed
rs1297702227 CA389317292	1810	E>V		No	ClinGen gnomAD
TCGA novel	1812	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770409484 CA7137612	1812	A>V		No	ClinGen ExAC TOPMed gnomAD
CA7137613 rs774752532	1813	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1338493151 CA389317314	1813	E>V		No	ClinGen gnomAD
rs760041145 CA7137614	1814	N>H		No	ClinGen ExAC gnomAD
rs1566488892 CA389317323	1814	N>K		No	ClinGen Ensembl
TCGA novel	1815	R>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389317330 rs1355473794	1815	R>S		No	ClinGen gnomAD
rs772476072 CA7137616	1816	R>C		No	ClinGen ExAC TOPMed gnomAD
rs775804688 CA389317333	1816	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs775804688 CA7137617	1816	R>L		No	ClinGen ExAC gnomAD
CA389317342 rs1485678225	1817	F>L		No	ClinGen gnomAD
CA7137618 rs760956364	1818	K>E		No	ClinGen ExAC gnomAD
rs754037307 CA7137620	1819	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs201284188 CA7137619	1819	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137621 rs761826069	1821	S>G		No	ClinGen ExAC TOPMed
TCGA novel	1823	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389317410 rs1438137128	1827	N>D		No	ClinGen TOPMed gnomAD
rs1312293720 CA389317428	1829	G>D		No	ClinGen gnomAD
CA389317462 rs1361420119	1834	L>F		No	ClinGen gnomAD
rs1395784708 CA389317457	1834	L>M		No	ClinGen gnomAD
CA389317477 rs1174278471	1837	L>I		No	ClinGen gnomAD
CA389317479 rs1566488936	1837	L>P		No	ClinGen Ensembl
rs781199241 CA7137625	1838	P>H		No	ClinGen ExAC gnomAD
CA257938545 rs975820379	1839	R>S		No	ClinGen TOPMed gnomAD
CA257938548 rs1030125007	1842	S>N		No	ClinGen gnomAD
CA389317516 rs1566488962	1843	S>N		No	ClinGen Ensembl
CA389317578 rs1594744425	1847	V>G		No	ClinGen Ensembl
rs555050238 CA389317570	1847	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137626 rs555050238	1847	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7137627 rs755914335	1848	G>C		No	ClinGen ExAC gnomAD
rs777571893 CA7137628	1848	G>D		No	ClinGen ExAC gnomAD
TCGA novel	1848	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA7137629 rs748932229	1849	P>S		No	ClinGen ExAC gnomAD
CA7137630 rs770370515	1851	Y>H		No	ClinGen ExAC gnomAD
CA389317655 rs1199816879	1853	G>R		No	ClinGen TOPMed gnomAD
CA389317678 rs1594744444	1854	D>A		No	ClinGen Ensembl
CA7137634 COSM1218140 rs775892926	1855	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA389317691 rs1305524554	1855	R>W		No	ClinGen TOPMed gnomAD
rs1594744458 CA389317720	1857	S>G		No	ClinGen Ensembl
CA389317726 rs1371762480	1857	S>N		No	ClinGen TOPMed
CA389317733 rs1299993308	1857	S>R		No	ClinGen TOPMed
rs768946629 CA7137636	1859	S>L		No	ClinGen ExAC TOPMed gnomAD
rs1174108616 CA389317758	1860	L>F		No	ClinGen TOPMed gnomAD
rs1174108616 CA389317760	1860	L>I		No	ClinGen TOPMed gnomAD
rs1174108616 CA389317762	1860	L>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs776736984 CA7137637	1861	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA257938582 rs909436661	1861	Y>H		No	ClinGen Ensembl
rs1402198954 CA389317797	1862	R>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA257938590 rs373108431	1864	W>*		No	ClinGen ESP TOPMed
CA7137638 rs762068790	1865	G>S		No	ClinGen ExAC gnomAD
COSM1218139 rs1330287847 CA389317866	1867	P>S	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1388118011 CA389317905	1869	P>L		No	ClinGen gnomAD
CA389317932 rs1356502904	1871	K>Q		No	ClinGen Ensembl
rs1219797290 CA389317972	1873	G>E		No	ClinGen gnomAD
CA389317969 rs1219797290	1873	G>V		No	ClinGen gnomAD
CA389317978 rs750509257	1874	C>G		No	ClinGen ExAC TOPMed gnomAD
CA7137640 rs750509257	1874	C>R		No	ClinGen ExAC TOPMed gnomAD
rs1198353487 CA389317985	1874	C>S		No	ClinGen gnomAD
CA389317983 rs1198353487	1874	C>Y		No	ClinGen gnomAD
CA7137641 rs759603622	1876	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA257938604 rs867455391	1877	P>H		No	ClinGen Ensembl
CA389318034 rs1189695615	1878	S>N		No	ClinGen gnomAD
CA257938608 rs866697390	1881	M>I		No	ClinGen gnomAD
rs1194337988 CA389318094	1882	K>R		No	ClinGen gnomAD
rs767574535 CA257938614	1883	A>S		No	ClinGen ExAC gnomAD
CA7137642 rs767574535	1883	A>T		No	ClinGen ExAC gnomAD
CA257938618 rs996113992	1884	F>L		No	ClinGen TOPMed gnomAD
CA389318146 rs1169743905	1885	A>V		No	ClinGen gnomAD
TCGA novel	1886	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA257938621 rs1050413835	1886	K>R		No	ClinGen TOPMed
CA389318187 rs1350247589	1888	G>D		No	ClinGen gnomAD
rs752615470 CA7137643	1890	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1389392684 CA389318252	1893	F>L		No	ClinGen gnomAD
rs1164760591 CA389318309	1897	E>D		No	ClinGen TOPMed gnomAD
CA389318322 rs1218530793	1898	Q>H		No	ClinGen TOPMed gnomAD
CA389318311 rs1280678219	1898	Q>K		No	ClinGen gnomAD
rs772305906 CA257938631	1898	Q>R		No	ClinGen gnomAD

No associated diseases with Q9P2P1

5 regional properties for Q9P2P1

Type	Name	Position	InterPro Accession
domain	Integrase, catalytic core	1609 - 1730	IPR001584
domain	Ribonuclease H domain	1304 - 1450	IPR002156
domain	Ribonuclease Zc3h12a-like, NYN domain	792 - 942	IPR021869
domain	Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain	1130 - 1228	IPR041577
domain	Integrase zinc-binding domain	1536 - 1590	IPR041588

Functions

		Description
EC Number
Subcellular Localization	Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
cytoplasmic ribonucleoprotein granule	A ribonucleoprotein granule located in the cytoplasm.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name	Definition
endoribonuclease activity	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA-DNA hybrid ribonuclease activity	Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

3 GO annotations of biological process

Name	Definition
DNA integration	The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA repair	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
RNA phosphodiester bond hydrolysis, endonucleolytic	The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.

12 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
A4FUB7	GIN1	Gypsy retrotransposon integrase-like protein 1	Bos taurus (Bovine)	PR
Q6ZNG9	KRBA2	KRAB-A domain-containing protein 2	Homo sapiens (Human)	PR
Q6R2W3	ZBED9	SCAN domain-containing protein 3	Homo sapiens (Human)	PR
Q9UN19	DAPP1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	Homo sapiens (Human)	PR
O75113	N4BP1	NEDD4-binding protein 1	Homo sapiens (Human)	PR
Q9QXT1	Dapp1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	Mus musculus (Mouse)	PR
Q94KB1	MLO14	MLO-like protein 14	Arabidopsis thaliana (Mouse-ear cress)	PR
O80580	MLO15	MLO-like protein 15	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SMP1	XTH11	Probable xyloglucan endotransglucosylase/hydrolase protein 11	Arabidopsis thaliana (Mouse-ear cress)	PR
O49621	MLO1	MLO-like protein 1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FK75	At5g45670	GDSL esterase/lipase At5g45670	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FI00	MLO11	MLO-like protein 11	Arabidopsis thaliana (Mouse-ear cress)	PR

10	20	30	40	50	60
MLLSGGDPPA	QEWFMVQTKS	KPRVQRQRLQ	VQRIFRVKLN	AFQSRPDTPY	FWLQLEGPRE
70	80	90	100	110	120
NMGKAKEYLK	GLCSPELWKE	VRYPPILHCA	FLGAQGLFLD	CLCWSTLAYL	VPGPPGSLMV
130	140	150	160	170	180
GGLTESFIMT	QNWLEELVGR	LRWGPAPLLT	PRGIWEAEVT	RAFGALVWIR	GDQHAGDLLQ
190	200	210	220	230	240
LPPAVQELLL	SLVRDAAGKE	DIIEWLSRFG	ISDSHSDPEV	LICPPQQQKE	APAMVSVGES
250	260	270	280	290	300
PGPFVDMGTL	QNRGPENSKR	LSSLGATGSL	ITAQSTPQEA	ANQLVRVGSN	NQDGMDSAQE
310	320	330	340	350	360
EGTVQATSSQ	DSTNHTQALL	KQRQVQKIED	KLLFQPPVSA	LGVCPPWKAW	TPGPAFGPLW
370	380	390	400	410	420
PGAIAATFWR	INELHSLHLA	WLLSQACFNF	PFWQRPLGPI	QLKLPGQNPL	PLNLEWKQKE
430	440	450	460	470	480
LAPLPSAESP	AGRPDGGLGG	EAALQNCPRP	EISPKVTSLL	VVPGSSDVKD	KVSSDLPQIG
490	500	510	520	530	540
PPLTSTPQLQ	AGGEPGDQGS	MQLDFKGLEE	GPAPVLPTGQ	GKPVAQGGLT	DQSVPGAQTV
550	560	570	580	590	600
PETLKVPMAA	AVPKAENPSR	TQVPSAAPKL	PTSRMMLAVH	TEPAAPEVPL	APTKPTAQLM
610	620	630	640	650	660
ATAQKTVVNQ	PVLVAQVEPT	TPKTPQAQKM	PVAKTSPAGP	KTPKAQAGPA	ATVSKAPAAS
670	680	690	700	710	720
KAPAAPKVPV	TPRVSRAPKT	PAAQKVPTDA	GPTLDVARLL	SEVQPTSRAS	VSLLKGQGQA
730	740	750	760	770	780
GRQGPQSSGT	LALSSKHQFQ	MEGLLGAWEG	APRQPPRHLQ	ANSTVTSFQR	YHEALNTPFE
790	800	810	820	830	840
LNLSGEPGNQ	GLRRVVIDGS	SVAMVHGLQH	FFSCRGIAMA	VQFFWNRGHR	EVTVFVPTWQ
850	860	870	880	890	900
LKKNRRVRES	HFLTKLHSLK	MLSITPSQLE	NGKKITTYDY	RFMVKLAEET	DGIIVTNEQI
910	920	930	940	950	960
HILMNSSKKL	MVKDRLLPFT	FAGNLFMVPD	DPLGRDGPTL	DEFLKKPNRL	DTDIGNFLKV
970	980	990	1000	1010	1020
WKTLPPSSAS	VTELSDDADS	GPLESLPNME	EVREEKEERQ	DEEQRQGQGT	QKAAEEDDLD
1030	1040	1050	1060	1070	1080
SSLASVFRVE	CPSLSEEILR	CLSLHDPPDG	ALDIDLLPGA	ASPYLGIPWD	GKAPCQQVLA
1090	1100	1110	1120	1130	1140
HLAQLTIPSN	FTALSFFMGF	MDSHRDAIPD	YEALVGPLHS	LLKQKPDWQW	DQEHEEAFLA
1150	1160	1170	1180	1190	1200
LKRALVSALC	LMAPNSQLPF	RLEVTVSHVA	LTAILHQEHS	GRKHPIAYTS	KPLLPDEESQ
1210	1220	1230	1240	1250	1260
GPQSGGDSPY	AVAWALKHFS	RCIGDTPVVL	DLSYASRTTA	DPEVREGRRV	SKAWLIRWSL
1270	1280	1290	1300	1310	1320
LVQDKGKRAL	ELALLQGLLG	ENRLLTPAAS	MPRFFQVLPP	FSDLSTFVCI	HMSGYCFYRE
1330	1340	1350	1360	1370	1380
DEWCAGFGLY	VLSPTSPPVS	LSFSCSPYTP	TYAHLAAVAC	GLERFGQSPL	PVVFLTHCNW
1390	1400	1410	1420	1430	1440
IFSLLWELLP	LWRARGFLSS	DGAPLPHPSL	LSYIISLTSG	LSSLPFIYRT	SYRGSLFAVT
1450	1460	1470	1480	1490	1500
VDTLAKQGAQ	GGGQWWSLPK	DVPAPTVSPH	AMGKRPNLLA	LQLSDSTLAD	IIARLQAGQK
1510	1520	1530	1540	1550	1560
LSGSSPFSSA	FNSLSLDKES	GLLMFKGDKK	PRVWVVPTQL	RRDLIFSVHD	IPLGAHQRPE
1570	1580	1590	1600	1610	1620
ETYKKLRLLG	WWPGMQEHVK	DYCRSCLFCI	PRNLIGSELK	VIESPWPLRS	TAPWSNLQIE
1630	1640	1650	1660	1670	1680
VVGPVTISEE	GHKHVLIVAD	PNTRWVEAFP	LKPYTHTAVA	QVLLQHVFAR	WGVPVRLEAA
1690	1700	1710	1720	1730	1740
QGPQFARHVL	VSCGLALGAQ	VASLSRDLQF	PCLTSSGAYW	EFKRALKEFI	FLHGKKWAAS
1750	1760	1770	1780	1790	1800
LPLLHLAFRA	SSTDATPFKV	LTGGESRLTE	PLWWEMSSAN	IEGLKMDVFL	LQLVGELLEL
1810	1820	1830	1840	1850	1860
HWRVADKASE	KAENRRFKRE	SQEKEWNVGD	QVLLLSLPRN	GSSAKWVGPF	YIGDRLSLSL
1870	1880	1890
YRIWGFPTPE	KLGCIYPSSL	MKAFAKSGTP	LSFKVLEQ