AiPD: Autoinhibited Protein Database

Q9P241

Gene name	ATP10D
Protein name	Phospholipid-transporting ATPase VD
Names	ATPase class V type 10D, P4-ATPase flippase complex alpha subunit ATP10D
Species	Homo sapiens (Human)
KEGG Pathway	hsa:57205
EC number	7.6.2.1: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1326-1404 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1326-1404 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9P241

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9P241-F1	Predicted				AlphaFoldDB

1161 variants for Q9P241

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA2908015 rs745570202	4	A>T		No	ClinGen ExAC gnomAD
rs1577629046 CA356775858	5	L>F		No	ClinGen Ensembl
CA2908016 rs199628718	6	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA96641883 rs199628718	6	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs1212400672 CA356775870	7	W>*		No	ClinGen gnomAD
rs763546918 CA2908018	7	W>R		No	ClinGen ExAC TOPMed gnomAD
CA356775907 rs1577629114	12	W>R		No	ClinGen Ensembl
CA2908020 rs774800431	13	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs111932778 CA2908021	13	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA2908023 rs750580060	14	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs767742740 CA2908022	14	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1184942423 CA356775932	17	R>G		No	ClinGen gnomAD
rs1299699640 CA356775934	17	R>K		No	ClinGen TOPMed
rs766357970 CA2908025	18	G>R		No	ClinGen ExAC gnomAD
rs1462262033 CA356775951	20	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA2908026 rs754017045	20	T>I		No	ClinGen ExAC gnomAD
CA356775954 rs754017045	20	T>S		No	ClinGen ExAC gnomAD
rs1344930454 CA356775995	26	G>E		No	ClinGen gnomAD
CA2908029 rs375980643	27	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908030 rs375980643	27	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA356776008 rs1379513033	28	Y>*		No	ClinGen gnomAD
CA2908031 rs751316006	28	Y>C		No	ClinGen ExAC gnomAD
CA2908032 rs757014021	29	N>S		No	ClinGen ExAC gnomAD
CA2908035 rs138139630	30	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908034 rs745489831	30	Y>D		No	ClinGen ExAC gnomAD
CA96641978 rs745489831	30	Y>H		No	ClinGen ExAC gnomAD
CA96641982 rs138139630	30	Y>S		No	ClinGen ESP ExAC TOPMed gnomAD
COSM1694334 CA96641985 rs772782452	31	S>F	skin [Cosmic]	No	ClinGen cosmic curated Ensembl
rs199950421 CA2908037	32	S>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356776027 rs1163668388	32	S>T		No	ClinGen gnomAD
rs199950421 CA96642006	32	S>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA96642021 rs373598354	33	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs143618340 CA356776042	35	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs143618340 CA2908041	35	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908042 rs773685085	38	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs760805456 CA356776063 COSM243107	38	R>H	lung Variant assessed as Somatic; 0.0 impact. prostate [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs760805456 CA2908043	38	R>L		No	ClinGen ExAC TOPMed gnomAD
rs1399321730 CA356776075	40	S>Y		No	ClinGen gnomAD
VAR_048385 CA2908045 rs33995001	43	T>I		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA2908048 rs765340052	44	P>A		No	ClinGen ExAC gnomAD
CA2908047 rs765340052	44	P>S		No	ClinGen ExAC gnomAD
TCGA novel	44	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356776123 rs1278870211	48	G>E		No	ClinGen TOPMed gnomAD
rs750234424 CA2908051	51	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA2908050 rs202028690	51	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs916763878 CA96642060	52	I>L		No	ClinGen gnomAD
CA2908052 rs755667737	55	P>S		No	ClinGen ExAC gnomAD
CA356776170 rs1577629541	56	H>P		No	ClinGen Ensembl
rs1254583453 CA356776169	56	H>Y		No	ClinGen TOPMed
CA96642110 rs374344538	59	P>S		No	ClinGen ESP TOPMed
rs778615439 CA2908056	61	K>N		No	ClinGen ExAC gnomAD
CA2908058 rs772704541	62	D>G		No	ClinGen ExAC gnomAD
CA96642118 rs533561156	62	D>N		No	ClinGen ExAC gnomAD
CA2908057 rs533561156	62	D>Y		No	ClinGen ExAC gnomAD
CA96642120 rs370135326	63	E>K		No	ClinGen ESP TOPMed
rs1261383806 CA356776226	64	Y>C		No	ClinGen TOPMed
CA2908059 rs773384255	65	E>D		No	ClinGen ExAC gnomAD
COSM339826 rs1193451427 CA356776230	65	E>K	lung [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1171298737 CA356776257	68	S>C		No	ClinGen TOPMed gnomAD
TCGA novel	69	G>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776801919 CA2908062 COSM189856	69	G>R	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1327649319 CA356776265	70	A>P		No	ClinGen TOPMed gnomAD
rs1327649319 CA356776264	70	A>T		No	ClinGen TOPMed gnomAD
rs759803259 CA2908063	70	A>V		No	ClinGen ExAC gnomAD
CA96642185 rs898368908	71	Y>C		No	ClinGen TOPMed gnomAD
CA2908065 rs775610558	72	V>M		No	ClinGen ExAC
CA356776285 rs1297133400	73	N>S		No	ClinGen TOPMed
CA356776289 rs1233057725	74	N>H		No	ClinGen Ensembl
CA2908066 rs118048800	74	N>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908067 COSM1245681 rs373001297	75	R>*	oesophagus [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA551149421 rs1560417089	75	R>*		No	ClinGen Ensembl
COSM256370 CA2908068 rs750138858	75	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA356776304 rs1196433876	76	I>M		No	ClinGen gnomAD
rs760552115 CA2908069	76	I>V		No	ClinGen ExAC TOPMed gnomAD
rs766319846 CA2908070	77	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA96642245 rs149671949	77	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA gnomAD
CA2908072 rs754735402	78	T>A		No	ClinGen ExAC gnomAD
rs1475707410 CA356776314	79	T>A		No	ClinGen TOPMed
COSM1670997 rs908093392 CA96642258	81	Y>S	breast [Cosmic]	No	ClinGen cosmic curated Ensembl
CA356776342 rs1187791331	83	L>F		No	ClinGen TOPMed gnomAD
CA2908074 rs752261830	83	L>R		No	ClinGen ExAC gnomAD
CA2908076 rs778373594	84	L>P		No	ClinGen ExAC gnomAD
CA2908077 rs747510569	85	N>D		No	ClinGen ExAC gnomAD
CA356776364 rs1326424708	87	V>M		No	ClinGen gnomAD
CA2908079 rs534550458	92	F>Y		No	ClinGen 1000Genomes ExAC gnomAD
CA356776427 rs1438407498	95	F>L		No	ClinGen TOPMed gnomAD
CA2908080 rs746082899	96	H>D		No	ClinGen ExAC TOPMed gnomAD
CA2908081 rs746082899	96	H>Y		No	ClinGen ExAC TOPMed gnomAD
rs967659275 CA356776435	97	R>G		No	ClinGen TOPMed gnomAD
rs184019410 CA2908107	101	L>S		No	ClinGen 1000Genomes ExAC gnomAD
CA356776600 rs1161214162	102	Y>*		No	ClinGen gnomAD
rs893455576 CA96644130	103	F>I		No	ClinGen TOPMed
TCGA novel	103	F>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356776613 rs1452782300	105	F>L		No	ClinGen gnomAD
TCGA novel	106	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908110 rs763651667	107	V>A		No	ClinGen ExAC gnomAD
CA2908111 rs371064535	108	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs757700600 CA2908112	110	N>S		No	ClinGen ExAC TOPMed gnomAD
CA356776654 rs1413024428	111	W>*		No	ClinGen gnomAD
TCGA novel	112	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768032388 CA2908113	114	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1433029470 CA356776670	114	L>V		No	ClinGen gnomAD
CA2908115 rs750749360	117	A>T		No	ClinGen ExAC gnomAD
COSM1540335 CA356776694 rs1449420927	118	F>L	lung [Cosmic]	No	ClinGen cosmic curated TOPMed
CA356776703 rs1238757013	119	Q>E		No	ClinGen gnomAD
TCGA novel	121	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1472346066 CA356776736	123	T>I		No	ClinGen Ensembl
rs1259285953 CA356776741	124	M>V		No	ClinGen gnomAD
rs1350547704 CA356776754	125	L>F		No	ClinGen TOPMed gnomAD
CA356776757 rs1211078299	126	P>A		No	ClinGen gnomAD
CA356776767 rs1484397911	128	V>L		No	ClinGen gnomAD
CA356776768 rs1484397911	128	V>M		No	ClinGen gnomAD
CA356776772 rs1178498512	129	V>M		No	ClinGen TOPMed gnomAD
rs566390429 CA2908118	132	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356776797 rs1179603674	133	I>V		No	ClinGen gnomAD
CA356776813 rs1174429574	135	A>G		No	ClinGen gnomAD
CA2908120 rs755222321	135	A>T		No	ClinGen ExAC TOPMed gnomAD
CA356776821 rs1212960459	137	K>Q		No	ClinGen gnomAD
CA356776825 rs1290706431	137	K>T		No	ClinGen TOPMed
CA356776833 rs1375127841 COSM1642479	138	D>G	stomach [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1179841672 CA356776837	139	G>S		No	ClinGen Ensembl
rs778984994 CA2908121	143	Y>F		No	ClinGen ExAC gnomAD
rs770945581 CA2908123	144	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA2908122 rs748191553	144	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1373575522 CA356776883	146	Y>H		No	ClinGen gnomAD
rs745848496 CA2908126	151	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA2908127 rs1348991982	152	I>N		No	ClinGen TOPMed gnomAD
CA356776931 rs1348991982	152	I>T		No	ClinGen TOPMed gnomAD
CA356776929 rs1345346672	152	I>V		No	ClinGen gnomAD
CA96644229 rs926064307	156	I>V		No	ClinGen Ensembl
TCGA novel	157	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908131 rs775214799	158	K>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA356776988 rs1560419071	160	Y>*		No	ClinGen Ensembl
rs889046802 CA96644237	160	Y>C		No	ClinGen TOPMed gnomAD
rs1428472104 CA356776994	161	S>N		No	ClinGen TOPMed
rs558389505 CA2908160	163	K>R		No	ClinGen 1000Genomes ExAC TOPMed
TCGA novel	164	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773846255 CA2908161	164	E>K		No	ClinGen ExAC gnomAD
CA356777441 rs1427076629	164	E>V		No	ClinGen TOPMed
TCGA novel	166	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1420625292 CA356777464	166	K>T		No	ClinGen gnomAD
rs1164871207 CA356777492	168	I>T		No	ClinGen gnomAD
rs1421944037 CA356777504	169	D>G		No	ClinGen TOPMed
CA2908164 rs771557660	170	R>*		No	ClinGen ExAC TOPMed gnomAD
CA2908165 rs74568336	170	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs7683838 VAR_048386 CA2908166	171	C>R		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA356777517 rs7683838	171	C>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs766813065 CA2908167	171	C>Y		No	ClinGen ExAC gnomAD
rs765680826 CA2908170	175	V>I		No	ClinGen ExAC TOPMed gnomAD
CA356777567 rs1305498021	176	T>A		No	ClinGen TOPMed
rs758757182 CA2908172	177	V>A		No	ClinGen ExAC gnomAD
rs1371965807 CA356777588	179	D>V		No	ClinGen gnomAD
CA2908174 rs200556408	182	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
RCV000975037 CA2908175 rs114311534	182	R>H		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA96648951 rs182993483	184	S>P		No	ClinGen 1000Genomes
TCGA novel	185	C>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908176 rs779885363	185	C>R		No	ClinGen ExAC TOPMed gnomAD
rs749286393 CA356777634	186	N>K		No	ClinGen ExAC TOPMed gnomAD
rs376532237 CA2908179	187	E>D		No	ClinGen ESP ExAC gnomAD
rs371624169 CA2908178	187	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA356777640 rs1577642767	187	E>V		No	ClinGen Ensembl
CA96648999 rs888485233	188	V>L		No	ClinGen TOPMed gnomAD
rs1412336116 CA356777650	189	I>N		No	ClinGen gnomAD
CA356777658 rs1402799834	190	P>L		No	ClinGen gnomAD
rs1282955975 CA356777656	190	P>S		No	ClinGen TOPMed gnomAD
TCGA novel	191	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96649017 rs761176128	193	M>I		No	ClinGen gnomAD
CA96649012 rs776216011	193	M>T		No	ClinGen Ensembl
rs1034594160 CA96649002	193	M>V		No	ClinGen Ensembl
rs1314340108 CA356777694	194	V>I		No	ClinGen TOPMed gnomAD
rs1314340108 CA356777697	194	V>L		No	ClinGen TOPMed gnomAD
CA96649048 rs951143810	196	L>F		No	ClinGen TOPMed gnomAD
rs1461890943 CA356777717	196	L>H		No	ClinGen Ensembl
CA2908184 rs771431785	197	F>S		No	ClinGen ExAC gnomAD
rs776974710 CA2908185	202	D>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	205	C>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764970382 CA96649056	207	I>T		No	ClinGen TOPMed
rs760145099 CA2908186	208	E>G		No	ClinGen ExAC gnomAD
TCGA novel	212	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96649072 rs200306183	212	L>P		No	ClinGen 1000Genomes
CA2908188 rs753112385	213	D>N		No	ClinGen ExAC gnomAD
rs1486032355 CA356777919	215	E>K		No	ClinGen gnomAD
CA356777937 rs1236195378	216	S>C		No	ClinGen gnomAD
CA2908190 rs764432218	220	Q>H		No	ClinGen ExAC gnomAD
COSM309339 rs1205596215 CA356777991	221	R>G	lung [Cosmic]	No	ClinGen cosmic curated TOPMed
TCGA novel	221	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1577642986 CA356778034	223	V>G		No	ClinGen Ensembl
CA356778050 rs559976209	225	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs559976209 CA2908192	225	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs192815760 COSM1055707 CA96649097	225	R>W	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes NCI-TCGA TOPMed gnomAD
CA96649107 rs912415432	226	G>E		No	ClinGen gnomAD
CA356778084 rs1390109385	228	A>V		No	ClinGen TOPMed
rs1309088477 CA356778099	230	Q>E		No	ClinGen TOPMed
CA356778140 rs1195896394	234	V>F		No	ClinGen TOPMed
CA2908216 rs754814555	235	D>N		No	ClinGen ExAC TOPMed gnomAD
CA2908217 rs765186564	237	E>D		No	ClinGen ExAC gnomAD
CA356778168 rs1232753927	238	K>E		No	ClinGen gnomAD
rs140687448 CA2908218	238	K>T		No	ClinGen ESP ExAC gnomAD
CA96650896 rs998690829	241	S>G		No	ClinGen gnomAD
rs1341549219 CA356778211	244	E>A		No	ClinGen gnomAD
rs889975234 CA96650916	247	S>R		No	ClinGen gnomAD
TCGA novel	248	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908220 rs144361524	249	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA356778259 rs1456863048	250	N>K		No	ClinGen gnomAD
CA2908221 rs746635713	251	D>A		No	ClinGen ExAC gnomAD
rs756936486 CA2908222	253	S>N		No	ClinGen ExAC TOPMed gnomAD
CA2908223 rs780506636	253	S>R		No	ClinGen ExAC gnomAD
COSM1055708 CA356778295 rs1243544755	256	R>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs201697796 COSM4005773 CA2908224	256	R>Q	urinary_tract [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
TCGA novel	261	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773456330 CA96656562	263	N>I		No	ClinGen ExAC TOPMed gnomAD
rs1438148196 CA356778475	263	N>K		No	ClinGen TOPMed gnomAD
CA2908250 rs773456330	263	N>S		No	ClinGen ExAC TOPMed gnomAD
rs200864587 CA2908251	264	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908253 rs776693676	265	E>K		No	ClinGen ExAC gnomAD
CA2908254 rs762815957	266	R>C		No	ClinGen ExAC TOPMed gnomAD
rs146578598 CA2908255 COSM1660676	266	R>H	kidney [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs146578598 CA96656587	266	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
COSM1540333 CA356778494 rs185611178 CA2908257	267	V>L	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA2908258 rs185611178	267	V>M	Variant assessed as Somatic; 0.001435 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA2908259 rs750075191	268	G>C		No	ClinGen ExAC gnomAD
rs750075191 CA2908260	268	G>S		No	ClinGen ExAC gnomAD
rs561198097 CA2908261	269	L>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908262 rs753412403	271	K>E		No	ClinGen ExAC gnomAD
TCGA novel	272	E>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96656617 rs528576045	272	E>Q		No	ClinGen 1000Genomes TOPMed
rs370605939 CA96656624	279	C>S		No	ClinGen ESP TOPMed gnomAD
rs201934143 CA2908264	281	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356778589 rs1461129473	282	R>*		No	ClinGen TOPMed gnomAD
CA356778600 rs1560430191	283	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs760633635 CA2908265	284	T>K		No	ClinGen ExAC gnomAD
rs760633635 CA2908266	284	T>R		No	ClinGen ExAC gnomAD
rs374631722 CA96656627	284	T>S		No	ClinGen ESP
CA2908267 rs76089900	287	V>G		No	ClinGen 1000Genomes ExAC gnomAD
CA356778621 rs1336662697	287	V>I		No	ClinGen gnomAD
rs890727519 CA96656639	289	G>V		No	ClinGen TOPMed gnomAD
CA356778638 rs747164353	290	I>F		No	ClinGen ExAC TOPMed gnomAD
CA2908268 rs747164353	290	I>L		No	ClinGen ExAC TOPMed gnomAD
CA356778637 rs747164353	290	I>V		No	ClinGen ExAC TOPMed gnomAD
CA2908269 rs200685217	291	V>A		No	ClinGen 1000Genomes ExAC gnomAD
rs776638541 CA2908270	292	V>A		No	ClinGen ExAC TOPMed gnomAD
rs776638541 CA356778652	292	V>G		No	ClinGen ExAC TOPMed gnomAD
CA356778648 rs1254868676	292	V>I		No	ClinGen gnomAD
rs1398177093 CA356778665	294	A>V		No	ClinGen Ensembl
rs757426388 CA2908288	295	G>A		No	ClinGen ExAC gnomAD
CA2908289 rs201618087	296	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs1397067052 CA356778704	298	T>I		No	ClinGen gnomAD
COSM1429866 rs775497302 CA2908292	304	N>S	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs372137686 CA2908294	305	S>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA96656712 rs372137686	305	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1295613825 CA356778754	306	G>R		No	ClinGen gnomAD
rs766321491 CA2908297	308	R>Q		No	ClinGen ExAC gnomAD
CA2908295 rs773093019	308	R>W		No	ClinGen ExAC TOPMed gnomAD
rs900203773 CA96656720	309	Y>*		No	ClinGen Ensembl
CA2908298 rs138739908	311	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs759172595 COSM268724 CA2908299	311	R>H	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1319260001 CA356778789	312	S>G		No	ClinGen TOPMed
rs764802901 CA2908300	316	R>K		No	ClinGen ExAC gnomAD
TCGA novel	318	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1188541967 CA356778841	319	N>D		No	ClinGen gnomAD
CA2908302 VAR_048387 rs35596623	320	T>I		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA2908303 rs35596623	320	T>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs757594467 CA2908305	324	W>*		No	ClinGen ExAC TOPMed gnomAD
rs757594467 CA356778877	324	W>C		No	ClinGen ExAC TOPMed gnomAD
rs1375049585 CA356778884	325	C>F		No	ClinGen gnomAD
rs781594438 CA2908306	325	C>W		No	ClinGen ExAC gnomAD
TCGA novel	326	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746096825 CA2908307	326	V>F		No	ClinGen ExAC gnomAD
CA96656747 rs1009918347	327	M>I		No	ClinGen gnomAD
CA356778909 rs1275668699	329	L>P		No	ClinGen TOPMed
CA2908308 rs756292540	330	V>D		No	ClinGen ExAC gnomAD
CA356778920 rs1359279094	331	I>T		No	ClinGen gnomAD
CA356778931 rs1295045253	332	M>I		No	ClinGen gnomAD
rs1333506681 CA356778927	332	M>T		No	ClinGen TOPMed
rs35012290 CA2908313	337	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_048388 rs35012290 CA2908312	337	A>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs766733094 CA96656763	339	G>C		No	ClinGen ExAC TOPMed gnomAD
rs766733094 CA2908314	339	G>R		No	ClinGen ExAC TOPMed gnomAD
CA356778987 rs1223958103	340	H>N		No	ClinGen TOPMed
CA2908330 rs755089954	343	W>*		No	ClinGen ExAC TOPMed gnomAD
rs755089954 CA2908329	343	W>L		No	ClinGen ExAC TOPMed gnomAD
rs770999094 CA2908332	344	L>Q		No	ClinGen ExAC gnomAD
CA2908331 rs139274170	344	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs769666688 CA2908335	349	K>N		No	ClinGen ExAC gnomAD
rs745700006 CA2908334	349	K>R		No	ClinGen ExAC TOPMed gnomAD
CA356779057 rs1379278368	350	M>K		No	ClinGen gnomAD
CA356779054 rs1279903519	350	M>V		No	ClinGen TOPMed
rs372209013 CA2908336	352	F>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	353	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1173867819 CA356779086	354	N>D		No	ClinGen gnomAD
rs911237323	354	N>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA2908339 rs375885788	354	N>S		No	ClinGen ESP ExAC gnomAD
CA2908338 rs375885788	354	N>T		No	ClinGen ESP ExAC gnomAD
CA2908340 rs368872869	355	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1458995636 CA356779097	356	P>S		No	ClinGen TOPMed
rs1027687734 CA96656966	357	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA356779103 rs1027687734	357	E>Q		No	ClinGen TOPMed gnomAD
CA356779114 rs1170617893	358	P>L		No	ClinGen TOPMed
rs574679729 CA2908342	359	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1432966142 CA356779129	361	H>D		No	ClinGen TOPMed
rs766816894 CA2908344	361	H>R		No	ClinGen ExAC TOPMed gnomAD
CA96656977 rs866399116	362	I>L		No	ClinGen Ensembl
CA356779153 rs1277082849	364	S>L		No	ClinGen gnomAD
CA96656985 rs966118368	366	L>Q		No	ClinGen Ensembl
CA2908346 rs755322897	367	L>F		No	ClinGen ExAC TOPMed gnomAD
CA2908347 rs550923470	369	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA2908348 rs550923470	369	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1195098453 CA356779189	371	Y>H		No	ClinGen gnomAD
rs1170351123 CA356779203	372	M>I		No	ClinGen gnomAD
CA356779199 rs373358503	372	M>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs373358503 CA2908349	372	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1246997944 CA356779197	372	M>V		No	ClinGen gnomAD
rs780956265 CA2908350	373	F>L		No	ClinGen ExAC gnomAD
CA356779221 rs1466037390	375	T>A		No	ClinGen gnomAD
rs1169874854 CA356779224	375	T>S		No	ClinGen gnomAD
TCGA novel	376	M>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745864353 CA2908351	376	M>V		No	ClinGen ExAC gnomAD
CA356779236 rs1462868585	377	I>V		No	ClinGen gnomAD
CA96657004 rs964240618	378	I>F		No	ClinGen TOPMed gnomAD
CA356779242 rs964240618	378	I>V		No	ClinGen TOPMed gnomAD
rs1331940936 CA356779252	379	L>F		No	ClinGen TOPMed gnomAD
TCGA novel	382	V>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM84855 CA356779302 rs1215309523	385	P>S	Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA2908368 rs758527471	386	I>S		No	ClinGen ExAC gnomAD
CA2908367 rs753004084	386	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1381325935 CA356779317	387	S>F		No	ClinGen TOPMed gnomAD
rs779845954 CA96657073	388	L>V		No	ClinGen TOPMed gnomAD
rs138737356 CA2908373	389	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908371 rs764289473	389	Y>H		No	ClinGen ExAC gnomAD
rs138737356 CA2908372	389	Y>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356779341 rs1297607731	392	I>V		No	ClinGen gnomAD
COSM1429868 CA2908376 rs754586853	393	E>K	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1310439721 CA356779350	393	E>V		No	ClinGen gnomAD
CA356779367 rs1335464122	396	K>Q		No	ClinGen gnomAD
rs778507335 CA2908377	398	G>V		No	ClinGen ExAC gnomAD
CA2908378 rs747849029	400	I>M		No	ClinGen ExAC TOPMed gnomAD
rs1378404086 CA356779399	400	I>T		No	ClinGen TOPMed
rs1354032805 CA356779404	401	Y>C		No	ClinGen TOPMed gnomAD
rs771471852 CA2908379	401	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA2908380 rs772847899	403	I>V		No	ClinGen ExAC TOPMed gnomAD
rs747410568 CA2908381	404	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA356779447 rs1255469089	407	V>M		No	ClinGen gnomAD
CA356779452 rs1486211873	408	D>H		No	ClinGen gnomAD
rs1056790780 CA96657099	408	D>V		No	ClinGen TOPMed gnomAD
CA96657106 rs995865598	411	N>D		No	ClinGen Ensembl
rs371554019 CA2908382	411	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	412	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908383 rs200956632	412	E>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs759945258 CA2908384	413	K>E		No	ClinGen ExAC TOPMed gnomAD
CA2908385 rs765741714	413	K>R		No	ClinGen ExAC gnomAD
CA96657116 rs147390403	414	M>I		No	ClinGen 1000Genomes
TCGA novel	414	M>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356779501 rs1173662457	415	D>N		No	ClinGen gnomAD
rs1402165168 CA356779512	416	S>Y		No	ClinGen TOPMed gnomAD
rs1333730208 CA356779519	417	I>T		No	ClinGen gnomAD
CA2908386 rs775839118	417	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA2908387 rs200358319	419	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs764011636 CA2908388	420	C>G		No	ClinGen ExAC gnomAD
rs751670908 CA2908390	421	R>*		No	ClinGen ExAC TOPMed gnomAD
CA2908391 rs376991791	421	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs776065711 CA96657137	425	I>T		No	ClinGen TOPMed
rs778738719 CA2908395	427	E>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	429	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908396 rs747797887	430	G>E		No	ClinGen ExAC gnomAD
rs1238492373 CA356779603	431	Q>P		No	ClinGen gnomAD
rs1236647760 CA356779633	435	L>H		No	ClinGen gnomAD
TCGA novel	435	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908397 rs150738679	435	L>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA gnomAD
CA356779640 rs1317934441	436	F>S		No	ClinGen gnomAD
rs777093283 CA2908398	437	S>F		No	ClinGen ExAC gnomAD
CA2908400 rs770384605	438	D>N		No	ClinGen ExAC gnomAD
CA2908402 rs746432231	439	K>E		No	ClinGen ExAC gnomAD
rs1401467288 CA356779659	439	K>R		No	ClinGen gnomAD
rs1465497193 CA356779668	440	T>I		No	ClinGen gnomAD
rs1369347220 CA356779679	442	T>N		No	ClinGen gnomAD
CA2908405 rs370204271	443	L>F		No	ClinGen ESP ExAC gnomAD
CA2908406 rs768945023	449	V>I		No	ClinGen ExAC gnomAD
CA2908407 rs375420700	451	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908408 rs375420700	451	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs149876632 CA2908409	451	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	451	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1196566227 CA356779756	454	S>G		No	ClinGen gnomAD
TCGA novel	456	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908412 rs764948670	457	G>E		No	ClinGen ExAC gnomAD
CA2908414 rs146396794	459	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA96657191 rs974834968	461	C>F		No	ClinGen gnomAD
CA356779815 rs1479504628	462	H>P		No	ClinGen gnomAD
CA356779817 rs1196465984	462	H>Q		No	ClinGen TOPMed gnomAD
CA356779813 rs1479504628	462	H>R		No	ClinGen gnomAD
CA356779826 rs1262155234	464	E>K		No	ClinGen TOPMed
rs1029604668 CA96657194	466	A>S		No	ClinGen Ensembl
CA356806207 rs1264025199	467	R>G		No	ClinGen gnomAD
rs915869872 CA96630890	467	R>K		No	ClinGen TOPMed
rs139734817 CA2908428	467	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1185295382 CA356806216	468	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs551719524 CA2908429	472	Y>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs765184948 CA356806250	473	Q>P		No	ClinGen ExAC gnomAD
CA2908430 rs765184948	473	Q>R		No	ClinGen ExAC gnomAD
rs752397590 CA2908431	476	V>I		No	ClinGen ExAC gnomAD
rs371369194 CA356806290	479	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1298216696 CA356806288	479	D>H		No	ClinGen gnomAD
rs371369194 CA2908432	479	D>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908437 rs570265180	485	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs570265180 CA2908438	485	T>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908436 rs756861927	485	T>P		No	ClinGen ExAC gnomAD
TCGA novel	487	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs756648919 CA2908439	488	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1455829097 CA356806369	491	S>G		No	ClinGen TOPMed
rs749809273 CA2908441	491	S>N		No	ClinGen ExAC TOPMed gnomAD
CA2908442 rs769051611	492	N>S		No	ClinGen ExAC gnomAD
CA2908443 rs201342683	496	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA356806409 rs201342683	496	P>R		No	ClinGen ExAC TOPMed gnomAD
CA356806407 rs1178198907	496	P>S		No	ClinGen TOPMed
CA2908445 rs772297522	497	R>G		No	ClinGen ExAC gnomAD
CA356806412 rs1379092582	497	R>T		No	ClinGen gnomAD
CA96630971 rs946132651	498	A>S		No	ClinGen TOPMed gnomAD
COSM189866 CA356806416 rs946132651	498	A>T	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA356806426 rs1359722592	499	P>L		No	ClinGen gnomAD
CA356806425 rs1359722592	499	P>R		No	ClinGen gnomAD
CA356806428 COSM1055715 rs1300826153	500	S>G	Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1300826153 CA356806427	500	S>R		No	ClinGen TOPMed gnomAD
rs771042542 CA2908448	501	C>Y		No	ClinGen ExAC gnomAD
CA356806442 rs1449205291	502	R>G		No	ClinGen gnomAD
rs368473880 CA2908449	502	R>K		No	ClinGen ESP ExAC gnomAD
rs1376252114 CA356806449	503	T>A		No	ClinGen gnomAD
rs1222175179 CA356806451	503	T>K		No	ClinGen gnomAD
CA356806456 rs1336984892	504	V>F		No	ClinGen TOPMed gnomAD
rs1336984892 CA356806455	504	V>L		No	ClinGen TOPMed gnomAD
rs762862117 CA2908450	505	H>L		No	ClinGen ExAC gnomAD
rs935415055 CA96631001 COSM1694338	505	H>Y	Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA356806466 rs375658947	506	N>H		No	ClinGen ESP TOPMed gnomAD
TCGA novel	506	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1238886179 CA356806469	506	N>S		No	ClinGen TOPMed
rs375658947 CA96631013	506	N>Y		No	ClinGen ESP TOPMed gnomAD
CA2908452 rs763879616	507	G>E		No	ClinGen ExAC gnomAD
rs763879616 CA2908451	507	G>V		No	ClinGen ExAC gnomAD
CA2908454 rs767308709	508	P>S		No	ClinGen ExAC gnomAD
CA356806486 rs1237258989	509	L>W		No	ClinGen gnomAD
VAR_048389 rs10003238 CA2908455	511	N>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA356806505 rs1192378861	512	K>T		No	ClinGen gnomAD
CA2908457 rs766044821	513	P>H		No	ClinGen ExAC TOPMed gnomAD
rs755662432 CA2908456	513	P>T		No	ClinGen ExAC gnomAD
rs1402184760 CA356806522	515	N>Y		No	ClinGen gnomAD
rs754366272 CA2908458	516	H>R		No	ClinGen ExAC gnomAD
CA356806539 rs1332265720	517	L>P		No	ClinGen gnomAD
rs1335445003 CA356806541	518	A>T		No	ClinGen TOPMed gnomAD
rs779280395 CA2908460	519	G>A		No	ClinGen ExAC TOPMed gnomAD
rs1368400035 CA356806558	520	S>R		No	ClinGen gnomAD
VAR_048390 CA2908461 rs6843325	522	F>L		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA356806577 rs1281995538	523	T>N		No	ClinGen gnomAD
rs979088273 CA96631052	524	L>V		No	ClinGen gnomAD
CA356806596 rs1199716855	526	S>R		No	ClinGen gnomAD
rs1158341472 CA356806597	527	G>R		No	ClinGen TOPMed
rs200261195 CA2908462	529	G>R		No	ClinGen ExAC TOPMed gnomAD
rs777944967 CA2908463	531	S>T		No	ClinGen ExAC gnomAD
rs750911845 CA96631072	533	V>M		No	ClinGen Ensembl
rs1031184882 CA96631073	534	P>L		No	ClinGen TOPMed
CA356806651 rs1477444082	535	H>L		No	ClinGen gnomAD
CA356806679 rs1197190099	539	A>V		No	ClinGen gnomAD
CA2908465 rs770991094	540	A>S		No	ClinGen ExAC gnomAD
rs1050646175 CA96631079	541	F>L		No	ClinGen TOPMed
CA356806696 rs1478011275	542	S>G		No	ClinGen gnomAD
rs1472485037 CA356806697	542	S>N		No	ClinGen TOPMed
CA2908466 rs776575392	543	S>N		No	ClinGen ExAC gnomAD
rs1256745206 CA356806711	544	P>S		No	ClinGen TOPMed
rs201603122 CA2908467	545	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908489 rs773146199	547	T>A		No	ClinGen ExAC gnomAD
rs1329834300 CA356806986	547	T>R		No	ClinGen Ensembl
CA2908491 rs187144508	549	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908493 rs545511405	553	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	555	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs557426590 CA2908494	557	D>A		No	ClinGen 1000Genomes ExAC gnomAD
rs557426590 CA2908495	557	D>G		No	ClinGen 1000Genomes ExAC gnomAD
rs1161921828 CA356807057	558	K>I		No	ClinGen gnomAD
rs1420461014 CA356807070	560	S>G		No	ClinGen TOPMed gnomAD
rs1158468055 CA356807071	560	S>T		No	ClinGen gnomAD
rs764382228 CA2908497	562	I>S		No	ClinGen ExAC gnomAD
rs751940328 CA356807094	563	T>I		No	ClinGen ExAC gnomAD
rs751940328 CA2908498	563	T>R		No	ClinGen ExAC gnomAD
rs781238830 CA2908501 COSM587404	565	R>L	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs781238830 CA2908500	565	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA2908499 rs757458517	565	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA356807106 rs1258869423	566	L>H		No	ClinGen gnomAD
CA356807123 rs1216481372	568	M>I		No	ClinGen TOPMed gnomAD
rs1200969926 CA356807153	573	T>P		No	ClinGen gnomAD
CA2908502 rs369919671	579	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA356807206 rs1577678685	580	E>G		No	ClinGen Ensembl
CA96634934 rs575685869	582	L>S		No	ClinGen 1000Genomes gnomAD
CA356807217 rs1181976647	582	L>V		No	ClinGen gnomAD
CA356807224 rs1337806910	583	Y>D		No	ClinGen TOPMed
rs748032488 CA2908504	584	I>S		No	ClinGen ExAC TOPMed gnomAD
CA2908503 rs142365853	584	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA96634962 rs200334720	585	I>T		No	ClinGen gnomAD
CA356807236 rs1560441760 COSM587403	585	I>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
rs377124199 CA356807247	586	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908506 COSM279042 rs561130132	586	D>N	lung Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA356807251 rs1463340200	587	F>Y		No	ClinGen TOPMed
CA356807265 rs1332916523	589	I>V		No	ClinGen gnomAD
rs1170208436 CA356807291	593	I>V		No	ClinGen TOPMed
rs759295483 CA2908510	596	T>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1233865444 CA356807318	597	V>I		No	ClinGen gnomAD
CA356807324 rs1321114603	598	V>M		No	ClinGen gnomAD
CA2908512 rs774990884	599	V>A		No	ClinGen ExAC gnomAD
rs140450965 CA356807342	601	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908513 rs140450965	601	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	601	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1195444237 CA356807351	602	P>L		No	ClinGen gnomAD
rs1435036339 CA356807354	603	N>D		No	ClinGen gnomAD
rs1200193047 CA356807356	603	N>S		No	ClinGen gnomAD
CA96634982 rs988706879	604	Q>E		No	ClinGen TOPMed gnomAD
rs1469634346 CA356807371	605	P>L		No	ClinGen TOPMed
rs201010617 CA2908514	606	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs369968292 CA2908515	606	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs183792861 CA96634990	608	K>R		No	ClinGen 1000Genomes
rs769505364 CA2908528	610	R>G		No	ClinGen ExAC gnomAD
rs1187065212 CA356807409 COSM1055717	610	R>K	Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs774937862 CA2908529	611	H>Q		No	ClinGen ExAC gnomAD
CA96636152 rs894272887	612	P>S		No	ClinGen Ensembl
CA356807437 rs1401699385	615	G>E		No	ClinGen gnomAD
CA2908532 CA2908534 rs374331628	615	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs374331628 CA2908533	615	G>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA356807443 rs1296683648	616	G>V		No	ClinGen TOPMed
CA96636188 rs949177657	616	G>W		No	ClinGen TOPMed gnomAD
CA356807451 rs1293671072	617	L>F		No	ClinGen gnomAD
TCGA novel	620	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1225860607 CA356807487	623	E>Q		No	ClinGen TOPMed
CA2908536 rs773640259	624	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1577681490 CA356807496	624	E>Q		No	ClinGen Ensembl
rs760760650 CA2908537	625	I>V		No	ClinGen ExAC gnomAD
rs766741560 CA2908538	626	K>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	629	F>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908539 rs754142382	631	R>G		No	ClinGen ExAC gnomAD
rs1385811209 CA356807545	631	R>K		No	ClinGen TOPMed
CA2908540 rs777603269	635	R>*		No	ClinGen ExAC TOPMed gnomAD
CA2908541 rs777603269	635	R>G		No	ClinGen ExAC TOPMed gnomAD
rs202127870 CA2908542	635	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA2908543 rs150390133	636	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA356807580 rs1167159200	637	S>P		No	ClinGen TOPMed
CA2908544 rs780831455	638	S>G		No	ClinGen ExAC gnomAD
CA356807587 rs1451745473	638	S>N		No	ClinGen TOPMed
rs552234860 CA2908545	640	P>L		No	ClinGen 1000Genomes ExAC gnomAD
CA2908546 rs755937043	641	S>L		No	ClinGen ExAC TOPMed gnomAD
CA2908548 rs377407484	642	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908549 rs768089566	642	L>P		No	ClinGen ExAC gnomAD
rs773977729 CA2908550	643	N>S		No	ClinGen ExAC TOPMed gnomAD
CA356807626 rs1451571014	644	S>R		No	ClinGen gnomAD
CA96636308 rs1006327870	648	P>S		No	ClinGen Ensembl
CA2908552 rs772682363	651	G>R		No	ClinGen ExAC gnomAD
TCGA novel	653	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96636315 rs111616775	654	N>D		No	ClinGen TOPMed gnomAD
CA2908554 rs768333726	655	A>T		No	ClinGen ExAC TOPMed gnomAD
CA356807708 rs1285076156	657	V>G		No	ClinGen gnomAD
rs1316807130 CA356807712	658	S>G		No	ClinGen gnomAD
rs1214277373 CA356807720	659	R>K		No	ClinGen gnomAD
rs1214277373 CA356807721	659	R>T		No	ClinGen gnomAD
rs1344047708 CA356807729	660	L>P		No	ClinGen TOPMed
CA2908556 rs373967400	661	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908557 rs373967400	661	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908558 rs765398868	662	L>I		No	ClinGen ExAC TOPMed gnomAD
CA356807739 rs1240935472	662	L>R		No	ClinGen gnomAD
rs142235555 CA96636348	665	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908560 rs146116655	665	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
COSM3696794 CA2908561 rs146116655	665	R>Q	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs1349287195 CA356807759	666	M>V		No	ClinGen TOPMed
rs374215434 CA2908565	668	P>L		No	ClinGen ESP ExAC gnomAD
CA2908564 rs374215434	668	P>Q		No	ClinGen ESP ExAC gnomAD
rs1432092677 CA356807780	669	A>P		No	ClinGen TOPMed
TCGA novel	669	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	670	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908566 rs187355739	671	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908567 rs187355739	671	P>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs558782821 CA96636386	672	V>A		No	ClinGen TOPMed
rs1404114541 CA356807795	672	V>M		No	ClinGen gnomAD
CA356807811 rs1199731546	674	E>A		No	ClinGen TOPMed
CA2908569 rs778264598	676	V>I		No	ClinGen ExAC gnomAD
rs1372712477 CA356807831	677	S>P		No	ClinGen gnomAD
TCGA novel	678	Q>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356807855 rs1560443768	680	C>W		No	ClinGen Ensembl
rs201572653 CA96636434	680	C>Y		No	ClinGen TOPMed gnomAD
rs1447271327 CA356807862	681	E>D		No	ClinGen gnomAD
TCGA novel	682	S>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908571 rs149296162	682	S>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA2908572 rs199600119	683	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA356807883 rs1446301761	684	Q>H		No	ClinGen Ensembl
TCGA novel	684	Q>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771352321 CA2908574	686	S>F		No	ClinGen ExAC TOPMed gnomAD
CA2908575 rs777199623	687	S>G		No	ClinGen ExAC gnomAD
rs759814894 CA2908576	687	S>N		No	ClinGen ExAC gnomAD
CA2908577 rs770185124	691	C>R		No	ClinGen ExAC gnomAD
rs775609445 CA2908578	692	C>W		No	ClinGen ExAC gnomAD
rs763041773 CA2908579	694	E>D		No	ClinGen ExAC gnomAD
rs1173935058 CA356807962	696	E>D		No	ClinGen gnomAD
TCGA novel	697	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs568662009 CA2908581	698	Q>E		No	ClinGen 1000Genomes ExAC gnomAD
rs568662009 CA2908582	698	Q>K		No	ClinGen 1000Genomes ExAC gnomAD
rs1257420954 CA356807975	698	Q>R		No	ClinGen TOPMed
CA96636472 rs968849661	699	H>R		No	ClinGen TOPMed gnomAD
CA356807980 rs1329856036	699	H>Y		No	ClinGen TOPMed gnomAD
CA96636477 rs977212677	700	G>S		No	ClinGen TOPMed gnomAD
CA96636479 rs924239323	701	D>A		No	ClinGen Ensembl
CA2908584 rs753682058	702	A>T		No	ClinGen ExAC TOPMed gnomAD
rs201846331 CA2908585	703	G>A		No	ClinGen 1000Genomes ExAC gnomAD
rs201846331 CA2908586	703	G>D		No	ClinGen 1000Genomes ExAC gnomAD
rs201846331 CA356808005	703	G>V		No	ClinGen 1000Genomes ExAC gnomAD
CA96636500 rs959700331	704	L>F		No	ClinGen Ensembl
rs752313490 CA2908587	704	L>H		No	ClinGen ExAC gnomAD
CA96636512 rs990505011	707	G>D		No	ClinGen TOPMed gnomAD
CA2908588 rs200916542	707	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA96636515 rs992491743	709	A>T		No	ClinGen TOPMed
rs1223062898 CA356808042	710	E>K		No	ClinGen gnomAD
rs1223062898 CA356808040	710	E>Q		No	ClinGen gnomAD
TCGA novel	711	S>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM734317 CA2908589 rs143517951	711	S>F	lung [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs1577682031 CA356808058	712	L>P		No	ClinGen Ensembl
CA2908590 rs147997626	715	Q>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA356808078 rs34208443	716	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908592 rs781668803 COSM339172	716	P>L	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
VAR_048391 rs34208443 CA2908591	716	P>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1328359352 CA356808085	717	L>S		No	ClinGen gnomAD
rs555216718 CA96636536	719	C>R		No	ClinGen Ensembl
VAR_048392 rs34169638 CA2908593	720	N>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1168683708 CA356808110	721	L>V		No	ClinGen gnomAD
rs369950538 CA96636541	724	E>D		No	ClinGen 1000Genomes ExAC gnomAD
CA356808130 rs1419141118	724	E>K		No	ClinGen gnomAD
rs909732631 CA356808143	726	E>K		No	ClinGen TOPMed gnomAD
rs909732631 CA96636553	726	E>Q		No	ClinGen TOPMed gnomAD
rs936551540 CA96636554	727	S>N		No	ClinGen TOPMed gnomAD
rs139768206 CA2908598	730	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA96636559 rs112408159	731	A>T		No	ClinGen Ensembl
rs371299383 CA2908599	731	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs753802742 CA2908601	733	L>F		No	ClinGen ExAC gnomAD
CA356808196 rs1266937748	734	V>L		No	ClinGen TOPMed gnomAD
rs1266937748 CA356808194	734	V>M		No	ClinGen TOPMed gnomAD
CA356808204 rs1342640224	735	Y>C		No	ClinGen TOPMed
rs932629300 CA96636563	736	A>V		No	ClinGen TOPMed
rs374921883 CA2908604	737	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908603 rs374921883	737	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA356808224 rs1447346324	739	A>S		No	ClinGen TOPMed gnomAD
rs1240177496 CA356808235	740	Y>F		No	ClinGen gnomAD
CA356808259 rs1185673663	743	T>I		No	ClinGen gnomAD
rs1162198061 CA356808269	745	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs368001466 CA2908605	745	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs1471734347 CA356808275	746	S>C		No	ClinGen TOPMed
CA356808272 rs1387713450	746	S>P		No	ClinGen gnomAD
rs756861814 CA2908609	747	R>G		No	ClinGen ExAC TOPMed gnomAD
rs146146861 CA96636592	747	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA TOPMed gnomAD
rs756861814 CA2908608	747	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA96636608 rs113146367	752	V>A		No	ClinGen Ensembl
rs1454230675 CA356808313	753	M>V		No	ClinGen gnomAD
rs756436780 CA2908611	755	D>N		No	ClinGen ExAC gnomAD
CA356808335 rs1560444213	756	F>L		No	ClinGen Ensembl
CA356808338 rs1464982293	756	F>S		No	ClinGen TOPMed
rs375583564 CA2908612	757	A>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA356808346 rs1560444234	757	A>V		No	ClinGen Ensembl
rs200095375 CA2908614	760	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356808367 rs1351263870	761	P>S		No	ClinGen gnomAD
CA356808365 rs1351263870	761	P>T		No	ClinGen gnomAD
rs1285199096 CA356808383	763	T>I		No	ClinGen TOPMed
TCGA novel	767	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768407090 CA96636629	768	H>P		No	ClinGen Ensembl
CA96636634 rs1012032831	771	P>S		No	ClinGen TOPMed
rs1391680586 CA356808456	774	S>L		No	ClinGen gnomAD
CA2908619 rs776492459	775	V>A		No	ClinGen ExAC gnomAD
CA2908620 rs764990155	780	S>ATQI*		No	ClinGen ExAC
CA2908621 rs750041884	782	V>Q		No	ClinGen ExAC
CA2908623 rs74552892	784	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA356808519 rs796765340	784	R>P		No	ClinGen TOPMed gnomAD
rs796765340 CA96636646	784	R>Q		No	ClinGen TOPMed gnomAD
rs1349388348 CA356808526	785	H>Q		No	ClinGen TOPMed
rs1031416276 CA96636650	786	P>L		No	ClinGen TOPMed gnomAD
rs1470764324 CA356808533	787	L>V		No	ClinGen gnomAD
rs541304180 CA2908624	789	N>H		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	790	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356808568 rs1286311938	792	V>L		No	ClinGen TOPMed
rs751282807 CA2908627	793	V>A		No	ClinGen ExAC gnomAD
rs149814216 CA2908626	793	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs149814216 CA356808572	793	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908628 rs756771703	794	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA2908629 rs767141536	795	T>M		No	ClinGen ExAC gnomAD
CA356808583 rs1245693955	795	T>P		No	ClinGen TOPMed
CA356808592 rs1326405821	796	K>R		No	ClinGen TOPMed gnomAD
rs780443888 CA2908632	798	A>T		No	ClinGen ExAC TOPMed gnomAD
rs749654029 CA2908633	800	S>A		No	ClinGen ExAC gnomAD
CA2908634 rs755400903	803	M>V		No	ClinGen ExAC gnomAD
COSM279043 CA2908635 rs145762869	807	S>L	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA2908638 rs772070379	808	V>L		No	ClinGen ExAC TOPMed gnomAD
CA2908637 rs772070379	808	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1438529223 CA356808672	809	A>S		No	ClinGen gnomAD
rs76810881 CA96636728	810	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA2908639 rs745800917	811	P>A		No	ClinGen ExAC TOPMed
rs267600170 CA96636746	811	P>L		No	ClinGen Ensembl
CA356808714 rs1380576628	814	A>V		No	ClinGen Ensembl
rs879317697 CA96637075	815	S>T		No	ClinGen Ensembl
CA356808724 rs1200800874	816	L>M		No	ClinGen gnomAD
CA356808725 rs1200800874	816	L>V		No	ClinGen gnomAD
CA2908655 rs777803503	817	E>A		No	ClinGen ExAC TOPMed gnomAD
CA356808734 rs1341152822	817	E>D		No	ClinGen TOPMed
rs377230023 CA2908654	817	E>K		No	ClinGen ESP ExAC TOPMed
CA2908656 rs747095677	819	Q>R		No	ClinGen ExAC gnomAD
CA356808800 rs1161836013	826	K>I		No	ClinGen gnomAD
rs779801543 CA2908658	828	Q>*		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	828	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356808812 rs1165585596	828	Q>R		No	ClinGen gnomAD
CA356808824 rs749255964	830	H>N		No	ClinGen ExAC TOPMed gnomAD
rs768568217 CA2908660	830	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA2908659 rs749255964	830	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA2908661 rs774348386	831	L>S		No	ClinGen ExAC TOPMed gnomAD
rs895999196 CA96637128	831	L>V		No	ClinGen Ensembl
CA2908662 rs761536056	832	D>G		No	ClinGen ExAC gnomAD
CA2908664 rs772948636	833	D>E		No	ClinGen ExAC gnomAD
CA356808857 rs1276798692	835	A>T		No	ClinGen Ensembl
CA356808870 rs1306613768	836	K>N		No	ClinGen TOPMed
rs1327211280 CA356808881	838	G>C		No	ClinGen gnomAD
rs1560444953 CA356808888	839	L>H		No	ClinGen Ensembl
CA2908665 rs760054397	840	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs765924864 CA2908666	840	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs754230088 CA2908667	843	C>R		No	ClinGen ExAC gnomAD
CA2908668 rs760099733	845	A>P		No	ClinGen ExAC TOPMed gnomAD
rs1560444985 CA356808935	847	K>Q		No	ClinGen Ensembl
rs1246866348 CA356808956	848	V>I		No	ClinGen gnomAD
CA356808963 rs138361998	849	M>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2908687 rs138361998	849	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1047121089 CA96638098	850	S>N		No	ClinGen Ensembl
rs1358252847 CA356808970	850	S>R		No	ClinGen TOPMed
rs1320373884 CA356808977	851	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA2908688 rs776005074	852	T>P		No	ClinGen ExAC gnomAD
TCGA novel	853	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1485783508 CA356809007	855	A>P		No	ClinGen gnomAD
rs1485783508 CA356809006	855	A>T		No	ClinGen gnomAD
CA356809020 rs1206402618	857	W>R		No	ClinGen gnomAD
rs1244645439 CA356809029	858	L>M		No	ClinGen gnomAD
TCGA novel	858	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908690 rs764528510	859	R>G		No	ClinGen ExAC gnomAD
CA2908691 rs751728626	859	R>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	859	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908692 rs757559049	860	N>D		No	ClinGen ExAC gnomAD
CA356809059 rs1420746815	862	F>C		No	ClinGen gnomAD
rs147675892 CA2908693	867	S>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs147675892 CA356809093	867	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908694 rs750571239	868	I>V		No	ClinGen ExAC gnomAD
rs1318759213 CA356809135	873	E>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA2908695 rs756293578	876	L>F		No	ClinGen ExAC gnomAD
rs1347388222 CA356809158	877	E>K		No	ClinGen TOPMed
rs142329918 CA2908697	880	M>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908696 rs778944480	880	M>T		No	ClinGen ExAC gnomAD
rs1577685570 CA356809199	883	E>K		No	ClinGen Ensembl
rs758198011 CA2908698	884	N>D		No	ClinGen ExAC gnomAD
rs1308381593 CA356809224	886	L>F		No	ClinGen gnomAD
CA2908699 rs777689738	887	T>A		No	ClinGen ExAC TOPMed gnomAD
rs746625584 CA2908700	887	T>I		No	ClinGen ExAC gnomAD
rs746625584 CA356809230	887	T>K		No	ClinGen ExAC gnomAD
rs1461439449 CA356809232	888	L>I		No	ClinGen gnomAD
CA356809275 rs1175073653	893	G>C		No	ClinGen TOPMed
rs984988802 CA96639592	894	I>V		No	ClinGen gnomAD
CA96639595 rs573220898	895	E>G		No	ClinGen gnomAD
rs1454371202 CA356809285	895	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1190803902 COSM1184004 CA356809302	897	R>C	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
rs746857968 CA2908720	897	R>H		No	ClinGen ExAC TOPMed gnomAD
rs746857968 CA2908721	897	R>L		No	ClinGen ExAC TOPMed gnomAD
CA356809339 rs1251793068	903	P>S		No	ClinGen TOPMed
CA2908724 rs769294120	906	I>T		No	ClinGen ExAC TOPMed gnomAD
CA356809358 rs1428370586	906	I>V		No	ClinGen gnomAD
CA356809376 rs1346511561	908	A>V		No	ClinGen TOPMed gnomAD
rs147847026 CA2908725	910	H>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA356809395 rs1273466768	911	K>I		No	ClinGen gnomAD
CA96639607 rs200004371	912	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
TCGA novel	913	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96639608 rs903422570	914	I>V		No	ClinGen TOPMed
rs1271663804 CA356809427	916	I>T		No	ClinGen gnomAD
CA2908727 rs769247728	918	M>L		No	ClinGen ExAC TOPMed gnomAD
rs774752451 CA2908728	921	G>E		No	ClinGen ExAC gnomAD
rs543298578 CA96639620	923	K>Q		No	ClinGen 1000Genomes
CA356809482 rs1490171560	924	Q>R		No	ClinGen gnomAD
rs762188924 CA2908729	925	E>A		No	ClinGen ExAC TOPMed gnomAD
CA356809488 rs762188924	925	E>G		No	ClinGen ExAC TOPMed gnomAD
rs914530009 CA96639623	925	E>Q		No	ClinGen Ensembl
rs1243636611 CA356809496	926	T>R		No	ClinGen gnomAD
rs371722384 CA2908731	928	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908732 rs761045453	929	N>D		No	ClinGen ExAC gnomAD
rs1314371912 CA356809512	929	N>S		No	ClinGen TOPMed
rs1447780613 CA356809520	930	I>T		No	ClinGen gnomAD
rs754016049 CA2908734	933	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1041556197 CA96639634	933	A>V		No	ClinGen Ensembl
CA356809542 rs1156314506	934	C>R		No	ClinGen TOPMed
CA2908735 rs762763809	935	K>E		No	ClinGen ExAC gnomAD
rs1227461430 CA356809585	940	D>E		No	ClinGen TOPMed gnomAD
rs757014135 CA2908738	940	D>N		No	ClinGen ExAC gnomAD
CA2908739 rs781034898	942	K>*		No	ClinGen ExAC gnomAD
rs781034898 CA356809596	942	K>Q		No	ClinGen ExAC gnomAD
rs750067673 CA2908740	943	L>F		No	ClinGen ExAC TOPMed gnomAD
rs996516884 CA96639652	948	T>A		No	ClinGen TOPMed
rs1207999725 CA356809649	950	S>R		No	ClinGen gnomAD
rs1295127182 CA356809658	951	K>E		No	ClinGen gnomAD
CA356809686 rs1315562617	953	A>T		No	ClinGen Ensembl
CA356809696 rs1441954415	954	C>S		No	ClinGen gnomAD
CA2908761 rs543911299	956	M>K		No	ClinGen 1000Genomes ExAC gnomAD
rs754442232 CA2908763	958	M>T		No	ClinGen ExAC gnomAD
CA2908764 rs17462252 VAR_048393	959	S>N		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1410227429 CA356809737	960	T>I		No	ClinGen gnomAD
CA356809739 rs1410227429	960	T>K		No	ClinGen gnomAD
rs199756910 CA2908765	961	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA356809751 rs1356644065	962	L>F		No	ClinGen TOPMed
CA356809773 rs1329913022	965	L>P		No	ClinGen TOPMed
CA2908766 rs368388765	966	Q>E		No	ClinGen ESP ExAC gnomAD
CA356809802 rs778247674	969	T>I		No	ClinGen ExAC TOPMed gnomAD
CA2908767 rs778247674	969	T>S		No	ClinGen ExAC TOPMed gnomAD
rs747333512 CA2908768	970	Q>*		No	ClinGen ExAC gnomAD
rs1178722673 CA356809816	972	L>M		No	ClinGen TOPMed
rs1409139438 CA356809821	973	P>T		No	ClinGen TOPMed gnomAD
CA356809842 rs1286164643	975	Q>H		No	ClinGen gnomAD
rs1225545531 CA356809862	979	S>G		No	ClinGen gnomAD
rs746146079 CA2908771	979	S>R		No	ClinGen ExAC TOPMed gnomAD
CA356809881 rs1000995997	981	D>A		No	ClinGen TOPMed
CA96641866 rs1000995997	981	D>G		No	ClinGen TOPMed
CA2908772 rs769906876	983	L>P		No	ClinGen ExAC gnomAD
CA356809910 rs1198762320	985	P>L		No	ClinGen gnomAD
rs1198988721 CA356809906	985	P>S		No	ClinGen TOPMed
CA2908773 rs137994896	987	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs137994896 CA356809917	987	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908774 rs137994896	987	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908778 rs760406341	988	P>R		No	ClinGen ExAC
CA2908777 rs773155936	988	P>S		No	ClinGen ExAC gnomAD
rs753524004 CA356809925	989	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA2908781 rs754642932	989	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs753524004 CA2908780	989	R>W		No	ClinGen ExAC TOPMed gnomAD
CA2908782 rs764782844	990	D>H		No	ClinGen ExAC TOPMed gnomAD
rs1396613226 CA356809940	991	S>L		No	ClinGen gnomAD
TCGA novel	993	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200863114 CA2908784	994	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA2908786 rs147568390	994	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs147568390 CA356809957	994	R>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs147568390 CA2908785	994	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	995	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908788 rs757625655	996	G>A		No	ClinGen ExAC gnomAD
CA2908787 rs757625655	996	G>V		No	ClinGen ExAC gnomAD
CA356809989 rs1466694912	997	L>F		No	ClinGen TOPMed
CA356810003 rs1344693454	998	I>V		No	ClinGen TOPMed
CA356810022 rs1560450614	999	I>T		No	ClinGen Ensembl
rs1389012626 CA356810035	1000	T>N		No	ClinGen gnomAD
rs866286118 CA96641947	1001	G>W		No	ClinGen Ensembl
rs769954709 CA2908790	1002	K>R		No	ClinGen ExAC gnomAD
rs1231349219 CA356810070	1003	T>I		No	ClinGen gnomAD
CA356810075 rs144659641	1004	L>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908791 rs144659641	1004	L>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA356810119 rs1205040394	1007	A>S		No	ClinGen gnomAD
rs768736337 CA356810130	1008	L>M		No	ClinGen ExAC gnomAD
CA356810135 rs1417264372	1008	L>P		No	ClinGen TOPMed
rs768736337 CA2908793	1008	L>V		No	ClinGen ExAC gnomAD
CA356810169 rs1179067660	1010	E>D		No	ClinGen TOPMed
rs1490991214 CA356810165	1010	E>G		No	ClinGen TOPMed gnomAD
rs1490991214 CA356810167	1010	E>V		No	ClinGen TOPMed gnomAD
rs773068101 CA2908794	1015	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs372690498 CA2908795	1015	Q>P		No	ClinGen ESP ExAC gnomAD
rs372690498 CA356810227	1015	Q>R		No	ClinGen ESP ExAC gnomAD
CA2908797 rs776339727	1016	F>L		No	ClinGen ExAC
rs759195174 CA2908798	1018	E>K		No	ClinGen ExAC gnomAD
rs201412941 CA2908799	1019	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs752412350 CA2908800	1021	S>P		No	ClinGen ExAC gnomAD
CA356810312 rs1166196070	1022	W>*		No	ClinGen gnomAD
rs1367324670 CA356810317	1023	C>G		No	ClinGen gnomAD
rs1372854029 CA356810323	1023	C>Y		No	ClinGen gnomAD
TCGA novel	1027	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs752102562 CA356810435	1030	R>*		No	ClinGen ExAC gnomAD
rs752102562 CA2908803	1030	R>G		No	ClinGen ExAC gnomAD
rs138541186 CA2908804	1030	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA356810483 rs1289032538	1033	P>L		No	ClinGen Ensembl
CA356810493 rs1231233404	1034	L>R		No	ClinGen TOPMed gnomAD
CA2908806 rs202123877	1037	S>G		No	ClinGen ExAC TOPMed gnomAD
rs1362139707 CA356810589	1041	K>Q		No	ClinGen gnomAD
rs565285972 CA96642077	1043	V>I		No	ClinGen 1000Genomes
rs532632251 CA2908808	1044	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs749518084 CA2908809	1044	R>H		No	ClinGen ExAC TOPMed gnomAD
CA356810650 rs749518084	1044	R>P		No	ClinGen ExAC TOPMed gnomAD
CA2908810 rs768719800	1045	S>G		No	ClinGen ExAC TOPMed gnomAD
CA96642087 rs937038620	1046	H>N		No	ClinGen TOPMed
CA2908811 rs779020702	1047	L>F		No	ClinGen ExAC gnomAD
CA2908812 rs188036119	1048	Q>H		No	ClinGen 1000Genomes ExAC gnomAD
rs568892444 CA2908813	1049	V>M		No	ClinGen 1000Genomes ExAC gnomAD
rs776661621 CA2908814	1050	M>I		No	ClinGen ExAC TOPMed gnomAD
CA356810749 rs1159192186	1051	T>I		No	ClinGen TOPMed
CA2908816 rs193079887	1052	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908833 rs372999962	1055	G>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908832 rs372999962	1055	G>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA2908834 rs769469125	1056	D>E		No	ClinGen ExAC
TCGA novel	1057	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356811041 rs1292718743	1058	A>T		No	ClinGen gnomAD
rs775477328 CA2908835	1058	A>V	Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1226154872 CA356811047	1059	N>D		No	ClinGen gnomAD
rs200697091 CA2908836	1060	D>E		No	ClinGen 1000Genomes ExAC gnomAD
rs1312435031 CA356811069	1062	S>N		No	ClinGen TOPMed gnomAD
CA356811075 rs1208769164	1063	M>V		No	ClinGen gnomAD
rs768386807 CA2908837	1064	I>M		No	ClinGen ExAC gnomAD
CA356811098 rs1160543659	1066	V>L		No	ClinGen TOPMed
CA356811115 rs1470606512	1068	D>E		No	ClinGen TOPMed
rs1481542324 CA356811109	1068	D>N		No	ClinGen gnomAD
CA356811118 rs1368019013	1069	I>V		No	ClinGen TOPMed
CA356811127 rs1182887197	1070	G>E		No	ClinGen gnomAD
CA356811140 rs1471512221	1072	G>E		No	ClinGen gnomAD
CA96646859 rs907291448	1073	V>F		No	ClinGen TOPMed gnomAD
rs907291448 CA356811143	1073	V>I		No	ClinGen TOPMed gnomAD
CA2908838 rs774174090	1076	Q>P		No	ClinGen ExAC gnomAD
CA356811163 rs774174090	1076	Q>R		No	ClinGen ExAC gnomAD
CA2908840 COSM1670999 rs761170058 CA356811200	1079	M>I	lung [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA2908841 rs767060029	1080	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs1016794326 CA96647578	1081	A>T		No	ClinGen Ensembl
rs1435308458 CA356811358	1084	A>S		No	ClinGen gnomAD
rs1463943693 CA356811374	1085	S>N		No	ClinGen TOPMed
rs182459999 CA96647584	1087	F>L		No	ClinGen 1000Genomes
rs376165524 CA2908863	1089	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs376165524 CA96647619	1089	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA96647623 rs993482092	1091	Q>*		No	ClinGen gnomAD
rs777145546 CA2908864	1091	Q>H		No	ClinGen ExAC gnomAD
rs759832169 CA2908865	1092	F>I		No	ClinGen ExAC
rs1452868814 CA356811487	1093	K>R		No	ClinGen TOPMed
rs765587732 CA2908867	1099	L>I		No	ClinGen ExAC gnomAD
rs148784624 CA356811606	1102	H>D		No	ClinGen ESP ExAC gnomAD
rs148784624 CA2908870	1102	H>N		No	ClinGen ESP ExAC gnomAD
rs751621741 CA2908871	1102	H>P		No	ClinGen ExAC gnomAD
CA356811618 rs757438980	1102	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA356811644 rs1448190877	1104	H>R		No	ClinGen TOPMed gnomAD
CA2908873 rs780086835	1105	W>*		No	ClinGen ExAC gnomAD
CA2908874 rs749242976	1105	W>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1209884622 CA356811654	1105	W>R		No	ClinGen TOPMed
rs778911658 CA2908877 COSM1186565	1109	R>W	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs868689531 CA96647711	1111	S>T		No	ClinGen Ensembl
rs747735220 CA2908878	1112	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA2908879 rs771795320	1114	I>V		No	ClinGen ExAC TOPMed gnomAD
CA356811800 rs1184910645	1115	L>F		No	ClinGen TOPMed gnomAD
CA356811798 rs1184910645	1115	L>V		No	ClinGen TOPMed gnomAD
CA2908880 rs141533238	1116	Y>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1117	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746477757 CA2908881	1120	K>Q		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1120	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777051830 CA356811902	1121	N>K		No	ClinGen ExAC TOPMed gnomAD
CA2908882 rs371072531	1121	N>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs778542947 CA2908895	1124	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs778542947 CA356812078	1124	Y>F		No	ClinGen ExAC TOPMed gnomAD
rs1289969697 CA356812090	1126	N>Y		No	ClinGen gnomAD
CA2908896 rs548527000	1130	W>*		No	ClinGen 1000Genomes ExAC gnomAD
CA96650419 rs780175920	1130	W>R		No	ClinGen TOPMed gnomAD
rs758149277 CA2908897	1132	Q>P		No	ClinGen ExAC gnomAD
CA2908898 COSM1055722 rs777425761	1133	F>L	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
TCGA novel	1135	C>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356812192 rs1442335423	1140	T>I		No	ClinGen TOPMed gnomAD
CA356812225 rs1471185314	1145	Y>C		No	ClinGen TOPMed
CA96650456 rs113342735	1145	Y>H		No	ClinGen Ensembl
rs139349772 CA2908902	1147	V>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2908901 rs373789759	1147	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA356812258 rs1473150805	1150	F>V		No	ClinGen gnomAD
CA356812271 rs1468797852	1151	F>L		No	ClinGen TOPMed
rs775887388 CA2908904	1152	N>S		No	ClinGen ExAC TOPMed gnomAD
rs145477523 CA2908905	1153	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA96650491 rs532360506	1154	L>P		No	ClinGen Ensembl
rs768910963 CA2908906	1156	T>A		No	ClinGen ExAC gnomAD
CA2908907 rs774629337	1156	T>I		No	ClinGen ExAC gnomAD
rs1441862262 CA356812317	1159	P>L		No	ClinGen TOPMed
CA2908908 rs762184323	1161	V>A		No	ClinGen ExAC TOPMed gnomAD
rs767684890 CA2908909	1162	I>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA356812340 rs1408944862	1163	Y>C		No	ClinGen TOPMed gnomAD
CA356812339 rs1408944862	1163	Y>S		No	ClinGen TOPMed gnomAD
TCGA novel	1166	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA96650512 rs916389468	1167	E>K		No	ClinGen Ensembl
CA356812383 rs1275505013	1169	D>E		No	ClinGen TOPMed gnomAD
CA2908911 rs750573173	1169	D>N		No	ClinGen ExAC TOPMed gnomAD
rs1235768737 CA356812380	1169	D>V		No	ClinGen gnomAD
rs760867195 CA2908912	1170	V>L		No	ClinGen ExAC TOPMed gnomAD
rs760867195 CA356812385	1170	V>M		No	ClinGen ExAC TOPMed gnomAD
CA356812398 rs1209322214	1172	A>E		No	ClinGen gnomAD
rs112973469 CA96650551	1172	A>T		No	ClinGen Ensembl
CA2908913 rs765171447	1175	L>F		No	ClinGen ExAC gnomAD
rs1204800239 CA356812433	1177	Q>R		No	ClinGen gnomAD
rs16851681 VAR_048394 CA2908915	1183	R>K		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA96650605 rs768976888	1186	Q>E		No	ClinGen TOPMed gnomAD
rs370383541 CA2908916	1188	S>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1476784491 CA356812515	1189	E>D		No	ClinGen gnomAD
rs751195786 CA2908917	1189	E>K		No	ClinGen ExAC
TCGA novel	1189	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767100122 CA2908939	1193	P>S		No	ClinGen ExAC gnomAD
CA356812562 rs1322625448	1194	H>Q		No	ClinGen gnomAD
rs367938126 CA2908941	1196	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1366110011 CA356812573	1196	F>S		No	ClinGen gnomAD
rs749783360 CA2908943	1200	L>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1202	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1265235691 CA356812622	1203	A>G		No	ClinGen gnomAD
CA2908945 rs779597466	1205	Y>C		No	ClinGen ExAC gnomAD
CA356812635 rs779597466	1205	Y>F		No	ClinGen ExAC gnomAD
rs756110526 CA2908944	1205	Y>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1205	Y>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM4135794 rs1248068977 CA356812640	1206	Q>E	ovary [Cosmic]	No	ClinGen cosmic curated gnomAD
CA356812639 rs1248068977	1206	Q>K		No	ClinGen gnomAD
CA2908946 rs748472082	1207	S>R		No	ClinGen ExAC TOPMed gnomAD
rs1214135241 CA356812655	1208	L>V		No	ClinGen TOPMed
rs1326952580 CA356812665	1210	C>G		No	ClinGen gnomAD
rs1184275465 CA356812676	1211	F>Y		No	ClinGen gnomAD
CA356812693 rs1255824094	1213	V>A		No	ClinGen TOPMed
rs772575410 CA2908947	1216	F>L		No	ClinGen ExAC gnomAD
rs1280164274 CA356812742	1217	T>A		No	ClinGen TOPMed gnomAD
rs1214459150 CA356812754	1218	Y>C		No	ClinGen TOPMed
rs753249993 CA2908961	1218	Y>H		No	ClinGen ExAC gnomAD
CA96653460 rs144576632	1219	Q>*		No	ClinGen ESP ExAC gnomAD
CA2908963 rs144576632	1219	Q>E		No	ClinGen ESP ExAC gnomAD
rs149003357 CA2908964	1220	G>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs758828166 CA2908965	1222	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
COSM1495764 rs1302821257 CA356812811	1223	T>I	kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA96653465 rs760164138	1224	D>E		No	ClinGen Ensembl
rs371755728 CA96653466	1225	I>V		No	ClinGen ESP
rs1374190568 CA356812839	1226	F>Y		No	ClinGen TOPMed gnomAD
rs1560458023 CA356812861	1228	F>L		No	ClinGen Ensembl
CA356812893 rs1577708375	1230	N>K		No	ClinGen Ensembl
rs1199907836 CA356812891	1230	N>T		No	ClinGen TOPMed
CA2908967 rs565136756	1231	P>H		No	ClinGen 1000Genomes ExAC gnomAD
CA356812903 rs565136756	1231	P>R		No	ClinGen 1000Genomes ExAC gnomAD
CA356812897 rs1412017550	1231	P>T		No	ClinGen gnomAD
rs375013581 CA2908968	1233	N>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs375013581 CA356812920	1233	N>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1001170350 CA96653476	1234	T>I		No	ClinGen Ensembl
CA356812926 rs1221771172	1234	T>P		No	ClinGen gnomAD
rs762466294 CA2908970	1236	A>T		No	ClinGen ExAC TOPMed gnomAD
rs769868948 CA2908971	1236	A>V		No	ClinGen ExAC gnomAD
rs761798082 CA2908973	1237	L>V		No	ClinGen ExAC TOPMed gnomAD
rs200439351 CA2908976	1240	V>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
VAR_020187 rs1058793 CA2908975	1240	V>I		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
TCGA novel	1242	L>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1175774910 CA356813013	1242	L>F		No	ClinGen gnomAD
rs765901941 CA356813028	1243	H>L		No	ClinGen ExAC TOPMed gnomAD
rs765901941 CA2908977	1243	H>P		No	ClinGen ExAC TOPMed gnomAD
rs1433792203 CA356813051	1246	I>V		No	ClinGen gnomAD
CA96653513 rs1025468444	1248	S>T		No	ClinGen TOPMed
rs753538738 CA2908978	1249	K>R		No	ClinGen ExAC gnomAD
rs375191152 CA96653528 COSM4135795	1251	L>F	ovary [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
TCGA novel	1255	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1258	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1260	I>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776140901 CA2908996	1260	I>T		No	ClinGen ExAC TOPMed gnomAD
CA356813512 rs1359813790	1260	I>V		No	ClinGen gnomAD
TCGA novel	1262	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2908997 rs200363788	1264	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA356813537 rs1290341699	1264	L>M		No	ClinGen gnomAD
CA356813540 rs1478154469	1264	L>S		No	ClinGen TOPMed
rs1247555474 CA356813569	1268	L>*		No	ClinGen TOPMed
CA356813572 rs1204235586	1269	F>I		No	ClinGen TOPMed
rs764814212 CA2908998	1271	I>T		No	ClinGen ExAC gnomAD
TCGA novel	1273	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356813609 rs1271318523	1274	G>E		No	ClinGen gnomAD
CA2908999 rs752294717	1275	A>V		No	ClinGen ExAC gnomAD
CA2909001 rs764644710	1277	C>F		No	ClinGen ExAC gnomAD
TCGA novel	1279	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2909002 rs752113748	1279	T>P		No	ClinGen ExAC gnomAD
rs757558783 CA2909003	1280	C>Y		No	ClinGen ExAC gnomAD
rs1415055125 CA356813653	1281	N>Y		No	ClinGen gnomAD
CA356813663 rs1436464470	1282	P>R		No	ClinGen TOPMed
rs1390182097 CA356813682	1285	N>K		No	ClinGen gnomAD
rs750588188 CA2909005	1285	N>S		No	ClinGen ExAC gnomAD
rs756372515 CA356813687	1286	P>H		No	ClinGen ExAC TOPMed gnomAD
CA2909006 rs756372515	1286	P>L		No	ClinGen ExAC TOPMed gnomAD
CA2909008 rs537212141	1287	Y>H		No	ClinGen 1000Genomes ExAC gnomAD
rs1280805319 CA356813691	1287	Y>S		No	ClinGen TOPMed
CA96655330 rs971757121	1289	I>L		No	ClinGen Ensembl
rs1224880785 CA356813716	1290	M>R		No	ClinGen TOPMed
CA96655337 rs865781144	1292	E>K		No	ClinGen Ensembl
rs919139787 CA96655342	1293	H>D		No	ClinGen TOPMed
CA96655358 rs954609099	1293	H>R		No	ClinGen Ensembl
CA2909011 rs777503185	1294	M>V		No	ClinGen ExAC gnomAD
CA2909012 rs747031885	1295	L>P		No	ClinGen ExAC gnomAD
TCGA novel	1299	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745485512 CA2909015	1300	Y>C		No	ClinGen ExAC gnomAD
CA356813799 rs1577713706	1302	V>A		No	ClinGen Ensembl
rs1283669323 CA356813803	1303	C>G		No	ClinGen gnomAD
rs769530760 CA2909016	1304	I>T		No	ClinGen ExAC
rs556426025 CA2909018	1306	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs371160449 CA2909020	1307	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1469221831 CA356813826	1307	T>P		No	ClinGen TOPMed
rs1157466045 CA356813843	1309	I>M		No	ClinGen gnomAD
CA356813867 rs1416067564	1314	R>G		No	ClinGen gnomAD
rs923658608 CA96656618	1315	F>L		No	ClinGen TOPMed
rs1328496271 CA356814348	1316	V>I		No	ClinGen gnomAD
rs1328496271 CA356814347	1316	V>L		No	ClinGen gnomAD
CA2909038 rs761263984	1317	Y>*		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1317	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356814370 rs1438616399	1318	R>G		No	ClinGen gnomAD
rs1325932428 CA356814405	1321	Q>E		No	ClinGen gnomAD
CA2909039 rs202051358	1322	G>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2909040 rs202051358	1322	G>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA2909041 rs760966304	1329	I>V		No	ClinGen ExAC TOPMed gnomAD
CA2909043 rs754044679	1331	R>K		No	ClinGen ExAC gnomAD
CA96656638 rs952386230	1332	A>G		No	ClinGen gnomAD
CA96656636 rs867726239	1332	A>S		No	ClinGen Ensembl
CA96656629 rs867726239	1332	A>T		No	ClinGen Ensembl
TCGA novel	1333	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA356814556 rs1351758401	1334	H>Q		No	ClinGen gnomAD
CA2909045 rs765197408	1336	D>E		No	ClinGen ExAC gnomAD
TCGA novel	1336	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755272519 CA2909044	1336	D>N		No	ClinGen ExAC TOPMed gnomAD
rs758429900 CA2909047	1340	P>A		No	ClinGen ExAC TOPMed gnomAD
rs758429900 CA2909048	1340	P>S		No	ClinGen ExAC TOPMed gnomAD
rs750389206 CA2909049	1342	E>G		No	ClinGen ExAC gnomAD
CA96656645 rs1015537193	1344	T>P		No	ClinGen Ensembl
rs1452499000 CA356814643	1345	K>R		No	ClinGen gnomAD
CA356814656 rs1170458573	1347	L>F		No	ClinGen gnomAD
rs200479028 CA96656648	1349	K>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1235452369 CA356814672	1349	K>N		No	ClinGen TOPMed
CA2909051 rs200479028	1349	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs748917696 CA2909053	1350	W>C		No	ClinGen ExAC gnomAD
CA2909052 rs780045645	1350	W>G		No	ClinGen ExAC TOPMed gnomAD
CA356814683 rs1394524135	1351	R>K		No	ClinGen gnomAD
CA356814691 rs1288716306	1352	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA96657162 rs976606813	1354	G>A		No	ClinGen Ensembl
CA2909054 rs768315499	1356	M>I		No	ClinGen ExAC TOPMed gnomAD
rs548274430 CA2909055	1357	N>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA2909057 rs771490282	1360	T>S		No	ClinGen ExAC gnomAD
rs773708029 CA2909059	1362	K>Q		No	ClinGen ExAC gnomAD
CA356814764 rs1290243271	1363	Y>C		No	ClinGen TOPMed gnomAD
rs367581812 CA2909061	1364	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1450979340 CA356814781	1366	Q>K		No	ClinGen gnomAD
rs759845867 CA2909063	1367	S>*		No	ClinGen ExAC gnomAD
rs765449130 CA2909064	1368	A>T		No	ClinGen ExAC TOPMed gnomAD
rs752875766 CA2909065	1370	K>N		No	ClinGen ExAC gnomAD
COSM447899 CA2909066 rs763021315	1372	G>E	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA96657178 rs549860330	1373	R>G		No	ClinGen Ensembl
CA356814824 rs1427858529	1373	R>K		No	ClinGen gnomAD
CA356814833 rs1190735648	1374	R>K		No	ClinGen gnomAD
CA2909067 rs764328031	1374	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1459609467 CA356814845	1376	M>T		No	ClinGen gnomAD
CA2909068 rs750366549	1378	G>R		No	ClinGen ExAC gnomAD
CA96657186 rs369714734	1379	P>R		No	ClinGen ESP gnomAD
CA2909069 rs756160620	1380	S>F		No	ClinGen ExAC gnomAD
CA2909070 rs780172839	1382	V>A		No	ClinGen ExAC TOPMed gnomAD
CA2909072 COSM230034 rs754747002	1385	M>I	NS [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1014782037 CA96657192	1388	A>P		No	ClinGen TOPMed
rs4145944 VAR_024371 CA2909074	1389	S>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA96657196 rs112565536	1390	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA2909076 rs777311172	1391	C>*		No	ClinGen ExAC TOPMed gnomAD
rs370150000 CA96657202	1391	C>Y		No	ClinGen ESP TOPMed gnomAD
rs35375547 CA2909077	1392	A>D		No	ClinGen ExAC TOPMed gnomAD
VAR_048395 CA96657209 rs35375547	1392	A>G		No	ClinGen UniProt ExAC TOPMed dbSNP gnomAD
CA356814944 rs35375547	1392	A>V		No	ClinGen ExAC TOPMed gnomAD
CA2909078 rs568660794	1393	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA
rs140236295 CA2909080	1394	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs140236295 CA2909079	1394	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1397	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1577718063 CA356814982	1398	L>S		No	ClinGen Ensembl
CA96657221 rs780438747	1399	S>P		No	ClinGen TOPMed gnomAD
rs1420060014 CA356815000	1401	C>S		No	ClinGen TOPMed
CA2909086 rs763134802	1402	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1417337344 CA356815014	1403	T>N	Variant assessed as Somatic; 4.63e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs533724339 CA96657228	1404	A>T		No	ClinGen 1000Genomes
rs764240036 CA96657231	1408	G>A		No	ClinGen ExAC TOPMed gnomAD
rs764240036 CA2909087	1408	G>V		No	ClinGen ExAC TOPMed gnomAD
rs1287153869 CA356815054	1409	Y>F		No	ClinGen gnomAD
CA2909089 rs762008183	1412	T>I		No	ClinGen ExAC TOPMed gnomAD
rs558941985 CA2909090	1413	K>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA356815085 rs1405014886	1414	A>S		No	ClinGen gnomAD
CA356815121 rs373941219	1419	G>*		No	ClinGen ESP TOPMed gnomAD
CA96657232 COSM318820 rs373941219	1419	G>R	lung [Cosmic]	No	ClinGen cosmic curated ESP TOPMed gnomAD
rs753727748 CA2909091	1419	G>V		No	ClinGen ExAC TOPMed
CA2909092 rs754801127	1420	P>S		No	ClinGen ExAC gnomAD
CA356815125 rs754801127	1420	P>T		No	ClinGen ExAC gnomAD
CA2909093 rs765003197	1423	G>D		No	ClinGen ExAC TOPMed gnomAD
rs924128502 CA96657236	1423	G>R		No	ClinGen TOPMed
rs765003197 CA356815145	1423	G>V		No	ClinGen ExAC TOPMed gnomAD
rs145210912 CA2909094	1427	S>W		No	ClinGen ESP ExAC TOPMed gnomAD

No associated diseases with Q9P241

3 regional properties for Q9P241

Type	Name	Position	InterPro Accession
domain	Protein kinase domain	46 - 300	IPR000719
active_site	Serine/threonine-protein kinase, active site	160 - 172	IPR008271
binding_site	Protein kinase, ATP binding site	52 - 75	IPR017441

Functions

		Description
EC Number	7.6.2.1	Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization	Cell membrane ; Multi-pass membrane protein Endoplasmic reticulum membrane ; Multi-pass membrane protein	Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

7 GO annotations of cellular component

Name	Definition
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
phospholipid-translocating ATPase complex	A protein complex that functions as a phospholipid-translocating P-Type ATPase.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

5 GO annotations of molecular function

Name	Definition
ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATPase-coupled intramembrane lipid transporter activity	Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.
glycosylceramide flippase activity	Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.
magnesium ion binding	Binding to a magnesium (Mg) ion.

3 GO annotations of biological process

Name	Definition
cation transport	The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ion transmembrane transport	A process in which an ion is transported across a membrane.
phospholipid translocation	The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.

11 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
O43520	ATP8B1	Phospholipid-transporting ATPase IC	Homo sapiens (Human)	EV
P98198	ATP8B2	Phospholipid-transporting ATPase ID	Homo sapiens (Human)	PR
Q8TF62	ATP8B4	Probable phospholipid-transporting ATPase IM	Homo sapiens (Human)	PR
Q9Y2Q0	ATP8A1	Phospholipid-transporting ATPase IA	Homo sapiens (Human)	PR
O43861	ATP9B	Probable phospholipid-transporting ATPase IIB	Homo sapiens (Human)	PR
Q148W0	Atp8b1	Phospholipid-transporting ATPase IC	Mus musculus (Mouse)	SS
P70704	Atp8a1	Phospholipid-transporting ATPase IA	Mus musculus (Mouse)	PR
P98199	Atp8b2	Phospholipid-transporting ATPase ID	Mus musculus (Mouse)	PR
D4AA47	Atp8b1	Phospholipid-transporting ATPase IC	Rattus norvegicus (Rat)	SS
Q9U280	tat-1	Phospholipid-transporting ATPase tat-1	Caenorhabditis elegans	PR
Q5BL50	atp8b1	Phospholipid-transporting ATPase IC	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	SS

10	20	30	40	50	60
MTEALQWARY	HWRRLIRGAT	RDDDSGPYNY	SSLLACGRKS	SQTPKLSGRH	RIVVPHIQPF
70	80	90	100	110	120
KDEYEKFSGA	YVNNRIRTTK	YTLLNFVPRN	LFEQFHRAAN	LYFLFLVVLN	WVPLVEAFQK
130	140	150	160	170	180
EITMLPLVVV	LTIIAIKDGL	EDYRKYKIDK	QINNLITKVY	SRKEKKYIDR	CWKDVTVGDF
190	200	210	220	230	240
IRLSCNEVIP	ADMVLLFSTD	PDGICHIETS	GLDGESNLKQ	RQVVRGYAEQ	DSEVDPEKFS
250	260	270	280	290	300
SRIECESPNN	DLSRFRGFLE	HSNKERVGLS	KENLLLRGCT	IRNTEAVVGI	VVYAGHETKA
310	320	330	340	350	360
MLNNSGPRYK	RSKLERRANT	DVLWCVMLLV	IMCLTGAVGH	GIWLSRYEKM	HFFNVPEPDG
370	380	390	400	410	420
HIISPLLAGF	YMFWTMIILL	QVLIPISLYV	SIEIVKLGQI	YFIQSDVDFY	NEKMDSIVQC
430	440	450	460	470	480
RALNIAEDLG	QIQYLFSDKT	GTLTENKMVF	RRCSVAGFDY	CHEENARRLE	SYQEAVSEDE
490	500	510	520	530	540
DFIDTVSGSL	SNMAKPRAPS	CRTVHNGPLG	NKPSNHLAGS	SFTLGSGEGA	SEVPHSRQAA
550	560	570	580	590	600
FSSPIETDVV	PDTRLLDKFS	QITPRLFMPL	DETIQNPPME	TLYIIDFFIA	LAICNTVVVS
610	620	630	640	650	660
APNQPRQKIR	HPSLGGLPIK	SLEEIKSLFQ	RWSVRRSSSP	SLNSGKEPSS	GVPNAFVSRL
670	680	690	700	710	720
PLFSRMKPAS	PVEEEVSQVC	ESPQCSSSSA	CCTETEKQHG	DAGLLNGKAE	SLPGQPLACN
730	740	750	760	770	780
LCYEAESPDE	AALVYAARAY	QCTLRSRTPE	QVMVDFAALG	PLTFQLLHIL	PFDSVRKRMS
790	800	810	820	830	840
VVVRHPLSNQ	VVVYTKGADS	VIMELLSVAS	PDGASLEKQQ	MIVREKTQKH	LDDYAKQGLR
850	860	870	880	890	900
TLCIAKKVMS	DTEYAEWLRN	HFLAETSIDN	REELLLESAM	RLENKLTLLG	ATGIEDRLQE
910	920	930	940	950	960
GVPESIEALH	KAGIKIWMLT	GDKQETAVNI	AYACKLLEPD	DKLFILNTQS	KDACGMLMST
970	980	990	1000	1010	1020
ILKELQKKTQ	ALPEQVSLSE	DLLQPPVPRD	SGLRAGLIIT	GKTLEFALQE	SLQKQFLELT
1030	1040	1050	1060	1070	1080
SWCQAVVCCR	ATPLQKSEVV	KLVRSHLQVM	TLAIGDGAND	VSMIQVADIG	IGVSGQEGMQ
1090	1100	1110	1120	1130	1140
AVMASDFAVS	QFKHLSKLLL	VHGHWCYTRL	SNMILYFFYK	NVAYVNLLFW	YQFFCGFSGT
1150	1160	1170	1180	1190	1200
SMTDYWVLIF	FNLLFTSAPP	VIYGVLEKDV	SAETLMQLPE	LYRSGQKSEA	YLPHTFWITL
1210	1220	1230	1240	1250	1260
LDAFYQSLVC	FFVPYFTYQG	SDTDIFAFGN	PLNTAALFIV	LLHLVIESKS	LTWIHLLVII
1270	1280	1290	1300	1310	1320
GSILSYFLFA	IVFGAMCVTC	NPPSNPYWIM	QEHMLDPVFY	LVCILTTSIA	LLPRFVYRVL
1330	1340	1350	1360	1370	1380
QGSLFPSPIL	RAKHFDRLTP	EERTKALKKW	RGAGKMNQVT	SKYANQSAGK	SGRRPMPGPS
1390	1400	1410	1420
AVFAMKSASS	CAIEQGNLSL	CETALDQGYS	ETKAFEMAGP	SKGKES