Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9M2J5

Entry ID Method Resolution Chain Position Source
AF-Q9M2J5-F1 Predicted AlphaFoldDB

45 variants for Q9M2J5

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06337340 5 V>I No 1000Genomes
ENSVATH02520859 14 Q>E No 1000Genomes
ENSVATH02520858 19 S>F No 1000Genomes
ENSVATH14450460 26 S>P No 1000Genomes
tmp_3_21563986_G_GATTA 28 Q>* No 1000Genomes
ENSVATH02520853 36 W>* No 1000Genomes
tmp_3_21563853_C_T 43 E>K No 1000Genomes
tmp_3_21563832_C_T 50 D>N No 1000Genomes
ENSVATH02520851 59 A>P No 1000Genomes
ENSVATH06337339 62 R>K No 1000Genomes
tmp_3_21563745_C_A 79 V>F No 1000Genomes
tmp_3_21563727_T_G 85 K>Q No 1000Genomes
tmp_3_21563712_T_C 90 N>D No 1000Genomes
ENSVATH06337331 100 I>S No 1000Genomes
ENSVATH06337330 112 T>S No 1000Genomes
ENSVATH06337329 118 D>N No 1000Genomes
tmp_3_21563348_C_T 126 E>K No 1000Genomes
ENSVATH06337328 129 I>V No 1000Genomes
ENSVATH06337327 132 E>D No 1000Genomes
ENSVATH06337325 140 G>D No 1000Genomes
ENSVATH06337325 140 G>V No 1000Genomes
ENSVATH02520840 146 E>G No 1000Genomes
ENSVATH12817586 162 K>E No 1000Genomes
tmp_3_21563236_A_T 163 V>E No 1000Genomes
ENSVATH06337323 179 P>A No 1000Genomes
ENSVATH06337322 183 E>K No 1000Genomes
ENSVATH12817585 189 G>A No 1000Genomes
ENSVATH14450457 198 D>E No 1000Genomes
tmp_3_21562983_G_A 219 P>S No 1000Genomes
ENSVATH02520837 224 A>S No 1000Genomes
ENSVATH00425777 227 N>T No 1000Genomes
tmp_3_21562951_C_A 229 L>F No 1000Genomes
ENSVATH06337319 236 L>F No 1000Genomes
ENSVATH02520836 239 P>L No 1000Genomes
tmp_3_21562902_C_T 246 E>K No 1000Genomes
ENSVATH06337318 256 T>A No 1000Genomes
ENSVATH06337317 263 F>S No 1000Genomes
tmp_3_21562824_G_C 272 L>V No 1000Genomes
ENSVATH12817544 284 T>S No 1000Genomes
tmp_3_21562784_C_A 285 G>V No 1000Genomes
ENSVATH02520835 298 E>D No 1000Genomes
ENSVATH14450456 305 D>E No 1000Genomes
ENSVATH14450455 307 E>K No 1000Genomes
ENSVATH06337316 312 K>E No 1000Genomes
tmp_3_21562674_C_T 322 A>T No 1000Genomes

No associated diseases with Q9M2J5

6 regional properties for Q9M2J5

Type Name Position InterPro Accession
domain 5'-3' exonuclease 29 - 299 IPR002421
domain XPG, N-terminal 1 - 108 IPR006085
domain XPG-I domain 147 - 234 IPR006086
conserved_site Helix-hairpin-helix motif, class 2 221 - 254 IPR008918
conserved_site XPG conserved site 80 - 94 IPR019974-1
conserved_site XPG conserved site 150 - 164 IPR019974-2

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6IQ16 SPOPL Speckle-type POZ protein-like Homo sapiens (Human) PR
Q6YCH2 Tdpoz4 TD and POZ domain-containing protein 4 Mus musculus (Mouse) PR
Q2M2N2 Spopl Speckle-type POZ protein-like Mus musculus (Mouse) PR
P34371 bath-42 BTB and MATH domain-containing protein 42 Caenorhabditis elegans PR
F4IN32 At2g42460 MATH domain and coiled-coil domain-containing protein At2g42460 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A0 At3g44790 MATH domain and coiled-coil domain-containing protein At3g44790 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A1 At3g44800 MATH domain and coiled-coil domain-containing protein At3g44800 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG7 At2g42480 MATH domain and coiled-coil domain-containing protein At2g42480 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSD2 At3g27040 MATH domain and coiled-coil domain-containing protein At3g27040 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2I2 At3g58340 MATH domain and coiled-coil domain-containing protein At3g58340 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J0 At3g58260 MATH domain and coiled-coil domain-containing protein At3g58260 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUA7 At2g01790 MATH domain and coiled-coil domain-containing protein At2g01790 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG4 At2g42465 MATH domain and coiled-coil domain-containing protein At2g42465 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SHT3 At2g05410 MATH domain and coiled-coil domain-containing protein At2g05410 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4P8 At3g58220 MATH domain and coiled-coil domain-containing protein At3g58220 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGNLVDNKFT WVIQNFSSSQ SRVVPSNQFV IGGCKWRLLV YPEGFNKSGD HLSLFLEVAD
70 80 90 100 110 120
PRSLPPGWSR HARYLLTIVN QHSDKISKRN EATKWFNQKI PGWGLSAMIP LTKLHAKDGG
130 140 150 160 170 180
FLVNDELKIV AEVNVLEVIG KLDVPEESEE ETQVTQPMKK VKVDYDHVES NDLMINETPP
190 200 210 220 230 240
VSELMDVNGF QVLPSQVDFV KRIFEKHPDI AKDFRPKNPH LRKACMNFLL SLMETLCQPP
250 260 270 280 290 300
QKLSNEDLVE ADNALTYVKV SGFKVDWLEK KLEEVKKKKE EEQTGEARIQ ELEEELKEFK
310 320
QKCLDREAML EKEKAKVLTA RAPLTLDDVI