Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LZJ6

Entry ID Method Resolution Chain Position Source
AF-Q9LZJ6-F1 Predicted AlphaFoldDB

29 variants for Q9LZJ6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH12889078 6 D>H No 1000Genomes
tmp_3_23186572_A_T 11 L>I No 1000Genomes
ENSVATH06361758 15 M>I No 1000Genomes
tmp_3_23186542_G_C 21 R>G No 1000Genomes
ENSVATH06361756 40 V>I No 1000Genomes
tmp_3_23186398_G_T 69 L>I No 1000Genomes
ENSVATH12889054 74 A>V No 1000Genomes
tmp_3_23186372_G_C 77 D>E No 1000Genomes
ENSVATH02538041 80 Q>H No 1000Genomes
ENSVATH12889053 91 T>K No 1000Genomes
ENSVATH12889052 92 V>M No 1000Genomes
ENSVATH06361755 94 E>D No 1000Genomes
ENSVATH06361754 109 P>A No 1000Genomes
ENSVATH12889050 119 E>K No 1000Genomes
ENSVATH06361751 122 E>D No 1000Genomes
ENSVATH12889049 125 E>K No 1000Genomes
ENSVATH00432731 171 A>T No 1000Genomes
ENSVATH06361748 194 S>F No 1000Genomes
ENSVATH02538039 198 T>K No 1000Genomes
tmp_3_23185954_C_T 217 E>K No 1000Genomes
tmp_3_23185935_C_T 223 G>D No 1000Genomes
tmp_3_23185913_C_G 230 R>S No 1000Genomes
ENSVATH02538037 233 Q>E No 1000Genomes
ENSVATH00432729 236 N>S No 1000Genomes
ENSVATH06361747 241 A>V No 1000Genomes
ENSVATH06361746 245 S>P No 1000Genomes
ENSVATH02538035 247 R>H No 1000Genomes
ENSVATH02538036 247 R>S No 1000Genomes
tmp_3_23185858_C_G 249 A>P No 1000Genomes

No associated diseases with Q9LZJ6

1 regional properties for Q9LZJ6

Type Name Position InterPro Accession
domain Zinc finger, RING-type 112 - 155 IPR001841

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
ubiquitin protein ligase binding Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.

2 GO annotations of biological process

Name Definition
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
protein-containing complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VE61 CG7694 E3 ubiquitin-protein ligase RNF181 homolog Drosophila melanogaster (Fruit fly) PR
O00237 RNF103 E3 ubiquitin-protein ligase RNF103 Homo sapiens (Human) PR
Q86Y13 DZIP3 E3 ubiquitin-protein ligase DZIP3 Homo sapiens (Human) PR
Q9Y3E7 CHMP3 Charged multivesicular body protein 3 Homo sapiens (Human) EV
Q9R1W3 Rnf103 E3 ubiquitin-protein ligase RNF103 Mus musculus (Mouse) PR
Q9EPZ8 Rnf103 E3 ubiquitin-protein ligase RNF103 Rattus norvegicus (Rat) PR
Q9ZV51 ATL56 RING-H2 finger protein ATL56 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SKK8 ATL22 RING-H2 finger protein ATL22 Arabidopsis thaliana (Mouse-ear cress) PR
P0CH02 ATL21B Putative RING-H2 finger protein ATL21B Arabidopsis thaliana (Mouse-ear cress) PR
P0CH01 ATL21A Putative RING-H2 finger protein ATL21A Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXF8 SGR9 E3 ubiquitin-protein ligase SGR9, amyloplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI09 XERICO Probable E3 ubiquitin-protein ligase XERICO Arabidopsis thaliana (Mouse-ear cress) PR
O22255 ATL64 RING-H2 finger protein ATL64 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYT9 SIS3 E3 ubiquitin-protein ligase SIS3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LGA5 ATL31 E3 ubiquitin-protein ligase ATL31 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RXX9 ATL6 E3 ubiquitin-protein ligase ATL6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUZ9 ATL63 RING-H2 finger protein ATL63 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGNLFDSSKT LWGNMNHGSS RYSLNGKIML ASVIILFVAV ILILCFHSYA RWLFRRQNRR
70 80 90 100 110 120
IRRRISAHLR SLAAARDPTQ SSSSLSPLDP TVLEKIPIFV YSVKTHESPL EECSVCLSEF
130 140 150 160 170 180
EEDDEGRVLP KCGHVFHVDC IDTWFRSRSS CPLCRAPVQP AQPVTEPEPV AAVFPSVKPI
190 200 210 220 230 240
EDTEAGSSSS SDESESSTPS SSSGSPVRFP MEACEREPID LVGIIVEIPR EFQDSNSDLP
250
ADNGSNRRAS LKRLWII