Q9LYN6

PR
Gene name
At3g56050 (F18O21.10)
Protein name
Probable inactive receptor-like protein kinase At3g56050
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G56050
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

51-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LYN6

Entry ID Method Resolution Chain Position Source
AF-Q9LYN6-F1 Predicted AlphaFoldDB

36 variants for Q9LYN6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06324609 2 S>T No 1000Genomes
ENSVATH06324608 17 L>F No 1000Genomes
ENSVATH14441934 30 Y>F No 1000Genomes
ENSVATH02512739 30 Y>H No 1000Genomes
tmp_3_20800508_T_A 37 D>V No 1000Genomes
ENSVATH06324605 52 D>A No 1000Genomes
tmp_3_20800455_C_T 55 D>N No 1000Genomes
ENSVATH06324595 81 D>G No 1000Genomes
tmp_3_20799874_G_T 83 P>T No 1000Genomes
ENSVATH06324594 94 V>I No 1000Genomes
tmp_3_20799834_G_A 96 T>M No 1000Genomes
tmp_3_20799831_C_T 97 R>K No 1000Genomes
ENSVATH02512723 99 D>N No 1000Genomes
tmp_3_20799774_T_A 116 Q>L No 1000Genomes
tmp_3_20799768_A_C 118 V>G No 1000Genomes
tmp_3_20799681_A_G 147 I>T No 1000Genomes
tmp_3_20799682_T_C 147 I>V No 1000Genomes
ENSVATH06324590 148 V>L No 1000Genomes
ENSVATH06324590 148 V>M No 1000Genomes
ENSVATH00422064 152 I>V No 1000Genomes
ENSVATH12787782 161 L>S No 1000Genomes
tmp_3_20799614_T_G 169 K>N No 1000Genomes
ENSVATH14441931 172 A>V No 1000Genomes
tmp_3_20799252_A_C 248 N>K No 1000Genomes
ENSVATH12787779 250 I>L No 1000Genomes
tmp_3_20799137_T_A 259 E>D No 1000Genomes
tmp_3_20799028_C_T 296 V>I No 1000Genomes
tmp_3_20798886_C_G 312 M>I No 1000Genomes
ENSVATH00422059 313 R>Q No 1000Genomes
tmp_3_20798819_C_G 335 V>L No 1000Genomes
tmp_3_20798767_A_G 352 V>A No 1000Genomes
ENSVATH02512700 400 M>I No 1000Genomes
tmp_3_20798602_G_A 407 S>L No 1000Genomes
ENSVATH02512697 409 Q>K No 1000Genomes
ENSVATH12787764 412 D>E No 1000Genomes
tmp_3_20798464_A_G 453 I>T No 1000Genomes

No associated diseases with Q9LYN6

4 regional properties for Q9LYN6

Type Name Position InterPro Accession
domain Protein kinase domain 46 - 300 IPR000719
domain AGC-kinase, C-terminal 301 - 355 IPR000961
active_site Serine/threonine-protein kinase, active site 165 - 177 IPR008271
binding_site Protein kinase, ATP binding site 52 - 75 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

25 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9Y616 IRAK3 Interleukin-1 receptor-associated kinase 3 Homo sapiens (Human) PR
P53667 LIMK1 LIM domain kinase 1 Homo sapiens (Human) PR
P53671 LIMK2 LIM domain kinase 2 Homo sapiens (Human) PR
Q8K4B2 Irak3 Interleukin-1 receptor-associated kinase 3 Mus musculus (Mouse) PR
Q8CFA1 Irak2 Interleukin-1 receptor-associated kinase-like 2 Mus musculus (Mouse) PR
O54785 Limk2 LIM domain kinase 2 Mus musculus (Mouse) PR
Q4QQS0 Irak2 Interleukin-1 receptor-associated kinase-like 2 Rattus norvegicus (Rat) PR
Q9ASQ5 CRCK3 Calmodulin-binding receptor-like cytoplasmic kinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LPS5 SERK5 Somatic embryogenesis receptor kinase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RWW0 ALE2 Receptor-like serine/threonine-protein kinase ALE2 Arabidopsis thaliana (Mouse-ear cress) PR
P93050 BSH Probable LRR receptor-like serine/threonine-protein kinase RKF3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRP3 At3g17420 Probable receptor-like protein kinase At3g17420 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSV3 WAKL16 Putative wall-associated receptor kinase-like 16 Arabidopsis thaliana (Mouse-ear cress) PR
Q9STF0 LECRKS3 Receptor like protein kinase S.3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCZ4 FER Receptor-like protein kinase FERONIA Arabidopsis thaliana (Mouse-ear cress) PR
Q9M342 WAKL15 Wall-associated receptor kinase-like 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZJ9 CRCK2 Calmodulin-binding receptor-like cytoplasmic kinase 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q0WNY5 WAKL18 Wall-associated receptor kinase-like 18 Arabidopsis thaliana (Mouse-ear cress) PR
P43293 PBL11 Probable serine/threonine-protein kinase PBL11 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C25 At5g20050 Probable receptor-like protein kinase At5g20050 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FLW0 At5g24010 Probable receptor-like protein kinase At5g24010 Arabidopsis thaliana (Mouse-ear cress) PR
Q3E8W4 ANX2 Receptor-like protein kinase ANXUR2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTC0 PBL19 Probable serine/threonine-protein kinase PBL19 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIL7 CRCK1 Calmodulin-binding receptor-like cytoplasmic kinase 1 Arabidopsis thaliana (Mouse-ear cress) PR
C0LGQ4 MDIS2 Protein MALE DISCOVERER 2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSNNWKSVRL RLQNRTLVFL LVILSFGSCY SLKSQGDGFL ESVTKDLWSD IDAEDLRAVG
70 80 90 100 110 120
FHRKLLGRFR NPYTHLNAFR DRPVARATPP SSSVSTRPDA KRSSTLPPPQ KSPPAQHVSA
130 140 150 160 170 180
PPPFVHHVTL PSLTSSSKTS SNSTIPIVAG CIAGAVFILL LATGVFFFKS KAGKSVNPWR
190 200 210 220 230 240
TGLSGQLQKV FITGVPKLKR SEIEAACEDF SNVIGSCPIG TLFKGTLSSG VEIAVASVAT
250 260 270 280 290 300
ASAKEWTNNI EMQFRKKIEM LSKINHKNFV NLLGYCEEEE PFTRILVFEY ASNGTVFEHL
310 320 330 340 350 360
HYKESEHLDW VMRLRIAMGI AYCLDHMHGL KPPIVHSNLL SSSVQLTEDY AVKIADFNFG
370 380 390 400 410 420
YLKGPSETES STNALIDTNI SETTQEDNVH SFGLLLFELM TGKLPESVQK GDSIDTGLAV
430 440 450 460 470 480
FLRGKTLREM VDPTIESFDE KIENIGEVIK SCIRADAKQR PIMKEVTGRL REITGLSPDD
490
TIPKLSPLWW AELEVLSTA