Q9LUZ9
PR
Gene name |
ATL63 (At5g58580, MZN1.3) |
Protein name |
RING-H2 finger protein ATL63 |
Names |
Protein ARABIDOPSIS TOXICOS EN LEVADURA 63, Protein ATL63, RING-type E3 ubiquitin transferase ATL63 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G58580 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LUZ9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LUZ9-F1 | Predicted | AlphaFoldDB |
34 variants for Q9LUZ9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00741127 | 6 | G>D | No | 1000Genomes | |
| tmp_5_23677786_G_T | 16 | S>* | No | 1000Genomes | |
| tmp_5_23677787_A_T,G | 16 | S>P | No | 1000Genomes | |
| tmp_5_23677787_A_T,G | 16 | S>T | No | 1000Genomes | |
| ENSVATH12844210 | 20 | K>N | No | 1000Genomes | |
| ENSVATH07445966 | 22 | L>F | No | 1000Genomes | |
| ENSVATH03448699 | 26 | N>K | No | 1000Genomes | |
| ENSVATH14639553 | 57 | P>S | No | 1000Genomes | |
| tmp_5_23677643_C_T | 64 | A>T | No | 1000Genomes | |
| ENSVATH00741126 | 77 | R>I | No | 1000Genomes | |
| ENSVATH07445963 | 80 | V>L | No | 1000Genomes | |
| ENSVATH03448697 | 89 | L>F | No | 1000Genomes | |
| ENSVATH03448695 | 95 | D>N | No | 1000Genomes | |
| ENSVATH14639552 | 97 | G>R | No | 1000Genomes | |
| ENSVATH03448694 | 98 | V>I | No | 1000Genomes | |
| ENSVATH03448694 | 98 | V>L | No | 1000Genomes | |
| ENSVATH07445962 | 100 | S>F | No | 1000Genomes | |
| tmp_5_23677513_C_G | 107 | R>T | No | 1000Genomes | |
| ENSVATH03448693 | 128 | N>D | No | 1000Genomes | |
| tmp_5_23677448_C_T | 129 | E>K | No | 1000Genomes | |
| ENSVATH07445961 | 132 | E>K | No | 1000Genomes | |
| ENSVATH03448692 | 133 | D>E | No | 1000Genomes | |
| tmp_5_23677390_C_G | 148 | G>A | No | 1000Genomes | |
| ENSVATH14639551 | 184 | L>V | No | 1000Genomes | |
| ENSVATH07445959 | 189 | D>E | No | 1000Genomes | |
| ENSVATH03448686 | 193 | L>I | No | 1000Genomes | |
| ENSVATH03448685 | 195 | L>P | No | 1000Genomes | |
| ENSVATH03448684 | 216 | N>D | No | 1000Genomes | |
| ENSVATH03448682 | 237 | L>F | No | 1000Genomes | |
| ENSVATH03448681 | 243 | D>E | No | 1000Genomes | |
| ENSVATH03448679 | 261 | D>G | No | 1000Genomes | |
| ENSVATH03448678 | 264 | T>S | No | 1000Genomes | |
| ENSVATH00741122 | 295 | R>G | No | 1000Genomes | |
| tmp_5_23676929_C_T | 302 | A>T | No | 1000Genomes |
No associated diseases with Q9LUZ9
1 regional properties for Q9LUZ9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, RING-type | 137 - 180 | IPR001841 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| early endosome | A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi-associated vesicle | Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| ubiquitin protein ligase binding | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to osmotic stress | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
| regulation of endocytosis | Any process that modulates the frequency, rate or extent of endocytosis. |
| regulation of reactive oxygen species biosynthetic process | Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. |
| regulation of response to salt stress | Any process that modulates the frequency, rate or extent of response to salt stress. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEEDGGSMS | VKSSLSSFLK | ILSSYNSNVL | LAALVFLLLV | VLFVLLLHFY | ARFFWSPSHQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DFSAAARHRR | RRRRNRRRTV | TTTRIIPSLP | LGGFDDGVSS | PAATATRDDK | GLDSSVISSI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PLFVYEENEE | EEDEEEECVI | CLGLWEAGDF | GRKLRNCGHG | FHVECIDMWL | SSHSTCPLCR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPVLAAVSDE | ENLKLAVNAV | EEEAEVRLQM | SPAGENESNV | SGDRRVSLSL | SVMEDDLKTG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DDDGEEEVRI | EVFDDDEEIN | DGGTRSDRRR | SMSMTSSASS | SLMRMLSSSS | SRSERNKVFP |
| TARQDSSK |