Q9LRR4
PR
Gene name |
RPPL1 (At3g14470, MOA2.9) |
Protein name |
Putative disease resistance RPP13-like protein 1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G14470 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LRR4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LRR4-F1 | Predicted | AlphaFoldDB |
124 variants for Q9LRR4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_4857947_G_T | 3 | G>V | No | 1000Genomes | |
| tmp_3_4857973_T_A | 12 | F>I | No | 1000Genomes | |
| ENSVATH13918024 | 12 | F>S | No | 1000Genomes | |
| ENSVATH00323179 | 26 | R>K | No | 1000Genomes | |
| ENSVATH02144425 | 32 | R>Q | No | 1000Genomes | |
| ENSVATH02144426 | 37 | N>S | No | 1000Genomes | |
| ENSVATH00323180 | 38 | L>F | No | 1000Genomes | |
| ENSVATH05830319 | 40 | E>Q | No | 1000Genomes | |
| tmp_3_4858146_G_A | 69 | W>* | No | 1000Genomes | |
| tmp_3_4858147_G_A | 70 | V>I | No | 1000Genomes | |
| tmp_3_4858155_G_T | 72 | E>D | No | 1000Genomes | |
| ENSVATH00323183 | 91 | A>S | No | 1000Genomes | |
| ENSVATH02144427 | 96 | I>V | No | 1000Genomes | |
| ENSVATH05830320 | 107 | R>T | No | 1000Genomes | |
| ENSVATH10675691 | 125 | H>Y | No | 1000Genomes | |
| tmp_3_4858372_A_T | 145 | N>Y | No | 1000Genomes | |
| ENSVATH13918055 | 151 | E>V | No | 1000Genomes | |
| tmp_3_4858402_A_T | 155 | M>L | No | 1000Genomes | |
| tmp_3_4858405_A_T | 156 | I>L | No | 1000Genomes | |
| ENSVATH05830322 | 159 | Q>K | No | 1000Genomes | |
| tmp_3_4858442_A_G | 168 | D>G | No | 1000Genomes | |
| tmp_3_4858499_T_C | 187 | I>T | No | 1000Genomes | |
| ENSVATH10675692 | 193 | D>G | No | 1000Genomes | |
| ENSVATH05830323 | 194 | N>K | No | 1000Genomes | |
| tmp_3_4858526_T_A | 196 | I>N | No | 1000Genomes | |
| ENSVATH05830324 | 212 | L>H | No | 1000Genomes | |
| tmp_3_4858600_C_A | 221 | H>N | No | 1000Genomes | |
| ENSVATH00323186 | 225 | Y>H | No | 1000Genomes | |
| ENSVATH00323186 | 225 | Y>N | No | 1000Genomes | |
| tmp_3_4858717_G_C | 260 | D>H | No | 1000Genomes | |
| ENSVATH05830327 | 274 | G>E | No | 1000Genomes | |
| ENSVATH02144428 | 275 | T>A | No | 1000Genomes | |
| ENSVATH00323188 | 276 | G>S | No | 1000Genomes | |
| tmp_3_4858808_A_T | 290 | N>I | No | 1000Genomes | |
| ENSVATH05830332 | 293 | D>G | No | 1000Genomes | |
| ENSVATH13918056 | 296 | L>F | No | 1000Genomes | |
| tmp_3_4858841_T_G | 301 | F>C | No | 1000Genomes | |
| ENSVATH05830333 | 306 | Q>P | No | 1000Genomes | |
| tmp_3_4858890_A_C | 317 | Q>H | No | 1000Genomes | |
| tmp_3_4858889_A_G | 317 | Q>R | No | 1000Genomes | |
| ENSVATH02144430 | 325 | A>S | No | 1000Genomes | |
| ENSVATH02144433 | 328 | V>A | No | 1000Genomes | |
| ENSVATH02144432 | 328 | V>L | No | 1000Genomes | |
| tmp_3_4858927_A_G | 330 | N>D | No | 1000Genomes | |
| ENSVATH02144434 | 350 | N>S | No | 1000Genomes | |
| ENSVATH05830336 | 350 | N>Y | No | 1000Genomes | |
| ENSVATH02144435 | 352 | E>D | No | 1000Genomes | |
| tmp_3_4858993_G_A | 352 | E>K | No | 1000Genomes | |
| ENSVATH05830337 | 353 | P>Q | No | 1000Genomes | |
| ENSVATH02144436 | 355 | L>I | No | 1000Genomes | |
| ENSVATH02144437 | 356 | N>D | No | 1000Genomes | |
| tmp_3_4859009_G_A | 357 | R>Q | No | 1000Genomes | |
| tmp_3_4859101_G_A | 388 | G>R | No | 1000Genomes | |
| ENSVATH02144440 | 391 | I>V | No | 1000Genomes | |
| tmp_3_4859257_C_A | 440 | H>N | No | 1000Genomes | |
| ENSVATH05830341 | 442 | F>I | No | 1000Genomes | |
| ENSVATH02144443 | 445 | D>E | No | 1000Genomes | |
| ENSVATH02144444 | 458 | Q>E | No | 1000Genomes | |
| ENSVATH02144447 | 465 | N>S | No | 1000Genomes | |
| ENSVATH02144448 | 471 | N>D | No | 1000Genomes | |
| ENSVATH02144449 | 472 | E>A | No | 1000Genomes | |
| ENSVATH02144453 | 483 | L>F | No | 1000Genomes | |
| ENSVATH13918057 | 494 | D>E | No | 1000Genomes | |
| ENSVATH02144457 | 500 | A>S | No | 1000Genomes | |
| tmp_3_4859450_C_T | 504 | S>L | No | 1000Genomes | |
| tmp_3_4859494_G_C | 519 | V>L | No | 1000Genomes | |
| ENSVATH00323196 | 521 | E>K | No | 1000Genomes | |
| tmp_3_4859609_C_G | 557 | T>R | No | 1000Genomes | |
| ENSVATH00323200 | 567 | Q>K | No | 1000Genomes | |
| tmp_3_4859666_C_T | 576 | T>M | No | 1000Genomes | |
| ENSVATH00323204 | 589 | K>R | No | 1000Genomes | |
| ENSVATH00323205 | 599 | K>R | No | 1000Genomes | |
| tmp_3_4859750_C_T | 604 | A>V | No | 1000Genomes | |
| tmp_3_4859770_C_T | 611 | R>C | No | 1000Genomes | |
| ENSVATH02144460 | 623 | Y>F | No | 1000Genomes | |
| ENSVATH02144460 | 623 | Y>S | No | 1000Genomes | |
| ENSVATH10675795 | 635 | C>Y | No | 1000Genomes | |
| tmp_3_4859846_C_T | 636 | S>L | No | 1000Genomes | |
| ENSVATH02144461 | 666 | R>Q | No | 1000Genomes | |
| ENSVATH00323210 | 666 | R>W | No | 1000Genomes | |
| ENSVATH02144462 | 670 | R>K | No | 1000Genomes | |
| ENSVATH00323212 | 683 | S>N | No | 1000Genomes | |
| ENSVATH10675797 | 685 | S>G | No | 1000Genomes | |
| ENSVATH02144464 | 689 | R>K | No | 1000Genomes | |
| ENSVATH02144466 | 691 | S>C | No | 1000Genomes | |
| ENSVATH00323213 | 695 | G>E | No | 1000Genomes | |
| ENSVATH05830345 | 702 | K>E | No | 1000Genomes | |
| ENSVATH05830347 | 711 | V>A | No | 1000Genomes | |
| ENSVATH05830348 | 715 | A>T | No | 1000Genomes | |
| ENSVATH00323214 | 719 | E>G | No | 1000Genomes | |
| tmp_3_4860098_C_T | 720 | A>V | No | 1000Genomes | |
| ENSVATH13918059 | 723 | N>K | No | 1000Genomes | |
| tmp_3_4860122_T_G | 728 | L>R | No | 1000Genomes | |
| ENSVATH02144467 | 729 | R>K | No | 1000Genomes | |
| ENSVATH02144468 | 744 | N>S | No | 1000Genomes | |
| tmp_3_4860235_C_T | 766 | H>Y | No | 1000Genomes | |
| tmp_3_4860272_G_A | 778 | R>K | No | 1000Genomes | |
| ENSVATH02144470 | 802 | Y>F | No | 1000Genomes | |
| tmp_3_4860347_G_T | 803 | C>F | No | 1000Genomes | |
| ENSVATH05830351 | 811 | Q>K | No | 1000Genomes | |
| tmp_3_4860388_G_A | 817 | E>K | No | 1000Genomes | |
| tmp_3_4860422_G_C | 828 | S>T | No | 1000Genomes | |
| tmp_3_4860431_G_A | 831 | R>H | No | 1000Genomes | |
| ENSVATH10675799 | 843 | Q>H | No | 1000Genomes | |
| tmp_3_4860473_A_G | 845 | Q>R | No | 1000Genomes | |
| tmp_3_4860511_A_G | 858 | N>D | No | 1000Genomes | |
| ENSVATH00323219 | 868 | V>I | No | 1000Genomes | |
| ENSVATH10675800 | 905 | H>Q | No | 1000Genomes | |
| tmp_3_4860655_A_G | 906 | I>V | No | 1000Genomes | |
| tmp_3_4860714_C_A | 925 | N>K | No | 1000Genomes | |
| tmp_3_4860722_C_A | 928 | T>K | No | 1000Genomes | |
| ENSVATH02144476 | 954 | V>I | No | 1000Genomes | |
| ENSVATH00323221 | 955 | D>H | No | 1000Genomes | |
| ENSVATH00323222 | 962 | S>T | No | 1000Genomes | |
| ENSVATH05830354 | 976 | L>R | No | 1000Genomes | |
| ENSVATH00323223 | 979 | L>M | No | 1000Genomes | |
| ENSVATH05830356 | 993 | L>P | No | 1000Genomes | |
| ENSVATH00323224 | 994 | N>S | No | 1000Genomes | |
| tmp_3_4860940_C_A | 1001 | Q>K | No | 1000Genomes | |
| ENSVATH05830357 | 1002 | V>I | No | 1000Genomes | |
| ENSVATH14850060 | 1020 | Y>F | No | 1000Genomes | |
| ENSVATH13918060 | 1030 | S>P | No | 1000Genomes | |
| ENSVATH05830359 | 1043 | R>T | No | 1000Genomes | |
| tmp_3_4861081_C_T | 1048 | R>C | No | 1000Genomes |
No associated diseases with Q9LRR4
5 regional properties for Q9LRR4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Leucine-rich repeat | 579 - 635 | IPR001611 |
| domain | NB-ARC | 176 - 398 | IPR002182 |
| repeat | Leucine-rich repeat, typical subtype | 577 - 600 | IPR003591-1 |
| repeat | Leucine-rich repeat, typical subtype | 648 - 671 | IPR003591-2 |
| domain | Rx, N-terminal | 8 - 100 | IPR041118 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP binding | Binding to ADP, adenosine 5'-diphosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| response to other organism | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. |
21 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F1MHT9 | NLRC4 | NLR family CARD domain-containing protein 4 | Bos taurus (Bovine) | SS |
| O14727 | APAF1 | Apoptotic protease-activating factor 1 | Homo sapiens (Human) | EV |
| Q9NPP4 | NLRC4 | NLR family CARD domain-containing protein 4 | Homo sapiens (Human) | SS |
| Q3UP24 | Nlrc4 | NLR family CARD domain-containing protein 4 | Mus musculus (Mouse) | EV |
| F1M649 | Nlrc4 | NLR family CARD domain-containing protein 4 | Rattus norvegicus (Rat) | SS |
| O22727 | At1g61190 | Probable disease resistance protein At1g61190 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64790 | At1g61300 | Probable disease resistance protein At1g61300 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64973 | RPS5 | Disease resistance protein RPS5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0C8S1 | RPP8L2 | Probable disease resistance RPP8-like protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P60838 | SUMM2 | Disease resistance protein SUMM2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q38834 | RPP13L4 | Disease resistance RPP13-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q39214 | RPM1 | Disease resistance protein RPM1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W3K3 | At1g58400 | Putative disease resistance protein At1g58400 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C646 | RXW24L | Probable disease resistance protein RXW24L | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FJB5 | RPP8L3 | Disease resistance RPP8-like protein 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9T048 | At4g27190 | Disease resistance protein At4g27190 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9XIF0 | At1g59780 | Putative disease resistance protein At1g59780 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4J339 | RPP1 | Probable disease resistance protein RPP1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64789 | At1g61310 | Probable disease resistance protein At1g61310 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q940K0 | UNI | Disease resistance protein UNI | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9I9H8 | apaf1 | Apoptotic protease-activating factor 1 | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTGIGEMFLA | AFLQALFQTL | VSEPFRSFFK | RRELNENLLE | RLSTALLTIT | AVLIDAEEKQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITNPVVEKWV | NELRDVVYHA | EDALDDIATE | ALRLNIGAES | SSSNRLRQLR | GRMSLGDFLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GNSEHLETRL | EKVTIRLERL | ASQRNILGLK | ELTAMIPKQR | LPTTSLVDES | EVFGRDDDKD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EIMRFLIPEN | GKDNGITVVA | IVGIGGVGKT | TLSQLLYNDQ | HVRSYFGTKV | WAHVSEEFDV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FKITKKVYES | VTSRPCEFTD | LDVLQVKLKE | RLTGTGLPFL | LVLDDLWNEN | FADWDLLRQP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FIHAAQGSQI | LVTTRSQRVA | SIMCAVHVHN | LQPLSDGDCW | SLFMKTVFGN | QEPCLNREIG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLAERIVHKC | RGLPLAVKTL | GGVLRFEGKV | IEWERVLSSR | IWDLPADKSN | LLPVLRVSYY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YLPAHLKRCF | AYCSIFPKGH | AFEKDKVVLL | WMAEGFLQQT | RSSKNLEELG | NEYFSELESR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SLLQKTKTRY | IMHDFINELA | QFASGEFSSK | FEDGCKLQVS | ERTRYLSYLR | DNYAEPMEFE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ALREVKFLRT | FLPLSLTNSS | RSCCLDQMVS | EKLLPTLTRL | RVLSLSHYKI | ARLPPDFFKN |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ISHARFLDLS | RTELEKLPKS | LCYMYNLQTL | LLSYCSSLKE | LPTDISNLIN | LRYLDLIGTK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LRQMPRRFGR | LKSLQTLTTF | FVSASDGSRI | SELGGLHDLH | GKLKIVELQR | VVDVADAAEA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NLNSKKHLRE | IDFVWRTGSS | SSENNTNPHR | TQNEAEVFEK | LRPHRHIEKL | AIERYKGRRF |
| 790 | 800 | 810 | 820 | 830 | 840 |
| PDWLSDPSFS | RIVCIRLREC | QYCTSLPSLG | QLPCLKELHI | SGMVGLQSIG | RKFYFSDQQL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RDQDQQPFRS | LETLRFDNLP | DWQEWLDVRV | TRGDLFPSLK | KLFILRCPEL | TGTLPTFLPS |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LISLHIYKCG | LLDFQPDHHE | YSYRNLQTLS | IKSSCDTLVK | FPLNHFANLD | KLEVDQCTSL |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| YSLELSNEHL | RGPNALRNLR | INDCQNLQLL | PKLNALPQNL | QVTITNCRYL | RQPMEQQPQY |
| 1030 | 1040 | 1050 | |||
| HHPQFHLPRS | NVSGSPKSHG | SHRSYDSRSS | SRYD |