Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LNK1

Entry ID Method Resolution Chain Position Source
AF-Q9LNK1-F1 Predicted AlphaFoldDB

18 variants for Q9LNK1

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_88112_T_C 12 N>D No 1000Genomes
ENSVATH04501294 16 V>A No 1000Genomes
ENSVATH07500213 20 T>K No 1000Genomes
ENSVATH00000341 54 C>Y No 1000Genomes
ENSVATH10440379 66 Q>R No 1000Genomes
tmp_1_87154_G_A 92 A>V No 1000Genomes
ENSVATH00000337 148 G>D No 1000Genomes
tmp_1_86980_C_A 150 R>L No 1000Genomes
ENSVATH01000963 158 V>L No 1000Genomes
ENSVATH13847966 161 A>S No 1000Genomes
ENSVATH13847965 162 E>K No 1000Genomes
tmp_1_86939_G_C 164 Q>E No 1000Genomes
ENSVATH04501279 165 R>Q No 1000Genomes
ENSVATH04501277 185 R>H No 1000Genomes
tmp_1_86867_C_T 188 E>K No 1000Genomes
tmp_1_86851_C_T 193 R>H No 1000Genomes
ENSVATH04501276 200 A>G No 1000Genomes
ENSVATH13847964 200 A>S No 1000Genomes

No associated diseases with Q9LNK1

1 regional properties for Q9LNK1

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 28 - 183 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Endosome membrane
  • Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor
  • During cytokinesis located to the growing margins of the cell plate
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cell plate The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.
endosome A vacuole to which materials ingested by endocytosis are delivered.
endosome membrane The lipid bilayer surrounding an endosome.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

23 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3MHP2 RAB11B Ras-related protein Rab-11B Bos taurus (Bovine) PR
Q2TA29 RAB11A Ras-related protein Rab-11A Bos taurus (Bovine) PR
Q5ZJN2 RAB11A Ras-related protein Rab-11A Gallus gallus (Chicken) PR
Q5ZHV1 RAB33B Ras-related protein Rab-33B Gallus gallus (Chicken) PR
P62490 RAB11A Ras-related protein Rab-11A Canis lupus familiaris (Dog) (Canis familiaris) PR
P62491 RAB11A Ras-related protein Rab-11A Homo sapiens (Human) PR
Q15907 RAB11B Ras-related protein Rab-11B Homo sapiens (Human) PR
Q96AX2 RAB37 Ras-related protein Rab-37 Homo sapiens (Human) PR
Q9H082 RAB33B Ras-related protein Rab-33B Homo sapiens (Human) PR
P46638 Rab11b Ras-related protein Rab-11B Mus musculus (Mouse) PR
P62492 Rab11a Ras-related protein Rab-11A Mus musculus (Mouse) PR
Q9JKM7 Rab37 Ras-related protein Rab-37 Mus musculus (Mouse) PR
O35963 Rab33b Ras-related protein Rab-33B Mus musculus (Mouse) PR
Q52NJ1 RAB11A Ras-related protein Rab-11A Sus scrofa (Pig) PR
O35509 Rab11b Ras-related protein Rab-11B Rattus norvegicus (Rat) PR
P62494 Rab11a Ras-related protein Rab-11A Rattus norvegicus (Rat) PR
Q20365 rab-33 Ras-related protein Rab-33 Caenorhabditis elegans PR
O04486 RABA2A Ras-related protein RABA2a Arabidopsis thaliana (Mouse-ear cress) PR
O49513 RABA1E Ras-related protein RABA1e Arabidopsis thaliana (Mouse-ear cress) PR
Q9FE79 RABA4C Ras-related protein RABA4c Arabidopsis thaliana (Mouse-ear cress) PR
Q9LH50 RABA4D Ras-related protein RABA4d Arabidopsis thaliana (Mouse-ear cress) PR
Q9LNW1 RABA2B Ras-related protein RABA2b Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJZ5 RABA4E Putative Ras-related protein RABA4e Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MNEEMSGESP ENNKHVKKPT MPEKIDYVFK VVVIGDSAVG KTQLLSRFTH NEFCYDSKST
70 80 90 100 110 120
IGVEFQTRTI TLRGKLVKAQ IWDTAGQERY RAVTSAYYRG ALGAMVVYDI TKRLSFDHVA
130 140 150 160 170 180
RWVEELRAHA DDSAVIMLVG NKADLSVGKR AVPTEDAVEF AETQRLFFSE VSALSGGNVD
190 200 210 220 230
EAFFRLLEEI FSRVVVSRKA MESDGGATVK LDGSRIDVIS GSDLETSNIK EQASCSC