Q9LH50
Gene name |
RABA4D (At3g12160, F28J15.18, T21B14.2) |
Protein name |
Ras-related protein RABA4d |
Names |
AtRABA4d |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G12160 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LH50
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LH50-F1 | Predicted | AlphaFoldDB |
9 variants for Q9LH50
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_3880341_C_T | 33 | A>T | No | 1000Genomes | |
| ENSVATH05815066 | 66 | A>S | No | 1000Genomes | |
| tmp_3_3879812_C_T | 118 | D>N | No | 1000Genomes | |
| ENSVATH05815063 | 122 | V>L | No | 1000Genomes | |
| ENSVATH13903414 | 150 | E>K | No | 1000Genomes | |
| ENSVATH10628506 | 170 | L>F | No | 1000Genomes | |
| ENSVATH05815062 | 187 | A>V | No | 1000Genomes | |
| tmp_3_3879523_T_C | 214 | K>R | No | 1000Genomes | |
| ENSVATH10628505 | 215 | R>S | No | 1000Genomes |
No associated diseases with Q9LH50
1 regional properties for Q9LH50
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 15 - 172 | IPR005225 |
Functions
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| apical part of cell | The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. |
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| exocytic vesicle | A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| pollen tube tip | The region at growing end of the pollen tube cell, where polarized growth occurs. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| kinase binding | Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| pollen tube development | The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure. |
| pollen tube growth | Growth of pollen via tip extension of the intine wall. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of pollen tube growth | Any process that modulates the frequency, rate or extent of pollen tube growth. |
24 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3MHP2 | RAB11B | Ras-related protein Rab-11B | Bos taurus (Bovine) | PR |
| Q2TA29 | RAB11A | Ras-related protein Rab-11A | Bos taurus (Bovine) | PR |
| Q5ZJN2 | RAB11A | Ras-related protein Rab-11A | Gallus gallus (Chicken) | PR |
| Q5ZHV1 | RAB33B | Ras-related protein Rab-33B | Gallus gallus (Chicken) | PR |
| P62490 | RAB11A | Ras-related protein Rab-11A | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| P62491 | RAB11A | Ras-related protein Rab-11A | Homo sapiens (Human) | PR |
| Q15907 | RAB11B | Ras-related protein Rab-11B | Homo sapiens (Human) | PR |
| Q96AX2 | RAB37 | Ras-related protein Rab-37 | Homo sapiens (Human) | PR |
| Q9H082 | RAB33B | Ras-related protein Rab-33B | Homo sapiens (Human) | PR |
| P46638 | Rab11b | Ras-related protein Rab-11B | Mus musculus (Mouse) | PR |
| P62492 | Rab11a | Ras-related protein Rab-11A | Mus musculus (Mouse) | PR |
| Q9JKM7 | Rab37 | Ras-related protein Rab-37 | Mus musculus (Mouse) | PR |
| O35963 | Rab33b | Ras-related protein Rab-33B | Mus musculus (Mouse) | PR |
| Q52NJ1 | RAB11A | Ras-related protein Rab-11A | Sus scrofa (Pig) | PR |
| O35509 | Rab11b | Ras-related protein Rab-11B | Rattus norvegicus (Rat) | PR |
| P62494 | Rab11a | Ras-related protein Rab-11A | Rattus norvegicus (Rat) | PR |
| P25766 | RGP1 | Ras-related protein RGP1 | Oryza sativa subsp japonica (Rice) | PR |
| Q20365 | rab-33 | Ras-related protein Rab-33 | Caenorhabditis elegans | PR |
| O04486 | RABA2A | Ras-related protein RABA2a | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49513 | RABA1E | Ras-related protein RABA1e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FE79 | RABA4C | Ras-related protein RABA4c | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNK1 | RABA3 | Ras-related protein RABA3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNW1 | RABA2B | Ras-related protein RABA2b | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SJZ5 | RABA4E | Putative Ras-related protein RABA4e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNLYGDYNQ | KIDYVFKVVL | IGDSAVGKTQ | LLARFARNEF | SVDSKATIGV | EFQTKTLVID |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKTVKAQIWD | TAGQERYRAV | TSAYYRGAVG | AMLVYDMTKR | QSFDHMAKWL | EELRGHADKN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IVIMLIGNKC | DLGSLRAVPT | EDAQEFAQRE | NLFFMETSAL | EATNVETAFL | TILTEIYRII |
| 190 | 200 | 210 | 220 | ||
| SKKSLTADDD | DADGNSSLLK | GTRIIIPSEQ | ESGKRGGCCG | KS |