Q9LFN6
PR
Gene name |
RH56 (UAP56B, At5g11200, F2I11.90) |
Protein name |
DEAD-box ATP-dependent RNA helicase 56 |
Names |
UAP56 homolog B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G11200 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LFN6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LFN6-F1 | Predicted | AlphaFoldDB |
8 variants for Q9LFN6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_3553409_G_A | 26 | D>N | No | 1000Genomes | |
| ENSVATH10695549 | 29 | N>S | No | 1000Genomes | |
| tmp_5_3553439_G_C | 36 | V>L | No | 1000Genomes | |
| tmp_5_3567497_A_G | 37 | K>E | No | 1000Genomes | |
| tmp_5_3569835_A_C | 271 | S>R | No | 1000Genomes | |
| tmp_5_3555794_A_T | 273 | M>L | No | 1000Genomes | |
| ENSVATH10695669 | 399 | E>V | No | 1000Genomes | |
| ENSVATH06952393 | 423 | T>I | No | 1000Genomes |
No associated diseases with Q9LFN6
4 regional properties for Q9LFN6
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| mRNA transport | The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
29 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q07478 | SUB2 | ATP-dependent RNA helicase SUB2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3T147 | DDX39B | Spliceosome RNA helicase DDX39B | Bos taurus (Bovine) | PR |
| Q5ZHZ0 | DDX39B | Spliceosome RNA helicase DDX39B | Gallus gallus (Chicken) | PR |
| P60024 | DDX39B | Spliceosome RNA helicase DDX39B | Pan troglodytes (Chimpanzee) | PR |
| Q5WR10 | DDX39B | Spliceosome RNA helicase DDX39B | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| O00148 | DDX39A | ATP-dependent RNA helicase DDX39A | Homo sapiens (Human) | PR |
| Q13838 | DDX39B | Spliceosome RNA helicase DDX39B | Homo sapiens (Human) | PR |
| Q8VDW0 | Ddx39a | ATP-dependent RNA helicase DDX39A | Mus musculus (Mouse) | PR |
| Q9Z1N5 | Ddx39b | Spliceosome RNA helicase Ddx39b | Mus musculus (Mouse) | PR |
| Q29024 | DDX39B | Spliceosome RNA helicase DDX39B | Sus scrofa (Pig) | PR |
| Q5U216 | Ddx39a | ATP-dependent RNA helicase DDX39A | Rattus norvegicus (Rat) | PR |
| Q63413 | Ddx39b | Spliceosome RNA helicase Ddx39b | Rattus norvegicus (Rat) | PR |
| Q5TM17 | DDX39B | Spliceosome RNA helicase DDX39B | Macaca mulatta (Rhesus macaque) | PR |
| Q5JK84 | AIP2 | DEAD-box ATP-dependent RNA helicase 15 | Oryza sativa subsp japonica (Rice) | PR |
| Q0JM17 | AIP1 | DEAD-box ATP-dependent RNA helicase 56 | Oryza sativa subsp japonica (Rice) | PR |
| Q18212 | hel-1 | Spliceosome RNA helicase DDX39B homolog | Caenorhabditis elegans | PR |
| Q94A52 | EIF4A3 | Eukaryotic initiation factor 4A-III homolog | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LA13 | RH11 | DEAD-box ATP-dependent RNA helicase 11 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q84W89 | RH37 | DEAD-box ATP-dependent RNA helicase 37 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9M2F9 | RH52 | DEAD-box ATP-dependent RNA helicase 52 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q93ZG7 | RH38 | DEAD-box ATP-dependent RNA helicase 38 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C718 | RH20 | DEAD-box ATP-dependent RNA helicase 20 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56XG6 | RH15 | DEAD-box ATP-dependent RNA helicase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZB4 | RH43 | Putative DEAD-box ATP-dependent RNA helicase 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LU46 | RH35 | DEAD-box ATP-dependent RNA helicase 35 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3E9C3 | RH58 | DEAD-box ATP-dependent RNA helicase 58, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W4R3 | RH30 | DEAD-box ATP-dependent RNA helicase 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8H136 | RH14 | DEAD-box ATP-dependent RNA helicase 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FZ92 | RH44 | Putative DEAD-box ATP-dependent RNA helicase 44 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGDARDNEAY | EEELLDYEEE | DEKVPDSGNK | VNGEAVKKGY | VGIHSSGFRD | FLLKPELLRA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IVDSGFEHPS | EVQHECIPQA | ILGMDVICQA | KSGMGKTAVF | VLSTLQQIEP | SPGQVSALVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CHTRELAYQI | CNEFVRFSTY | LPDTKVSVFY | GGVNIKIHKD | LLKNECPHIV | VGTPGRVLAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AREKDLSLKN | VRHFILDECD | KMLESLDMRR | DVQEIFKMTP | HDKQVMMFSA | TLSKEIRPVC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KKFMQDPMEI | YVDDEAKLTL | HGLVQHYIKL | SEMEKNRKLN | DLLDALDFNQ | VVIFVKSVSR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AAELNKLLVE | CNFPSICIHS | GMSQEERLTR | YKSFKEGHKR | ILVATDLVGR | GIDIERVNIV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| INYDMPDSAD | TYLHRVGRAG | RFGTKGLAIT | FVASASDSEV | LNQVQERFEV | DIKELPEQID |
| TSTYMPS |