Q9JKM7
Gene name |
Rab37 |
Protein name |
Ras-related protein Rab-37 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:58222 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9JKM7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9JKM7-F1 | Predicted | AlphaFoldDB |
No variants for Q9JKM7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9JKM7 | |||||
No associated diseases with Q9JKM7
1 regional properties for Q9JKM7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 29 - 184 | IPR005225 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum-Golgi intermediate compartment | A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| secretory granule | A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96AX2 | RAB37 | Ras-related protein Rab-37 | Homo sapiens (Human) | PR |
| O35963 | Rab33b | Ras-related protein Rab-33B | Mus musculus (Mouse) | PR |
| P25766 | RGP1 | Ras-related protein RGP1 | Oryza sativa subsp japonica (Rice) | PR |
| Q9LNK1 | RABA3 | Ras-related protein RABA3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O04486 | RABA2A | Ras-related protein RABA2a | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LNW1 | RABA2B | Ras-related protein RABA2b | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LH50 | RABA4D | Ras-related protein RABA4d | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FE79 | RABA4C | Ras-related protein RABA4c | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SJZ5 | RABA4E | Putative Ras-related protein RABA4e | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTGTPGAATA | GDGEAPERSP | PFSPNYDLTG | KVMLLGDSGV | GKTCFLIQFK | DGAFLSGTFI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATVGIDSRNK | VVTVDGARVK | LQIWDTAGQE | RFRSVTHAYY | RDAQALLLLY | DITNQSSFDN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRAWLTEIHE | YAQRDVVIML | LGNKADVSSE | RVIRSEDGET | LAREYGVPFM | ETSAKTGMNV |
| 190 | 200 | 210 | 220 | ||
| ELAFLAIAKE | LKYRAGRQPD | EPSFQIRDYV | ESQKKRSSCC | SFV |