AiPD: Autoinhibited Protein Database

Q9HBE1

Gene name	PATZ1 (PATZ, RIAZ, ZBTB19, ZNF278, ZSG)
Protein name	POZ-, AT hook-, and zinc finger-containing protein 1
Names	BTB/POZ domain zinc finger transcription factor, Protein kinase A RI subunit alpha-associated protein, Zinc finger and BTB domain-containing protein 19, Zinc finger protein 278, Zinc finger sarcoma gene protein
Species	Homo sapiens (Human)
KEGG Pathway	hsa:23598
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

170-316 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

170-316 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

6 structures for Q9HBE1

Entry ID	Method	Resolution	Chain	Position	Source
2EPP	NMR	-	A	286-338	PDB
2EPQ	NMR	-	A	380-411	PDB
2EPR	NMR	-	A	350-384	PDB
2EPS	NMR	-	A	408-445	PDB
2YT9	NMR	-	A	355-436	PDB
AF-Q9HBE1-F1	Predicted				AlphaFoldDB

416 variants for Q9HBE1

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs1555894069 CA411258030 RCV000577872	188	D>Y	Ependymoma [ClinVar]	Yes	ClinGen ClinVar Ensembl dbSNP
rs779325614 CA10191740	3	R>P		No	ClinGen ExAC TOPMed gnomAD
CA411260599 rs779325614	3	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA10191739 CA411260573 rs769145099	5	N>K		No	ClinGen ExAC TOPMed gnomAD
CA411260543 rs1601501420	7	A>V		No	ClinGen Ensembl
rs1243192284 CA411260520	9	C>Y		No	ClinGen TOPMed gnomAD
CA10191736 rs756897046	11	P>L		No	ClinGen ExAC TOPMed gnomAD
rs756897046 CA411260488	11	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs756897046 CA411260490	11	P>R		No	ClinGen ExAC TOPMed gnomAD
CA411260493 rs1463292629	11	P>S		No	ClinGen gnomAD
CA411260480 rs1489587238	12	S>A		No	ClinGen TOPMed
COSM1535254 CA10191733 COSM1535253 rs757918024	15	Y>C	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA411260431 rs1244408678	16	T>A		No	ClinGen TOPMed gnomAD
rs1477347086 CA411260396	18	Q>R		No	ClinGen TOPMed
CA10191731 rs765327330	20	S>C		No	ClinGen ExAC TOPMed gnomAD
rs759499623 CA10191730	20	S>N		No	ClinGen ExAC TOPMed gnomAD
CA10191727 rs760831844	28	H>N		No	ClinGen ExAC TOPMed gnomAD
CA411260222 rs1220907735	32	Q>E		No	ClinGen gnomAD
CA10191724 rs199882610	39	R>G		No	ClinGen ExAC gnomAD
TCGA novel	39	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs948820640 CA323293451	49	D>N		No	ClinGen TOPMed
rs746667136 CA10191718	57	A>S		No	ClinGen ExAC gnomAD
TCGA novel	57	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10191712 rs753761567	72	A>S		No	ClinGen ExAC gnomAD
rs1243839645 CA411259748	72	A>V		No	ClinGen TOPMed
rs1486154829 CA411259727	74	L>V		No	ClinGen TOPMed
rs1426725784 CA411259702	76	D>Y		No	ClinGen gnomAD
CA411259683 rs1490927681	77	G>D		No	ClinGen gnomAD
rs1181151045 CA411259686	77	G>S		No	ClinGen TOPMed
rs1204421603 CA411259669	78	G>E		No	ClinGen gnomAD
CA323293358 rs951303344	79	A>P		No	ClinGen TOPMed gnomAD
CA323293359 rs951303344	79	A>T		No	ClinGen TOPMed gnomAD
rs1275164984 CA411259647	80	A>E		No	ClinGen gnomAD
rs764189357 CA10191705	81	D>E		No	ClinGen ExAC gnomAD
rs774451513 CA10191706	81	D>N		No	ClinGen ExAC gnomAD
CA411259606 rs1345908192	83	G>D		No	ClinGen gnomAD
CA10191704 rs369451544	84	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA411259602 rs369451544	84	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA10191703 rs571157358	87	V>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA10191702 rs571157358	87	V>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA411259565 rs1439907946	87	V>I		No	ClinGen gnomAD
rs1403463151 CA411259534	90	A>E		No	ClinGen gnomAD
rs746295130 CA411259527	91	T>K		No	ClinGen ExAC gnomAD
rs746295130 CA10191700	91	T>M		No	ClinGen ExAC gnomAD
CA411259528 rs746295130	91	T>R		No	ClinGen ExAC gnomAD
CA411259521 rs1430390268	92	A>V		No	ClinGen gnomAD
rs777118063 CA10191699	93	A>P		No	ClinGen ExAC TOPMed gnomAD
rs777118063 CA411259520	93	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1469080065 CA411259510	94	P>L		No	ClinGen gnomAD
TCGA novel	96	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411259502 rs1235054261	96	G>R		No	ClinGen TOPMed gnomAD
CA411259503 rs1235054261	96	G>S		No	ClinGen TOPMed gnomAD
rs1460875506 CA411259492	97	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA411259481 rs1335395327	98	A>S		No	ClinGen TOPMed gnomAD
rs867427847 CA16040450	99	G>E		No	ClinGen TOPMed gnomAD
rs1324066135 CA411259441	101	S>T		No	ClinGen gnomAD
rs1221822984 CA411259426	102	R>P		No	ClinGen gnomAD
CA10191697 rs150464548	102	R>W		No	ClinGen ESP ExAC gnomAD
CA411259396 rs1029568227	104	L>V		No	ClinGen TOPMed gnomAD
rs1280012252 CA411259360	106	M>V		No	ClinGen gnomAD
TCGA novel	107	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1446663625 CA411259311	109	I>L		No	ClinGen gnomAD
TCGA novel	111	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs537192097 CA10191694	111	S>P		No	ClinGen ExAC gnomAD
rs1601500842 CA411259229	113	V>A		No	ClinGen Ensembl
rs1478265598 CA411259222	114	F>L		No	ClinGen gnomAD
rs780104367 CA10191693	115	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1317239152 CA411259098	121	A>V		No	ClinGen TOPMed
CA411259090 rs1601500808	122	Y>S		No	ClinGen Ensembl
rs1426107341 CA411259052	125	R>C		No	ClinGen gnomAD
CA411259032 rs1209372422	126	I>M		No	ClinGen TOPMed
CA411258801 rs1241321405	134	P>A		No	ClinGen gnomAD
CA10191688 rs751729539	137	M>V		No	ClinGen ExAC gnomAD
rs1191199632 CA411258757	138	T>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs763163577 CA10191686	141	K>R		No	ClinGen ExAC gnomAD
TCGA novel	147	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411258564 rs1237262395	156	I>L		No	ClinGen TOPMed
rs151337633 CA10191683	158	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	158	Q>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA323293267 rs963559996	159	S>P		No	ClinGen TOPMed
CA411258521 rs1409204858	160	N>H		No	ClinGen TOPMed
rs904236099 CA323293263	161	V>I		No	ClinGen Ensembl
CA411258502 rs1601500699	162	Q>E		No	ClinGen Ensembl
CA10191680 rs747817525	164	L>V		No	ClinGen ExAC TOPMed gnomAD
rs773987880 CA10191679	165	V>I		No	ClinGen ExAC gnomAD
rs1601500658 CA411258455	166	P>H		No	ClinGen Ensembl
rs1041878872 CA323293250	166	P>S		No	ClinGen Ensembl
CA10191677 rs756085184	167	P>A		No	ClinGen ExAC TOPMed gnomAD
rs756085184 CA10191676	167	P>S		No	ClinGen ExAC TOPMed gnomAD
rs756085184 CA10191675	167	P>T		No	ClinGen ExAC TOPMed gnomAD
rs745761343 CA10191674	168	A>T		No	ClinGen ExAC TOPMed gnomAD
CA411258421 rs1160521116	168	A>V		No	ClinGen gnomAD
rs780983818 CA10191673	169	R>H		No	ClinGen ExAC gnomAD
TCGA novel	170	A>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411258382 rs1165580321	171	D>N		No	ClinGen gnomAD
rs1184981383 CA411258350	172	I>M		No	ClinGen TOPMed gnomAD
rs1261309948 CA411258353	172	I>R		No	ClinGen TOPMed gnomAD
CA411258363 rs1444662864	172	I>V		No	ClinGen TOPMed
rs751732552 CA10191671	173	M>I		No	ClinGen ExAC gnomAD
rs1486750390 CA411258337	173	M>T		No	ClinGen gnomAD
rs1275952099 CA411258317	174	L>F		No	ClinGen TOPMed gnomAD
rs201931723 CA10191670	174	L>H		No	ClinGen 1000Genomes ExAC gnomAD
CA411258313 rs201931723	174	L>P		No	ClinGen 1000Genomes ExAC gnomAD
rs1275952099 CA411258320	174	L>V		No	ClinGen TOPMed gnomAD
CA10191668 rs377660548	176	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1246095839 CA411258262	177	P>S		No	ClinGen TOPMed gnomAD
CA411258267 rs1246095839	177	P>T		No	ClinGen TOPMed gnomAD
CA411258244 rs1293082387	178	P>S		No	ClinGen gnomAD
TCGA novel	179	G>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1364583591 CA411258177	181	S>W		No	ClinGen gnomAD
CA10191666 rs760143660	182	D>N		No	ClinGen ExAC gnomAD
rs1305426660 CA411258135	183	L>S		No	ClinGen gnomAD
CA411258113 rs1425440340	184	G>D		No	ClinGen TOPMed gnomAD
rs754338920 CA411258085	185	F>L		No	ClinGen ExAC gnomAD
rs1430547720 CA411258067	186	P>H		No	ClinGen gnomAD
CA10191664 rs766857189	186	P>S		No	ClinGen ExAC gnomAD
rs200029692 CA10191663	189	M>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA323293206 rs758855130	191	N>K		No	ClinGen TOPMed
rs376402631 CA10191662	191	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs192346045 CA10191660	193	A>E		No	ClinGen 1000Genomes ExAC
CA411257956 rs1357990949	193	A>T		No	ClinGen gnomAD
CA411257924 rs1271037881	194	A>P		No	ClinGen gnomAD
rs1470501508 CA411257871	196	A>V		No	ClinGen TOPMed
CA411257844 rs1480048429	198	N>D		No	ClinGen gnomAD
rs775093394 CA10191659	198	N>S		No	ClinGen ExAC gnomAD
CA10191658 rs769240946	199	S>G		No	ClinGen ExAC gnomAD
CA10191657 rs745816246	199	S>R		No	ClinGen ExAC TOPMed gnomAD
CA411257789 rs1282168710	200	N>S		No	ClinGen TOPMed gnomAD
CA411257791 rs1282168710	200	N>T		No	ClinGen TOPMed gnomAD
CA10191654 rs777404081	203	A>D		No	ClinGen ExAC gnomAD
CA10191653 rs777404081	203	A>G		No	ClinGen ExAC gnomAD
rs770844249 CA10191655	203	A>T		No	ClinGen ExAC gnomAD
rs939636305 CA323293166	204	G>R		No	ClinGen TOPMed
rs1349385267 CA411257661	206	M>L		No	ClinGen TOPMed
CA10191651 rs752814411	208	P>A		No	ClinGen ExAC TOPMed gnomAD
rs752814411 CA411257595	208	P>S		No	ClinGen ExAC TOPMed gnomAD
rs201260359 CA10191650	209	E>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA411257544 rs1355353578	210	E>D		No	ClinGen gnomAD
rs201570433 CA10191648	211	E>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201570433 CA10191649	211	E>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA10191647 rs767049429	212	A>T		No	ClinGen ExAC gnomAD
rs5753567 CA323293152	213	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs750839896 CA10191644	215	A>G		No	ClinGen ExAC TOPMed gnomAD
rs767733108 CA10191643	216	A>G		No	ClinGen ExAC TOPMed gnomAD
CA411257437 rs767733108	216	A>V		No	ClinGen ExAC TOPMed gnomAD
CA10191641 rs774943024	217	G>A		No	ClinGen ExAC TOPMed
rs1039805766 CA323293101	219	A>P		No	ClinGen TOPMed gnomAD
rs776099266 CA10191638	220	I>T		No	ClinGen ExAC gnomAD
CA10191637 rs770898996	221	A>E		No	ClinGen ExAC TOPMed gnomAD
rs1393275111 CA411257338	222	G>D		No	ClinGen gnomAD
CA10191635 rs777649297	223	Q>R		No	ClinGen ExAC gnomAD
rs909941855 CA323293072	224	A>D		No	ClinGen Ensembl
CA411257307 rs1476481033	224	A>T		No	ClinGen TOPMed
rs983301383 CA323293064	225	S>F		No	ClinGen TOPMed
rs779345295 CA10191632	227	P>A		No	ClinGen ExAC gnomAD
TCGA novel	227	P>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10191633 rs779345295	227	P>S		No	ClinGen ExAC gnomAD
rs982546198 CA323293060	228	V>M		No	ClinGen TOPMed
rs755239284 CA10191631	229	L>F		No	ClinGen ExAC gnomAD
CA411257223 rs112736081	230	P>A		No	ClinGen gnomAD
rs1362004321 CA411257218	230	P>L		No	ClinGen gnomAD
CA323293053 rs112736081	230	P>S		No	ClinGen gnomAD
CA10191630 rs754017917	231	G>R		No	ClinGen ExAC TOPMed gnomAD
CA411257164 rs1367333739	233	D>E		No	ClinGen TOPMed
TCGA novel	234	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA323293027 rs139880845	237	M>I		No	ClinGen ESP TOPMed
TCGA novel	237	M>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759798320 CA323293032	237	M>V		No	ClinGen gnomAD
CA10191628 rs756676378	239	A>V		No	ClinGen ExAC gnomAD
CA411256967 rs764921895	247	L>V		No	ClinGen ExAC gnomAD
rs776154161 CA10191621	250	P>L		No	ClinGen ExAC gnomAD
rs1178679282 CA411256862	253	S>T		No	ClinGen gnomAD
rs760674853 CA10191619	255	A>V		No	ClinGen ExAC TOPMed gnomAD
rs772956682 CA10191618	257	S>G		No	ClinGen ExAC TOPMed gnomAD
rs772043087 CA10191617	258	A>T		No	ClinGen ExAC TOPMed gnomAD
CA411256762 rs1293358661	259	P>L		No	ClinGen TOPMed
CA10191615 rs556606786	260	P>R		No	ClinGen 1000Genomes ExAC gnomAD
CA411256738 rs747954119	260	P>S		No	ClinGen ExAC TOPMed gnomAD
CA10191616 rs747954119	260	P>T		No	ClinGen ExAC TOPMed gnomAD
CA411256725 rs1192023392	261	L>M		No	ClinGen gnomAD
CA411256700 rs372045905	262	T>I		No	ClinGen ExAC TOPMed gnomAD
rs372045905 CA10191614	262	T>S		No	ClinGen ExAC TOPMed gnomAD
rs1260060457 CA411256680	263	G>A		No	ClinGen gnomAD
rs1243887430 CA411256608	267	R>Q		No	ClinGen gnomAD
CA411256613 rs1197547641	267	R>W		No	ClinGen gnomAD
TCGA novel	268	G>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10191611 rs756086166	269	R>C		No	ClinGen ExAC gnomAD
CA411256517 rs1291022540	272	K>R		No	ClinGen gnomAD
rs781613235 CA10191609	273	A>G		No	ClinGen ExAC gnomAD
CA10191608 rs201619813	274	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs1385964896 CA411256479	274	N>S		No	ClinGen TOPMed
rs201619813 CA411256483	274	N>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs1425155789 CA411256450	276	L>P		No	ClinGen TOPMed
CA10191605 rs149942239	281	G>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs753435299 CA10191604	284	G>R		No	ClinGen ExAC gnomAD
CA411256358 rs1374394586	285	G>D		No	ClinGen gnomAD
rs765918502 CA10191603	285	G>S		No	ClinGen ExAC gnomAD
rs1478318860 CA411256349	286	L>P		No	ClinGen gnomAD
rs772767747 CA10191601	287	R>K		No	ClinGen ExAC TOPMed gnomAD
rs1220896941 CA411256292	290	G>A		No	ClinGen gnomAD
rs1601499763 CA411256298	290	G>S		No	ClinGen Ensembl
CA323292880 rs1036218137	291	I>F		No	ClinGen TOPMed
rs767405982 CA10191600	292	L>F		No	ClinGen ExAC gnomAD
TCGA novel	292	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1359541225 CA411256245	294	C>Y		No	ClinGen TOPMed
rs1219077456 CA411256184	299	K>E		No	ClinGen gnomAD
CA411256178 rs1255937062	299	K>R		No	ClinGen TOPMed
rs775784085 CA10191595	303	D>E		No	ClinGen ExAC gnomAD
rs1350350178 CA411256103	304	A>D		No	ClinGen TOPMed gnomAD
rs1350350178 CA411256104	304	A>G		No	ClinGen TOPMed gnomAD
CA10191594 rs770048474	305	N>Y		No	ClinGen ExAC gnomAD
rs1407647587 CA411256082	306	R>Q		No	ClinGen gnomAD
rs1466527720 CA411256011	312	A>T		No	ClinGen TOPMed gnomAD
rs1428986944 CA411256006	312	A>V		No	ClinGen gnomAD
CA411255971 rs1479300645	315	G>S		No	ClinGen gnomAD
rs758695589 CA411255924	318	S>R		No	ClinGen ExAC gnomAD
CA411255916 rs1260313912	319	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs779631426 CA411255887	321	L>M		No	ClinGen ExAC gnomAD
rs779631426 CA10191586	321	L>V		No	ClinGen ExAC gnomAD
rs1405102519 CA411255878	322	G>C		No	ClinGen TOPMed
CA411255872 rs1261048225	322	G>D		No	ClinGen gnomAD
rs1368220608 CA411255824	326	L>V		No	ClinGen gnomAD
rs775182258 CA323292815	328	P>L		No	ClinGen Ensembl
CA10191583 rs150800318	328	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1331663097 CA411255792	329	P>L		No	ClinGen gnomAD
CA10191582 rs761863287	330	R>K		No	ClinGen ExAC gnomAD
rs201313815 CA411255786	330	R>S		No	ClinGen ExAC TOPMed gnomAD
CA411255780 rs1569029821	332	G>S		No	ClinGen Ensembl
CA411255744 rs762905449	334	N>K		No	ClinGen ExAC TOPMed gnomAD
CA411255712 rs1468705290	337	P>L		No	ClinGen gnomAD
CA411255702 rs1240081670	338	I>T		No	ClinGen gnomAD
rs1240415751 CA411255688	339	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA10191577 rs769956909	340	E>D		No	ClinGen ExAC TOPMed gnomAD
rs117544183 CA10191576	342	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	344	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA323292796 rs1003673752	344	G>S		No	ClinGen TOPMed gnomAD
CA10191574 rs770944229	345	P>T		No	ClinGen ExAC
rs868307640 CA323292790	346	R>*		No	ClinGen Ensembl
CA411255600 rs1221970284	346	R>Q		No	ClinGen gnomAD
CA10191573 rs747522781	347	K>R		No	ClinGen ExAC TOPMed gnomAD
rs1309376588 CA411255559	349	S>N		No	ClinGen TOPMed gnomAD
rs1569029753 CA411255547	350	R>Q		No	ClinGen Ensembl
CA10191572 rs778319471	350	R>W		No	ClinGen ExAC gnomAD
rs905413876 CA323292780	358	E>D		No	ClinGen gnomAD
CA411255430 rs1338283906	359	I>F		No	ClinGen gnomAD
rs1450724213 CA411255428	359	I>T		No	ClinGen gnomAD
rs1399489261 CA411255399	361	G>D		No	ClinGen gnomAD
rs571660220 CA10191570	361	G>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1159333264 CA411255384	362	K>N		No	ClinGen gnomAD
rs779306937 CA10191569	362	K>R		No	ClinGen ExAC gnomAD
rs755751672 COSM3708211 CA323292768 COSM3708210	363	I>L	liver [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs755751672 CA10191568	363	I>V		No	ClinGen ExAC gnomAD
rs752468793 CA10191561	375	L>Q		No	ClinGen ExAC gnomAD
CA411255215 rs762958946	375	L>V		No	ClinGen ExAC gnomAD
CA10191558 rs369840930	386	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	389	G>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771138297 CA10191557	391	R>Q		No	ClinGen ExAC gnomAD
CA10191555 rs201064434	400	Y>F		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	401	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748646348 CA10191553	402	V>A		No	ClinGen ExAC gnomAD
rs772609155 CA10191554	402	V>L		No	ClinGen ExAC TOPMed gnomAD
CA411254768 rs1184563521	409	V>L		No	ClinGen TOPMed gnomAD
rs1209377481 CA411254701	414	I>V		No	ClinGen TOPMed
CA411254614 rs1489668430	419	G>E		No	ClinGen gnomAD
CA411253657 rs746613842	429	N>K		No	ClinGen ExAC gnomAD
CA411253585 rs1342944014	435	V>M		No	ClinGen TOPMed
rs1176696590 CA411253485	440	R>W		No	ClinGen gnomAD
rs867098952 CA323291969	441	P>L		No	ClinGen Ensembl
CA323291973 rs867858071	441	P>S		No	ClinGen Ensembl
rs529473707 CA10191524	442	H>Y		No	ClinGen 1000Genomes ExAC gnomAD
rs201843871 CA10191523	443	K>R		No	ClinGen 1000Genomes ExAC gnomAD
CA411250994 rs146659012	446	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA10191429 rs146659012	446	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs759027914 CA10191428	448	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs753366928 CA10191427	449	A>T		No	ClinGen ExAC gnomAD
rs766268183 CA10191426	450	S>A		No	ClinGen ExAC gnomAD
rs371330622 CA10191425	452	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs371330622 CA411250908	452	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs541895354 CA323289267	456	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA411250837 rs1222871755	458	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1601489513 CA411250815	460	H>P		No	ClinGen Ensembl
CA323289265 rs952743488	465	E>Q		No	ClinGen TOPMed
CA10191424 rs772907908	467	K>R		No	ClinGen ExAC gnomAD
rs771937261 CA10191423 CA323289261	468	V>L		No	ClinGen ExAC
CA411250712 rs1190908734	469	P>S		No	ClinGen TOPMed
CA411250682 rs1249078992	471	Q>*		No	ClinGen TOPMed
CA411250659 rs1161929979	472	V>A		No	ClinGen TOPMed
rs768984900 CA10191422	478	R>G		No	ClinGen ExAC gnomAD
CA10191419 rs749372022	478	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
COSM86300 rs768984900 CA10191420	478	R>W	ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1263741903 CA411250548	482	M>I		No	ClinGen gnomAD
CA10191418 rs780147447	483	A>S		No	ClinGen ExAC gnomAD
CA411250451 rs1248140955	489	H>D		No	ClinGen gnomAD
CA411250396 rs1221822474	492	G>E		No	ClinGen gnomAD
rs1257859719 CA411250383 COSM1033441	494	S>G	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA323289247 rs144623786	498	S>G		No	ClinGen ESP
CA411250305 rs1296899687	499	I>M		No	ClinGen gnomAD
rs757549460 CA10191414	499	I>N		No	ClinGen ExAC gnomAD
CA411250273 rs1165320794	501	N>K		No	ClinGen TOPMed
rs751909410 CA411250271	502	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs751909410 CA10191413	502	R>G		No	ClinGen ExAC gnomAD
CA411250267 rs1365539466	502	R>L		No	ClinGen TOPMed gnomAD
rs1365539466 CA411250261	502	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs747413910 CA10191393	508	S>F		No	ClinGen ExAC gnomAD
TCGA novel	509	Y>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411249118 rs1468867855	512	V>A		No	ClinGen gnomAD
CA10191391 rs754612369	513	H>L		No	ClinGen ExAC
rs778072249 CA10191392	513	H>N		No	ClinGen ExAC
CA323287115 rs985966399	516	T>I		No	ClinGen TOPMed
rs1176170019 CA16040447	518	H>D		No	ClinGen TOPMed gnomAD
rs1412403219 CA411249029	519	G>A		No	ClinGen TOPMed
CA10191390 rs753477064	519	G>S		No	ClinGen ExAC TOPMed gnomAD
CA411248986 rs1338058112	523	P>T		No	ClinGen TOPMed
CA10191388 rs779437085	525	V>I		No	ClinGen ExAC gnomAD
rs1463746249 CA411248928	526	S>F		No	ClinGen gnomAD
rs755720310 CA411248894	528	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs1482564265 CA411248871	530	E>K		No	ClinGen gnomAD
TCGA novel	532	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411248780 rs1211775089	535	G>W		No	ClinGen gnomAD
CA10191385 rs767609443	537	A>T		No	ClinGen ExAC gnomAD
CA411248722 rs1307668855	538	A>T		No	ClinGen TOPMed
rs1242620784 CA411248711	538	A>V		No	ClinGen TOPMed gnomAD
TCGA novel	539	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1311754105 CA411248681	541	C>Y		No	ClinGen gnomAD
CA411248666 rs1381320598	542	A>T		No	ClinGen gnomAD
CA411248648 rs1343057460	543	R>G		No	ClinGen TOPMed
CA323287098 rs1012444924	544	T>I		No	ClinGen Ensembl
CA10191382 rs772977984	545	Y>*		No	ClinGen ExAC gnomAD
rs763899965 CA10191381	546	G>V		No	ClinGen ExAC gnomAD
CA411248392 rs1375249952	551	Q>E		No	ClinGen TOPMed
CA411248337 rs1462951941	554	S>L		No	ClinGen TOPMed
rs1601480503 CA411248287	557	D>A		No	ClinGen Ensembl
rs758278573 CA10191359	558	P>L		No	ClinGen ExAC TOPMed gnomAD
rs758278573 CA411248268	558	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs1196012954 CA411248239	561	S>N		No	ClinGen TOPMed gnomAD
rs1361552921 CA411248237	561	S>R		No	ClinGen TOPMed
rs765537425 CA10191357	565	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs765537425 CA411248212	565	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA411248213 rs765537425	565	Y>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	568	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411248186 rs1358676308	569	S>L		No	ClinGen gnomAD
CA10191354 rs766392086	573	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs761178965 CA10191353	576	T>M		No	ClinGen ExAC gnomAD
TCGA novel	577	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773838459 CA10191352	578	E>A		No	ClinGen ExAC gnomAD
rs546530691 CA10191351	579	K>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1388187133 CA411248110	580	Q>H		No	ClinGen gnomAD
rs1465424237 CA411248096	582	A>G		No	ClinGen gnomAD
CA10191350 rs748591221	582	A>T		No	ClinGen ExAC gnomAD
CA411248091 rs1356999048	583	N>S		No	ClinGen TOPMed
CA10191346 rs371277923	589	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1253798671 CA411248040	590	M>I		No	ClinGen gnomAD
CA10191345 rs539046075	593	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1449590980 CA411247975	599	S>F		No	ClinGen TOPMed
CA10191342 rs755612777	599	S>P		No	ClinGen ExAC gnomAD
rs1234716436 CA411247957	602	E>G		No	ClinGen gnomAD
CA323286336 rs1024120922	602	E>K		No	ClinGen Ensembl
rs1446559552 CA411247939	604	K>N		No	ClinGen gnomAD
TCGA novel	604	K>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1308075486 CA411247943	604	K>*		No	ClinGen gnomAD
CA411247936 rs1398525820	605	Y>H		No	ClinGen gnomAD
rs753995897 CA10191338	607	C>R		No	ClinGen ExAC
rs142593910 CA323286316	608	P>L		No	ClinGen ESP TOPMed
CA10191337 rs766586733	608	P>S		No	ClinGen ExAC gnomAD
rs1344789826 CA411247878	613	F>C		No	ClinGen TOPMed
CA323286313 rs189173906	613	F>L		No	ClinGen 1000Genomes
CA411247864 rs1451926824	615	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA411247842 rs1290905233	618	S>C		No	ClinGen TOPMed
rs760806827 CA323286308	624	I>L		No	ClinGen ExAC gnomAD
rs1455631637 CA411247800	624	I>T		No	ClinGen gnomAD
rs760806827 CA10191336	624	I>V		No	ClinGen ExAC gnomAD
rs750451478 CA10191335	626	K>E		No	ClinGen ExAC gnomAD
rs1385720611 CA411247780	627	V>L		No	ClinGen TOPMed
CA323286286 rs1004440139	628	H>Y		No	ClinGen TOPMed gnomAD
rs994508743 CA323286273	630	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA10191332 rs774798984	630	R>W		No	ClinGen ExAC gnomAD
rs769081086 CA10191331	631	A>G		No	ClinGen ExAC gnomAD
rs1247809702 CA411247760	631	A>T		No	ClinGen TOPMed
rs374359865 CA10191329	633	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs746577638 CA411247740	634	G>A		No	ClinGen ExAC gnomAD
rs746577638 CA10191327	634	G>V		No	ClinGen ExAC gnomAD
CA10191325 rs563070496	636	L>P		No	ClinGen 1000Genomes ExAC gnomAD
rs549326827 CA10191322	638	D>E		No	ClinGen 1000Genomes ExAC gnomAD
rs778687462 CA10191323	638	D>N		No	ClinGen ExAC TOPMed gnomAD
rs778687462 CA411247722	638	D>Y		No	ClinGen ExAC TOPMed gnomAD
CA323286232 rs911666881	639	L>V		No	ClinGen Ensembl
rs368152891 CA10191321	641	P>A		No	ClinGen ESP ExAC gnomAD
CA411247697 rs1410371081	642	A>V		No	ClinGen gnomAD
rs1177633015 CA411247660	648	S>C		No	ClinGen gnomAD
TCGA novel	650	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA411247652 rs1444571554	650	Q>K		No	ClinGen gnomAD
rs2240426 CA323286226	663	I>S		No	ClinGen Ensembl
rs1161547128 CA411247508	665	Q>E		No	ClinGen TOPMed
rs751943596 CA10191315	666	S>L		No	ClinGen ExAC TOPMed gnomAD
rs763469287 COSM273076 CA10191313	669	A>V	Variant assessed as Somatic; 0.0 impact. large_intestine haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA411247431 rs1303403341	670	S>A		No	ClinGen TOPMed
CA10191311 rs770739464	671	S>Y		No	ClinGen ExAC gnomAD
rs760197285 CA10191310	673	V>A		No	ClinGen ExAC gnomAD
CA323286207 rs2240425	674	D>E		No	ClinGen Ensembl
CA411247368 rs1356589851	674	D>Y		No	ClinGen gnomAD
rs568056532 CA10191309	675	P>A		No	ClinGen ExAC TOPMed gnomAD
rs568056532 CA323286198	675	P>S		No	ClinGen ExAC TOPMed gnomAD
rs771418683 CA10191308	676	E>K		No	ClinGen ExAC gnomAD
CA10191307 rs540767601	677	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs768562503 CA10191305	679	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs779781336 CA10191303	681	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1262311351 CA411247228	682	M>K		No	ClinGen gnomAD
rs936275018 CA323286168	682	M>V		No	ClinGen TOPMed gnomAD
CA10191302 rs756377516	683	G>E		No	ClinGen ExAC gnomAD
CA411247208 rs1260734092	683	G>R		No	ClinGen TOPMed
rs1242378341 CA411247198	684	P>T		No	ClinGen gnomAD
rs2240424 CA411247167 VAR_052724 CA10191301	685	E>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD UniProt dbSNP
CA411247175 rs1220403013	685	E>G		No	ClinGen gnomAD
rs144494015 CA411247154	686	G>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144494015 CA10191300	686	G>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144494015 CA16040448	686	G>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD

No associated diseases with Q9HBE1

2 regional properties for Q9HBE1

Type	Name	Position	InterPro Accession
domain	Kinesin motor domain	3 - 349	IPR001752
conserved_site	Kinesin motor domain, conserved site	238 - 249	IPR019821

Functions

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
male germ cell nucleus	The nucleus of a male germ cell, a reproductive cell in males.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

6 GO annotations of molecular function

Name	Definition
chromatin binding	Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription repressor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding	Binding to a metal ion.
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
ubiquitin protein ligase binding	Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.

8 GO annotations of biological process

Name	Definition
male gonad development	The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
negative regulation of DNA-templated transcription	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
negative regulation of endothelial cell migration	Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
positive regulation of DNA-templated transcription	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
spermatogenesis	The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
T cell differentiation	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.

177 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q08DS3	OSR1	Protein odd-skipped-related 1	Bos taurus (Bovine)	PR
Q2VWH6	FEZF2	Fez family zinc finger protein 2	Bos taurus (Bovine)	PR
A6QNZ0	ZSCAN26	Zinc finger and SCAN domain-containing protein 26	Bos taurus (Bovine)	PR
A7MBI1	ZFP69	Zinc finger protein 69 homolog	Bos taurus (Bovine)	PR
Q08705	CTCF	Transcriptional repressor CTCF	Gallus gallus (Chicken)	PR
O42409	GFI1B	Zinc finger protein Gfi-1b	Gallus gallus (Chicken)	PR
A2T6W2	ZNF449	Zinc finger protein 449	Pan troglodytes (Chimpanzee)	PR
Q9U405	grau	Transcription factor grauzone	Drosophila melanogaster (Fruit fly)	PR
Q7K0S9	sug	Zinc finger protein GLIS2 homolog	Drosophila melanogaster (Fruit fly)	PR
P20385	Cf2	Chorion transcription factor Cf2	Drosophila melanogaster (Fruit fly)	PR
Q86P48	ATbp	AT-rich binding protein	Drosophila melanogaster (Fruit fly)	PR
P28698	MZF1	Myeloid zinc finger 1	Homo sapiens (Human)	PR
Q9NTW7	ZFP64	Zinc finger protein 64	Homo sapiens (Human)	PR
O14978	ZNF263	Zinc finger protein 263	Homo sapiens (Human)	PR
O60304	ZNF500	Zinc finger protein 500	Homo sapiens (Human)	PR
P08151	GLI1	Zinc finger protein GLI1	Homo sapiens (Human)	PR
Q9UFB7	ZBTB47	Zinc finger and BTB domain-containing protein 47	Homo sapiens (Human)	PR
P18146	EGR1	Early growth response protein 1	Homo sapiens (Human)	PR
Q9Y5W3	KLF2	Krueppel-like factor 2	Homo sapiens (Human)	PR
Q9UNY5	ZNF232	Zinc finger protein 232	Homo sapiens (Human)	PR
Q96SZ4	ZSCAN10	Zinc finger and SCAN domain-containing protein 10	Homo sapiens (Human)	PR
P17028	ZNF24	Zinc finger protein 24	Homo sapiens (Human)	PR
P57682	KLF3	Krueppel-like factor 3	Homo sapiens (Human)	PR
P25490	YY1	Transcriptional repressor protein YY1	Homo sapiens (Human)	SS
O43296	ZNF264	Zinc finger protein 264	Homo sapiens (Human)	PR
P49711	CTCF	Transcriptional repressor CTCF	Homo sapiens (Human)	PR
Q9NQX1	PRDM5	PR domain zinc finger protein 5	Homo sapiens (Human)	PR
Q8TAX0	OSR1	Protein odd-skipped-related 1	Homo sapiens (Human)	PR
Q9UL58	ZNF215	Zinc finger protein 215	Homo sapiens (Human)	PR
Q8TBJ5	FEZF2	Fez family zinc finger protein 2	Homo sapiens (Human)	PR
Q96SR6	ZNF382	Zinc finger protein 382	Homo sapiens (Human)	PR
Q96IT1	ZNF496	Zinc finger protein 496	Homo sapiens (Human)	PR
Q96N95	ZNF396	Zinc finger protein 396	Homo sapiens (Human)	PR
Q9ULJ3	ZBTB21	Zinc finger and BTB domain-containing protein 21	Homo sapiens (Human)	PR
O75840	KLF7	Krueppel-like factor 7	Homo sapiens (Human)	PR
Q9H9D4	ZNF408	Zinc finger protein 408	Homo sapiens (Human)	PR
Q13127	REST	RE1-silencing transcription factor	Homo sapiens (Human)	PR
Q8IZM8	ZNF654	Zinc finger protein 654	Homo sapiens (Human)	PR
Q14526	HIC1	Hypermethylated in cancer 1 protein	Homo sapiens (Human)	PR
P17022	ZNF18	Zinc finger protein 18	Homo sapiens (Human)	PR
Q86XF7	ZNF575	Zinc finger protein 575	Homo sapiens (Human)	PR
Q06889	EGR3	Early growth response protein 3	Homo sapiens (Human)	PR
Q8NAM6	ZSCAN4	Zinc finger and SCAN domain-containing protein 4	Homo sapiens (Human)	PR
Q08ER8	ZNF543	Zinc finger protein 543	Homo sapiens (Human)	PR
P17029	ZKSCAN1	Zinc finger protein with KRAB and SCAN domains 1	Homo sapiens (Human)	PR
O95625	ZBTB11	Zinc finger and BTB domain-containing protein 11	Homo sapiens (Human)	PR
Q9NPC7	MYNN	Myoneurin	Homo sapiens (Human)	PR
Q96BV0	ZNF775	Zinc finger protein 775	Homo sapiens (Human)	PR
Q8NF99	ZNF397	Zinc finger protein 397	Homo sapiens (Human)	PR
Q63HK3	ZKSCAN2	Zinc finger protein with KRAB and SCAN domains 2	Homo sapiens (Human)	PR
Q5FWF6	ZNF789	Zinc finger protein 789	Homo sapiens (Human)	PR
Q15776	ZKSCAN8	Zinc finger protein with KRAB and SCAN domains 8	Homo sapiens (Human)	PR
Q53GI3	ZNF394	Zinc finger protein 394	Homo sapiens (Human)	PR
O95125	ZNF202	Zinc finger protein 202	Homo sapiens (Human)	PR
Q05516	ZBTB16	Zinc finger and BTB domain-containing protein 16	Homo sapiens (Human)	PR
Q9H116	GZF1	GDNF-inducible zinc finger protein 1	Homo sapiens (Human)	PR
Q8N0Y2	ZNF444	Zinc finger protein 444	Homo sapiens (Human)	PR
Q6P9G9	ZNF449	Zinc finger protein 449	Homo sapiens (Human)	PR
Q8IW36	ZNF695	Zinc finger protein 695	Homo sapiens (Human)	PR
Q5VTD9	GFI1B	Zinc finger protein Gfi-1b	Homo sapiens (Human)	PR
Q6PG37	ZNF790	Zinc finger protein 790	Homo sapiens (Human)	PR
Q9NQV6	PRDM10	PR domain zinc finger protein 10	Homo sapiens (Human)	PR
Q9Y2D9	ZNF652	Zinc finger protein 652	Homo sapiens (Human)	PR
Q9Y4E5	ZNF451	E3 SUMO-protein ligase ZNF451	Homo sapiens (Human)	PR
Q8ND82	ZNF280C	Zinc finger protein 280C	Homo sapiens (Human)	PR
Q49AA0	ZFP69	Zinc finger protein 69 homolog	Homo sapiens (Human)	PR
O43298	ZBTB43	Zinc finger and BTB domain-containing protein 43	Homo sapiens (Human)	PR
P51508	ZNF81	Zinc finger protein 81	Homo sapiens (Human)	PR
Q5JNZ3	ZNF311	Zinc finger protein 311	Homo sapiens (Human)	PR
Q9BRR0	ZKSCAN3	Zinc finger protein with KRAB and SCAN domains 3	Homo sapiens (Human)	PR
Q969J2	ZKSCAN4	Zinc finger protein with KRAB and SCAN domains 4	Homo sapiens (Human)	PR
P49910	ZNF165	Zinc finger protein 165	Homo sapiens (Human)	PR
Q9Y4X4	KLF12	Krueppel-like factor 12	Homo sapiens (Human)	PR
P10074	ZBTB48	Telomere zinc finger-associated protein	Homo sapiens (Human)	PR
P17010	ZFX	Zinc finger X-chromosomal protein	Homo sapiens (Human)	PR
Q9H5H4	ZNF768	Zinc finger protein 768	Homo sapiens (Human)	PR
Q6NSZ9	ZSCAN25	Zinc finger and SCAN domain-containing protein 25	Homo sapiens (Human)	PR
Q9Y2L8	ZKSCAN5	Zinc finger protein with KRAB and SCAN domains 5	Homo sapiens (Human)	PR
Q86UZ6	ZBTB46	Zinc finger and BTB domain-containing protein 46	Homo sapiens (Human)	PR
Q9NX65	ZSCAN32	Zinc finger and SCAN domain-containing protein 32	Homo sapiens (Human)	PR
O14771	ZNF213	Zinc finger protein 213	Homo sapiens (Human)	PR
Q8IWY8	ZSCAN29	Zinc finger and SCAN domain-containing protein 29	Homo sapiens (Human)	PR
Q8NCP5	ZBTB44	Zinc finger and BTB domain-containing protein 44	Homo sapiens (Human)	PR
Q9NQX0	PRDM6	Putative histone-lysine N-methyltransferase PRDM6	Homo sapiens (Human)	PR
Q9BU19	ZNF692	Zinc finger protein 692	Homo sapiens (Human)	PR
Q08AG5	ZNF844	Zinc finger protein 844	Homo sapiens (Human)	PR
Q6R2W3	ZBED9	SCAN domain-containing protein 3	Homo sapiens (Human)	PR
P98182	ZNF200	Zinc finger protein 200	Homo sapiens (Human)	PR
Q9UK11	ZNF223	Zinc finger protein 223	Homo sapiens (Human)	PR
O15156	ZBTB7B	Zinc finger and BTB domain-containing protein 7B	Homo sapiens (Human)	PR
Q6ZMS7	ZNF783	Zinc finger protein 783	Homo sapiens (Human)	PR
P59923	ZNF445	Zinc finger protein 445	Homo sapiens (Human)	PR
Q8N859	ZNF713	Zinc finger protein 713	Homo sapiens (Human)	PR
Q99612	KLF6	Krueppel-like factor 6	Homo sapiens (Human)	PR
Q8TD17	ZNF398	Zinc finger protein 398	Homo sapiens (Human)	PR
A6NGD5	ZSCAN5C	Zinc finger and SCAN domain-containing protein 5C	Homo sapiens (Human)	PR
Q05215	EGR4	Early growth response protein 4	Homo sapiens (Human)	PR
Q7Z398	ZNF550	Zinc finger protein 550	Homo sapiens (Human)	PR
Q96N20	ZNF75A	Zinc finger protein 75A	Homo sapiens (Human)	PR
A6NJL1	ZSCAN5B	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	PR
A1YPR0	ZBTB7C	Zinc finger and BTB domain-containing protein 7C	Homo sapiens (Human)	PR
Q9NWS9	ZNF446	Zinc finger protein 446	Homo sapiens (Human)	PR
Q96N38	ZNF714	Zinc finger protein 714	Homo sapiens (Human)	PR
Q86YH2	ZNF280B	Zinc finger protein 280B	Homo sapiens (Human)	PR
Q9Y2K1	ZBTB1	Zinc finger and BTB domain-containing protein 1	Homo sapiens (Human)	PR
P24278	ZBTB25	Zinc finger and BTB domain-containing protein 25	Homo sapiens (Human)	PR
Q8N680	ZBTB2	Zinc finger and BTB domain-containing protein 2	Homo sapiens (Human)	PR
P41182	BCL6	B-cell lymphoma 6 protein	Homo sapiens (Human)	PR
Q9Y330	ZBTB12	Zinc finger and BTB domain-containing protein 12	Homo sapiens (Human)	PR
Q5TC79	ZBTB37	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	PR
P52739	ZNF131	Zinc finger protein 131	Homo sapiens (Human)	PR
Q13105	ZBTB17	Zinc finger and BTB domain-containing protein 17	Homo sapiens (Human)	PR
O08584	Klf6	Krueppel-like factor 6	Mus musculus (Mouse)	PR
Q61164	Ctcf	Transcriptional repressor CTCF	Mus musculus (Mouse)	PR
Q810A1	Znf18	Zinc finger protein 18	Mus musculus (Mouse)	PR
Q8BGS3	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Mus musculus (Mouse)	PR
Q00899	Yy1	Transcriptional repressor protein YY1	Mus musculus (Mouse)	PR
P41183	Bcl6	B-cell lymphoma 6 protein homolog	Mus musculus (Mouse)	PR
Q9DAI4	Zbtb43	Zinc finger and BTB domain-containing protein 43	Mus musculus (Mouse)	PR
O70237	Gfi1b	Zinc finger protein Gfi-1b	Mus musculus (Mouse)	PR
Q99KZ6	Znf639	Zinc finger protein 639	Mus musculus (Mouse)	PR
Q9Z1D9	Znf394	Zinc finger protein 394	Mus musculus (Mouse)	PR
Q9CXE0	Prdm5	PR domain zinc finger protein 5	Mus musculus (Mouse)	PR
P43300	Egr3	Early growth response protein 3	Mus musculus (Mouse)	PR
Q9DAU9	Znf654	Zinc finger protein 654	Mus musculus (Mouse)	PR
Q9R1Y5	Hic1	Hypermethylated in cancer 1 protein	Mus musculus (Mouse)	PR
Q8R0T2	Znf768	Zinc finger protein 768	Mus musculus (Mouse)	PR
Q9WVG7	Osr1	Protein odd-skipped-related 1	Mus musculus (Mouse)	PR
Q8BI73	Znf775	Zinc finger protein 775	Mus musculus (Mouse)	PR
Q8VCZ7	Zbtb7c	Zinc finger and BTB domain-containing protein 7C	Mus musculus (Mouse)	PR
Q91VN1	Znf24	Zinc finger protein 24	Mus musculus (Mouse)	PR
Q9DB38	Znf580	Zinc finger protein 580	Mus musculus (Mouse)	PR
A7KBS4	Zscan4d	Zinc finger and SCAN domain containing protein 4D	Mus musculus (Mouse)	PR
Q91VW9	Zkscan3	Zinc finger protein with KRAB and SCAN domains 3	Mus musculus (Mouse)	PR
P10925	Zfy1	Zinc finger Y-chromosomal protein 1	Mus musculus (Mouse)	PR
P08046	Egr1	Early growth response protein 1	Mus musculus (Mouse)	PR
Q3TTC2	Yy2	Transcription factor YY2	Mus musculus (Mouse)	PR
Q3UTQ7	Prdm10	PR domain zinc finger protein 10	Mus musculus (Mouse)	PR
Q6P3Y5	Znf280c	Zinc finger protein 280C	Mus musculus (Mouse)	PR
Q9ERU3	Znf22	Zinc finger protein 22	Mus musculus (Mouse)	PR
Q8VIG1	Rest	RE1-silencing transcription factor	Mus musculus (Mouse)	PR
Q9Z1D8	Zkscan5	Zinc finger protein with KRAB and SCAN domains 5	Mus musculus (Mouse)	PR
Q8BID6	Zbtb46	Zinc finger and BTB domain-containing protein 46	Mus musculus (Mouse)	PR
P17012	Zfx	Zinc finger X-chromosomal protein	Mus musculus (Mouse)	PR
Q9WUK6	Zbtb18	Zinc finger and BTB domain-containing protein 18	Mus musculus (Mouse)	PR
O35738	Klf12	Krueppel-like factor 12	Mus musculus (Mouse)	PR
B2RXC5	Znf382	Zinc finger protein 382	Mus musculus (Mouse)	PR
O08900	Ikzf3	Zinc finger protein Aiolos	Mus musculus (Mouse)	PR
Q5DU09	Znf652	Zinc finger protein 652	Mus musculus (Mouse)	PR
Q5RJ54	Zscan26	Zinc finger and SCAN domain-containing protein 26	Mus musculus (Mouse)	PR
Q8BLM0	Klf8	Krueppel-like factor 8	Mus musculus (Mouse)	PR
Q99JB0	Klf7	Krueppel-like factor 7	Mus musculus (Mouse)	PR
Q8R0A2	Zbtb44	Zinc finger and BTB domain-containing protein 44	Mus musculus (Mouse)	PR
P20662	Zfy2	Zinc finger Y-chromosomal protein 2	Mus musculus (Mouse)	PR
Q80VJ6	Zscan4c	Zinc finger and SCAN domain containing protein 4C	Mus musculus (Mouse)	PR
Q3URS2	Zscan4f	Zinc finger and SCAN domain containing protein 4F	Mus musculus (Mouse)	PR
Q60980	Klf3	Krueppel-like factor 3	Mus musculus (Mouse)	PR
Q8K3J5	Znf131	Zinc finger protein 131	Mus musculus (Mouse)	PR
Q9Z2K3	Znf394	Zinc finger protein 394	Rattus norvegicus (Rat)	PR
Q642B9	Znf18	Zinc finger protein 18	Rattus norvegicus (Rat)	PR
B0K011	Osr1	Protein odd-skipped-related 1	Rattus norvegicus (Rat)	PR
D3ZUU2	Gzf1	GDNF-inducible zinc finger protein 1	Rattus norvegicus (Rat)	PR
B1WBU4	Zbtb8a	Zinc finger and BTB domain-containing protein 8A	Rattus norvegicus (Rat)	PR
Q7TNK3	Znf24	Zinc finger protein 24	Rattus norvegicus (Rat)	PR
O35819	Klf6	Krueppel-like factor 6	Rattus norvegicus (Rat)	PR
Q9R1D1	Ctcf	Transcriptional repressor CTCF	Rattus norvegicus (Rat)	PR
P43301	Egr3	Early growth response protein 3	Rattus norvegicus (Rat)	PR
P08154	Egr1	Early growth response protein 1	Rattus norvegicus (Rat)	PR
A0JPL0	Znf382	Zinc finger protein 382	Rattus norvegicus (Rat)	PR
Q4KLI1	Zkscan1	Zinc finger protein with KRAB and SCAN domains 1	Rattus norvegicus (Rat)	PR
A1L1J6	Znf652	Zinc finger protein 652	Rattus norvegicus (Rat)	PR
Q9SHD0	ZAT4	Zinc finger protein ZAT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q0P4X6	zbtb44	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
A4II20	egr1	Early growth response protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q6P882	zbtb8a.2	Zinc finger and BTB domain-containing protein 8A.2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q567C6	znf367	Zinc finger protein 367	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
A7Y7X5	znf711	Zinc finger protein 711	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MERVNDASCG	PSGCYTYQVS	RHSTEMLHNL	NQQRKNGGRF	CDVLLRVGDE	SFPAHRAVLA
70	80	90	100	110	120
ACSEYFESVF	SAQLGDGGAA	DGGPADVGGA	TAAPGGGAGG	SRELEMHTIS	SKVFGDILDF
130	140	150	160	170	180
AYTSRIVVRL	ESFPELMTAA	KFLLMRSVIE	ICQEVIKQSN	VQILVPPARA	DIMLFRPPGT
190	200	210	220	230	240
SDLGFPLDMT	NGAALAANSN	GIAGSMQPEE	EAARAAGAAI	AGQASLPVLP	GVDRLPMVAG
250	260	270	280	290	300
PLSPQLLTSP	FPSVASSAPP	LTGKRGRGRP	RKANLLDSMF	GSPGGLREAG	ILPCGLCGKV
310	320	330	340	350	360
FTDANRLRQH	EAQHGVTSLQ	LGYIDLPPPR	LGENGLPISE	DPDGPRKRSR	TRKQVACEIC
370	380	390	400	410	420
GKIFRDVYHL	NRHKLSHSGE	KPYSCPVCGL	RFKRKDRMSY	HVRSHDGSVG	KPYICQSCGK
430	440	450	460	470	480
GFSRPDHLNG	HIKQVHTSER	PHKCQTCNAS	FATRDRLRSH	LACHEDKVPC	QVCGKYLRAA
490	500	510	520	530	540
YMADHLKKHS	EGPSNFCSIC	NRGFSSASYL	KVHVKTHHGV	PLPQVSRHQE	PILNGGAAFH
550	560	570	580	590	600
CARTYGNKEG	QKCSHQDPIE	SSDSYGDLSD	ASDLKTPEKQ	SANGSFSCDM	AVPKNKMESD
610	620	630	640	650	660
GEKKYPCPEC	GSFFRSKSYL	NKHIQKVHVR	ALGGPLGDLG	PALGSPFSPQ	QNMSLLESFG
670	680
FQIVQSAFAS	SLVDPEVDQQ	PMGPEGK