Q9H2S5
PR
Gene name |
RNF39 (HZFW) |
Protein name |
RING finger protein 39 |
Names |
Protein HZFw |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:80352 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9H2S5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9H2S5-F1 | Predicted | AlphaFoldDB |
724 variants for Q9H2S5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs141667762 CA3694525 |
2 | W>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs749932907 | 2 | W>L | No |
ExAC gnomAD |
|
|
CA3694526 rs141667762 |
2 | W>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs1277670420 | 3 | W>C | No | gnomAD | |
| rs963832883 | 3 | W>R | No | gnomAD | |
|
CA3694524 rs201647756 |
3 | W>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3694522 rs780946687 |
4 | R>S | No |
ClinGen ExAC gnomAD |
|
| rs767004865 | 4 | R>T | No |
ExAC TOPMed gnomAD |
|
|
CA136038629 rs1047338734 |
5 | D>K | No |
ClinGen Ensembl |
|
| rs761660186 | 5 | D>V | No |
ExAC TOPMed gnomAD |
|
| TCGA novel | 5 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs139134806 | 6 | L>F | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA363056794 rs1486309392 |
6 | L>P | No |
ClinGen gnomAD |
|
| rs1464405012 | 6 | L>W | No | gnomAD | |
|
rs540602936 CA136038624 |
7 | T>C | No |
ClinGen 1000Genomes |
|
| rs1170994142 | 7 | T>M | No | gnomAD | |
| rs771405664 | 7 | T>P | No | Ensembl | |
| rs567988738 | 9 | L>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
1000Genomes ExAC gnomAD NCI-TCGA |
|
CA3694520 rs751097397 |
10 | R>P | No |
ClinGen ExAC gnomAD |
|
| rs1420788357 | 11 | L>P | No | gnomAD | |
|
rs758342650 CA363056759 |
12 | W>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs762784854 | 12 | W>R | No |
ExAC gnomAD |
|
|
CA363056753 rs752561825 |
13 | L>H | No |
ClinGen ExAC gnomAD |
|
|
CA3694516 rs752561825 |
13 | L>L | No |
ClinGen ExAC gnomAD |
|
| rs775231867 | 13 | L>M | No |
ExAC gnomAD |
|
| rs1022590479 | 16 | E>D | No |
TOPMed gnomAD |
|
| rs1180477509 | 16 | E>Q | No | gnomAD | |
|
CA363056728 rs1385216323 |
17 | A>P | No |
ClinGen gnomAD |
|
|
rs765085043 CA3694515 |
18 | I>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1360244380 CA363056716 |
19 | P>M | No |
ClinGen gnomAD |
|
| rs1233829119 | 21 | E>Q | No | gnomAD | |
|
rs115871178 CA3694513 |
21 | E>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs975450356 CA136038566 |
21 | E>T | No |
ClinGen Ensembl |
|
| rs1249020464 | 22 | G>R | No | TOPMed | |
|
rs767824578 CA3694512 |
22 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1429132199 CA363056693 |
23 | R>* | No |
ClinGen gnomAD |
|
|
CA363056698 rs1281971383 |
23 | R>R | No |
ClinGen TOPMed |
|
| rs1012634937 | 23 | R>W | No |
TOPMed gnomAD |
|
|
rs762087972 CA3694511 |
24 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs912660448 CA136038553 |
24 | K>W | No |
ClinGen TOPMed gnomAD |
|
|
rs1285001406 CA363056683 |
25 | A>D | No |
ClinGen TOPMed gnomAD |
|
| rs887516187 | 25 | A>E | No |
TOPMed gnomAD |
|
| rs1257466320 | 25 | A>S | No |
TOPMed gnomAD |
|
|
rs987000229 CA136038541 |
25 | A>S | No |
ClinGen TOPMed gnomAD |
|
| rs887516187 | 25 | A>V | No |
TOPMed gnomAD |
|
| rs747201531 | 26 | A>S | No |
ExAC gnomAD |
|
|
TCGA novel CA3694510 rs774595724 |
26 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen ExAC gnomAD |
|
CA3694509 rs768800898 |
26 | A>Y | No |
ClinGen ExAC gnomAD |
|
| rs1348367415 | 29 | N>D | No | TOPMed | |
| rs772126855 | 29 | N>K | No |
ExAC gnomAD |
|
|
rs1311541215 CA363056647 |
31 | G>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 31 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1582404811 | 32 | V>A | No | Ensembl | |
|
rs981299845 CA136038502 |
33 | G>P | No |
ClinGen TOPMed |
|
|
CA363056628 rs1376404052 |
34 | E>E | No |
ClinGen gnomAD |
|
| rs1444262687 | 34 | E>K | No | gnomAD | |
| rs372528926 | 35 | K>N | No |
ESP ExAC TOPMed gnomAD |
|
|
rs1397716133 CA363056623 |
35 | K>Y | No |
ClinGen gnomAD |
|
|
rs971296954 CA136038495 |
36 | G>Q | No |
ClinGen TOPMed |
|
|
rs967277640 CA136038483 |
37 | I>L | No |
ClinGen gnomAD |
|
|
CA363056605 rs1236185279 |
37 | I>Q | No |
ClinGen TOPMed |
|
| rs1165905835 | 39 | T>K | No | gnomAD | |
| rs1432581051 | 40 | A>E | No | TOPMed | |
|
CA363056587 rs1398230189 |
40 | A>G | No |
ClinGen gnomAD |
|
| rs754295949 | 40 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
NCI-TCGA ExAC gnomAD |
|
rs1020613063 CA136038471 |
40 | A>Y | No |
ClinGen gnomAD |
|
| rs780526477 | 41 | S>N | No |
ExAC gnomAD |
|
|
rs746853654 CA3694506 |
42 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs887477602 CA136038468 |
43 | R>S | No |
ClinGen TOPMed |
|
|
CA363056554 rs1462966729 |
45 | G>D | No |
ClinGen TOPMed gnomAD |
|
| rs755745783 | 45 | G>S | No |
ExAC gnomAD |
|
| rs531494342 | 46 | P>Q | No |
1000Genomes ExAC gnomAD |
|
|
rs1332151590 CA363056546 |
47 | P>G | No |
ClinGen TOPMed |
|
|
CA363056544 rs1439082070 |
47 | P>H | No |
ClinGen TOPMed gnomAD |
|
| rs892841089 | 47 | P>L | No | TOPMed | |
|
rs1332151590 CA363056547 |
47 | P>S | No |
ClinGen TOPMed |
|
|
rs1306804072 CA363056534 |
48 | S>C | No |
ClinGen TOPMed |
|
| rs767070867 | 49 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
NCI-TCGA ExAC gnomAD |
|
CA136038444 rs990095171 |
49 | A>W | No |
ClinGen gnomAD |
|
| rs761442939 | 50 | R>P | No |
ExAC gnomAD |
|
|
CA363056516 rs1477603643 |
51 | S>L | No |
ClinGen gnomAD |
|
| TCGA novel | 51 | S>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1188385447 CA363056510 |
52 | K>L | No |
ClinGen gnomAD |
|
| rs1561989248 | 52 | K>M | No | Ensembl | |
| rs866333396 | 52 | K>N | No | Ensembl | |
| rs1214391472 | 53 | A>T | No | gnomAD | |
| rs200295803 | 55 | T>M | No |
1000Genomes ExAC gnomAD |
|
|
CA136038413 rs1001215432 |
55 | T>S | No |
ClinGen TOPMed gnomAD |
|
| rs1163139815 | 55 | T>S | No |
TOPMed gnomAD |
|
|
CA363056487 rs1199756830 |
56 | V>I | No |
ClinGen gnomAD |
|
|
CA363056488 rs1199756830 |
56 | V>S | No |
ClinGen gnomAD |
|
|
rs1340039128 CA363056486 |
57 | V>K | No |
ClinGen gnomAD |
|
|
rs1216320347 CA363056476 |
58 | A>D | No |
ClinGen gnomAD |
|
|
rs770176290 CA3694505 |
58 | A>T | No |
ClinGen ExAC gnomAD |
|
| rs1307412870 | 59 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD NCI-TCGA |
|
CA363056468 rs1316918185 |
59 | E>F | No |
ClinGen gnomAD |
|
|
rs906915243 CA136038405 |
60 | G>A | No |
ClinGen Ensembl |
|
|
CA363056457 rs1246555135 |
61 | A>I | No |
ClinGen TOPMed gnomAD |
|
| rs775281694 | 61 | A>P | No |
ExAC gnomAD |
|
|
CA363056462 rs1340465544 |
61 | A>P | No |
ClinGen Ensembl |
|
| rs375563136 | 62 | A>V | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs773552564 | 63 | S>C | No |
ExAC TOPMed gnomAD |
|
| rs1187015845 | 64 | R>K | No | TOPMed | |
|
CA363056430 rs1392447053 |
65 | S>* | No |
ClinGen gnomAD |
|
| rs772173202 | 65 | S>Y | No |
ExAC gnomAD |
|
|
rs1047288924 TCGA novel CA136038388 |
66 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen TOPMed gnomAD |
|
CA363056424 rs1403143791 |
66 | W>Y | No |
ClinGen gnomAD |
|
| rs779105941 | 67 | L>I | No |
ExAC gnomAD |
|
|
CA363056421 rs1465228302 |
67 | L>S | No |
ClinGen gnomAD |
|
|
rs1165157971 CA363056412 |
68 | S>P | No |
ClinGen gnomAD |
|
|
rs1418670266 CA363056414 |
68 | S>V | No |
ClinGen gnomAD |
|
|
CA136038383 rs868558387 |
69 | M>S | No |
ClinGen Ensembl |
|
| rs201484849 | 69 | M>V | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3694500 rs777266493 |
70 | D>F | No |
ClinGen ExAC gnomAD |
|
| rs141667762 | 70 | D>H | No |
ESP ExAC TOPMed gnomAD |
|
| rs141667762 | 70 | D>N | No |
ESP ExAC TOPMed gnomAD |
|
|
CA3694499 rs558873043 |
71 | A>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| rs201647756 | 71 | A>V | No |
1000Genomes ExAC TOPMed gnomAD |
|
|
rs752193862 CA3694498 |
72 | P>C | No |
ClinGen ExAC gnomAD |
|
| rs780946687 | 72 | P>S | No |
ExAC gnomAD |
|
| rs1047338734 | 73 | E>K | No | Ensembl | |
|
CA3694497 rs765271457 |
74 | L>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1486309392 | 74 | L>P | No | gnomAD | |
| rs540602936 | 75 | G>C | No | 1000Genomes | |
|
rs1196683612 CA363056373 |
75 | G>Q | No |
ClinGen gnomAD |
|
|
CA3694496 rs754844953 |
76 | P>S | No |
ClinGen ExAC gnomAD |
|
| rs751097397 | 78 | L>P | No |
ExAC gnomAD |
|
| rs758342650 | 80 | E>D | No |
ExAC TOPMed gnomAD |
|
|
rs1240277314 CA363056342 |
80 | E>Q | No |
ClinGen gnomAD |
|
|
rs753699803 CA363056343 |
80 | E>W | No |
ClinGen ExAC gnomAD |
|
| rs752561825 | 81 | R>H | No |
ExAC gnomAD |
|
| rs752561825 | 81 | R>L | No |
ExAC gnomAD |
|
|
rs762141311 CA3694494 |
81 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA3694493 rs762141311 |
81 | R>R | No |
ClinGen ExAC gnomAD |
|
|
rs1446711716 CA363056332 |
82 | L>G | No |
ClinGen gnomAD |
|
|
CA363056336 rs1307625673 |
82 | L>T | No |
ClinGen gnomAD |
|
|
rs77391493 CA3694492 |
83 | E>E | No |
ClinGen ExAC gnomAD |
|
|
rs77391493 CA136038343 |
83 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA136038338 rs946689450 |
84 | Q>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA3694491 rs764397171 |
85 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1385216323 | 85 | L>P | No | gnomAD | |
|
rs538878624 CA3694490 |
86 | A>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| rs765085043 | 86 | A>E | No |
ExAC TOPMed gnomAD |
|
|
rs1162429724 CA363056312 |
86 | A>P | No |
ClinGen gnomAD |
|
| rs1360244380 | 87 | T>M | No | gnomAD | |
|
rs942723865 CA136038312 |
89 | P>C | No |
ClinGen Ensembl |
|
| rs115871178 | 89 | P>R | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs975450356 | 89 | P>T | No | Ensembl | |
| rs767824578 | 90 | L>R | No |
ExAC TOPMed gnomAD |
|
| rs1429132199 | 91 | C>* | No | gnomAD | |
| rs1281971383 | 91 | C>R | No | TOPMed | |
|
CA363056276 rs1176652437 |
92 | G>* | No |
ClinGen gnomAD |
|
| rs762087972 | 92 | G>E | No |
ExAC gnomAD |
|
| rs912660448 | 92 | G>W | No |
TOPMed gnomAD |
|
| rs1285001406 | 93 | G>D | No |
TOPMed gnomAD |
|
|
rs749535327 CA136038300 |
93 | G>Q | No |
ClinGen gnomAD |
|
| rs987000229 | 93 | G>S | No |
TOPMed gnomAD |
|
|
CA363056265 rs1439045942 |
94 | S>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA136038280 rs912637131 |
94 | S>R | No |
ClinGen TOPMed |
|
| rs774595724 | 94 | S>T | No |
ExAC gnomAD |
|
| rs768800898 | 94 | S>Y | No |
ExAC gnomAD |
|
|
CA136038265 rs1052918327 |
96 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
CA363056244 rs1288782161 |
97 | D>A | No |
ClinGen gnomAD |
|
|
rs1449497448 CA363056248 |
97 | D>K | No |
ClinGen gnomAD |
|
|
CA363056247 rs1449497448 |
97 | D>Q | No |
ClinGen gnomAD |
|
| rs1311541215 | 99 | V>L | No |
TOPMed gnomAD |
|
|
rs770364540 CA3694487 |
100 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs746308698 CA3694486 |
101 | L>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1372426396 CA363056221 |
101 | L>H | No |
ClinGen gnomAD |
|
| rs981299845 | 101 | L>P | No | TOPMed | |
|
rs746308698 CA363056222 |
101 | L>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1376404052 | 102 | A>E | No | gnomAD | |
|
CA3694484 rs771216014 |
103 | C>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1434488225 CA363056210 |
103 | C>W | No |
ClinGen gnomAD |
|
| rs1397716133 | 103 | C>Y | No | gnomAD | |
| rs971296954 | 104 | E>Q | No | TOPMed | |
| rs967277640 | 105 | H>L | No | gnomAD | |
| rs1236185279 | 105 | H>Q | No | TOPMed | |
|
CA363056193 rs1362178494 |
106 | S>* | No |
ClinGen gnomAD |
|
|
CA136038477 rs1022916676 |
106 | S>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
TOPMed gnomAD ClinGen NCI-TCGA |
|
rs758025828 CA3694481 |
107 | F>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs981234297 CA136038233 |
107 | F>R | No |
ClinGen TOPMed gnomAD |
|
|
rs758025828 CA363056186 |
107 | F>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1398230189 | 108 | C>G | No | gnomAD | |
|
rs1476715144 CA363056184 |
108 | C>R | No |
ClinGen gnomAD |
|
|
CA3694480 rs747738150 |
108 | C>V | No |
ClinGen ExAC gnomAD |
|
| rs1020613063 | 108 | C>Y | No | gnomAD | |
|
rs201745062 CA136038219 |
109 | R>H | No |
ClinGen Ensembl |
|
| rs746853654 | 110 | A>T | No |
ExAC TOPMed gnomAD |
|
|
rs754965997 CA363056168 |
111 | C>A | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs887477602 | 111 | C>S | No | TOPMed | |
|
CA3694478 rs754965997 |
111 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1196566540 CA363056158 |
112 | L>I | No |
ClinGen TOPMed |
|
|
rs1451187882 CA363056163 |
112 | L>P | No |
ClinGen TOPMed |
|
| rs1462966729 | 113 | A>D | No |
TOPMed gnomAD |
|
|
rs1249652665 CA363056149 |
113 | A>I | No |
ClinGen TOPMed |
|
|
CA363056152 rs1216419977 |
113 | A>K | No |
ClinGen gnomAD |
|
|
CA136038201 rs753660371 |
114 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3694477 rs753660371 |
114 | R>S | No |
ClinGen ExAC gnomAD |
|
| rs1332151590 | 115 | R>G | No | TOPMed | |
| rs1439082070 | 115 | R>H | No |
TOPMed gnomAD |
|
| rs1332151590 | 115 | R>S | No | TOPMed | |
| rs1306804072 | 116 | W>C | No | TOPMed | |
|
CA3694476 rs780002534 |
116 | W>P | No |
ClinGen ExAC gnomAD |
|
| rs990095171 | 117 | G>W | No | gnomAD | |
|
CA3694475 rs377243892 |
118 | T>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs1477603643 | 119 | P>L | No | gnomAD | |
|
CA3694474 rs750219698 |
119 | P>R | No |
ClinGen ExAC gnomAD |
|
| rs1188385447 | 120 | P>L | No | gnomAD | |
|
rs764450187 CA3694473 |
120 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs767986875 CA3694461 |
122 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA136037254 CA363055656 rs867006094 |
123 | G>I | No |
ClinGen Ensembl |
|
| rs1001215432 | 123 | G>S | No |
TOPMed gnomAD |
|
| rs1199756830 | 124 | T>I | No | gnomAD | |
|
CA3694460 rs748828127 |
124 | T>K | No |
ClinGen ExAC gnomAD |
|
| rs1199756830 | 124 | T>S | No | gnomAD | |
| rs1340039128 | 125 | E>K | No | gnomAD | |
| rs1216320347 | 126 | A>D | No | gnomAD | |
| rs770176290 | 126 | A>T | No |
ExAC gnomAD |
|
|
CA3694459 rs780187420 |
127 | S>* | No |
ClinGen ExAC gnomAD |
|
|
rs756085027 CA3694458 |
127 | S>* | No |
ClinGen ExAC TOPMed |
|
| rs1316918185 | 127 | S>F | No | gnomAD | |
|
CA136037242 rs1042141910 |
127 | S>R | No |
ClinGen TOPMed |
|
| rs906915243 | 128 | P>A | No | Ensembl | |
|
CA3694457 rs370999065 |
129 | T>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs1246555135 | 129 | T>I | No |
TOPMed gnomAD |
|
| rs1340465544 | 129 | T>P | No | Ensembl | |
|
CA363055587 rs781084466 |
129 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694456 rs781084466 |
129 | T>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1458077833 CA363055530 |
130 | A>L | No |
ClinGen gnomAD |
|
|
TCGA novel CA3694436 rs781135384 |
130 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen ExAC gnomAD |
| rs1392447053 | 133 | C>* | No | gnomAD | |
|
CA363055492 rs1163113633 |
133 | C>L | No |
ClinGen gnomAD |
|
| rs1047288924 | 134 | C>* | No |
TOPMed gnomAD |
|
|
rs757062595 CA3694434 |
134 | C>I | No |
ClinGen ExAC gnomAD |
|
| rs1403143791 | 134 | C>Y | No | gnomAD | |
|
rs2074479 CA363055478 |
135 | G>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs2074479 CA3694433 |
135 | G>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1465228302 | 135 | G>S | No | gnomAD | |
| rs1165157971 | 136 | L>P | No | gnomAD | |
| rs1418670266 | 136 | L>V | No | gnomAD | |
| rs868558387 | 137 | P>S | No | Ensembl | |
| rs777266493 | 138 | C>F | No |
ExAC gnomAD |
|
|
CA363055445 rs1180994911 |
138 | C>P | No |
ClinGen gnomAD |
|
|
CA3694432 rs779049891 |
139 | P>K | No |
ClinGen ExAC gnomAD |
|
| rs558873043 | 139 | P>S | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs752193862 | 140 | R>C | No |
ExAC gnomAD |
|
|
rs755198768 CA3694431 |
142 | S>G | No |
ClinGen ExAC gnomAD |
|
| rs765271457 | 142 | S>N | No |
ExAC TOPMed gnomAD |
|
|
rs753952630 CA363055380 |
143 | L>H | No |
ClinGen ExAC gnomAD |
|
|
rs753952630 CA3694430 |
143 | L>N | No |
ClinGen ExAC gnomAD |
|
| rs1196683612 | 143 | L>Q | No | gnomAD | |
|
CA3694429 rs766400479 |
144 | R>F | No |
ClinGen ExAC gnomAD |
|
|
CA3694428 rs756631873 |
144 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs754844953 | 144 | R>S | No |
ExAC gnomAD |
|
|
CA363055351 rs1337100991 |
145 | S>L | No |
ClinGen TOPMed |
|
|
CA3694427 rs750863703 |
145 | S>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694425 rs377456133 |
147 | V>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1353865256 CA363056348 |
147 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD ClinGen NCI-TCGA |
|
CA136037012 rs377456133 |
147 | V>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1260970723 | 148 | R>* | No | gnomAD | |
|
rs374504156 CA3694422 |
148 | R>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs763683980 CA3694423 |
148 | R>H | No |
ClinGen ExAC gnomAD |
|
| rs1240277314 | 148 | R>Q | No | gnomAD | |
| rs753699803 | 148 | R>W | No |
ExAC gnomAD |
|
| rs762141311 | 149 | L>Q | No |
ExAC gnomAD |
|
| rs762141311 | 149 | L>R | No |
ExAC gnomAD |
|
| rs1446711716 | 150 | A>G | No | gnomAD | |
| rs1307625673 | 150 | A>T | No | gnomAD | |
| rs77391493 | 151 | V>E | No |
ExAC gnomAD |
|
| rs77391493 | 151 | V>G | No |
ExAC gnomAD |
|
|
CA3694421 rs375274560 |
151 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs946689450 | 152 | E>Q | No |
TOPMed gnomAD |
|
| rs764397171 | 153 | V>M | No |
ExAC TOPMed gnomAD |
|
| rs538878624 | 154 | R>* | No |
1000Genomes ExAC TOPMed gnomAD |
|
|
CA3694419 rs769358974 |
154 | R>I | No |
ClinGen ExAC gnomAD |
|
| rs1162429724 | 154 | R>P | No | gnomAD | |
|
CA363055241 rs1348724213 |
154 | R>T | No |
ClinGen TOPMed |
|
|
rs1361526154 CA363055230 |
155 | I>F | No |
ClinGen gnomAD |
|
|
rs1278532356 CA363055223 |
156 | S>Y | No |
ClinGen TOPMed |
|
| rs942723865 | 157 | R>C | No | Ensembl | |
|
rs1418384302 CA363055207 |
157 | R>G | No |
ClinGen gnomAD |
|
|
CA363055181 rs1205014116 |
159 | L>R | No |
ClinGen TOPMed |
|
| rs1176652437 | 160 | R>* | No | gnomAD | |
|
rs1232073323 CA363055174 |
160 | R>P | No |
ClinGen TOPMed |
|
| TCGA novel | 161 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs981571704 CA136036142 |
161 | E>N | No |
ClinGen Ensembl |
|
| rs749535327 | 161 | E>Q | No | gnomAD | |
|
rs1173621880 CA363054656 |
162 | K>P | No |
ClinGen gnomAD |
|
| rs1439045942 | 162 | K>Q | No |
TOPMed gnomAD |
|
| rs912637131 | 162 | K>R | No | TOPMed | |
| rs1052918327 | 164 | A>V | No |
TOPMed gnomAD |
|
| rs1288782161 | 165 | E>A | No | gnomAD | |
| rs1449497448 | 165 | E>K | No | gnomAD | |
| rs1449497448 | 165 | E>Q | No | gnomAD | |
|
rs1475519468 CA363054634 |
166 | P>A | No |
ClinGen TOPMed |
|
| rs770364540 | 168 | A>V | No |
ExAC gnomAD |
|
| rs746308698 | 169 | R>G | No |
ExAC TOPMed gnomAD |
|
| rs1372426396 | 169 | R>H | No | gnomAD | |
| rs746308698 | 169 | R>S | No |
ExAC TOPMed gnomAD |
|
|
CA136036122 rs372233460 |
169 | R>T | No |
ClinGen ESP gnomAD |
|
| rs771216014 | 171 | G>E | No |
ExAC TOPMed gnomAD |
|
| rs1434488225 | 171 | G>W | No | gnomAD | |
|
CA136036120 rs962217611 |
172 | R>L | No |
ClinGen TOPMed |
|
|
rs1191788222 CA363054589 |
173 | R>R | No |
ClinGen gnomAD |
|
| rs1362178494 | 174 | R>* | No | gnomAD | |
|
rs1487150697 CA363054585 |
174 | R>H | No |
ClinGen TOPMed gnomAD |
|
| rs758025828 | 175 | G>A | No |
ExAC TOPMed gnomAD |
|
|
CA136036119 rs1015115621 |
175 | G>F | No |
ClinGen Ensembl |
|
| rs981234297 | 175 | G>R | No |
TOPMed gnomAD |
|
| rs758025828 | 175 | G>V | No |
ExAC TOPMed gnomAD |
|
| rs1476715144 | 176 | G>R | No | gnomAD | |
| rs747738150 | 176 | G>V | No |
ExAC gnomAD |
|
| rs201745062 | 177 | R>H | No | Ensembl | |
|
CA3694401 rs2301752 |
177 | R>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs909569391 CA363054564 |
178 | I>H | No |
ClinGen TOPMed gnomAD |
|
|
rs909569391 CA363054565 |
178 | I>N | No |
ClinGen TOPMed gnomAD |
|
|
CA136036103 rs909569391 |
178 | I>Y | No |
ClinGen TOPMed gnomAD |
|
| rs754965997 | 179 | P>A | No |
ExAC TOPMed gnomAD |
|
|
CA363054557 rs1222432784 |
179 | P>G | No |
ClinGen TOPMed gnomAD |
|
| rs754965997 | 179 | P>S | No |
ExAC TOPMed gnomAD |
|
|
CA136036102 rs982486887 |
180 | T>C | No |
ClinGen TOPMed gnomAD |
|
| rs1196566540 | 180 | T>I | No | TOPMed | |
| rs1451187882 | 180 | T>P | No | TOPMed | |
| rs1249652665 | 181 | M>I | No | TOPMed | |
| rs1216419977 | 181 | M>K | No | gnomAD | |
|
rs1326175460 CA363054544 |
181 | M>N | No |
ClinGen gnomAD |
|
|
rs1216436797 CA363054547 |
181 | M>R | No |
ClinGen gnomAD |
|
| rs753660371 | 182 | G>C | No |
ExAC gnomAD |
|
|
CA3694399 CA363054539 rs776173276 |
182 | G>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs753660371 | 182 | G>S | No |
ExAC gnomAD |
|
|
CA363054527 rs1355546468 |
184 | L>M | No |
ClinGen TOPMed |
|
| rs780002534 | 184 | L>P | No |
ExAC gnomAD |
|
|
CA363054524 rs1285720529 |
184 | L>P | No |
ClinGen TOPMed |
|
|
CA363054523 rs1285720529 |
184 | L>R | No |
ClinGen TOPMed |
|
|
CA3694398 rs770807766 |
185 | D>D | No |
ClinGen ExAC gnomAD |
|
| rs377243892 | 186 | L>P | No |
ESP ExAC TOPMed gnomAD |
|
|
CA363054517 rs1336162105 |
186 | L>T | No |
ClinGen gnomAD |
|
| rs750219698 | 187 | P>R | No |
ExAC gnomAD |
|
| rs764450187 | 188 | G>R | No |
ExAC gnomAD |
|
|
rs746919022 CA3694397 |
188 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA363054495 rs1425886109 |
189 | E>M | No |
ClinGen gnomAD |
|
| TCGA novel | 190 | D>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs767986875 | 190 | D>N | No |
ExAC TOPMed gnomAD |
|
|
rs1168727639 CA363054492 |
190 | D>S | No |
ClinGen gnomAD |
|
| rs867006094 | 191 | M>I | No | Ensembl | |
|
rs772899896 CA3694396 |
191 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694394 rs61754472 |
192 | R>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA363054480 rs1425469785 |
192 | R>H | No |
ClinGen gnomAD |
|
| rs748828127 | 192 | R>K | No |
ExAC gnomAD |
|
|
CA363054483 rs61754472 |
192 | R>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA363054475 rs1254077754 |
193 | K>H | No |
ClinGen gnomAD |
|
|
CA136036088 rs964583031 |
194 | T>E | No |
ClinGen TOPMed |
|
| rs756085027 | 195 | W>* | No |
ExAC TOPMed |
|
| rs780187420 | 195 | W>* | No |
ExAC gnomAD |
|
|
CA3694393 rs11753382 |
195 | W>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1042141910 | 195 | W>R | No | TOPMed | |
| rs370999065 | 197 | R>* | No |
ESP ExAC TOPMed gnomAD |
|
| rs781084466 | 197 | R>P | No |
ExAC TOPMed gnomAD |
|
| rs781084466 | 197 | R>Q | No |
ExAC TOPMed gnomAD |
|
|
rs1259466938 CA363054451 |
197 | R>R | No |
ClinGen TOPMed gnomAD |
|
|
rs769983175 CA3694392 |
198 | F>H | No |
ClinGen ExAC |
|
| rs1458077833 | 198 | F>L | No | gnomAD | |
| rs781135384 | 198 | F>S | No |
ExAC gnomAD |
|
|
CA3694391 rs1057539 |
200 | V>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA363054433 rs1057539 |
200 | V>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1163113633 | 201 | P>L | No | gnomAD | |
| rs757062595 | 202 | T>I | No |
ExAC gnomAD |
|
| rs2074479 | 203 | S>A | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs2074479 VAR_022723 |
203 | S>P | No |
1000Genomes ESP ExAC TOPMed gnomAD UniProt dbSNP |
|
| rs2074479 | 203 | S>S | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA136036077 rs1040517177 |
203 | S>T | No |
ClinGen gnomAD |
|
|
CA136036066 rs571062694 |
205 | S>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs571062694 CA3694389 |
205 | S>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| rs1180994911 | 206 | S>P | No | gnomAD | |
|
CA363054389 rs1448191573 |
207 | N>D | No |
ClinGen gnomAD |
|
| rs779049891 | 207 | N>K | No |
ExAC gnomAD |
|
|
CA363054392 rs1416456789 |
207 | N>R | No |
ClinGen TOPMed |
|
|
rs1227404831 CA363054383 |
208 | S>E | No |
ClinGen gnomAD |
|
|
CA363054386 rs1313117800 |
208 | S>T | No |
ClinGen TOPMed |
|
|
CA363054376 rs1402495112 |
209 | E>R | No |
ClinGen gnomAD |
|
| rs755198768 | 210 | D>G | No |
ExAC gnomAD |
|
| rs753952630 | 211 | D>H | No |
ExAC gnomAD |
|
| rs753952630 | 211 | D>N | No |
ExAC gnomAD |
|
|
CA363054355 rs1409582667 |
212 | L>E | No |
ClinGen gnomAD |
|
| rs766400479 | 212 | L>F | No |
ExAC gnomAD |
|
| rs756631873 | 212 | L>P | No |
ExAC TOPMed gnomAD |
|
|
CA363054356 rs1329436569 |
212 | L>W | No |
ClinGen gnomAD |
|
| rs1337100991 | 213 | P>L | No | TOPMed | |
| rs750863703 | 213 | P>S | No |
ExAC TOPMed gnomAD |
|
|
CA363054351 rs1242542797 |
213 | P>T | No |
ClinGen TOPMed |
|
|
rs778134042 CA3694386 |
214 | E>R | No |
ClinGen ExAC gnomAD |
|
|
CA363054346 rs778134042 |
214 | E>S | No |
ClinGen ExAC gnomAD |
|
| rs377456133 | 215 | D>H | No |
ExAC TOPMed gnomAD |
|
| rs377456133 | 215 | D>Y | No |
ExAC TOPMed gnomAD |
|
| rs1260970723 | 216 | Y>* | No | gnomAD | |
| rs374504156 | 216 | Y>F | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs763683980 | 216 | Y>H | No |
ExAC gnomAD |
|
|
rs758887756 CA3694385 |
217 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA363054325 rs1440283711 |
217 | P>Y | No |
ClinGen gnomAD |
|
| rs375274560 | 219 | V>I | No |
ESP ExAC TOPMed gnomAD |
|
|
rs1239446812 CA363054311 |
219 | V>K | No |
ClinGen gnomAD |
|
|
CA363054303 rs1176308626 |
220 | K>M | No |
ClinGen gnomAD |
|
| rs769358974 | 222 | M>I | No |
ExAC gnomAD |
|
| rs754826025 | 222 | M>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA363054289 rs1436860209 |
222 | M>P | No |
ClinGen gnomAD |
|
| rs1348724213 | 222 | M>T | No | TOPMed | |
| rs1361526154 | 223 | L>F | No | gnomAD | |
| TCGA novel | 223 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1010227717 CA136036040 |
223 | L>V | No |
ClinGen TOPMed gnomAD |
|
| rs1278532356 | 224 | H>Y | No | TOPMed | |
| rs1418384302 | 225 | R>G | No | gnomAD | |
|
rs765018847 CA3694383 |
225 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA136036026 rs1003366347 |
226 | L>S | No |
ClinGen TOPMed |
|
|
rs1291537691 CA363054258 |
227 | T>F | No |
ClinGen TOPMed gnomAD |
|
| rs1205014116 | 227 | T>R | No | TOPMed | |
| rs1232073323 | 228 | A>P | No | TOPMed | |
|
rs1241464673 CA363054247 |
229 | D>G | No |
ClinGen TOPMed gnomAD |
|
| rs981571704 | 229 | D>N | No | Ensembl | |
| rs1173621880 | 230 | L>P | No | gnomAD | |
|
CA136036019 rs528186943 |
230 | L>V | No |
ClinGen 1000Genomes TOPMed |
|
|
rs1441650291 CA363054221 |
233 | D>R | No |
ClinGen gnomAD |
|
| rs1475519468 | 234 | P>A | No | TOPMed | |
|
CA3694380 rs2301753 |
236 | T>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1393819127 CA363054194 |
237 | A>N | No |
ClinGen gnomAD |
|
| rs372233460 | 237 | A>T | No |
ESP gnomAD |
|
|
CA363054186 rs1385343361 |
238 | H>N | No |
ClinGen gnomAD |
|
|
CA363054175 rs1378738932 |
239 | R>G | No |
ClinGen TOPMed |
|
|
CA363054178 rs916490850 |
239 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
rs916490850 CA136036000 |
239 | R>Q | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 240 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA363054171 rs1420219395 |
240 | R>K | No |
ClinGen gnomAD |
|
| rs962217611 | 240 | R>L | No | TOPMed | |
| rs1191788222 | 241 | L>R | No | gnomAD | |
| rs1487150697 | 242 | L>H | No |
TOPMed gnomAD |
|
|
CA363054152 rs1387953744 |
242 | L>R | No |
ClinGen Ensembl |
|
|
CA363054153 rs1382171859 |
242 | L>Y | No |
ClinGen gnomAD |
|
|
rs1156751932 CA363054143 |
243 | I>C | No |
ClinGen gnomAD |
|
| rs1015115621 | 243 | I>F | No | Ensembl | |
|
rs1469135007 CA363054138 |
244 | S>T | No |
ClinGen TOPMed gnomAD |
|
| rs2301752 | 245 | A>A | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_022724 rs2301752 |
245 | A>T | No |
1000Genomes ESP ExAC TOPMed gnomAD UniProt dbSNP |
|
|
rs1331620721 CA363054124 |
246 | D>D | No |
ClinGen gnomAD |
|
| rs909569391 | 246 | D>H | No |
TOPMed gnomAD |
|
| rs909569391 | 246 | D>N | No |
TOPMed gnomAD |
|
|
rs528904872 CA136035985 |
246 | D>S | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
| rs909569391 | 246 | D>Y | No |
TOPMed gnomAD |
|
| rs1222432784 | 247 | R>G | No |
TOPMed gnomAD |
|
| rs982486887 | 248 | R>C | No |
TOPMed gnomAD |
|
|
CA363054549 rs1279636328 |
248 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
gnomAD ClinGen NCI-TCGA |
|
CA363054108 rs1268594413 |
249 | S>A | No |
ClinGen gnomAD |
|
| rs1326175460 | 249 | S>N | No | gnomAD | |
| rs1216436797 | 249 | S>R | No | gnomAD | |
|
CA136035966 rs773266930 |
249 | S>W | No |
ClinGen ExAC gnomAD |
|
|
CA3694400 rs776173276 |
250 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
|
rs1356456758 CA363054106 |
250 | V>K | No |
ClinGen gnomAD |
|
| rs776173276 | 250 | V>L | No |
ExAC TOPMed gnomAD |
|
|
rs771984650 CA3694376 |
250 | V>V | No |
ClinGen ExAC gnomAD |
|
| rs1355546468 | 252 | L>M | No | TOPMed | |
| rs1285720529 | 252 | L>P | No | TOPMed | |
| rs1285720529 | 252 | L>R | No | TOPMed | |
| rs770807766 | 253 | A>D | No |
ExAC gnomAD |
|
|
rs1345760192 CA363054077 |
254 | P>C | No |
ClinGen gnomAD |
|
|
rs1445455887 CA363054074 |
254 | P>L | No |
ClinGen TOPMed |
|
|
rs1445455887 CA363054075 |
254 | P>P | No |
ClinGen TOPMed |
|
| rs1336162105 | 254 | P>T | No | gnomAD | |
|
CA363054071 rs1276727867 |
255 | P>* | No |
ClinGen gnomAD |
|
|
rs774104086 CA3694374 |
256 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs746919022 | 256 | G>R | No |
ExAC gnomAD |
|
|
CA363054053 rs746043640 |
257 | T>* | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1425886109 | 257 | T>M | No | gnomAD | |
|
rs376524967 CA363053610 |
258 | P>G | No |
ClinGen ESP TOPMed gnomAD |
|
| rs1168727639 | 258 | P>S | No | gnomAD | |
|
rs376524967 CA136035651 |
258 | P>V | No |
ClinGen ESP TOPMed gnomAD |
|
| rs772899896 | 259 | A>T | No |
ExAC TOPMed gnomAD |
|
| rs61754472 | 260 | P>A | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1238839228 CA363053593 |
260 | P>C | No |
ClinGen gnomAD |
|
| rs1425469785 | 260 | P>H | No | gnomAD | |
| rs61754472 | 260 | P>T | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1254077754 | 261 | P>H | No | gnomAD | |
|
rs764001778 CA3694336 |
261 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs964583031 | 262 | D>E | No | TOPMed | |
|
rs1358193765 CA363053569 |
262 | D>P | No |
ClinGen TOPMed gnomAD |
|
| rs11753382 | 263 | G>C | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1169664996 CA363054020 |
263 | G>T | No |
ClinGen gnomAD |
|
|
rs1487524808 CA363053553 |
264 | P>K | No |
ClinGen TOPMed |
|
|
CA136035621 rs867373109 |
265 | K>H | No |
ClinGen gnomAD |
|
| rs1259466938 | 265 | K>R | No |
TOPMed gnomAD |
|
| rs769983175 | 266 | R>H | No | ExAC | |
|
CA363054002 rs1479243129 |
266 | R>M | No |
ClinGen gnomAD |
|
| rs1057539 | 268 | D>D | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1057539 VAR_022725 |
268 | D>N | No |
1000Genomes ESP ExAC TOPMed gnomAD UniProt dbSNP |
|
| rs1057539 | 268 | D>Y | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs758940176 CA3694365 |
269 | Q>M | No |
ClinGen ExAC gnomAD |
|
|
rs9261293 CA3694364 |
270 | L>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1040517177 | 271 | P>T | No | gnomAD | |
|
rs779373840 CA3694363 |
273 | V>C | No |
ClinGen ExAC |
|
| rs571062694 | 273 | V>L | No |
1000Genomes ExAC gnomAD |
|
| rs571062694 | 273 | V>M | No |
1000Genomes ExAC gnomAD |
|
|
rs1191236977 CA363053435 |
273 | V>Y | No |
ClinGen TOPMed |
|
| rs1448191573 | 275 | G>D | No | gnomAD | |
|
CA363053403 rs1297200720 |
275 | G>R | No |
ClinGen TOPMed gnomAD |
|
| rs1416456789 | 275 | G>R | No | TOPMed | |
| rs1227404831 | 276 | A>E | No | gnomAD | |
|
rs769025458 CA3694327 |
276 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1313117800 | 276 | A>T | No | TOPMed | |
| rs1402495112 | 277 | Q>R | No | gnomAD | |
|
CA363053382 rs1351956716 |
277 | Q>V | No |
ClinGen gnomAD |
|
|
rs753467188 CA3694360 |
278 | G>T | No |
ClinGen ExAC gnomAD |
|
|
CA3694359 rs765948440 |
278 | G>V | No |
ClinGen ExAC |
|
|
CA363053915 rs1279013564 |
280 | G>A | No |
ClinGen gnomAD |
|
| rs1409582667 | 280 | G>E | No | gnomAD | |
|
rs1220722903 CA363053911 |
280 | G>M | No |
ClinGen gnomAD |
|
| rs1329436569 | 280 | G>W | No | gnomAD | |
| rs1242542797 | 281 | A>T | No | TOPMed | |
|
rs1177060062 CA363053899 |
282 | G>L | No |
ClinGen TOPMed |
|
|
CA3694322 rs369294101 CA3694323 |
282 | G>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| rs778134042 | 282 | G>R | No |
ExAC gnomAD |
|
|
rs1177060062 CA363053900 |
282 | G>R | No |
ClinGen TOPMed |
|
| rs778134042 | 282 | G>S | No |
ExAC gnomAD |
|
|
rs577656142 CA3694321 |
283 | R>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA136035825 rs922357572 |
283 | R>K | No |
ClinGen TOPMed |
|
|
rs577656142 CA363053324 |
283 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs749879814 CA363053882 |
285 | C>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749879814 CA3694357 |
285 | C>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs533103241 CA136035822 |
285 | C>P | No |
ClinGen 1000Genomes |
|
| rs758887756 | 285 | C>R | No |
ExAC gnomAD |
|
| rs1440283711 | 285 | C>Y | No | gnomAD | |
| rs1239446812 | 287 | E>K | No | gnomAD | |
|
CA363053273 rs1220065265 |
287 | E>S | No |
ClinGen gnomAD |
|
|
rs1242540383 CA363053875 |
287 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1229428218 CA363053267 |
287 | E>W | No |
ClinGen TOPMed |
|
| rs1176308626 | 288 | V>M | No | gnomAD | |
|
CA363053866 rs1179559226 |
288 | V>V | No |
ClinGen TOPMed gnomAD |
|
|
CA363053862 rs1429905652 |
289 | E>A | No |
ClinGen gnomAD |
|
| rs1436860209 | 290 | T>P | No | gnomAD | |
|
rs761687873 CA3694355 |
291 | A>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs200705517 CA3694354 |
291 | A>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs761687873 CA3694356 |
291 | A>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1010227717 | 291 | A>V | No |
TOPMed gnomAD |
|
|
CA363053848 rs540860670 |
292 | D>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3694351 rs776965364 |
292 | D>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 292 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs540860670 CA3694352 |
292 | D>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs911397745 CA136035789 |
293 | A>L | No |
ClinGen TOPMed gnomAD |
|
| rs765018847 | 293 | A>P | No |
ExAC TOPMed gnomAD |
|
|
rs911397745 CA363053841 |
293 | A>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs765018847 CA136036029 |
293 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ExAC TOPMed gnomAD ClinGen NCI-TCGA |
| rs1003366347 | 294 | A>S | No | TOPMed | |
| rs1291537691 | 295 | S>F | No |
TOPMed gnomAD |
|
|
rs747150346 CA3694349 |
296 | C>S | No |
ClinGen ExAC gnomAD |
|
| rs1241464673 | 297 | R>G | No |
TOPMed gnomAD |
|
|
CA363053813 rs773383627 |
298 | D>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694348 rs773383627 |
298 | D>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs528186943 | 298 | D>V | No |
1000Genomes TOPMed |
|
| rs1441650291 | 301 | G>R | No | gnomAD | |
|
rs1191830405 CA363053782 |
303 | D>G | No |
ClinGen TOPMed |
|
|
rs1191830405 CA363053784 |
303 | D>R | No |
ClinGen TOPMed |
|
|
rs1200722313 CA363053773 |
304 | A>* | No |
ClinGen TOPMed gnomAD |
|
| rs2301753 | 304 | A>A | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1561979924 CA363053770 |
304 | A>A | No |
ClinGen Ensembl |
|
| rs1325710504 | 304 | A>D | No | gnomAD | |
|
VAR_022726 rs2301753 |
304 | A>E | No |
1000Genomes ESP ExAC TOPMed gnomAD UniProt dbSNP |
|
|
rs139005614 CA3694346 |
305 | D>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1393819127 | 305 | D>N | No | gnomAD | |
|
CA3694345 rs779425781 |
305 | D>P | No |
ClinGen ExAC gnomAD |
|
|
rs139005614 CA363053767 |
305 | D>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1385343361 | 306 | D>N | No | gnomAD | |
| rs1378738932 | 307 | E>G | No | TOPMed | |
|
CA363053755 rs1561979878 |
307 | E>H | No |
ClinGen Ensembl |
|
| rs916490850 | 307 | E>K | No |
TOPMed gnomAD |
|
| rs916490850 | 307 | E>Q | No |
TOPMed gnomAD |
|
| rs1420219395 | 308 | E>K | No | gnomAD | |
|
CA363053751 rs1379625838 |
308 | E>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1379625838 CA363053752 |
308 | E>M | No |
ClinGen TOPMed gnomAD |
|
|
rs996183104 CA136035731 |
309 | S>T | No |
ClinGen Ensembl |
|
| rs1387953744 | 310 | H>R | No | Ensembl | |
| rs1382171859 | 310 | H>Y | No | gnomAD | |
| rs1156751932 | 311 | Y>C | No | gnomAD | |
|
CA363053724 rs1464851220 |
312 | A>H | No |
ClinGen TOPMed |
|
| rs1469135007 | 312 | A>T | No |
TOPMed gnomAD |
|
|
CA363053723 rs1464851220 |
312 | A>Y | No |
ClinGen TOPMed |
|
|
CA363053713 rs1396583723 |
313 | V>D | No |
ClinGen TOPMed |
|
|
rs370735380 CA3694343 |
313 | V>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs1331620721 | 314 | G>D | No | gnomAD | |
| rs528904872 | 314 | G>S | No |
1000Genomes TOPMed gnomAD |
|
|
rs755694474 CA136035677 |
316 | A>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694341 rs755694474 |
316 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA136035660 rs904988206 |
317 | G>A | No |
ClinGen TOPMed |
|
| rs1268594413 | 317 | G>A | No | gnomAD | |
|
rs773266930 CA3694377 |
317 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ExAC gnomAD ClinGen NCI-TCGA |
| rs773266930 | 317 | G>W | No |
ExAC gnomAD |
|
| rs1356456758 | 318 | E>K | No | gnomAD | |
| rs771984650 | 318 | E>V | No |
ExAC gnomAD |
|
| rs1345760192 | 322 | R>C | No | gnomAD | |
| rs1445455887 | 322 | R>L | No | TOPMed | |
|
CA3694338 rs762180592 |
322 | R>L | No |
ClinGen ExAC gnomAD |
|
| rs1445455887 | 322 | R>P | No | TOPMed | |
| rs1276727867 | 323 | K>* | No | gnomAD | |
| rs774104086 | 324 | G>D | No |
ExAC TOPMed gnomAD |
|
| rs746043640 | 325 | C>* | No |
ExAC TOPMed gnomAD |
|
| rs376524967 | 326 | V>G | No |
ESP TOPMed gnomAD |
|
| rs376524967 | 326 | V>V | No |
ESP TOPMed gnomAD |
|
| TCGA novel | 327 | R>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1238839228 | 328 | L>C | No | gnomAD | |
| rs764001778 | 329 | C>H | No |
ExAC TOPMed gnomAD |
|
| rs1358193765 | 330 | P>P | No |
TOPMed gnomAD |
|
| rs1169664996 | 331 | A>T | No | gnomAD | |
| rs1487524808 | 332 | G>K | No | TOPMed | |
|
rs775421418 CA3694332 |
332 | G>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3694333 rs775116335 |
332 | G>V | No |
ClinGen ExAC gnomAD |
|
| rs142632327 | 333 | A>C | No |
ESP gnomAD |
|
| rs867373109 | 333 | A>H | No | gnomAD | |
|
CA3694331 rs760758281 |
334 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1479243129 | 334 | V>M | No | gnomAD | |
| rs775421418 | 334 | V>N | No |
ExAC TOPMed gnomAD |
|
| rs775116335 | 334 | V>V | No |
ExAC gnomAD |
|
| rs760758281 | 336 | A>L | No |
ExAC TOPMed gnomAD |
|
| rs758940176 | 337 | V>M | No |
ExAC gnomAD |
|
| rs9261293 | 338 | E>G | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA363053438 rs1370560257 |
339 | G>G | No |
ClinGen gnomAD |
|
| rs779373840 | 341 | G>C | No | ExAC | |
| rs1370560257 | 341 | G>G | No | gnomAD | |
|
rs1297200720 CA363053401 |
341 | G>L | No |
ClinGen TOPMed gnomAD |
|
| rs1191236977 | 341 | G>Y | No | TOPMed | |
|
rs769025458 CA3694326 |
342 | G>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA363053399 rs1424300465 |
342 | G>S | No |
ClinGen TOPMed |
|
| TCGA novel | 343 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1297200720 | 343 | R>L | No |
TOPMed gnomAD |
|
| rs1297200720 | 343 | R>R | No |
TOPMed gnomAD |
|
| rs769025458 | 344 | L>H | No |
ExAC TOPMed gnomAD |
|
|
rs556846834 CA3694325 |
344 | L>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| rs769025458 | 344 | L>P | No |
ExAC TOPMed gnomAD |
|
| rs1424300465 | 344 | L>S | No | TOPMed | |
| rs1351956716 | 345 | W>V | No | gnomAD | |
|
rs1424565295 CA363053357 |
346 | A>C | No |
ClinGen gnomAD |
|
| rs556846834 | 346 | A>L | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs753467188 | 346 | A>T | No |
ExAC gnomAD |
|
| rs765948440 | 346 | A>V | No | ExAC | |
| rs1279013564 | 348 | T>A | No | gnomAD | |
| rs1424565295 | 348 | T>C | No | gnomAD | |
| rs1220722903 | 348 | T>M | No | gnomAD | |
|
rs1191949930 CA363053322 |
349 | A>L | No |
ClinGen gnomAD |
|
| rs369294101 | 350 | P>L | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1177060062 | 350 | P>L | No | TOPMed | |
| rs1177060062 | 350 | P>R | No | TOPMed | |
|
rs1399854541 CA363053318 |
350 | P>T | No |
ClinGen TOPMed |
|
| rs577656142 | 351 | E>A | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs922357572 | 351 | E>K | No | TOPMed | |
|
rs751046519 CA3694319 |
351 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1191949930 | 351 | E>L | No | gnomAD | |
| rs577656142 | 351 | E>S | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1399854541 | 352 | P>T | No | TOPMed | |
| rs749879814 | 353 | T>I | No |
ExAC TOPMed gnomAD |
|
| rs751046519 | 353 | T>K | No |
ExAC TOPMed gnomAD |
|
| rs749879814 | 353 | T>N | No |
ExAC TOPMed gnomAD |
|
| rs533103241 | 353 | T>P | No | 1000Genomes | |
| rs1220065265 | 355 | L>S | No | gnomAD | |
| rs1242540383 | 355 | L>V | No |
TOPMed gnomAD |
|
| rs1229428218 | 355 | L>W | No | TOPMed | |
| rs1179559226 | 356 | G>V | No |
TOPMed gnomAD |
|
| rs1429905652 | 357 | G>A | No | gnomAD | |
| rs761687873 | 359 | E>* | No |
ExAC TOPMed gnomAD |
|
| rs200705517 | 359 | E>G | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs761687873 | 359 | E>Q | No |
ExAC TOPMed gnomAD |
|
| rs540860670 | 360 | P>A | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs776965364 | 360 | P>L | No |
ExAC gnomAD |
|
| rs540860670 | 360 | P>T | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs911397745 | 361 | P>L | No |
TOPMed gnomAD |
|
| rs911397745 | 361 | P>Q | No |
TOPMed gnomAD |
|
| TCGA novel | 364 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs747150346 | 364 | R>S | No |
ExAC gnomAD |
|
| TCGA novel | 366 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs773383627 | 366 | R>H | No |
ExAC TOPMed gnomAD |
|
| rs773383627 | 366 | R>L | No |
ExAC TOPMed gnomAD |
|
| TCGA novel | 367 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1191830405 | 371 | W>G | No | TOPMed | |
| rs1191830405 | 371 | W>R | No | TOPMed | |
| rs1200722313 | 372 | E>* | No |
TOPMed gnomAD |
|
| rs1561979924 | 372 | E>A | No | Ensembl | |
| rs139005614 | 373 | R>G | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs779425781 | 373 | R>P | No |
ExAC gnomAD |
|
| rs139005614 | 373 | R>W | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1561979878 | 375 | R>H | No | Ensembl | |
| rs1379625838 | 376 | V>L | No |
TOPMed gnomAD |
|
| rs1379625838 | 376 | V>M | No |
TOPMed gnomAD |
|
| rs996183104 | 377 | A>T | No | Ensembl | |
| rs1464851220 | 380 | D>H | No | TOPMed | |
| rs1464851220 | 380 | D>Y | No | TOPMed | |
| rs1396583723 | 381 | G>D | No | TOPMed | |
| rs370735380 | 381 | G>S | No |
ESP ExAC TOPMed gnomAD |
|
| rs755694474 | 384 | L>F | No |
ExAC TOPMed gnomAD |
|
| rs755694474 | 384 | L>V | No |
ExAC TOPMed gnomAD |
|
| rs904988206 | 385 | D>A | No | TOPMed | |
| rs762180592 | 390 | F>L | No |
ExAC gnomAD |
|
| rs376524967 | 392 | A>G | No |
ESP TOPMed gnomAD |
|
| rs376524967 | 392 | A>V | No |
ESP TOPMed gnomAD |
|
| rs1238839228 | 394 | G>C | No | gnomAD | |
| rs764001778 | 395 | P>H | No |
ExAC TOPMed gnomAD |
|
| rs1358193765 | 396 | L>P | No |
TOPMed gnomAD |
|
| rs1487524808 | 398 | E>K | No | TOPMed | |
|
CA136035632 rs142632327 |
399 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ESP gnomAD ClinGen NCI-TCGA |
| rs867373109 | 399 | R>H | No | gnomAD | |
| rs775421418 | 400 | I>N | No |
ExAC TOPMed gnomAD |
|
| rs775116335 | 400 | I>V | No |
ExAC gnomAD |
|
| rs760758281 | 402 | P>L | No |
ExAC TOPMed gnomAD |
|
| rs1370560257 | 407 | C>G | No | gnomAD | |
| rs1191236977 | 407 | C>Y | No | TOPMed | |
| rs1297200720 | 409 | P>L | No |
TOPMed gnomAD |
|
| rs1297200720 | 409 | P>R | No |
TOPMed gnomAD |
|
| rs769025458 | 410 | R>H | No |
ExAC TOPMed gnomAD |
|
| rs769025458 | 410 | R>P | No |
ExAC TOPMed gnomAD |
|
| rs1424300465 | 410 | R>S | No | TOPMed | |
| rs1351956716 | 411 | A>V | No | gnomAD | |
| rs556846834 | 412 | P>L | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1424565295 | 414 | R>C | No | gnomAD | |
| rs369294101 | 416 | V>L | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs577656142 | 417 | P>A | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1191949930 | 417 | P>L | No | gnomAD | |
| rs577656142 | 417 | P>S | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1399854541 | 418 | A>T | No | TOPMed | |
| rs751046519 | 419 | E>K | No |
ExAC TOPMed gnomAD |
|
| rs1220065265 | 421 | S>S | No | gnomAD | |
| rs1229428218 | 421 | S>W | No | TOPMed |
No associated diseases with Q9H2S5
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
| regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
49 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5E9G4 | TRIM10 | Tripartite motif-containing protein 10 | Bos taurus (Bovine) | PR |
| Q2T9Z0 | TRIM17 | E3 ubiquitin-protein ligase TRIM17 | Bos taurus (Bovine) | PR |
| E1BJS7 | TRIM71 | E3 ubiquitin-protein ligase TRIM71 | Bos taurus (Bovine) | PR |
| Q7YRV4 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 | Bos taurus (Bovine) | PR |
| Q1PRL4 | TRIM71 | E3 ubiquitin-protein ligase TRIM71 | Gallus gallus (Chicken) | PR |
| Q7YR32 | TRIM10 | Tripartite motif-containing protein 10 | Pan troglodytes (Chimpanzee) | PR |
| Q9BTV5 | FSD1 | Fibronectin type III and SPRY domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q9UJV3 | MID2 | Probable E3 ubiquitin-protein ligase MID2 | Homo sapiens (Human) | PR |
| P29590 | PML | Protein PML | Homo sapiens (Human) | PR |
| Q9NQ86 | TRIM36 | E3 ubiquitin-protein ligase TRIM36 | Homo sapiens (Human) | PR |
| Q86UV6 | TRIM74 | Tripartite motif-containing protein 74 | Homo sapiens (Human) | PR |
| Q2Q1W2 | TRIM71 | E3 ubiquitin-protein ligase TRIM71 | Homo sapiens (Human) | PR |
| Q9BXM9 | FSD1L | FSD1-like protein | Homo sapiens (Human) | PR |
| Q5EBN2 | TRIM61 | Putative tripartite motif-containing protein 61 | Homo sapiens (Human) | PR |
| Q86UV7 | TRIM73 | Tripartite motif-containing protein 73 | Homo sapiens (Human) | PR |
| Q86XT4 | TRIM50 | E3 ubiquitin-protein ligase TRIM50 | Homo sapiens (Human) | PR |
| Q8N9V2 | TRIML1 | Probable E3 ubiquitin-protein ligase TRIML1 | Homo sapiens (Human) | PR |
| Q9BZY9 | TRIM31 | E3 ubiquitin-protein ligase TRIM31 | Homo sapiens (Human) | PR |
| Q6ZMU5 | TRIM72 | Tripartite motif-containing protein 72 | Homo sapiens (Human) | PR |
| Q9UPQ4 | TRIM35 | E3 ubiquitin-protein ligase TRIM35 | Homo sapiens (Human) | PR |
| Q9C029 | TRIM7 | E3 ubiquitin-protein ligase TRIM7 | Homo sapiens (Human) | PR |
| O15553 | MEFV | Pyrin | Homo sapiens (Human) | SS |
| A6NCK2 | TRIM43B | Tripartite motif-containing protein 43B | Homo sapiens (Human) | PR |
| P19474 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 | Homo sapiens (Human) | PR |
| Q14142 | TRIM14 | Tripartite motif-containing protein 14 | Homo sapiens (Human) | PR |
| A6NK02 | TRIM75 | Tripartite motif-containing protein 75 | Homo sapiens (Human) | PR |
| Q9WUH5 | Trim10 | Tripartite motif-containing protein 10 | Mus musculus (Mouse) | PR |
| Q8BZT2 | Sh3rf2 | E3 ubiquitin-protein ligase SH3RF2 | Mus musculus (Mouse) | PR |
| Q7TPM3 | Trim17 | E3 ubiquitin-protein ligase TRIM17 | Mus musculus (Mouse) | PR |
| Q1XH17 | Trim72 | Tripartite motif-containing protein 72 | Mus musculus (Mouse) | PR |
| Q60953 | Pml | Protein PML | Mus musculus (Mouse) | PR |
| Q9JJ26 | Mefv | Pyrin | Mus musculus (Mouse) | SS |
| Q99PQ1 | Trim12a | Tripartite motif-containing protein 12A | Mus musculus (Mouse) | PR |
| Q61510 | Trim25 | E3 ubiquitin/ISG15 ligase TRIM25 | Mus musculus (Mouse) | PR |
| Q810I2 | Trim50 | E3 ubiquitin-protein ligase TRIM50 | Mus musculus (Mouse) | PR |
| Q1PSW8 | Trim71 | E3 ubiquitin-protein ligase TRIM71 | Mus musculus (Mouse) | PR |
| Q3TL54 | Trim43a | Tripartite motif-containing protein 43A | Mus musculus (Mouse) | PR |
| P86449 | Trim43c | Tripartite motif-containing protein 43C | Mus musculus (Mouse) | PR |
| O77666 | TRIM26 | Tripartite motif-containing protein 26 | Sus scrofa (Pig) | PR |
| O19085 | TRIM10 | Tripartite motif-containing protein 10 | Sus scrofa (Pig) | PR |
| Q865W2 | TRIM50 | E3 ubiquitin-protein ligase TRIM50 | Sus scrofa (Pig) | PR |
| Q9JJ25 | Mefv | Pyrin | Rattus norvegicus (Rat) | SS |
| A0JPQ4 | Trim72 | Tripartite motif-containing protein 72 | Rattus norvegicus (Rat) | PR |
| Q810I1 | Trim50 | E3 ubiquitin-protein ligase TRIM50 | Rattus norvegicus (Rat) | PR |
| D3ZVM4 | Trim71 | E3 ubiquitin-protein ligase TRIM71 | Rattus norvegicus (Rat) | PR |
| Q920M2 | Rnf39 | RING finger protein 39 | Rattus norvegicus (Rat) | PR |
| F6QEU4 | trim71 | E3 ubiquitin-protein ligase TRIM71 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q640S6 | trim72 | Tripartite motif-containing protein 72 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| E7FAM5 | trim71 | E3 ubiquitin-protein ligase TRIM71 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWWRDLTRLR | LWLKREAIPG | EGRKAAKVNA | GVGEKGIYTA | SSRGGPPSAR | SKAVTVVAEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AASRSWLSMD | APELGPGLVE | RLEQLATCPL | CGGSFEDPVL | LACEHSFCRA | CLARRWGTPP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ATGTEASPTA | CPCCGLPCPR | RSLRSNVRLA | VEVRISRELR | EKLAEPGARA | GRRRGGRIPT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MGCLDLPGED | MRKTWRRFEV | PTSKSSNSED | DLPEDYPVVK | KMLHRLTADL | TLDPGTAHRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLISADRRSV | QLAPPGTPAP | PDGPKRFDQL | PAVLGAQGFG | AGRHCWEVET | ADAASCRDSS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GEDADDEESH | YAVGAAGESV | QRKGCVRLCP | AGAVWAVEGR | GGRLWALTAP | EPTLLGGVEP |
| 370 | 380 | 390 | 400 | 410 | |
| PPRRIRVDLD | WERGRVAFYD | GRSLDLLYAF | QAPGPLGERI | FPLFCTCDPR | APLRIVPAES |