Q9FZ92
Gene name |
RH44 (At1g28180, F3H9.16) |
Protein name |
Putative DEAD-box ATP-dependent RNA helicase 44 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
|
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FZ92
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FZ92-F1 | Predicted | AlphaFoldDB |
No variants for Q9FZ92
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9FZ92 | |||||
No associated diseases with Q9FZ92
4 regional properties for Q9FZ92
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 365 - 373 | IPR000629 |
| domain | Helicase, C-terminal | 456 - 606 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 238 - 422 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 229 - 448 | IPR014001 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| catalytic step 2 spliceosome | A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P23394 | PRP28 | Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9Y6V7 | DDX49 | Probable ATP-dependent RNA helicase DDX49 | Homo sapiens (Human) | PR |
| Q4FZF3 | Ddx49 | Probable ATP-dependent RNA helicase DDX49 | Mus musculus (Mouse) | PR |
| Q9C718 | RH20 | DEAD-box ATP-dependent RNA helicase 20 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84W89 | RH37 | DEAD-box ATP-dependent RNA helicase 37 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q8H136 | RH14 | DEAD-box ATP-dependent RNA helicase 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94A52 | EIF4A3 | Eukaryotic initiation factor 4A-III homolog | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LA13 | RH11 | DEAD-box ATP-dependent RNA helicase 11 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9M2F9 | RH52 | DEAD-box ATP-dependent RNA helicase 52 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q56XG6 | RH15 | DEAD-box ATP-dependent RNA helicase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3E9C3 | RH58 | DEAD-box ATP-dependent RNA helicase 58, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W4R3 | RH30 | DEAD-box ATP-dependent RNA helicase 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZG7 | RH38 | DEAD-box ATP-dependent RNA helicase 38 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFN6 | RH56 | DEAD-box ATP-dependent RNA helicase 56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZB4 | RH43 | Putative DEAD-box ATP-dependent RNA helicase 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LU46 | RH35 | DEAD-box ATP-dependent RNA helicase 35 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKQSFEGFMK | TAMEKKTLDF | DNLTKPVFLT | KAHRKELALK | RCQDEIADRD | RRSIVQISRS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NSDNDDGNRP | RDVKRERHRS | HDHDRNRESD | REFREREVKA | RVEKLEMVKR | EKEINAMKEQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YLGTTKPKKR | VIMKPSKNFR | FDWENTEDTL | SGEMNVLYQN | PHEAQPLFGR | GCRAGIDRRE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QKKLMTGKHE | REKREEEDKH | WSEKKLEEMN | ERDWRIFKED | FNISYRGSKI | PHPMRNWEET |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IPLGLEQRDV | IGISATGSGK | TAAFVLPMLA | YISRLPPMRE | ENQTEGPYAL | VMVPTRELAH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QIEEETVKFS | RYLGFKAVSI | TGWESIEKQA | LKLSQGCEIV | IATPGRLLDC | LERRYVVLNQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CNYLVLDEAD | RMIDMDFEPQ | VSEVLDVMPC | SNLKPEKEDE | ELEEKKIYRT | TYMFSATMLL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SVERLARKFL | RNPVVVTIGE | TTKFITQQVI | MTKESDKFSR | LKKLIDDLGD | DKTAIVFVNT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RNKVDYIVKN | LEKVGRCRVT | TLHAGKSQEQ | RDYSLEEFKK | KRFNVLVTTD | VLGRGLDILD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LAQVINYDMP | NTMDLYTHRI | GRTGRAGKTG | VATTFLTLED | KDVFYGLKQK | LNECNSLVPP |
| 610 | 620 | ||||
| ELARHEASKF | KPGTFPDRFS | HF |