Q9FMR5
Gene name |
VAMP714 |
Protein name |
Vesicle-associated membrane protein 714 |
Names |
AtVAMP714 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G22360 |
EC number |
|
Protein Class |
|
Descriptions
(Annotation based on sequence homology with P51809)
VAMP7 is involved in the targeting and/or fusion of transport vesicles to their target membrane. Longin domain negatively regulates the ability of VAMP7 like other SNARE attachment proteins including Ykt6.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FMR5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FMR5-F1 | Predicted | AlphaFoldDB |
10 variants for Q9FMR5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_7405650_G_T | 2 | A>E | No | 1000Genomes | |
| ENSVATH07010955 | 2 | A>T | No | 1000Genomes | |
| ENSVATH07010954 | 4 | V>F | No | 1000Genomes | |
| tmp_5_7405639_C_A | 6 | A>S | No | 1000Genomes | |
| ENSVATH10917689 | 44 | R>I | No | 1000Genomes | |
| tmp_5_7405301_C_T | 83 | E>K | No | 1000Genomes | |
| ENSVATH10917687 | 85 | H>L | No | 1000Genomes | |
| ENSVATH07010950 | 135 | V>I | No | 1000Genomes | |
| tmp_5_7404810_C_A | 190 | K>N | No | 1000Genomes | |
| tmp_5_7404417_A_C | 210 | F>V | No | 1000Genomes |
No associated diseases with Q9FMR5
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q12255 | NYV1 | Vacuolar v-SNARE NYV1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q17QI5 | VAMP7 | Vesicle-associated membrane protein 7 | Bos taurus (Bovine) | SS |
| Q5ZL74 | VAMP7 | Vesicle-associated membrane protein 7 | Gallus gallus (Chicken) | SS |
| P51809 | VAMP7 | Vesicle-associated membrane protein 7 | Homo sapiens (Human) | EV |
| P70280 | Vamp7 | Vesicle-associated membrane protein 7 | Mus musculus (Mouse) | SS |
| Q9JHW5 | Vamp7 | Vesicle-associated membrane protein 7 | Rattus norvegicus (Rat) | SS |
| O49377 | VAMP711 | Vesicle-associated membrane protein 711 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9LFP1 | VAMP713 | Vesicle-associated membrane protein 713 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9M376 | VAMP727 | Vesicle-associated membrane protein 727 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9SIQ9 | VAMP712 | Vesicle-associated membrane protein 712 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIVYAVVAR | GTVVLAEFSA | VTGNTGAVVR | RILEKLSPEI | SDERLCFSQD | RYIFHILRSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GLTFLCMAND | TFGRRVPFSY | LEEIHMRFMK | NYGKVAHNAP | AYAMNDEFSR | VLHQQMEFFS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SNPSVDTLNR | VRGEVSEIRS | VMVENIEKIM | ERGDRIELLV | DKTATMQDSS | FHFRKQSKRL |
| 190 | 200 | 210 | 220 | ||
| RRALWMKNAK | LLVLLTCLIV | FLLYIIIASF | CGGITLPSCR | S |