Q9FJD6
PR
Gene name |
RBOHH (At5g60010, MMN10.18) |
Protein name |
Putative respiratory burst oxidase homolog protein H |
Names |
NADPH oxidase RBOHH, AtRBOHH |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G60010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FJD6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FJD6-F1 | Predicted | AlphaFoldDB |
53 variants for Q9FJD6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_24160469_C_T | 5 | T>I | No | 1000Genomes | |
| tmp_5_24160482_T_G | 9 | D>E | No | 1000Genomes | |
| tmp_5_24160507_G_A | 18 | V>I | No | 1000Genomes | |
| ENSVATH07453467 | 26 | S>G | No | 1000Genomes | |
| ENSVATH14641752 | 26 | S>N | No | 1000Genomes | |
| ENSVATH14641753 | 63 | N>K | No | 1000Genomes | |
| tmp_5_24160736_C_T | 94 | P>L | No | 1000Genomes | |
| ENSVATH07453472 | 95 | Q>P | No | 1000Genomes | |
| ENSVATH07453473 | 118 | V>D | No | 1000Genomes | |
| ENSVATH12869290 | 136 | F>I | No | 1000Genomes | |
| tmp_5_24161470_C_T | 216 | T>M | No | 1000Genomes | |
| tmp_5_24161542_C_T | 240 | A>V | No | 1000Genomes | |
| tmp_5_24161548_C_T | 242 | A>V | No | 1000Genomes | |
| tmp_5_24161570_A_T | 249 | E>D | No | 1000Genomes | |
| tmp_5_24161750_C_G | 275 | A>G | No | 1000Genomes | |
| tmp_5_24161764_A_C | 280 | M>L | No | 1000Genomes | |
| tmp_5_24161816_C_T | 297 | T>M | No | 1000Genomes | |
| tmp_5_24161865_T_G | 313 | N>K | No | 1000Genomes | |
| tmp_5_24161867_G_C | 314 | W>S | No | 1000Genomes | |
| tmp_5_24161884_C_T | 320 | L>F | No | 1000Genomes | |
| ENSVATH07453483 | 326 | I>V | No | 1000Genomes | |
| ENSVATH07453484 | 330 | L>I | No | 1000Genomes | |
| tmp_5_24161962_A_G | 346 | I>V | No | 1000Genomes | |
| ENSVATH12869319 | 349 | R>H | No | 1000Genomes | |
| ENSVATH12869320 | 353 | A>V | No | 1000Genomes | |
| ENSVATH03456464 | 357 | A>T | No | 1000Genomes | |
| tmp_5_24162013_C_T | 363 | L>F | No | 1000Genomes | |
| tmp_5_24162110_T_C | 395 | I>T | No | 1000Genomes | |
| ENSVATH14641763 | 419 | C>F | No | 1000Genomes | |
| ENSVATH14641763 | 419 | C>Y | No | 1000Genomes | |
| ENSVATH12869322 | 439 | A>V | No | 1000Genomes | |
| ENSVATH07453486 | 491 | L>F | No | 1000Genomes | |
| tmp_5_24162628_T_C | 535 | V>A | No | 1000Genomes | |
| ENSVATH00744130 | 558 | N>I | No | 1000Genomes | |
| ENSVATH00744131 | 583 | K>T | No | 1000Genomes | |
| tmp_5_24163013_G_C | 591 | K>N | No | 1000Genomes | |
| ENSVATH00744133 | 594 | D>N | No | 1000Genomes | |
| tmp_5_24163162_G_T | 612 | D>Y | No | 1000Genomes | |
| tmp_5_24163364_G_T | 637 | E>D | No | 1000Genomes | |
| tmp_5_24163375_C_T | 641 | A>V | No | 1000Genomes | |
| tmp_5_24163425_G_A | 658 | A>T | No | 1000Genomes | |
| ENSVATH07453501 | 659 | G>D | No | 1000Genomes | |
| ENSVATH00744137 | 675 | F>I | No | 1000Genomes | |
| ENSVATH14641768 | 675 | F>S | No | 1000Genomes | |
| tmp_5_24163859_G_A | 731 | V>I | No | 1000Genomes | |
| ENSVATH14641771 | 742 | S>N | No | 1000Genomes | |
| tmp_5_24163904_G_A | 746 | G>S | No | 1000Genomes | |
| ENSVATH00744139 | 747 | K>M | No | 1000Genomes | |
| tmp_5_24163929_A_T | 754 | Y>F | No | 1000Genomes | |
| tmp_5_24164010_C_G | 781 | T>S | No | 1000Genomes | |
| tmp_5_24164145_A_T | 785 | E>D | No | 1000Genomes | |
| tmp_5_24164147_T_C | 786 | M>T | No | 1000Genomes | |
| tmp_5_24164456_A_G | 825 | I>M | No | 1000Genomes |
No associated diseases with Q9FJD6
7 regional properties for Q9FJD6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | EF-hand domain | 199 - 230 | IPR002048 |
| domain | FAD-binding 8 | 556 - 683 | IPR013112 |
| domain | Ferric reductase, NAD binding domain | 690 - 869 | IPR013121 |
| domain | Ferric reductase transmembrane component-like domain | 356 - 512 | IPR013130 |
| domain | NADPH oxidase Respiratory burst | 96 - 197 | IPR013623 |
| domain | FAD-binding domain, ferredoxin reductase-type | 552 - 686 | IPR017927 |
| binding_site | EF-Hand 1, calcium-binding site | 208 - 220 | IPR018247 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| ferric-chelate reductase activity | Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor. |
| NAD(P)H oxidase H2O2-forming activity | Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. |
| peroxidase activity | Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96PH1 | NOX5 | NADPH oxidase 5 | Homo sapiens (Human) | EV |
| Q948U0 | RBOHA | Respiratory burst oxidase homolog protein A | Solanum tuberosum (Potato) | PR |
| Q948T9 | RBOHB | Respiratory burst oxidase homolog protein B | Solanum tuberosum (Potato) | PR |
| Q5ZAJ0 | RBOHB | Respiratory burst oxidase homolog protein B | Oryza sativa subsp japonica (Rice) | PR |
| O48538 | RBOHF | Respiratory burst oxidase homolog protein F | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P92949 | CDC5 | Ferric reduction oxidase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W110 | FRO4 | Ferric reduction oxidase 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FIJ0 | RBOHD | Respiratory burst oxidase homolog protein D | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SUT8 | RBOHI | Probable respiratory burst oxidase homolog protein I | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4I4K7 | FRO3 | Ferric reduction oxidase 3, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81211 | RBOHE | Respiratory burst oxidase homolog protein E | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKSNTPTEDS | TKWMLESVEI | DSMGESSSKE | PEINLNKNEG | GLKKNASRNL | GVGSIIRTLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSNWRKSGNL | GSPSTRKSGN | LGPPTNAVPK | KTGPQRVERT | TSSAARGLQS | LRFLDRTVTG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RERDAWRSIE | NRFNQFSVDG | KLPKEKFGVC | IGMGDTMEFA | AEVYEALGRR | RQIETENGID |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEQLKLFWED | MIKKDLDCRL | QIFFDMCDKN | GDGKLTEEEV | KEVIVLSASA | NRLGNLKKNA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAYASLIMEE | LDPDHKGYIE | MWQLEILLTG | MVTNADTEKM | KKSQTLTRAM | IPERYRTPMS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KYVSVTAELM | HENWKKLWVL | ALWAIINVYL | FMWKYEEFMR | NPLYNITGRC | VCAAKGAAET |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LKLNMALILV | PVCRKTLTIL | RSTFLNRVVP | FDDNINFHKV | IAYMIAFQAL | LHTALHIFCN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YPRLSSCSYD | VFLTYAGAAL | GNTQPSYLGL | MLTSVSITGV | LMIFFMGFSF | TLAMHYFRRN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IVKLPKPFNV | LAGFNAFWYA | HHLLVLAYIL | LIIHGYYLII | EKPWYQKTTW | MYLAVPMLFY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ASERLFSRLL | QEHSHRVNVI | KAIVYSGNVL | ALYVTKPPGF | KYKSGMYMFV | KCPDLSKFEW |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HPFSITSAPG | DDYLSVHIRA | LGDWTTELRS | RFAKTCEPTQ | AAAKPKPNSL | MRMETRAAGV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NPHIEESQVL | FPKIFIKGPY | GAPAQNYQKF | DILLLVGLGI | GATPFISILK | DMLNHLKPGI |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PRSGQKYEGS | VGGESIGGDS | VSGGGGKKFP | QRAYFFWVTR | EQASFDWFKG | VMDDIAEYDK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| THVIEMHNYL | TSMYEAGDAR | SALIAMVQKL | QHAKNGVDIV | SESRIRTHFA | RPNWRKVFSE |
| 850 | 860 | 870 | 880 | ||
| LSSKHEACRI | GVFYCGSPTL | VRPLKELCQE | FSLESSTRFT | FHKENF |