Q9FJB5

PR
Gene name
RPP8L3 (At5g35450, K21B8.10, MOK9.3)
Protein name
Disease resistance RPP8-like protein 3
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G35450
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-182 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FJB5

Entry ID Method Resolution Chain Position Source
AF-Q9FJB5-F1 Predicted AlphaFoldDB

240 variants for Q9FJB5

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03238521 2 A>S No 1000Genomes
ENSVATH03238522 3 E>D No 1000Genomes
ENSVATH03238523 5 V>F No 1000Genomes
tmp_5_13667833_G_A 9 G>R No 1000Genomes
tmp_5_13667850_G_C 14 W>C No 1000Genomes
ENSVATH08513752 15 A>E No 1000Genomes
tmp_5_13667861_A_G 18 N>S No 1000Genomes
ENSVATH03238526 31 V>L No 1000Genomes
ENSVATH03238527 40 G>R No 1000Genomes
ENSVATH03238535 88 G>E No 1000Genomes
ENSVATH03238536 91 V>I No 1000Genomes
ENSVATH03238537 93 N>K No 1000Genomes
ENSVATH07206307 103 T>R No 1000Genomes
ENSVATH11923908 112 I>V No 1000Genomes
ENSVATH07206311 116 T>S No 1000Genomes
ENSVATH03238539 121 K>E No 1000Genomes
tmp_5_13668179_G_C 124 G>A No 1000Genomes
ENSVATH08513766 125 E>G No 1000Genomes
ENSVATH11923909 126 M>V No 1000Genomes
ENSVATH07206314 129 L>F No 1000Genomes
tmp_5_13668203_A_T 132 Q>L No 1000Genomes
tmp_5_13668216_T_G 136 I>M No 1000Genomes
ENSVATH08513769 139 G>D No 1000Genomes
ENSVATH07206315 141 S>L No 1000Genomes
tmp_5_13668233_T_G 142 L>R No 1000Genomes
ENSVATH07206316 146 D>E No 1000Genomes
ENSVATH07206317 147 I>R No 1000Genomes
ENSVATH08513774 155 F>Y No 1000Genomes
ENSVATH08513775 157 N>D No 1000Genomes
ENSVATH07206318 170 V>L No 1000Genomes
tmp_5_13668320_A_C 171 E>A No 1000Genomes
ENSVATH07206319 171 E>K No 1000Genomes
ENSVATH03238543 172 E>G No 1000Genomes
tmp_5_13668327_G_T 173 L>F No 1000Genomes
tmp_5_13668331_G_T 175 G>C No 1000Genomes
ENSVATH07206320 176 P>H No 1000Genomes
ENSVATH03238544 177 M>I No 1000Genomes
ENSVATH07206321 177 M>L No 1000Genomes
ENSVATH00673232 180 I>N No 1000Genomes
tmp_5_13668353_A_T 182 N>I No 1000Genomes
tmp_5_13668352_A_T 182 N>Y No 1000Genomes
ENSVATH03238545 189 S>A No 1000Genomes
ENSVATH14513479 190 G>V No 1000Genomes
ENSVATH03238547 194 I>M No 1000Genomes
ENSVATH03238550 203 I>V No 1000Genomes
ENSVATH09503858 208 L>F No 1000Genomes
ENSVATH07206322 208 L>I No 1000Genomes
ENSVATH09503857 208 L>S No 1000Genomes
ENSVATH03238552 209 V>A No 1000Genomes
tmp_5_13668462_G_A 218 W>* No 1000Genomes
ENSVATH03238560 230 V>I No 1000Genomes
ENSVATH03238563 239 R>Q No 1000Genomes
ENSVATH00673233 243 G>D No 1000Genomes
ENSVATH07206323 244 E>D No 1000Genomes
ENSVATH03238564 254 Q>H No 1000Genomes
ENSVATH00673234 262 E>D No 1000Genomes
ENSVATH03238569 264 G>A No 1000Genomes
ENSVATH03238572 276 E>K No 1000Genomes
ENSVATH03238573 281 R>L No 1000Genomes
ENSVATH03238573 281 R>Q No 1000Genomes
ENSVATH03238574 284 E>A No 1000Genomes
ENSVATH11923972 305 L>I No 1000Genomes
tmp_5_13668819_T_G 312 L>V No 1000Genomes
ENSVATH03238584 313 S>P No 1000Genomes
ENSVATH03238584 313 S>T No 1000Genomes
tmp_5_13668825_T_A 314 F>I No 1000Genomes
ENSVATH07206328 316 A>P No 1000Genomes
tmp_5_13668839_C_G 318 I>M No 1000Genomes
tmp_5_13668844_A_G 320 N>S No 1000Genomes
ENSVATH08513785 322 K>E No 1000Genomes
ENSVATH08513786 328 F>C No 1000Genomes
ENSVATH08513790 336 N>D No 1000Genomes
tmp_5_13668895_A_G 337 E>G No 1000Genomes
ENSVATH03238587 346 I>M No 1000Genomes
ENSVATH11924015 372 H>L No 1000Genomes
ENSVATH07206333 375 S>R No 1000Genomes
ENSVATH03238594 396 D>N No 1000Genomes
tmp_5_13669189_C_T 404 R>* No 1000Genomes
ENSVATH03238595 405 I>V No 1000Genomes
tmp_5_13669219_C_T 414 P>S No 1000Genomes
ENSVATH08513804 416 D>G No 1000Genomes
ENSVATH03238597 416 D>H No 1000Genomes
ENSVATH14513483 418 K>N No 1000Genomes
tmp_5_13669242_C_A 421 F>L No 1000Genomes
ENSVATH03238602 434 K>N No 1000Genomes
ENSVATH03238601 434 K>Q No 1000Genomes
ENSVATH03238603 439 Y>F No 1000Genomes
ENSVATH03238604 440 S>N No 1000Genomes
ENSVATH03238607 451 L>S No 1000Genomes
ENSVATH07206337 459 D>E No 1000Genomes
ENSVATH03238610 463 E>D No 1000Genomes
ENSVATH07206338 465 V>M No 1000Genomes
ENSVATH11924024 471 I>F No 1000Genomes
ENSVATH07206339 472 A>P No 1000Genomes
ENSVATH08513806 473 E>D No 1000Genomes
ENSVATH07206341 475 S>N No 1000Genomes
ENSVATH07206342 476 N>S No 1000Genomes
ENSVATH08513808 476 N>Y No 1000Genomes
ENSVATH08513810 479 W>* No 1000Genomes
ENSVATH08513810 479 W>S No 1000Genomes
tmp_5_13669420_C_T 481 L>F No 1000Genomes
tmp_5_13669423_A_G 482 K>E No 1000Genomes
tmp_5_13669426_C_T 483 L>F No 1000Genomes
ENSVATH11924035 486 M>L No 1000Genomes
ENSVATH07206343 495 I>L No 1000Genomes
ENSVATH03238612 500 V>E No 1000Genomes
tmp_5_13669501_A_G 508 K>E No 1000Genomes
tmp_5_13669504_G_T 509 V>F No 1000Genomes
ENSVATH07206345 512 S>F No 1000Genomes
ENSVATH03238614 517 I>N No 1000Genomes
ENSVATH07206346 522 S>I No 1000Genomes
ENSVATH07206347 529 V>L No 1000Genomes
ENSVATH11924037 530 H>Q No 1000Genomes
ENSVATH07206351 539 G>E No 1000Genomes
ENSVATH07206353 558 I>M No 1000Genomes
ENSVATH09503893 563 R>C No 1000Genomes
ENSVATH14513497 570 L>I No 1000Genomes
ENSVATH00673237 577 S>L No 1000Genomes
ENSVATH14513500 583 G>W No 1000Genomes
tmp_5_13669747_G_A 590 G>R No 1000Genomes
ENSVATH08513823 597 F>Y No 1000Genomes
tmp_5_13669774_A_T 599 S>C No 1000Genomes
ENSVATH07206355 599 S>R No 1000Genomes
tmp_5_13669781_A_T,G 601 H>L No 1000Genomes
tmp_5_13669781_A_T,G 601 H>R No 1000Genomes
ENSVATH14513501 601 H>Y No 1000Genomes
ENSVATH07206356 602 Q>* No 1000Genomes
ENSVATH07206356 602 Q>E No 1000Genomes
ENSVATH08513824 602 Q>H No 1000Genomes
ENSVATH07206356 602 Q>K No 1000Genomes
tmp_5_13669784_A_G 602 Q>R No 1000Genomes
ENSVATH07206357 604 V>G No 1000Genomes
tmp_5_13669793_T_C 605 V>A No 1000Genomes
ENSVATH03238621 610 S>F No 1000Genomes
ENSVATH03238622 612 I>M No 1000Genomes
tmp_5_13669816_C_T 613 R>W No 1000Genomes
ENSVATH03238624 618 M>L No 1000Genomes
ENSVATH11924040 622 N>D No 1000Genomes
ENSVATH03238625 624 H>D No 1000Genomes
ENSVATH03238625 624 H>N No 1000Genomes
tmp_5_13669850_A_C,G 624 H>P No 1000Genomes
tmp_5_13669850_A_C,G 624 H>R No 1000Genomes
tmp_5_13669856_C_A 626 A>D No 1000Genomes
tmp_5_13669859_T_A 627 I>N No 1000Genomes
tmp_5_13669862_G_A 628 G>E No 1000Genomes
tmp_5_13669861_G_A 628 G>R No 1000Genomes
tmp_5_13669865_T_A 629 V>E No 1000Genomes
tmp_5_13669868_C_T 630 P>L No 1000Genomes
tmp_5_13669867_C_T 630 P>S No 1000Genomes
ENSVATH08513825 631 V>I No 1000Genomes
ENSVATH11924041 634 P>S No 1000Genomes
ENSVATH03238629 641 L>I No 1000Genomes
tmp_5_13669903_G_C 642 E>Q No 1000Genomes
ENSVATH03238630 646 L>I No 1000Genomes
ENSVATH03238632 647 S>C No 1000Genomes
ENSVATH03238632 647 S>F No 1000Genomes
ENSVATH03238631 647 S>P No 1000Genomes
ENSVATH03238633 650 L>Q No 1000Genomes
ENSVATH07206362 650 L>V No 1000Genomes
ENSVATH11924044 651 D>E No 1000Genomes
ENSVATH03238635 651 D>G No 1000Genomes
ENSVATH03238634 651 D>H No 1000Genomes
ENSVATH03238634 651 D>N No 1000Genomes
ENSVATH03238635 651 D>V No 1000Genomes
ENSVATH11924075 653 H>D No 1000Genomes
ENSVATH11924076 653 H>R No 1000Genomes
tmp_5_13669946_C_T 656 T>I No 1000Genomes
ENSVATH07206364 657 K>R No 1000Genomes
ENSVATH03238639 659 E>K No 1000Genomes
ENSVATH07206365 668 Y>F No 1000Genomes
ENSVATH03238640 668 Y>H No 1000Genomes
ENSVATH11924077 670 W>C No 1000Genomes
ENSVATH08513826 670 W>L No 1000Genomes
ENSVATH03238641 671 C>G No 1000Genomes
ENSVATH03238641 671 C>R No 1000Genomes
ENSVATH03238642 671 C>Y No 1000Genomes
tmp_5_13669993_T_C 672 F>L No 1000Genomes
ENSVATH03238643 677 S>T No 1000Genomes
ENSVATH03238644 678 S>R No 1000Genomes
ENSVATH07206366 684 R>H No 1000Genomes
ENSVATH07206370 695 F>L No 1000Genomes
tmp_5_13670075_G_A 699 C>Y No 1000Genomes
ENSVATH07206371 715 E>K No 1000Genomes
ENSVATH08513836 718 S>C No 1000Genomes
tmp_5_13670132_G_A 718 S>N No 1000Genomes
ENSVATH08513837 720 I>L No 1000Genomes
tmp_5_13670143_T_C 722 S>P No 1000Genomes
tmp_5_13670147_G_T 723 R>L No 1000Genomes
ENSVATH07206372 724 K>E No 1000Genomes
ENSVATH07206373 725 T>I No 1000Genomes
ENSVATH07206374 730 Y>H No 1000Genomes
ENSVATH14513503 731 V>M No 1000Genomes
ENSVATH07206375 738 F>Y No 1000Genomes
ENSVATH03238653 743 K>E No 1000Genomes
tmp_5_13670212_A_G 745 S>G No 1000Genomes
tmp_5_13670214_T_A 745 S>R No 1000Genomes
tmp_5_13670219_G_C 747 G>A No 1000Genomes
tmp_5_13670222_T_G 748 V>G No 1000Genomes
ENSVATH08513841 749 H>P No 1000Genomes
ENSVATH08513841 749 H>R No 1000Genomes
ENSVATH08513842 750 L>M No 1000Genomes
ENSVATH14513516 753 I>F No 1000Genomes
tmp_5_13670245_C_G 756 Q>E No 1000Genomes
ENSVATH11924081 757 H>D No 1000Genomes
ENSVATH03238654 759 L>F No 1000Genomes
tmp_5_13670257_C_T 760 P>S No 1000Genomes
tmp_5_13670265_C_A 762 H>Q No 1000Genomes
ENSVATH03238655 763 I>L No 1000Genomes
ENSVATH14513517 764 A>V No 1000Genomes
tmp_5_13670274_CAT_AAT,C 765 H>Q No 1000Genomes
ENSVATH03238657 767 Y>S No 1000Genomes
ENSVATH07206376 769 L>F No 1000Genomes
ENSVATH07206377 770 F>I No 1000Genomes
ENSVATH07206377 770 F>V No 1000Genomes
tmp_5_13670288_T_A 770 F>Y No 1000Genomes
tmp_5_13670293_C_G 772 H>D No 1000Genomes
ENSVATH03238659 772 H>R No 1000Genomes
ENSVATH03238660 774 E>D No 1000Genomes
tmp_5_13670302_G_T,A 775 E>* No 1000Genomes
tmp_5_13670302_G_T,A 775 E>K No 1000Genomes
ENSVATH11924082 777 P>T No 1000Genomes
tmp_5_13670312_T_C 778 M>T No 1000Genomes
ENSVATH03238662 791 E>Q No 1000Genomes
ENSVATH11924083 796 A>T No 1000Genomes
ENSVATH08513848 800 R>K No 1000Genomes
ENSVATH07206378 803 V>M No 1000Genomes
ENSVATH11924084 804 C>R No 1000Genomes
ENSVATH03238668 810 P>T No 1000Genomes
ENSVATH03238669 813 R>C No 1000Genomes
ENSVATH03238671 816 Q>E No 1000Genomes
ENSVATH03238674 821 S>P No 1000Genomes
ENSVATH07206381 831 G>R No 1000Genomes
ENSVATH07206382 832 S>L No 1000Genomes
ENSVATH08513852 838 D>N No 1000Genomes
tmp_5_13670514_A_T 845 E>D No 1000Genomes
ENSVATH08513858 845 E>Q No 1000Genomes
ENSVATH03238682 871 E>K No 1000Genomes
ENSVATH03238684 882 Y>H No 1000Genomes
ENSVATH03238685 883 K>R No 1000Genomes
tmp_5_13670651_A_C 891 Q>P No 1000Genomes

No associated diseases with Q9FJB5

3 regional properties for Q9FJB5

Type Name Position InterPro Accession
domain NB-ARC 167 - 412 IPR002182
domain Virus X resistance protein-like, coiled-coil domain 2 - 123 IPR038005
domain Rx, N-terminal 5 - 89 IPR041118

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ADP binding Binding to ADP, adenosine 5'-diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

2 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.

20 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F1MHT9 NLRC4 NLR family CARD domain-containing protein 4 Bos taurus (Bovine) SS
O14727 APAF1 Apoptotic protease-activating factor 1 Homo sapiens (Human) EV
Q9NPP4 NLRC4 NLR family CARD domain-containing protein 4 Homo sapiens (Human) SS
Q3UP24 Nlrc4 NLR family CARD domain-containing protein 4 Mus musculus (Mouse) EV
F1M649 Nlrc4 NLR family CARD domain-containing protein 4 Rattus norvegicus (Rat) SS
O22727 At1g61190 Probable disease resistance protein At1g61190 Arabidopsis thaliana (Mouse-ear cress) PR
O64790 At1g61300 Probable disease resistance protein At1g61300 Arabidopsis thaliana (Mouse-ear cress) PR
O64973 RPS5 Disease resistance protein RPS5 Arabidopsis thaliana (Mouse-ear cress) PR
P0C8S1 RPP8L2 Probable disease resistance RPP8-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
P60838 SUMM2 Disease resistance protein SUMM2 Arabidopsis thaliana (Mouse-ear cress) PR
Q38834 RPP13L4 Disease resistance RPP13-like protein 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q39214 RPM1 Disease resistance protein RPM1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8W3K3 At1g58400 Putative disease resistance protein At1g58400 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C646 RXW24L Probable disease resistance protein RXW24L Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRR4 RPPL1 Putative disease resistance RPP13-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9T048 At4g27190 Disease resistance protein At4g27190 Arabidopsis thaliana (Mouse-ear cress) PR
Q9XIF0 At1g59780 Putative disease resistance protein At1g59780 Arabidopsis thaliana (Mouse-ear cress) PR
O64789 At1g61310 Probable disease resistance protein At1g61310 Arabidopsis thaliana (Mouse-ear cress) PR
Q940K0 UNI Disease resistance protein UNI Arabidopsis thaliana (Mouse-ear cress) PR
Q9I9H8 apaf1 Apoptotic protease-activating factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) SS
10 20 30 40 50 60
MAEGVVSFGV QKLWALLNRE SERLNGIDEQ VDGLKRQLRG LQSLLKDADA KKHGSDRVRN
70 80 90 100 110 120
FLEDVKDLVF DAEDIIESYV LNKLRGEGKG VKNHVRRLAC FLTDRHKVAS DIEGITKRIS
130 140 150 160 170 180
KVIGEMQSLG IQQQIIDGGR SLSLQDIQRE IRQTFPNSSE SDLVGVEQSV EELVGPMVEI
190 200 210 220 230 240
DNIQVVSISG MGGIGKTTLA RQIFHHDLVR RHFDGFAWVC VSQQFTQKHV WQRILQELRP
250 260 270 280 290 300
HDGEILQMDE YTIQGKLFQL LETGRYLVVL DDVWKEEDWD RIKEVFPRKR GWKMLLTSRN
310 320 330 340 350 360
EGVGLHADPT CLSFRARILN PKESWKLFER IVPRRNETEY EEMEAIGKEM VTYCGGLPLA
370 380 390 400 410 420
VKVLGGLLAN KHTASEWKRV SENIGAQIVG KSCLDDNSLN SVYRILSLSY EDLPTDLKHC
430 440 450 460 470 480
FLYLAHFPED YKIKTRTLYS YWAAEGIYDG LTILDSGEDY LEELVRRNLV IAEKSNLSWR
490 500 510 520 530 540
LKLCQMHDMM REVCISKAKV ENFLQIIKVP TSTSTIIAQS PSRSRRLTVH SGKAFHILGH
550 560 570 580 590 600
KKKVRSLLVL GLKEDLWIQS ASRFQSLPLL RVLDLSSVKF EGGKLPSSIG GLIHLRFLSL
610 620 630 640 650 660
HQAVVSHLPS TIRNLKLMLY LNLHVAIGVP VHVPNVLKEM LELRYLSLPL DMHDKTKLEL
670 680 690 700 710 720
GDLVNLEYLW CFSTQHSSVT DLLRMTKLRF FGVSFSERCT FENLSSSLRQ FRKLETLSFI
730 740 750 760 770 780
YSRKTYMVDY VGEFVLDFIH LKKLSLGVHL SKIPDQHQLP PHIAHIYLLF CHMEEDPMPI
790 800 810 820 830 840
LEKLLHLKSV ELRRKAFIGR RMVCSKGGFP QLRALQISEQ SELEEWIVEE GSMPCLRDLI
850 860 870 880 890 900
IHSCEKLEEL PDGLKYVTSL KELKIEGMKR EWKEKLVGED YYKVQHIPDV QFFNCDDEQR
E