Q9FGW5
Gene name |
CDKG1 (At5g63370, K9H21.7) |
Protein name |
Cyclin-dependent kinase G1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G63370 |
EC number |
2.7.11.22: Protein-serine/threonine kinases |
Protein Class |
|

Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
443-466 (Activation loop from InterPro)
Target domain |
297-593 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
Autoinhibited structure

Activated structure

1 structures for Q9FGW5
Entry ID | Method | Resolution | Chain | Position | Source |
---|---|---|---|---|---|
AF-Q9FGW5-F1 | Predicted | AlphaFoldDB |
42 variants for Q9FGW5
Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
---|---|---|---|---|---|
tmp_5_25386764_C_G | 10 | R>T | No | 1000Genomes | |
tmp_5_25386719_C_T | 25 | G>D | No | 1000Genomes | |
ENSVATH12916899 | 27 | R>C | No | 1000Genomes | |
ENSVATH12916898 | 33 | Q>P | No | 1000Genomes | |
tmp_5_25386685_T_A | 36 | R>S | No | 1000Genomes | |
ENSVATH03469036 | 38 | D>N | No | 1000Genomes | |
tmp_5_25386641_A_T | 51 | L>H | No | 1000Genomes | |
ENSVATH07472409 | 55 | D>G | No | 1000Genomes | |
ENSVATH14646681 | 61 | R>L | No | 1000Genomes | |
ENSVATH12916897 | 65 | E>D | No | 1000Genomes | |
ENSVATH12916896 | 66 | K>Q | No | 1000Genomes | |
tmp_5_25386511_T_G | 94 | K>N | No | 1000Genomes | |
ENSVATH07472407 | 105 | K>N | No | 1000Genomes | |
ENSVATH07472406 | 122 | A>T | No | 1000Genomes | |
tmp_5_25386425_C_A | 123 | G>V | No | 1000Genomes | |
ENSVATH07472405 | 133 | A>T | No | 1000Genomes | |
ENSVATH07472403 | 150 | A>S | No | 1000Genomes | |
tmp_5_25386336_C_T | 153 | A>T | No | 1000Genomes | |
ENSVATH07472402 | 170 | Q>H | No | 1000Genomes | |
ENSVATH00749254 | 174 | E>K | No | 1000Genomes | |
tmp_5_25386194_C_A | 200 | G>V | No | 1000Genomes | |
tmp_5_25386183_G_A | 204 | P>S | No | 1000Genomes | |
ENSVATH12916884 | 210 | S>T | No | 1000Genomes | |
ENSVATH00749253 | 211 | V>D | No | 1000Genomes | |
ENSVATH03469034 | 225 | T>I | No | 1000Genomes | |
tmp_5_25386116_G_T | 226 | P>Q | No | 1000Genomes | |
tmp_5_25386065_C_T | 243 | G>E | No | 1000Genomes | |
ENSVATH07472400 | 251 | V>G | No | 1000Genomes | |
tmp_5_25386027_C_A | 256 | A>S | No | 1000Genomes | |
ENSVATH00749251 | 261 | G>D | No | 1000Genomes | |
tmp_5_25386005_T_C | 263 | E>G | No | 1000Genomes | |
tmp_5_25385999_T_C | 265 | Y>C | No | 1000Genomes | |
tmp_5_25385968_T_A | 275 | E>D | No | 1000Genomes | |
tmp_5_25385955_A_C | 280 | L>V | No | 1000Genomes | |
ENSVATH03469033 | 282 | P>L | No | 1000Genomes | |
ENSVATH03469032 | 284 | E>G | No | 1000Genomes | |
tmp_5_25385615_C_A | 393 | R>I | No | 1000Genomes | |
tmp_5_25385429_A_T | 455 | I>N | No | 1000Genomes | |
tmp_5_25385393_T_A | 467 | Y>F | No | 1000Genomes | |
ENSVATH00749250 | 481 | T>S | No | 1000Genomes | |
tmp_5_25385275_A_C | 506 | S>R | No | 1000Genomes | |
ENSVATH00749248 | 517 | V>I | No | 1000Genomes |
No associated diseases with Q9FGW5
Functions
Description | ||
---|---|---|
EC Number | 2.7.11.22 | Protein-serine/threonine kinases |
Subcellular Localization |
|
|
PANTHER Family | ||
PANTHER Subfamily | ||
PANTHER Protein Class | ||
PANTHER Pathway Category | No pathway information available |
3 GO annotations of cellular component
Name | Definition |
---|---|
nuclear speck | A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. |
nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
spliceosomal complex | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
3 GO annotations of molecular function
Name | Definition |
---|---|
ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
cyclin-dependent protein serine/threonine kinase activity | Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
6 GO annotations of biological process
Name | Definition |
---|---|
meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
mRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
pollen exine formation | The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine. |
protein phosphorylation | The process of introducing a phosphate group on to a protein. |
regulation of (1->3)-beta-D-glucan biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. |
regulation of mitotic cell cycle | Any process that modulates the rate or extent of progress through the mitotic cell cycle. |
11 homologous proteins in AiPD
UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
---|---|---|---|---|
Q2TBL8 | CDK10 | Cyclin-dependent kinase 10 | Bos taurus (Bovine) | PR |
Q15131 | CDK10 | Cyclin-dependent kinase 10 | Homo sapiens (Human) | PR |
P21127 | CDK11B | Cyclin-dependent kinase 11B | Homo sapiens (Human) | PR |
Q9UQ88 | CDK11A | Cyclin-dependent kinase 11A | Homo sapiens (Human) | PR |
Q3UMM4 | Cdk10 | Cyclin-dependent kinase 10 | Mus musculus (Mouse) | PR |
Q4KM47 | Cdk10 | Cyclin-dependent kinase 10 | Rattus norvegicus (Rat) | PR |
Q09437 | cdk-11.1 | Cyclin-dependent kinase 11.1 | Caenorhabditis elegans | PR |
Q9C9U2 | CDKD-1 | Cyclin-dependent kinase D-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q9LMT0 | CDKD-3 | Cyclin-dependent kinase D-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q9ZVM9 | At1g54610 | Probable serine/threonine-protein kinase At1g54610 | Arabidopsis thaliana (Mouse-ear cress) | PR |
F4I114 | At1g09600 | Probable serine/threonine-protein kinase At1g09600 | Arabidopsis thaliana (Mouse-ear cress) | PR |
10 | 20 | 30 | 40 | 50 | 60 |
MAAGGVDVSR | SSVAVKKDYD | FYRNGSRDVY | VRQSGRDDER | RQIKRPSDHD | LRRNDGRHRS |
70 | 80 | 90 | 100 | 110 | 120 |
RLAYEKGELR | EEAEVQRPSE | KRRKFSPIVW | NAEKVGRAPS | REKTKSPFPV | PTTTVISNQA |
130 | 140 | 150 | 160 | 170 | 180 |
VAGKTTSNDQ | VNALMSPEPS | YLAPVQPSEA | LLAVKHPVDD | LEEGQLEEEQ | VMQEDVKEGL |
190 | 200 | 210 | 220 | 230 | 240 |
LEEEQVMQEP | NIKTSRWGTG | LTSPKEELIS | VNVSKTNRWN | RSSLTPECEE | VMVSEEQQCY |
250 | 260 | 270 | 280 | 290 | 300 |
SSGSGSGHLS | VEKLSADGNS | GREYYSSDHD | ELEHEDQDSL | TPGEMNMMFG | SRSVNEFQKL |
310 | 320 | 330 | 340 | 350 | 360 |
NKINEGTYGI | VYKARDEKTK | EIVALKKIKM | KEDRFEEEYG | FPLTSLREIN | ILLSCNHPAI |
370 | 380 | 390 | 400 | 410 | 420 |
VNVKEVVVGG | KNDNDVYMVM | EHLEHDLRGV | MDRRKEPFST | SEVKCLMMQL | LDGLKYLHTN |
430 | 440 | 450 | 460 | 470 | 480 |
WIIHRDLKPS | NLLMNNCGEL | KICDFGMARQ | YGSPIKPYTQ | MVITQWYRPP | ELLLGAKEYS |
490 | 500 | 510 | 520 | 530 | 540 |
TAVDMWSVGC | IMAELLSQKP | LFPGKSELDQ | LQKIFAVLGT | PNEAIWPGFS | SFPNAKAKFP |
550 | 560 | 570 | 580 | 590 | 600 |
TQPYNMLRKK | FPAISFVGGQ | ILSERGFDLL | NSLLTLDPEK | RLTVEDALNH | GWFHEVPLPK |
610 | |||||
SKDFMPTYPP | KR |