Q9FFQ1

PR
Gene name
RH31 (At5g63630, MBK5.11)
Protein name
DEAD-box ATP-dependent RNA helicase 31
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G63630
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FFQ1

Entry ID Method Resolution Chain Position Source
AF-Q9FFQ1-F1 Predicted AlphaFoldDB

75 variants for Q9FFQ1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03470522 4 N>K No 1000Genomes
ENSVATH07473719 5 F>L No 1000Genomes
ENSVATH09560732 6 P>H No 1000Genomes
tmp_5_25475742_C_A 13 A>S No 1000Genomes
ENSVATH03470521 14 H>Y No 1000Genomes
ENSVATH00749719 17 S>P No 1000Genomes
tmp_5_25475729_G_C 17 S>W No 1000Genomes
ENSVATH03470519 25 T>P No 1000Genomes
tmp_5_25475666_G_C 38 S>C No 1000Genomes
tmp_5_25475659_C_A 40 L>F No 1000Genomes
ENSVATH03470518 50 N>D No 1000Genomes
ENSVATH00749717 50 N>K No 1000Genomes
ENSVATH03470517 51 F>L No 1000Genomes
tmp_5_25475605_A_C,G 58 D>E No 1000Genomes
tmp_5_25475592_C_G 63 E>Q No 1000Genomes
ENSVATH03470516 66 I>S No 1000Genomes
ENSVATH12919478 83 E>K No 1000Genomes
ENSVATH00749715 90 S>T No 1000Genomes
tmp_5_25475484_C_T 99 G>R No 1000Genomes
ENSVATH00749713 100 I>L No 1000Genomes
ENSVATH07473717 105 D>N No 1000Genomes
tmp_5_25475459_T_C 107 D>G No 1000Genomes
ENSVATH07473716 110 D>G No 1000Genomes
ENSVATH03470513 112 S>G No 1000Genomes
ENSVATH03470512 118 E>D No 1000Genomes
ENSVATH07473714 119 K>N No 1000Genomes
tmp_5_25475400_C_T 127 D>N No 1000Genomes
ENSVATH12919477 127 D>V No 1000Genomes
tmp_5_25475391_T_C 130 R>G No 1000Genomes
tmp_5_25475378_T_A 134 Y>F No 1000Genomes
ENSVATH12919476 151 S>I No 1000Genomes
ENSVATH03470511 151 S>R No 1000Genomes
ENSVATH00749712 158 R>K No 1000Genomes
tmp_5_25475300_T_G 160 E>A No 1000Genomes
ENSVATH03470508 170 E>* No 1000Genomes
ENSVATH03470507 170 E>D No 1000Genomes
ENSVATH07473713 194 V>E No 1000Genomes
ENSVATH12919475 197 D>A No 1000Genomes
ENSVATH07473712 208 E>K No 1000Genomes
ENSVATH07473711 212 D>G No 1000Genomes
ENSVATH07473710 215 F>L No 1000Genomes
tmp_5_25475133_G_T 216 L>I No 1000Genomes
ENSVATH12919464 216 L>R No 1000Genomes
tmp_5_25475036_G_A 248 T>I No 1000Genomes
tmp_5_25474882_G_A 254 P>S No 1000Genomes
ENSVATH00749708 261 K>T No 1000Genomes
tmp_5_25474852_T_C 264 K>E No 1000Genomes
ENSVATH03470496 281 I>T No 1000Genomes
tmp_5_25474508_T_A 294 T>S No 1000Genomes
ENSVATH03470479 321 K>N No 1000Genomes
tmp_5_25474334_G_A 322 R>* No 1000Genomes
tmp_5_25474263_G_C 345 N>K No 1000Genomes
ENSVATH07473704 371 R>L No 1000Genomes
tmp_5_25474172_G_A 376 P>S No 1000Genomes
ENSVATH03470476 378 Q>K No 1000Genomes
tmp_5_25474011_C_T 392 E>K No 1000Genomes
ENSVATH12919432 399 T>P No 1000Genomes
ENSVATH12919431 414 H>Y No 1000Genomes
ENSVATH03470473 421 R>H No 1000Genomes
tmp_5_25473717_C_T 457 R>K No 1000Genomes
ENSVATH12919427 461 E>K No 1000Genomes
ENSVATH07473699 482 M>I No 1000Genomes
tmp_5_25473636_G_T 484 A>E No 1000Genomes
ENSVATH14647002 485 S>P No 1000Genomes
tmp_5_25473624_C_A 488 R>I No 1000Genomes
ENSVATH07473698 499 E>K No 1000Genomes
ENSVATH00749700 503 G>D No 1000Genomes
ENSVATH03470469 505 V>I No 1000Genomes
tmp_5_25473442_C_G 522 V>L No 1000Genomes
ENSVATH03470459 623 D>N No 1000Genomes
ENSVATH03470459 623 D>Y No 1000Genomes
tmp_5_25472804_C_T 649 V>I No 1000Genomes
ENSVATH12919423 702 L>I No 1000Genomes
ENSVATH03470449 703 G>S No 1000Genomes
tmp_5_25472636_T_A 705 M>L No 1000Genomes

No associated diseases with Q9FFQ1

4 regional properties for Q9FFQ1

Type Name Position InterPro Accession
domain Helicase, C-terminal 494 - 643 IPR001650
domain DEAD/DEAH box helicase domain 273 - 450 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 267 - 472 IPR014001
domain RNA helicase, DEAD-box type, Q motif 248 - 276 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8K363 Ddx18 ATP-dependent RNA helicase DDX18 Mus musculus (Mouse) PR
Q0DBS1 Os06g0535100 Putative DEAD-box ATP-dependent RNA helicase 51 Oryza sativa subsp japonica (Rice) PR
O80792 RH33 Putative DEAD-box ATP-dependent RNA helicase 33 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LIH9 RH51 DEAD-box ATP-dependent RNA helicase 51 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SB89 RH27 DEAD-box ATP-dependent RNA helicase 27 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SA27 RH36 DEAD-box ATP-dependent RNA helicase 36 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FVV4 RH55 DEAD-box ATP-dependent RNA helicase 55 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAI7 TIF4A-3 Eukaryotic initiation factor 4A-3 Arabidopsis thaliana (Mouse-ear cress) PR
O22907 RH24 DEAD-box ATP-dependent RNA helicase 24 Arabidopsis thaliana (Mouse-ear cress) PR
Q56X76 RH39 DEAD-box ATP-dependent RNA helicase 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY84 RH10 DEAD-box ATP-dependent RNA helicase 10 Arabidopsis thaliana (Mouse-ear cress) PR
Q84TG1 RH57 DEAD-box ATP-dependent RNA helicase 57 Arabidopsis thaliana (Mouse-ear cress) PR
P41377 TIF4A-2 Eukaryotic initiation factor 4A-2 Arabidopsis thaliana (Mouse-ear cress) PR
P41376 EIF4A1 Eukaryotic initiation factor 4A-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H0U8 RH42 DEAD-box ATP-dependent RNA helicase 42 Arabidopsis thaliana (Mouse-ear cress) SS
10 20 30 40 50 60
MPLNFPLRIR FFAHSLSGTH LSYNTSSSVP LLFRIFSSGL NHFEFGSRIN FSTRPNRDQP
70 80 90 100 110 120
EFERRIRDGG EIRASKSLIE DEEELSNWVS GFRTGSSRGI LKSDDEDEED RSRGRNQEKR
130 140 150 160 170 180
GIRNQVDSFR NKRYGGDRER GFNSRIQGKS SEASFRGRKE TSFSRDREDE KGLRKREDLR
190 200 210 220 230 240
LEDESSDEDV KSLVMGDIGD LLSEDDEEED QDYDFLKKKA VSAFGFDKEN VIEADKTRNA
250 260 270 280 290 300
NDSYLTKTRF DHYPLSPLSL KAIKDAGYET MTVVQEATLP IILKGKDVLA KAKTGTGKTV
310 320 330 340 350 360
AFLLPSIEVV VKSPPTSPDN KRPPILALVI CPTRELANQA ATEANTLLKY HPSIGVQVVI
370 380 390 400 410 420
GGTRLGLEQK RMQTNPCQIL VATPGRLKDH IENTPGFATR LKGVKVLVLD EADHLLDMGF
430 440 450 460 470 480
RKDIERIISA VPKERQTFLF SATVPEEVRQ ICLVALRRDH EFVNCVHEGT IETHQQVRQM
490 500 510 520 530 540
HMIASLDRHF SLLYTLLREH IMGNVDYKVI VFCTTAMVTK LVADLLGELN LNVREIHSRK
550 560 570 580 590 600
PQSYRTRVSN EFRKSKGLIL VTSDVSARGV DYPDVTLVLQ VGLPKDREQY IHRLGRTGRK
610 620 630 640 650 660
GKEGEGILLL APWEEYFLSS LKDLPITKSP LPSIDPETVK KVQKALCHVE MRNKEAAYQA
670 680 690 700 710
WLGYYNSQKM IGRDKDRLVE LANEFSRSMG LDNPPAIPKL ILGKMGLKNV PGLRAK