Q9FF14

PR
Gene name
FH19 (At5g07780, MXM12.2)
Protein name
Formin-like protein 19
Names
AtFH19
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G07780
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

95-168 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FF14

Entry ID Method Resolution Chain Position Source
AF-Q9FF14-F1 Predicted AlphaFoldDB

53 variants for Q9FF14

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_2479714_T_C 3 L>P No 1000Genomes
ENSVATH03035766 10 Y>D No 1000Genomes
ENSVATH03035766 10 Y>N No 1000Genomes
tmp_5_2479744_T_C 13 V>A No 1000Genomes
tmp_5_2479860_C_T 52 R>C No 1000Genomes
tmp_5_2479891_C_T 62 P>L No 1000Genomes
ENSVATH10642449 64 L>R No 1000Genomes
ENSVATH06938570 67 P>L No 1000Genomes
ENSVATH06938571 74 T>A No 1000Genomes
tmp_5_2479956_G_C 84 V>L No 1000Genomes
ENSVATH10642451 93 S>T No 1000Genomes
ENSVATH00611345 103 E>A No 1000Genomes
ENSVATH03035771 121 S>P No 1000Genomes
tmp_5_2480195_G_A 124 E>K No 1000Genomes
ENSVATH03035772 126 I>L No 1000Genomes
ENSVATH03035773 129 L>V No 1000Genomes
ENSVATH03035775 134 K>R No 1000Genomes
ENSVATH03035776 138 E>K No 1000Genomes
ENSVATH00611346 140 E>Q No 1000Genomes
tmp_5_2480652_A_C 190 N>T No 1000Genomes
ENSVATH03035781 195 K>E No 1000Genomes
ENSVATH13956029 196 E>K No 1000Genomes
tmp_5_2480968_A_G 216 Q>R No 1000Genomes
ENSVATH03035784 243 Q>K No 1000Genomes
tmp_5_2481190_A_G 245 T>A No 1000Genomes
tmp_5_2481193_A_G 246 K>E No 1000Genomes
tmp_5_2481200_C_A 248 T>N No 1000Genomes
tmp_5_2481227_C_G 257 A>G No 1000Genomes
ENSVATH03035789 286 G>A No 1000Genomes
ENSVATH06938582 289 R>S No 1000Genomes
ENSVATH10642569 326 S>A No 1000Genomes
tmp_5_2481813_A_T 333 K>* No 1000Genomes
ENSVATH03035804 336 E>Q No 1000Genomes
ENSVATH06938583 337 S>N No 1000Genomes
ENSVATH03035812 345 Q>H No 1000Genomes
ENSVATH03035811 345 Q>K No 1000Genomes
ENSVATH10642595 346 L>V No 1000Genomes
ENSVATH06938585 354 Q>H No 1000Genomes
ENSVATH03035814 355 A>D No 1000Genomes
ENSVATH06938586 356 I>V No 1000Genomes
tmp_5_2481979_G_T 364 K>N No 1000Genomes
ENSVATH03035815 367 L>I No 1000Genomes
ENSVATH03035817 372 T>S No 1000Genomes
tmp_5_2482235_G_A 399 M>I No 1000Genomes
tmp_5_2482520_C_G 426 T>S No 1000Genomes
ENSVATH10642599 427 A>T No 1000Genomes
tmp_5_2482531_T_A 430 L>M No 1000Genomes
tmp_5_2482559_C_G 439 A>G No 1000Genomes
tmp_5_2482579_C_G 446 Q>E No 1000Genomes
ENSVATH03035819 448 E>D No 1000Genomes
tmp_5_2482603_G_A 454 A>T No 1000Genomes
tmp_5_2482613_A_T 457 E>V No 1000Genomes
ENSVATH06938593 460 M>L No 1000Genomes

No associated diseases with Q9FF14

1 regional properties for Q9FF14

Type Name Position InterPro Accession
domain Formin, FH2 domain 68 - 464 IPR015425

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
actin binding Binding to monomeric or multimeric forms of actin, including actin filaments.

2 GO annotations of biological process

Name Definition
actin nucleation The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
barbed-end actin filament capping The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A0A1D5P556 DAAM2 Disheveled-associated activator of morphogenesis 2 Gallus gallus (Chicken) SS
O95466 FMNL1 Formin-like protein 1 Homo sapiens (Human) SS
Q27J81 INF2 Inverted formin-2 Homo sapiens (Human) EV
Q9Y4D1 DAAM1 Disheveled-associated activator of morphogenesis 1 Homo sapiens (Human) EV
Q86T65 DAAM2 Disheveled-associated activator of morphogenesis 2 Homo sapiens (Human) SS
Q80U19 Daam2 Disheveled-associated activator of morphogenesis 2 Mus musculus (Mouse) SS
Q8BPM0 Daam1 Disheveled-associated activator of morphogenesis 1 Mus musculus (Mouse) PR
Q0GNC1 Inf2 Inverted formin-2 Mus musculus (Mouse) SS
Q0QWG9 Grid2ip Delphilin Mus musculus (Mouse) PR
Q9C7S1 FH12 Formin-like protein 12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LH02 FH17 Formin-like protein 17 Arabidopsis thaliana (Mouse-ear cress) PR
P0C5K4 FH21A Putative formin-like protein 21a Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSLVDISGAY SLVPLPPPPP PLMRRRAPLP PPPPPPLMRR RAPPPPPPPL MRRRAPPPPP
70 80 90 100 110 120
PPPLPRPCSR PPKTKCSLKP LHWVKKTRAL PGSLWDELQR RQECRDIEDE QILCAIELSV
130 140 150 160 170 180
SEIETIFSLG AKPKPKPEPE KVPLIDLRRA TNTEIRLMLL NIRLPDMIAA AMAMDESRLD
190 200 210 220 230 240
DFDQIENLIN LFPTKEDMKF LLTYTGDKGN CEQLFQYLQE VVKVPRVESK LRVFSFKIQF
250 260 270 280 290 300
GTQITKLTKG LNAVNSACEE IRTSQKLKDI MENILCLGNI LNQGTGRGRA VGFRLDSLLI
310 320 330 340 350 360
LSETRADNSK MTLMHYLCKV LASKASDLLD FHKDLESLES ASKIQLKSLA EEIQAITKGL
370 380 390 400 410 420
EKLKQELTAS ETDGPVSQVF RKLLKEFISN AETQVATVMA LYYPARGNAE ALAHYFGYHY
430 440 450 460
PFEQVTATLL SFIRLFKKAH EENVKQAELE KKKAAKEAEM EKTK