Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FE79

Entry ID Method Resolution Chain Position Source
AF-Q9FE79-F1 Predicted AlphaFoldDB

12 variants for Q9FE79

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07365871 77 Y>H No 1000Genomes
ENSVATH07365869 89 V>L No 1000Genomes
tmp_5_19421926_T_A 93 L>F No 1000Genomes
ENSVATH07365865 137 A>S No 1000Genomes
tmp_5_19421784_C_A 141 E>* No 1000Genomes
tmp_5_19421697_G_C 170 L>V No 1000Genomes
ENSVATH07365863 171 T>M No 1000Genomes
ENSVATH12616170 174 T>K No 1000Genomes
ENSVATH12616167 213 E>D No 1000Genomes
tmp_5_19421564_G_A 214 S>F No 1000Genomes
ENSVATH03384782 215 K>R No 1000Genomes
ENSVATH03384780 222 T>R No 1000Genomes

No associated diseases with Q9FE79

1 regional properties for Q9FE79

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 15 - 169 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endosome A vacuole to which materials ingested by endocytosis are delivered.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

24 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3MHP2 RAB11B Ras-related protein Rab-11B Bos taurus (Bovine) PR
Q2TA29 RAB11A Ras-related protein Rab-11A Bos taurus (Bovine) PR
Q5ZJN2 RAB11A Ras-related protein Rab-11A Gallus gallus (Chicken) PR
Q5ZHV1 RAB33B Ras-related protein Rab-33B Gallus gallus (Chicken) PR
P62490 RAB11A Ras-related protein Rab-11A Canis lupus familiaris (Dog) (Canis familiaris) PR
P62491 RAB11A Ras-related protein Rab-11A Homo sapiens (Human) PR
Q15907 RAB11B Ras-related protein Rab-11B Homo sapiens (Human) PR
Q96AX2 RAB37 Ras-related protein Rab-37 Homo sapiens (Human) PR
Q9H082 RAB33B Ras-related protein Rab-33B Homo sapiens (Human) PR
P46638 Rab11b Ras-related protein Rab-11B Mus musculus (Mouse) PR
P62492 Rab11a Ras-related protein Rab-11A Mus musculus (Mouse) PR
Q9JKM7 Rab37 Ras-related protein Rab-37 Mus musculus (Mouse) PR
O35963 Rab33b Ras-related protein Rab-33B Mus musculus (Mouse) PR
Q52NJ1 RAB11A Ras-related protein Rab-11A Sus scrofa (Pig) PR
O35509 Rab11b Ras-related protein Rab-11B Rattus norvegicus (Rat) PR
P62494 Rab11a Ras-related protein Rab-11A Rattus norvegicus (Rat) PR
P25766 RGP1 Ras-related protein RGP1 Oryza sativa subsp japonica (Rice) PR
Q20365 rab-33 Ras-related protein Rab-33 Caenorhabditis elegans PR
O04486 RABA2A Ras-related protein RABA2a Arabidopsis thaliana (Mouse-ear cress) PR
O49513 RABA1E Ras-related protein RABA1e Arabidopsis thaliana (Mouse-ear cress) PR
Q9LH50 RABA4D Ras-related protein RABA4d Arabidopsis thaliana (Mouse-ear cress) PR
Q9LNK1 RABA3 Ras-related protein RABA3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LNW1 RABA2B Ras-related protein RABA2b Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJZ5 RABA4E Putative Ras-related protein RABA4e Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSKFQSNFNQ KIDYVFKVVL IGDSAVGKSQ LLARFSRNEF SIESKATIGV EFQTRTLEID
70 80 90 100 110 120
RKTIKAQIWD TAGQERYRAV TSAYYRGAVG AMLVYDITKR QSFDHVARWL EELRGHADKN
130 140 150 160 170 180
IVIMLIGNKT DLGTLRAVPT EDAKEFAQRE NLFFMETSAL DSNNVEPSFL TVLTEIYRIV
190 200 210 220
SKKNLVANEE GESGGDSSLL QGTKIVVAGE ETESKGKGCC GTS