Q9DED6

PR
Gene name
BARX1B
Protein name
Homeobox protein BarH-like 1b
Names
Bar class homeoprotein Barx1b
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:374017
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-247 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9DED6

Entry ID Method Resolution Chain Position Source
AF-Q9DED6-F1 Predicted AlphaFoldDB

No variants for Q9DED6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9DED6

No associated diseases with Q9DED6

2 regional properties for Q9DED6

Type Name Position InterPro Accession
domain Homeobox domain 56 - 120 IPR001356
conserved_site Homeobox, conserved site 91 - 114 IPR017970

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II transcription regulatory region sequence-specific DNA binding Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9W6D8 BARX1 Homeobox protein BarH-like 1 Gallus gallus (Chicken) PR
Q9UMQ3 BARX2 Homeobox protein BarH-like 2 Homo sapiens (Human) PR
Q9HBU1 BARX1 Homeobox protein BarH-like 1 Homo sapiens (Human) PR
Q9ER42 Barx1 Homeobox protein BarH-like 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MQHPLELGAA HYFPAEAFPD HRSHRYRSFM IEEILTDPPD AKGTAPPGEL LKFGVQALLS
70 80 90 100 110 120
ARPYHSHLAV LKAEPAAVFK FPLAPLGCSG LGSALLAAGS GLQGGSASPH LPLELHLRGK
130 140 150 160 170 180
LEPGGPETGS KAKKGRRSRT VFTELQLMGL EKRFEKQKYL STPDRIDLAE SLGLSQLQVK
190 200 210 220 230 240
TWYQNRRMKW KKIVLQGGGL ESPTKPKGRP KKNSIPSSEQ LSEQERARDA EKPPESLGSP
AEVSQEE