AiPD: Autoinhibited Protein Database

Gene name	Susd2
Protein name	Sushi domain-containing protein 2
Names
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:71733
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

343-417 (Predicted disordered autoinhibitory region) PR

343-417 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
2CQW	NMR	-	A	16-86	PDB
AF-Q9DBX3-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3389049279	17	P>L	No	EVA
rs3389117624	28	S>T	No	EVA
rs3389113339	38	G>*	No	EVA
rs3389110004	39	L>P	No	EVA
rs3389106174	55	D>E	No	EVA
rs30005620	64	L>S	No	EVA
rs3389102894	106	D>V	No	EVA
rs3389080708	114	S>*	No	EVA
rs3401425060	136	P>T	No	EVA
rs3389085760	160	E>D	No	EVA
rs3389073314	166	Y>F	No	EVA
rs1132036225	199	T>K	No	EVA
rs3389104844	243	V>M	No	EVA
rs3389117632	247	R>G	No	EVA
rs3389080642	263	L>P	No	EVA
rs3389106973	277	D>E	No	EVA
rs242246466	280	A>E	No	EVA
rs3389073247	284	A>G	No	EVA
rs3389117691	297	E>D	No	EVA
rs3401392273	305	T>A	No	EVA
rs252878483	305	T>M	No	EVA
rs3389073272	308	P>S	No	EVA
rs3389115408	309	D>E	No	EVA
rs3389073282	326	T>S	No	EVA
rs3389085752	333	E>D	No	EVA
rs3389049373	361	Q>H	No	EVA
rs3389110013	364	C>R	No	EVA
rs3389110854	424	P>S	No	EVA
rs3389080669	428	K>T	No	EVA
rs3389085815	434	D>Y	No	EVA
rs3389104889	446	A>V	No	EVA
rs3412056149	467	E>*	No	EVA
rs247830180	488	R>K	No	EVA
rs213711685	532	V>A	No	EVA
rs3401425099	534	S>N	No	EVA
rs3401343295	536	T>S	No	EVA
rs3401331212	552	A>T	No	EVA
rs3389073332	570	V>I	No	EVA
rs3389073332	570	V>L	No	EVA
rs3389108112	592	L>F	No	EVA
rs3389110885	631	S>C	No	EVA
rs213504278	673	T>P	No	EVA
rs227244338	676	V>M	No	EVA
rs3389100117	685	F>I	No	EVA
rs3389108047	691	M>I	No	EVA
rs264788252	696	S>P	No	EVA
rs3389073315	703	R>W	No	EVA
rs248365239	710	Q>H	No	EVA
rs3389085802	711	H>Q	No	EVA
rs259342810	749	N>D	No	EVA
rs3389093888	783	V>A	No	EVA
rs3389110003	784	L>I	No	EVA
rs3389049288	800	I>N	No	EVA
rs3389073328	815	M>T	No	EVA

Type	Name	Position	InterPro Accession
domain	Sushi/SCR/CCP domain	720 - 777	IPR000436
domain	Somatomedin B domain	25 - 64	IPR001212
domain	von Willebrand factor, type D domain	433 - 636	IPR001846
domain	AMOP domain	282 - 430	IPR005533

		Description
EC Number
Subcellular Localization	Cell membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
extracellular space	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Name	Definition
No GO annotations for molecular function

Name	Definition
negative regulation of cell cycle G1/S phase transition	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
negative regulation of cell division	Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q21874	R09E10.5	Uncharacterized protein R09E10.5	Caenorhabditis elegans	PR
P34501	K03H1.5	Uncharacterized protein K03H1.5	Caenorhabditis elegans	PR