Q9C8X7
PR
Gene name |
UBC31 (At1g36340, F7F23.6) |
Protein name |
Probable ubiquitin-conjugating enzyme E2 31 |
Names |
E2 ubiquitin-conjugating enzyme 31, Ubiquitin carrier protein 31 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G36340 |
EC number |
2.3.2.23: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9C8X7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9C8X7-F1 | Predicted | AlphaFoldDB |
41 variants for Q9C8X7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04772927 | 8 | K>R | No | 1000Genomes | |
| tmp_1_13684899_G_A | 9 | A>V | No | 1000Genomes | |
| ENSVATH04772926 | 10 | A>V | No | 1000Genomes | |
| ENSVATH04772925 | 14 | A>S | No | 1000Genomes | |
| ENSVATH01217333 | 18 | R>K | No | 1000Genomes | |
| ENSVATH00071578 | 21 | I>N | No | 1000Genomes | |
| ENSVATH00071578 | 21 | I>T | No | 1000Genomes | |
| ENSVATH07569617 | 47 | D>G | No | 1000Genomes | |
| ENSVATH07569618 | 47 | D>N | No | 1000Genomes | |
| tmp_1_13684307_C_T | 48 | G>D | No | 1000Genomes | |
| ENSVATH04772890 | 49 | T>A | No | 1000Genomes | |
| tmp_1_13684301_G_C | 50 | P>R | No | 1000Genomes | |
| ENSVATH04772889 | 52 | E>G | No | 1000Genomes | |
| tmp_1_13684292_C_T | 53 | G>D | No | 1000Genomes | |
| ENSVATH13049078 | 54 | G>D | No | 1000Genomes | |
| ENSVATH13049078 | 54 | G>V | No | 1000Genomes | |
| ENSVATH01217300 | 58 | L>V | No | 1000Genomes | |
| ENSVATH04772888 | 62 | F>Y | No | 1000Genomes | |
| ENSVATH13049077 | 64 | T>K | No | 1000Genomes | |
| tmp_1_13684253_T_A | 66 | Y>F | No | 1000Genomes | |
| ENSVATH01217290 | 73 | F>V | No | 1000Genomes | |
| ENSVATH01217287 | 76 | K>I | No | 1000Genomes | |
| ENSVATH01217286 | 82 | P>L | No | 1000Genomes | |
| tmp_1_13684092_C_T | 87 | E>K | No | 1000Genomes | |
| ENSVATH01217284 | 92 | M>I | No | 1000Genomes | |
| ENSVATH00071574 | 93 | N>D | No | 1000Genomes | |
| ENSVATH01217283 | 98 | K>R | No | 1000Genomes | |
| tmp_1_13684055_C_T | 99 | W>* | No | 1000Genomes | |
| ENSVATH01217281 | 102 | A>S | No | 1000Genomes | |
| ENSVATH01217279 | 104 | M>I | No | 1000Genomes | |
| ENSVATH13049075 | 104 | M>L | No | 1000Genomes | |
| ENSVATH01217280 | 104 | M>T | No | 1000Genomes | |
| ENSVATH01217274 | 113 | L>I | No | 1000Genomes | |
| ENSVATH00071573 | 128 | E>D | No | 1000Genomes | |
| ENSVATH13049052 | 134 | K>M | No | 1000Genomes | |
| tmp_1_13683846_C_T | 137 | R>K | No | 1000Genomes | |
| ENSVATH04772883 | 141 | D>N | No | 1000Genomes | |
| ENSVATH13049051 | 142 | Q>R | No | 1000Genomes | |
| ENSVATH04772882 | 146 | E>K | No | 1000Genomes | |
| ENSVATH14123928 | 151 | H>Q | No | 1000Genomes | |
| ENSVATH01217271 | 154 | N>D | No | 1000Genomes |
No associated diseases with Q9C8X7
4 regional properties for Q9C8X7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | FKBP-type peptidyl-prolyl cis-trans isomerase domain | 41 - 132 | IPR001179 |
| repeat | Tetratricopeptide repeat | 160 - 193 | IPR019734-1 |
| repeat | Tetratricopeptide repeat | 208 - 241 | IPR019734-2 |
| repeat | Tetratricopeptide repeat | 242 - 275 | IPR019734-3 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.23 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ubiquitin conjugating enzyme activity | Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein polyubiquitination | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. |
| ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. |
18 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32LD2 | UBE2T | Ubiquitin-conjugating enzyme E2 T | Bos taurus (Bovine) | PR |
| Q5ZJJ5 | AKTIP | AKT-interacting protein | Gallus gallus (Chicken) | PR |
| P35128 | ben | Ubiquitin-conjugating enzyme E2 N | Drosophila melanogaster (Fruit fly) | PR |
| P25867 | eff | Ubiquitin-conjugating enzyme E2-17 kDa | Drosophila melanogaster (Fruit fly) | PR |
| Q9NPD8 | UBE2T | Ubiquitin-conjugating enzyme E2 T | Homo sapiens (Human) | PR |
| Q96LR5 | UBE2E2 | Ubiquitin-conjugating enzyme E2 E2 | Homo sapiens (Human) | PR |
| Q969T4 | UBE2E3 | Ubiquitin-conjugating enzyme E2 E3 | Homo sapiens (Human) | PR |
| Q9H8T0 | AKTIP | AKT-interacting protein | Homo sapiens (Human) | PR |
| Q9CQ37 | Ube2t | Ubiquitin-conjugating enzyme E2 T | Mus musculus (Mouse) | PR |
| P52483 | Ube2e3 | Ubiquitin-conjugating enzyme E2 E3 | Mus musculus (Mouse) | PR |
| P61079 | Ube2d3 | Ubiquitin-conjugating enzyme E2 D3 | Mus musculus (Mouse) | PR |
| Q64362 | Aktip | AKT-interacting protein | Mus musculus (Mouse) | PR |
| Q5FVH4 | Aktip | AKT-interacting protein | Rattus norvegicus (Rat) | PR |
| P35129 | let-70 | Ubiquitin-conjugating enzyme E2 2 | Caenorhabditis elegans | PR |
| Q9SLE4 | UBC29 | Ubiquitin-conjugating enzyme E2 29 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSP7 | UBC32 | Ubiquitin-conjugating enzyme E2 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FF66 | UBC22 | Ubiquitin-conjugating enzyme E2 22 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9LJD7 | COP10 | Constitutive photomorphogenesis protein 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFKKMDKKAA | QRIAMEYRAM | ISKESLFSIG | QNSNNIYEWT | AVIRGPDGTP | YEGGMFNLSI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KFPTDYPFKP | PKFTFKTPIY | HPNINDEGSI | CMNILKDKWT | PALMVEKVLL | SILLLLEKPN |
| 130 | 140 | 150 | |||
| PDDPLVPEIG | QLFKNNRFQF | DQRAREFTAR | HANN |