Q9BRR0
PR
Gene name |
ZKSCAN3 (ZFP47, ZNF306, ZNF309, ZSCAN13) |
Protein name |
Zinc finger protein with KRAB and SCAN domains 3 |
Names |
Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 309, Zinc finger protein 47 homolog, Zf47, Zfp-47 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:80317 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9BRR0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9BRR0-F1 | Predicted | AlphaFoldDB |
377 variants for Q9BRR0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs733743 VAR_024208 CA3683962 |
3 | R>T | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1158689033 CA362892865 |
4 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
rs148473672 CA135849592 |
6 | S>N | No |
ClinGen ESP |
|
|
rs750732338 CA3683963 |
8 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA3683964 rs756543401 |
11 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA362893001 rs1561936464 |
12 | D>N | No |
ClinGen Ensembl |
|
|
CA362893008 rs1289776007 |
12 | D>V | No |
ClinGen gnomAD |
|
|
CA135849594 rs942643668 |
14 | Q>K | No |
ClinGen TOPMed |
|
|
CA362893065 rs1390675159 |
15 | S>Y | No |
ClinGen gnomAD |
|
|
CA3683965 rs766745003 |
16 | T>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 17 | E>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3683966 rs754408387 |
18 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs1345590215 CA362893152 |
19 | Q>H | No |
ClinGen gnomAD |
|
|
rs755040937 CA3683967 |
22 | L>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 23 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 24 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA135849602 rs368236320 |
24 | V>D | No |
ClinGen ESP gnomAD |
|
|
CA362893231 rs1343788626 |
24 | V>I | No |
ClinGen TOPMed |
|
|
CA362893324 rs1158918211 |
28 | E>D | No |
ClinGen TOPMed |
|
|
CA362893355 rs1425809598 |
30 | E>K | No |
ClinGen TOPMed |
|
|
rs748292155 CA3683969 |
32 | A>D | No |
ClinGen ExAC gnomAD |
|
|
rs779131215 CA3683968 |
32 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA362893432 rs748292155 |
32 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA3683970 rs575160898 |
33 | G>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs575160898 CA362893449 |
33 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs575160898 CA3683971 |
33 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
VAR_028313 CA135849615 rs3857554 |
33 | G>V | No |
ClinGen UniProt Ensembl dbSNP |
|
|
rs3857555 VAR_028314 CA135849619 |
34 | F>L | No |
ClinGen UniProt Ensembl dbSNP |
|
|
rs769656345 CA3683973 |
35 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3683974 rs757265466 |
36 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs868347525 CA135849627 |
38 | P>S | No |
ClinGen Ensembl |
|
|
CA3683976 rs768652183 |
39 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3683975 rs199786583 |
39 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362893601 rs1160354899 |
40 | L>P | No |
ClinGen gnomAD |
|
|
rs1456901279 CA362893618 |
41 | G>R | No |
ClinGen gnomAD |
|
|
rs1259898237 CA362893698 |
44 | G>D | No |
ClinGen TOPMed |
|
|
CA362893730 rs1361361447 |
46 | R>C | No |
ClinGen TOPMed |
|
|
CA3683985 rs766769837 |
47 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362893754 rs766769837 |
47 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3683986 rs374346539 |
48 | R>C | No |
ClinGen ESP ExAC gnomAD |
|
|
CA362893799 rs1178931749 |
48 | R>P | No |
ClinGen gnomAD |
|
|
CA135849651 rs374346539 |
48 | R>S | No |
ClinGen ESP ExAC gnomAD |
|
|
CA362893825 rs1296454634 |
49 | F>Y | No |
ClinGen TOPMed |
|
|
CA362893849 rs1246641421 |
50 | R>* | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 50 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs367947574 CA135849657 |
50 | R>P | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs367947574 CA135849656 |
50 | R>Q | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs765890348 CA3683988 |
53 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1204550714 CA362893945 |
53 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
CA362893956 rs1249685169 |
54 | Y>C | No |
ClinGen gnomAD |
|
|
rs745404694 CA3683989 |
55 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1481766173 CA362893985 |
55 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3683991 rs777812007 |
56 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779824359 CA362894151 |
61 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 61 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs779824359 CA3683994 |
61 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768560195 CA3683996 |
63 | A>E | No |
ClinGen ExAC gnomAD |
|
|
rs768560195 COSM1233503 CA362894215 |
63 | A>V | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1301907313 CA362894221 |
64 | L>V | No |
ClinGen gnomAD |
|
|
rs1376434640 CA362894250 |
65 | S>G | No |
ClinGen gnomAD |
|
|
CA362894287 rs1352309480 |
66 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs771623673 CA3683999 |
66 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1341430212 CA362894338 |
68 | R>* | No |
ClinGen gnomAD |
|
|
rs1581733979 CA362894352 |
68 | R>P | No |
ClinGen Ensembl |
|
|
rs770547963 CA362894429 |
72 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs770547963 CA362894425 |
72 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA3684003 rs371849975 |
72 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs765796803 CA3684005 |
73 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs1185839472 CA362894559 |
76 | Q>E | No |
ClinGen gnomAD |
|
|
CA362894679 rs1449457620 |
79 | M>R | No |
ClinGen TOPMed gnomAD |
|
|
CA3684006 rs753276030 |
79 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA362894725 rs1187207114 |
80 | H>Q | No |
ClinGen gnomAD |
|
|
rs762886652 CA362894757 |
81 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746650166 CA135849696 |
83 | E>K | No |
ClinGen Ensembl |
|
|
rs200907251 CA3684009 |
84 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201695426 CA135849701 |
85 | I>F | No |
ClinGen TOPMed |
|
|
CA362895017 rs1581734141 |
90 | V>G | No |
ClinGen Ensembl |
|
|
rs965754720 CA135849705 |
90 | V>L | No |
ClinGen Ensembl |
|
|
CA3684011 rs757493017 |
92 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781443015 CA3684012 |
93 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA362895135 rs1397897878 |
94 | F>I | No |
ClinGen TOPMed |
|
|
rs1362493935 CA362895264 |
98 | L>Q | No |
ClinGen gnomAD |
|
|
rs778775387 CA3684015 |
99 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 100 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA362895344 rs1264203811 |
101 | N>S | No |
ClinGen gnomAD |
|
|
CA362895413 rs1464736968 |
103 | Q>* | No |
ClinGen gnomAD |
|
|
CA135849717 rs376377398 |
104 | S>N | No |
ClinGen ESP TOPMed |
|
| TCGA novel | 104 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs777323142 CA3684018 |
107 | R>Q | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 107 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA362895732 rs1309378590 |
113 | S>N | No |
ClinGen gnomAD |
|
|
CA362895750 rs1422406252 |
114 | G>R | No |
ClinGen gnomAD |
|
|
rs1422406252 CA362895758 |
114 | G>W | No |
ClinGen gnomAD |
|
|
CA362895823 rs1176694457 |
116 | E>A | No |
ClinGen gnomAD |
|
|
CA362895814 rs1481253171 |
116 | E>K | No |
ClinGen gnomAD |
|
|
rs770671984 CA3684020 |
117 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1455452037 CA362895878 |
118 | V>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3684021 rs147610271 |
119 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3684024 rs776074354 |
122 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA135849729 rs942337605 |
126 | R>T | No |
ClinGen TOPMed |
|
|
rs1225363768 CA362896202 |
128 | L>V | No |
ClinGen gnomAD |
|
|
rs1581734455 CA362896228 |
129 | D>G | No |
ClinGen Ensembl |
|
|
rs1244804692 CA362896272 |
130 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA3684025 COSM741625 rs199522744 |
131 | P>L | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA362896282 rs1284166375 |
131 | P>S | No |
ClinGen gnomAD |
|
|
CA3684027 rs751640380 |
132 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 136 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA135850043 rs201458242 |
136 | S>P | No |
ClinGen 1000Genomes |
|
|
CA362896598 rs1419667882 |
137 | G>V | No |
ClinGen TOPMed |
|
|
rs945415420 CA135850044 |
138 | V>F | No |
ClinGen TOPMed |
|
|
CA362896644 rs1180640603 |
140 | Q>P | No |
ClinGen TOPMed |
|
|
CA362896679 rs1257619120 |
141 | G>E | No |
ClinGen TOPMed |
|
|
CA362896674 rs1228998784 |
141 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA362896850 rs1201380045 |
147 | C>W | No |
ClinGen gnomAD |
|
|
CA3684069 rs760780379 |
148 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA3684071 rs766583821 |
150 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1430187099 CA362896960 |
153 | T>I | No |
ClinGen gnomAD |
|
|
CA362896968 rs1561938210 |
154 | P>Q | No |
ClinGen Ensembl |
|
|
CA362896967 rs1195483978 |
154 | P>S | No |
ClinGen gnomAD |
|
|
CA362896993 rs1264735076 |
156 | P>S | No |
ClinGen gnomAD |
|
|
CA3684074 rs112285963 |
157 | G>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA135850057 rs112285963 |
157 | G>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs879141552 CA135850062 |
160 | S>I | No |
ClinGen Ensembl |
|
|
CA3684076 rs757249339 |
164 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA3684077 rs767613445 |
165 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA135850070 rs941773043 |
165 | L>V | No |
ClinGen TOPMed |
|
|
CA3684079 rs200196282 |
167 | K>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1384386941 CA362897229 |
170 | L>F | No |
ClinGen gnomAD |
|
|
CA362897272 rs745445329 |
172 | H>L | No |
ClinGen TOPMed |
|
|
CA135850081 rs745445329 |
172 | H>P | No |
ClinGen TOPMed |
|
| TCGA novel | 172 | H>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA362897266 rs1329988085 |
172 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA3684082 rs755305286 |
176 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA362897339 rs1397471498 |
177 | S>T | No |
ClinGen TOPMed |
|
|
CA3684083 rs779130918 |
181 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1454226778 CA362897444 |
183 | R>S | No |
ClinGen TOPMed |
|
|
rs770113386 CA3684092 |
185 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs542397400 CA3684093 |
188 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs17856167 CA3684095 VAR_028315 |
189 | V>M | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA362898722 rs1457066539 |
192 | H>R | No |
ClinGen gnomAD |
|
| TCGA novel | 193 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM107379 CA135854422 rs150389758 |
196 | C>R | skin [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA3684099 rs760177769 |
199 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA3684097 rs750411773 |
199 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs760177769 CA3684098 |
199 | D>V | No |
ClinGen ExAC gnomAD |
|
|
VAR_059950 rs371085669 CA135854434 |
200 | K>A | requires 2 nucleotide substitutions [UniProt] | No |
ClinGen UniProt Ensembl dbSNP |
|
rs13201752 VAR_028316 CA3684100 |
200 | K>E | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1554147002 CA917704386 |
200 | K>S | No |
ClinGen Ensembl |
|
|
VAR_028317 rs13201753 CA3684101 |
200 | K>T | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1472994657 CA362898953 |
201 | V>A | No |
ClinGen TOPMed |
|
| TCGA novel | 201 | V>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753015829 CA3684104 |
203 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs752359473 CA3684121 |
212 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA362899363 rs1267520316 |
216 | V>M | No |
ClinGen gnomAD |
|
|
rs940769956 CA135854561 |
218 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
rs373340452 CA3684123 |
222 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757683465 CA135854570 |
224 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757683465 CA362899500 |
224 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757683465 CA3684125 |
224 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376383746 CA3684126 |
225 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1002086647 CA135854580 |
226 | E>A | No |
ClinGen Ensembl |
|
|
rs756244642 CA3684128 |
227 | W>G | No |
ClinGen ExAC gnomAD |
|
|
rs1270252190 CA362899592 |
228 | T>I | No |
ClinGen gnomAD |
|
|
CA362899602 rs1561939698 |
229 | Q>* | No |
ClinGen Ensembl |
|
|
CA3684130 rs780369343 |
230 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs749527890 CA3684131 |
231 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA362899692 rs1470132110 |
234 | Q>E | No |
ClinGen TOPMed gnomAD |
|
|
CA3684133 rs180861333 |
234 | Q>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3684134 rs199815062 COSM1077100 |
235 | G>E | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs1176716861 CA362899737 |
236 | N>I | No |
ClinGen TOPMed |
|
| TCGA novel | 237 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3684135 rs770729988 |
237 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs776649494 CA3684137 |
240 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1433827798 CA362899813 |
240 | D>H | No |
ClinGen TOPMed |
|
|
CA362899862 rs1364159305 |
243 | Q>* | No |
ClinGen gnomAD |
|
|
rs764731416 CA3684138 |
245 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs213227 VAR_028318 CA3684139 |
246 | H>Q | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA362899973 rs1401470623 |
250 | V>G | No |
ClinGen gnomAD |
|
|
rs1321630865 CA362899964 |
250 | V>L | No |
ClinGen gnomAD |
|
|
CA362899977 rs1225783225 |
251 | S>T | No |
ClinGen gnomAD |
|
|
rs762578877 CA362900002 |
253 | G>C | No |
ClinGen ExAC gnomAD |
|
|
CA3684140 rs762578877 |
253 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1408665124 CA362901322 |
254 | D>G | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 256 | K>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1223957194 CA362901390 |
260 | S>G | No |
ClinGen gnomAD |
|
|
rs763697463 CA3684158 |
261 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA3684159 rs376669131 |
262 | D>E | No |
ClinGen ESP ExAC |
|
|
CA135855085 rs868788171 |
264 | P>F | No |
ClinGen Ensembl |
|
|
rs767933328 CA3684161 |
264 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684160 rs762030177 |
264 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684163 rs756679493 |
265 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs149631927 CA3684162 |
265 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA362901453 rs1327165968 |
266 | A>P | No |
ClinGen TOPMed |
|
|
CA362901451 rs1327165968 |
266 | A>T | No |
ClinGen TOPMed |
|
|
rs1224077851 COSM3394035 CA362901462 |
266 | A>V | pancreas [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA362901467 rs1437734127 |
267 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA3684164 rs767030823 |
268 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767030823 CA362901479 |
268 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684165 rs753926921 |
270 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1234917554 CA362901582 |
273 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs530861047 CA3684167 |
273 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1475452431 CA362901610 |
275 | G>E | No |
ClinGen TOPMed |
|
|
rs550910872 CA3684168 |
277 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA135855108 rs956076768 |
278 | S>A | No |
ClinGen TOPMed gnomAD |
|
|
COSM1077101 CA3684170 rs758615120 |
278 | S>L | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA3684172 rs567539708 |
279 | C>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1289048414 CA362901678 |
279 | C>Y | No |
ClinGen TOPMed |
|
|
CA3684173 rs769689642 |
282 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 283 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3684174 rs780000077 |
283 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1181683828 CA362901743 |
284 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
CA362901752 rs1386955561 |
285 | I>V | No |
ClinGen gnomAD |
|
|
CA362901758 rs1473831158 |
286 | A>T | No |
ClinGen gnomAD |
|
|
rs1226312155 CA362901794 |
291 | C>Y | No |
ClinGen TOPMed |
|
|
rs1163872536 CA362901804 |
292 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 293 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs760813396 CA3684176 |
295 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1331361735 CA362901833 |
297 | Q>E | No |
ClinGen gnomAD |
|
|
rs368814264 CA135855123 |
297 | Q>R | No |
ClinGen ESP |
|
|
CA3684177 CA3684178 rs138948067 |
300 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA362901865 rs1385548012 |
302 | Q>* | No |
ClinGen gnomAD |
|
| TCGA novel | 307 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA135855129 rs986085569 |
308 | A>V | No |
ClinGen TOPMed |
|
|
rs771682676 CA3684179 |
309 | T>A | No |
ClinGen ExAC gnomAD |
|
|
COSM1077102 CA3684183 rs754406189 |
313 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA3684182 rs766941164 |
313 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA3684184 rs549317265 |
316 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3684185 rs765353601 |
316 | C>S | No |
ClinGen ExAC gnomAD |
|
|
CA3684186 rs752777641 |
317 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs777896212 CA3684188 |
318 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs777896212 CA362901971 |
318 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA362901974 rs1395252173 |
318 | E>V | No |
ClinGen TOPMed |
|
|
rs944168979 CA135855226 |
319 | C>R | No |
ClinGen TOPMed |
|
|
CA362901986 rs1372564290 |
320 | G>R | No |
ClinGen gnomAD |
|
|
CA362901994 rs1326810921 |
321 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs755927145 CA3684191 |
324 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684192 rs779909987 |
326 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 330 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3684194 rs372442268 |
332 | H>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1335090580 CA362902068 |
332 | H>Y | No |
ClinGen gnomAD |
|
|
CA135855238 rs894589483 |
333 | R>G | No |
ClinGen Ensembl |
|
|
CA3684195 rs778475648 |
333 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684196 rs747663992 |
333 | R>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 334 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771711866 CA3684197 |
336 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA362902104 rs1442680690 |
337 | T>I | No |
ClinGen gnomAD |
|
|
CA3684198 rs773019163 |
341 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1561941020 CA362902135 |
342 | Y>C | No |
ClinGen Ensembl |
|
|
rs201098027 CA3684200 |
343 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs201098027 CA135855254 |
343 | E>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs199841259 CA135855257 |
344 | C>R | No |
ClinGen 1000Genomes |
|
|
CA3684201 rs777201964 |
344 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA135855261 rs564531549 |
345 | E>K | No |
ClinGen gnomAD |
|
|
CA3684202 COSM3745108 rs376311714 |
346 | E>D | liver [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1236818559 CA362902174 |
348 | G>C | No |
ClinGen TOPMed |
|
|
CA135855266 rs1011662496 |
350 | A>G | No |
ClinGen TOPMed |
|
|
rs1011662496 CA135855269 |
350 | A>V | No |
ClinGen TOPMed |
|
|
CA3684203 rs571490028 |
351 | F>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3684204 rs537210927 |
352 | I>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs201837700 CA3684205 |
352 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3684207 rs573947578 |
357 | L>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA135855281 rs573947578 |
357 | L>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs369621239 CA3684208 |
360 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA362902270 rs1174780166 |
363 | V>L | No |
ClinGen gnomAD |
|
|
CA3684209 rs766162566 |
365 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684212 rs778759383 |
372 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA3684213 rs778759383 |
372 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs1298243575 CA362902367 |
376 | G>V | No |
ClinGen gnomAD |
|
|
CA135855300 rs867522523 |
378 | A>T | No |
ClinGen Ensembl |
|
|
rs777496466 CA3684215 |
378 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1331477315 CA362902400 |
381 | H>R | No |
ClinGen gnomAD |
|
|
rs746257891 CA3684219 |
386 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs903204324 CA135855313 |
387 | K>T | No |
ClinGen Ensembl |
|
|
CA3684220 rs760136180 |
389 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775883740 CA3684221 |
390 | R>G | No |
ClinGen ExAC |
|
|
CA3684222 rs763031450 |
390 | R>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA135855324 COSM1672302 rs868256061 |
391 | T>I | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA3684224 rs150709352 |
393 | T>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs762012780 CA3684225 |
393 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762012780 CA362902480 |
393 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3684226 rs762012780 |
393 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753603394 CA3684227 |
395 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs754748913 CA3684228 |
398 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1212363785 CA823632635 |
400 | C>* | No |
ClinGen TOPMed |
|
|
CA135855329 rs1019852969 |
401 | D>G | No |
ClinGen TOPMed |
|
|
rs765161018 CA3684229 |
401 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA3684230 rs61744865 |
405 | K>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3684232 rs758424457 |
406 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA362902867 rs1294936199 |
408 | S>R | No |
ClinGen gnomAD |
|
|
CA362902871 rs1353365249 |
408 | S>T | No |
ClinGen TOPMed |
|
|
CA362902884 rs1367807510 |
410 | S>C | No |
ClinGen gnomAD |
|
|
CA362902897 rs1304557318 |
411 | C>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1390634045 CA362902896 |
411 | C>F | No |
ClinGen gnomAD |
|
|
CA135855340 rs1031758556 |
414 | L>F | No |
ClinGen TOPMed |
|
|
CA362902932 rs1031758556 |
414 | L>V | No |
ClinGen TOPMed |
|
|
rs1379081996 CA362903043 |
419 | I>T | No |
ClinGen gnomAD |
|
|
rs746564908 CA3684234 |
421 | T>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1028495454 CA135855348 |
422 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA135855350 rs201791697 |
422 | G>V | No |
ClinGen 1000Genomes |
|
|
CA3684236 rs781022948 |
423 | E>K | No |
ClinGen ExAC |
|
|
rs956124366 CA135855355 |
425 | P>L | No |
ClinGen TOPMed |
|
|
rs952959025 CA135855363 |
428 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA362903280 rs1195638771 |
429 | S>G | No |
ClinGen gnomAD |
|
|
COSM294971 CA3684242 rs769212506 |
429 | S>N | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed |
|
rs572880509 CA135855367 |
430 | M>T | No |
ClinGen 1000Genomes TOPMed |
|
|
rs545072408 CA3684243 |
431 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3684245 COSM1567881 rs149951499 |
437 | R>* | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA362903615 rs1385093153 |
437 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA3684247 rs759303798 |
438 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs764933522 CA3684248 |
440 | H>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1311919 CA3684249 rs530750921 |
441 | L>F | urinary_tract [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs1471859344 CA362903831 |
444 | H>R | No |
ClinGen TOPMed |
|
|
CA135855394 rs200224676 |
445 | Q>R | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1266684085 CA362903975 |
447 | I>M | No |
ClinGen TOPMed |
|
|
CA3684251 rs147653277 |
447 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA362904011 rs751072693 |
448 | H>P | No |
ClinGen ExAC gnomAD |
|
|
CA3684252 rs751072693 |
448 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA135855406 rs983887016 |
449 | T>A | No |
ClinGen Ensembl |
|
|
CA362904062 rs1226722777 |
450 | G>E | No |
ClinGen gnomAD |
|
|
CA135855409 rs774000368 |
451 | D>A | No |
ClinGen gnomAD |
|
| TCGA novel | 451 | D>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA362904098 rs774000368 |
451 | D>V | No |
ClinGen gnomAD |
|
|
CA362904217 rs1581743695 |
453 | N>D | No |
ClinGen Ensembl |
|
| TCGA novel | 453 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3684254 rs780935220 |
454 | V>L | No |
ClinGen ExAC gnomAD |
|
|
COSM1270957 rs1336010967 CA362904363 |
456 | E>D | oesophagus [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA362904348 rs1249766515 |
456 | E>K | No |
ClinGen gnomAD |
|
|
rs1295665405 CA362904479 |
459 | Q>P | No |
ClinGen TOPMed |
|
|
rs750049250 CA3684255 |
460 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs1226100378 CA362904486 |
460 | G>R | No |
ClinGen TOPMed |
|
|
rs528701776 CA135855414 |
467 | M>V | No |
ClinGen Ensembl |
|
|
rs961057960 CA135855415 |
469 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
rs183665379 CA135855417 |
474 | V>G | No |
ClinGen 1000Genomes |
|
|
rs1427622470 CA362905408 |
484 | E>K | No |
ClinGen gnomAD |
|
|
rs1175410081 CA362905516 |
485 | C>* | No |
ClinGen TOPMed gnomAD |
|
|
rs140495719 CA3684259 |
485 | C>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1175410081 CA362905519 |
485 | C>W | No |
ClinGen TOPMed gnomAD |
|
|
CA3684260 rs561174912 |
485 | C>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs748164408 CA362905792 |
491 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs748164408 CA3684261 |
491 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA362905873 rs1450114435 |
493 | T>I | No |
ClinGen gnomAD |
|
|
CA362905892 rs1321422088 |
494 | G>S | No |
ClinGen Ensembl |
|
|
rs773405385 CA3684263 |
496 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA362906154 rs760791268 |
499 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA362906167 rs1454210638 |
500 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
CA362906165 rs1454210638 |
500 | K>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1320220338 CA362906204 |
501 | I>L | No |
ClinGen TOPMed gnomAD |
|
|
CA362906209 rs1320220338 |
501 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1219675612 CA362906283 |
502 | H>L | No |
ClinGen gnomAD |
|
|
CA135855429 rs865903418 |
503 | T>S | No |
ClinGen Ensembl |
|
|
rs1413220884 CA362906360 |
505 | E>K | No |
ClinGen TOPMed |
|
|
CA362906410 rs1187311674 |
506 | K>I | No |
ClinGen TOPMed |
|
|
rs771231647 CA3684265 |
511 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA362906687 rs1238486432 |
512 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
COSM1442826 rs1238486432 CA362906684 |
512 | A>V | Variant assessed as Somatic; 0.0 impact. liver large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs1561941844 CA362906708 |
513 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA135855436 rs991104256 |
515 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs764074093 CA3684269 |
516 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764074093 CA3684268 |
516 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762871156 CA3684267 |
516 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs1175516819 CA362906902 |
517 | F>C | No |
ClinGen gnomAD |
|
|
rs56184876 CA135855457 |
518 | T>A | No |
ClinGen TOPMed |
|
|
CA135855447 rs56184876 |
518 | T>P | No |
ClinGen TOPMed |
|
|
CA3684270 rs761340095 |
519 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs867295302 CA135855469 |
520 | I>S | No |
ClinGen Ensembl |
|
|
CA135855465 rs946512521 |
520 | I>V | No |
ClinGen Ensembl |
|
| TCGA novel | 521 | S>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1273036232 CA362907123 |
521 | S>P | No |
ClinGen TOPMed |
|
|
rs766933890 CA3684271 |
523 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA135855481 rs199753064 |
523 | L>R | No |
ClinGen 1000Genomes |
|
|
rs1561941924 CA362907265 |
525 | Q>* | No |
ClinGen Ensembl |
|
|
rs1296433872 CA362907301 |
526 | H>Y | No |
ClinGen TOPMed |
|
|
rs1453182897 CA362907359 |
527 | Q>E | No |
ClinGen gnomAD |
|
|
CA3684273 rs755702694 |
534 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs929084390 CA135855488 |
534 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs779798806 CA3684274 |
535 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs755362623 CA3684276 |
537 | S>L | No |
ClinGen ExAC gnomAD |
No associated diseases with Q9BRR0
9 regional properties for Q9BRR0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Krueppel-associated box | 214 - 274 | IPR001909 |
| domain | SCAN domain | 42 - 154 | IPR003309 |
| domain | Zinc finger C2H2-type | 314 - 341 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 342 - 369 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 370 - 397 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 398 - 425 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 426 - 453 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 480 - 507 | IPR013087-6 |
| domain | Zinc finger C2H2-type | 508 - 535 | IPR013087-7 |
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
8 GO annotations of molecular function
| Name | Definition |
|---|---|
| chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| DNA-binding transcription repressor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
| lysosome organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. |
| negative regulation of autophagy | Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. |
| negative regulation of cellular senescence | Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
177 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08DS3 | OSR1 | Protein odd-skipped-related 1 | Bos taurus (Bovine) | PR |
| Q2VWH6 | FEZF2 | Fez family zinc finger protein 2 | Bos taurus (Bovine) | PR |
| A6QNZ0 | ZSCAN26 | Zinc finger and SCAN domain-containing protein 26 | Bos taurus (Bovine) | PR |
| A7MBI1 | ZFP69 | Zinc finger protein 69 homolog | Bos taurus (Bovine) | PR |
| Q08705 | CTCF | Transcriptional repressor CTCF | Gallus gallus (Chicken) | PR |
| O42409 | GFI1B | Zinc finger protein Gfi-1b | Gallus gallus (Chicken) | PR |
| A2T6W2 | ZNF449 | Zinc finger protein 449 | Pan troglodytes (Chimpanzee) | PR |
| Q9U405 | grau | Transcription factor grauzone | Drosophila melanogaster (Fruit fly) | PR |
| Q7K0S9 | sug | Zinc finger protein GLIS2 homolog | Drosophila melanogaster (Fruit fly) | PR |
| P20385 | Cf2 | Chorion transcription factor Cf2 | Drosophila melanogaster (Fruit fly) | PR |
| Q86P48 | ATbp | AT-rich binding protein | Drosophila melanogaster (Fruit fly) | PR |
| P28698 | MZF1 | Myeloid zinc finger 1 | Homo sapiens (Human) | PR |
| Q9NTW7 | ZFP64 | Zinc finger protein 64 | Homo sapiens (Human) | PR |
| P08151 | GLI1 | Zinc finger protein GLI1 | Homo sapiens (Human) | PR |
| Q9UFB7 | ZBTB47 | Zinc finger and BTB domain-containing protein 47 | Homo sapiens (Human) | PR |
| P18146 | EGR1 | Early growth response protein 1 | Homo sapiens (Human) | PR |
| Q9Y5W3 | KLF2 | Krueppel-like factor 2 | Homo sapiens (Human) | PR |
| Q96SZ4 | ZSCAN10 | Zinc finger and SCAN domain-containing protein 10 | Homo sapiens (Human) | PR |
| P57682 | KLF3 | Krueppel-like factor 3 | Homo sapiens (Human) | PR |
| P25490 | YY1 | Transcriptional repressor protein YY1 | Homo sapiens (Human) | SS |
| O43296 | ZNF264 | Zinc finger protein 264 | Homo sapiens (Human) | PR |
| P49711 | CTCF | Transcriptional repressor CTCF | Homo sapiens (Human) | PR |
| Q9NQX1 | PRDM5 | PR domain zinc finger protein 5 | Homo sapiens (Human) | PR |
| Q9HBE1 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | Homo sapiens (Human) | PR |
| Q8TAX0 | OSR1 | Protein odd-skipped-related 1 | Homo sapiens (Human) | PR |
| Q8TBJ5 | FEZF2 | Fez family zinc finger protein 2 | Homo sapiens (Human) | PR |
| Q96SR6 | ZNF382 | Zinc finger protein 382 | Homo sapiens (Human) | PR |
| Q9ULJ3 | ZBTB21 | Zinc finger and BTB domain-containing protein 21 | Homo sapiens (Human) | PR |
| O75840 | KLF7 | Krueppel-like factor 7 | Homo sapiens (Human) | PR |
| Q13127 | REST | RE1-silencing transcription factor | Homo sapiens (Human) | PR |
| Q8IZM8 | ZNF654 | Zinc finger protein 654 | Homo sapiens (Human) | PR |
| Q14526 | HIC1 | Hypermethylated in cancer 1 protein | Homo sapiens (Human) | PR |
| Q06889 | EGR3 | Early growth response protein 3 | Homo sapiens (Human) | PR |
| Q08ER8 | ZNF543 | Zinc finger protein 543 | Homo sapiens (Human) | PR |
| Q8N680 | ZBTB2 | Zinc finger and BTB domain-containing protein 2 | Homo sapiens (Human) | PR |
| O95625 | ZBTB11 | Zinc finger and BTB domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q96BV0 | ZNF775 | Zinc finger protein 775 | Homo sapiens (Human) | PR |
| Q5FWF6 | ZNF789 | Zinc finger protein 789 | Homo sapiens (Human) | PR |
| Q05516 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | Homo sapiens (Human) | PR |
| Q9H116 | GZF1 | GDNF-inducible zinc finger protein 1 | Homo sapiens (Human) | PR |
| Q8IW36 | ZNF695 | Zinc finger protein 695 | Homo sapiens (Human) | PR |
| Q5VTD9 | GFI1B | Zinc finger protein Gfi-1b | Homo sapiens (Human) | PR |
| Q6PG37 | ZNF790 | Zinc finger protein 790 | Homo sapiens (Human) | PR |
| Q9NQV6 | PRDM10 | PR domain zinc finger protein 10 | Homo sapiens (Human) | PR |
| Q9Y2D9 | ZNF652 | Zinc finger protein 652 | Homo sapiens (Human) | PR |
| Q5TC79 | ZBTB37 | Zinc finger and BTB domain-containing protein 37 | Homo sapiens (Human) | PR |
| Q9Y4E5 | ZNF451 | E3 SUMO-protein ligase ZNF451 | Homo sapiens (Human) | PR |
| Q8ND82 | ZNF280C | Zinc finger protein 280C | Homo sapiens (Human) | PR |
| Q49AA0 | ZFP69 | Zinc finger protein 69 homolog | Homo sapiens (Human) | PR |
| O43298 | ZBTB43 | Zinc finger and BTB domain-containing protein 43 | Homo sapiens (Human) | PR |
| Q9Y330 | ZBTB12 | Zinc finger and BTB domain-containing protein 12 | Homo sapiens (Human) | PR |
| Q13105 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | Homo sapiens (Human) | PR |
| P51508 | ZNF81 | Zinc finger protein 81 | Homo sapiens (Human) | PR |
| Q5JNZ3 | ZNF311 | Zinc finger protein 311 | Homo sapiens (Human) | PR |
| Q9Y4X4 | KLF12 | Krueppel-like factor 12 | Homo sapiens (Human) | PR |
| P10074 | ZBTB48 | Telomere zinc finger-associated protein | Homo sapiens (Human) | PR |
| P17010 | ZFX | Zinc finger X-chromosomal protein | Homo sapiens (Human) | PR |
| Q9H5H4 | ZNF768 | Zinc finger protein 768 | Homo sapiens (Human) | PR |
| Q9Y2L8 | ZKSCAN5 | Zinc finger protein with KRAB and SCAN domains 5 | Homo sapiens (Human) | PR |
| Q86UZ6 | ZBTB46 | Zinc finger and BTB domain-containing protein 46 | Homo sapiens (Human) | PR |
| Q8NCP5 | ZBTB44 | Zinc finger and BTB domain-containing protein 44 | Homo sapiens (Human) | PR |
| P41182 | BCL6 | B-cell lymphoma 6 protein | Homo sapiens (Human) | PR |
| Q9NQX0 | PRDM6 | Putative histone-lysine N-methyltransferase PRDM6 | Homo sapiens (Human) | PR |
| Q9BU19 | ZNF692 | Zinc finger protein 692 | Homo sapiens (Human) | PR |
| Q08AG5 | ZNF844 | Zinc finger protein 844 | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| P98182 | ZNF200 | Zinc finger protein 200 | Homo sapiens (Human) | PR |
| Q9UK11 | ZNF223 | Zinc finger protein 223 | Homo sapiens (Human) | PR |
| O15156 | ZBTB7B | Zinc finger and BTB domain-containing protein 7B | Homo sapiens (Human) | PR |
| Q6ZMS7 | ZNF783 | Zinc finger protein 783 | Homo sapiens (Human) | PR |
| P59923 | ZNF445 | Zinc finger protein 445 | Homo sapiens (Human) | PR |
| Q8N859 | ZNF713 | Zinc finger protein 713 | Homo sapiens (Human) | PR |
| Q99612 | KLF6 | Krueppel-like factor 6 | Homo sapiens (Human) | PR |
| Q8TD17 | ZNF398 | Zinc finger protein 398 | Homo sapiens (Human) | PR |
| P52739 | ZNF131 | Zinc finger protein 131 | Homo sapiens (Human) | PR |
| Q05215 | EGR4 | Early growth response protein 4 | Homo sapiens (Human) | PR |
| Q7Z398 | ZNF550 | Zinc finger protein 550 | Homo sapiens (Human) | PR |
| Q9Y2K1 | ZBTB1 | Zinc finger and BTB domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q96N20 | ZNF75A | Zinc finger protein 75A | Homo sapiens (Human) | PR |
| A1YPR0 | ZBTB7C | Zinc finger and BTB domain-containing protein 7C | Homo sapiens (Human) | PR |
| P24278 | ZBTB25 | Zinc finger and BTB domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q96N38 | ZNF714 | Zinc finger protein 714 | Homo sapiens (Human) | PR |
| Q86YH2 | ZNF280B | Zinc finger protein 280B | Homo sapiens (Human) | PR |
| Q8NAM6 | ZSCAN4 | Zinc finger and SCAN domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q9NPC7 | MYNN | Myoneurin | Homo sapiens (Human) | PR |
| O14978 | ZNF263 | Zinc finger protein 263 | Homo sapiens (Human) | PR |
| P17022 | ZNF18 | Zinc finger protein 18 | Homo sapiens (Human) | PR |
| Q6P9G9 | ZNF449 | Zinc finger protein 449 | Homo sapiens (Human) | PR |
| O60304 | ZNF500 | Zinc finger protein 500 | Homo sapiens (Human) | PR |
| Q9NX65 | ZSCAN32 | Zinc finger and SCAN domain-containing protein 32 | Homo sapiens (Human) | PR |
| Q96IT1 | ZNF496 | Zinc finger protein 496 | Homo sapiens (Human) | PR |
| O14771 | ZNF213 | Zinc finger protein 213 | Homo sapiens (Human) | PR |
| O95125 | ZNF202 | Zinc finger protein 202 | Homo sapiens (Human) | PR |
| Q8IWY8 | ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 | Homo sapiens (Human) | PR |
| Q8N0Y2 | ZNF444 | Zinc finger protein 444 | Homo sapiens (Human) | PR |
| A6NGD5 | ZSCAN5C | Zinc finger and SCAN domain-containing protein 5C | Homo sapiens (Human) | PR |
| A6NJL1 | ZSCAN5B | Zinc finger and SCAN domain-containing protein 5B | Homo sapiens (Human) | PR |
| Q8NF99 | ZNF397 | Zinc finger protein 397 | Homo sapiens (Human) | PR |
| Q86XF7 | ZNF575 | Zinc finger protein 575 | Homo sapiens (Human) | PR |
| Q9NWS9 | ZNF446 | Zinc finger protein 446 | Homo sapiens (Human) | PR |
| Q96N95 | ZNF396 | Zinc finger protein 396 | Homo sapiens (Human) | PR |
| Q9UL58 | ZNF215 | Zinc finger protein 215 | Homo sapiens (Human) | PR |
| P17029 | ZKSCAN1 | Zinc finger protein with KRAB and SCAN domains 1 | Homo sapiens (Human) | PR |
| Q53GI3 | ZNF394 | Zinc finger protein 394 | Homo sapiens (Human) | PR |
| Q969J2 | ZKSCAN4 | Zinc finger protein with KRAB and SCAN domains 4 | Homo sapiens (Human) | PR |
| Q6NSZ9 | ZSCAN25 | Zinc finger and SCAN domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q9UNY5 | ZNF232 | Zinc finger protein 232 | Homo sapiens (Human) | PR |
| P17028 | ZNF24 | Zinc finger protein 24 | Homo sapiens (Human) | PR |
| Q63HK3 | ZKSCAN2 | Zinc finger protein with KRAB and SCAN domains 2 | Homo sapiens (Human) | PR |
| P49910 | ZNF165 | Zinc finger protein 165 | Homo sapiens (Human) | PR |
| Q15776 | ZKSCAN8 | Zinc finger protein with KRAB and SCAN domains 8 | Homo sapiens (Human) | PR |
| Q9H9D4 | ZNF408 | Zinc finger protein 408 | Homo sapiens (Human) | PR |
| O08584 | Klf6 | Krueppel-like factor 6 | Mus musculus (Mouse) | PR |
| Q61164 | Ctcf | Transcriptional repressor CTCF | Mus musculus (Mouse) | PR |
| Q810A1 | Znf18 | Zinc finger protein 18 | Mus musculus (Mouse) | PR |
| Q00899 | Yy1 | Transcriptional repressor protein YY1 | Mus musculus (Mouse) | PR |
| P41183 | Bcl6 | B-cell lymphoma 6 protein homolog | Mus musculus (Mouse) | PR |
| Q9DAI4 | Zbtb43 | Zinc finger and BTB domain-containing protein 43 | Mus musculus (Mouse) | PR |
| O70237 | Gfi1b | Zinc finger protein Gfi-1b | Mus musculus (Mouse) | PR |
| Q99KZ6 | Znf639 | Zinc finger protein 639 | Mus musculus (Mouse) | PR |
| Q9Z1D9 | Znf394 | Zinc finger protein 394 | Mus musculus (Mouse) | PR |
| Q9CXE0 | Prdm5 | PR domain zinc finger protein 5 | Mus musculus (Mouse) | PR |
| P43300 | Egr3 | Early growth response protein 3 | Mus musculus (Mouse) | PR |
| Q9DAU9 | Znf654 | Zinc finger protein 654 | Mus musculus (Mouse) | PR |
| Q9R1Y5 | Hic1 | Hypermethylated in cancer 1 protein | Mus musculus (Mouse) | PR |
| Q8R0T2 | Znf768 | Zinc finger protein 768 | Mus musculus (Mouse) | PR |
| Q9WVG7 | Osr1 | Protein odd-skipped-related 1 | Mus musculus (Mouse) | PR |
| Q8BI73 | Znf775 | Zinc finger protein 775 | Mus musculus (Mouse) | PR |
| Q8VCZ7 | Zbtb7c | Zinc finger and BTB domain-containing protein 7C | Mus musculus (Mouse) | PR |
| Q91VN1 | Znf24 | Zinc finger protein 24 | Mus musculus (Mouse) | PR |
| Q9DB38 | Znf580 | Zinc finger protein 580 | Mus musculus (Mouse) | PR |
| A7KBS4 | Zscan4d | Zinc finger and SCAN domain containing protein 4D | Mus musculus (Mouse) | PR |
| P10925 | Zfy1 | Zinc finger Y-chromosomal protein 1 | Mus musculus (Mouse) | PR |
| P08046 | Egr1 | Early growth response protein 1 | Mus musculus (Mouse) | PR |
| Q3TTC2 | Yy2 | Transcription factor YY2 | Mus musculus (Mouse) | PR |
| Q3UTQ7 | Prdm10 | PR domain zinc finger protein 10 | Mus musculus (Mouse) | PR |
| Q6P3Y5 | Znf280c | Zinc finger protein 280C | Mus musculus (Mouse) | PR |
| Q9ERU3 | Znf22 | Zinc finger protein 22 | Mus musculus (Mouse) | PR |
| Q8VIG1 | Rest | RE1-silencing transcription factor | Mus musculus (Mouse) | PR |
| Q9Z1D8 | Zkscan5 | Zinc finger protein with KRAB and SCAN domains 5 | Mus musculus (Mouse) | PR |
| Q8BID6 | Zbtb46 | Zinc finger and BTB domain-containing protein 46 | Mus musculus (Mouse) | PR |
| P17012 | Zfx | Zinc finger X-chromosomal protein | Mus musculus (Mouse) | PR |
| Q9WUK6 | Zbtb18 | Zinc finger and BTB domain-containing protein 18 | Mus musculus (Mouse) | PR |
| O35738 | Klf12 | Krueppel-like factor 12 | Mus musculus (Mouse) | PR |
| B2RXC5 | Znf382 | Zinc finger protein 382 | Mus musculus (Mouse) | PR |
| O08900 | Ikzf3 | Zinc finger protein Aiolos | Mus musculus (Mouse) | PR |
| Q5DU09 | Znf652 | Zinc finger protein 652 | Mus musculus (Mouse) | PR |
| Q5RJ54 | Zscan26 | Zinc finger and SCAN domain-containing protein 26 | Mus musculus (Mouse) | PR |
| Q8BLM0 | Klf8 | Krueppel-like factor 8 | Mus musculus (Mouse) | PR |
| Q99JB0 | Klf7 | Krueppel-like factor 7 | Mus musculus (Mouse) | PR |
| Q8R0A2 | Zbtb44 | Zinc finger and BTB domain-containing protein 44 | Mus musculus (Mouse) | PR |
| P20662 | Zfy2 | Zinc finger Y-chromosomal protein 2 | Mus musculus (Mouse) | PR |
| Q80VJ6 | Zscan4c | Zinc finger and SCAN domain containing protein 4C | Mus musculus (Mouse) | PR |
| Q3URS2 | Zscan4f | Zinc finger and SCAN domain containing protein 4F | Mus musculus (Mouse) | PR |
| Q60980 | Klf3 | Krueppel-like factor 3 | Mus musculus (Mouse) | PR |
| Q8K3J5 | Znf131 | Zinc finger protein 131 | Mus musculus (Mouse) | PR |
| Q8BGS3 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Mus musculus (Mouse) | PR |
| Q91VW9 | Zkscan3 | Zinc finger protein with KRAB and SCAN domains 3 | Mus musculus (Mouse) | PR |
| Q9Z2K3 | Znf394 | Zinc finger protein 394 | Rattus norvegicus (Rat) | PR |
| Q642B9 | Znf18 | Zinc finger protein 18 | Rattus norvegicus (Rat) | PR |
| B0K011 | Osr1 | Protein odd-skipped-related 1 | Rattus norvegicus (Rat) | PR |
| D3ZUU2 | Gzf1 | GDNF-inducible zinc finger protein 1 | Rattus norvegicus (Rat) | PR |
| B1WBU4 | Zbtb8a | Zinc finger and BTB domain-containing protein 8A | Rattus norvegicus (Rat) | PR |
| Q7TNK3 | Znf24 | Zinc finger protein 24 | Rattus norvegicus (Rat) | PR |
| O35819 | Klf6 | Krueppel-like factor 6 | Rattus norvegicus (Rat) | PR |
| Q9R1D1 | Ctcf | Transcriptional repressor CTCF | Rattus norvegicus (Rat) | PR |
| P43301 | Egr3 | Early growth response protein 3 | Rattus norvegicus (Rat) | PR |
| P08154 | Egr1 | Early growth response protein 1 | Rattus norvegicus (Rat) | PR |
| A0JPL0 | Znf382 | Zinc finger protein 382 | Rattus norvegicus (Rat) | PR |
| A1L1J6 | Znf652 | Zinc finger protein 652 | Rattus norvegicus (Rat) | PR |
| Q4KLI1 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Rattus norvegicus (Rat) | PR |
| Q9SHD0 | ZAT4 | Zinc finger protein ZAT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0P4X6 | zbtb44 | Zinc finger and BTB domain-containing protein 44 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4II20 | egr1 | Early growth response protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q6P882 | zbtb8a.2 | Zinc finger and BTB domain-containing protein 8A.2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q567C6 | znf367 | Zinc finger protein 367 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| A7Y7X5 | znf711 | Zinc finger protein 711 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARELSESTA | LDAQSTEDQM | ELLVIKVEEE | EAGFPSSPDL | GSEGSRERFR | GFRYPEAAGP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| REALSRLREL | CRQWLQPEMH | SKEQILELLV | LEQFLTILPG | NLQSWVREQH | PESGEEVVVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LEYLERQLDE | PAPQVSGVDQ | GQELLCCKMA | LLTPAPGSQS | SQFQLMKALL | KHESVGSQPL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QDRVLQVPVL | AHGGCCREDK | VVASRLTPES | QGLLKVEDVA | LTLTPEWTQQ | DSSQGNLCRD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EKQENHGSLV | SLGDEKQTKS | RDLPPAEELP | EKEHGKISCH | LREDIAQIPT | CAEAGEQEGR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LQRKQKNATG | GRRHICHECG | KSFAQSSGLS | KHRRIHTGEK | PYECEECGKA | FIGSSALVIH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QRVHTGEKPY | ECEECGKAFS | HSSDLIKHQR | THTGEKPYEC | DDCGKTFSQS | CSLLEHHRIH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TGEKPYQCSM | CGKAFRRSSH | LLRHQRIHTG | DKNVQEPEQG | EAWKSRMESQ | LENVETPMSY |
| 490 | 500 | 510 | 520 | 530 | |
| KCNECERSFT | QNTGLIEHQK | IHTGEKPYQC | NACGKGFTRI | SYLVQHQRSH | VGKNILSQ |