Q96300

PR
Gene name
GRF7 (At3g02520, F16B3.15)
Protein name
14-3-3-like protein GF14 nu
Names
General regulatory factor 7
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G02520
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

208-265 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q96300

Entry ID Method Resolution Chain Position Source
AF-Q96300-F1 Predicted AlphaFoldDB

18 variants for Q96300

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05758099 79 D>Y No 1000Genomes
tmp_3_527495_C_T 141 G>R No 1000Genomes
tmp_3_527473_G_A 148 A>V No 1000Genomes
ENSVATH05758098 154 A>T No 1000Genomes
ENSVATH05758093 168 P>S No 1000Genomes
tmp_3_527306_G_T 169 T>N No 1000Genomes
ENSVATH13859420 177 A>T No 1000Genomes
tmp_3_527235_G_T 193 R>S No 1000Genomes
tmp_3_527099_C_G 204 E>D No 1000Genomes
ENSVATH00302404 215 E>D No 1000Genomes
ENSVATH02105381 238 I>T No 1000Genomes
ENSVATH05758089 241 E>D No 1000Genomes
ENSVATH10458492 247 I>M No 1000Genomes
ENSVATH10458491 253 H>Y No 1000Genomes
ENSVATH02105370 254 E>K No 1000Genomes
ENSVATH05758088 257 E>D No 1000Genomes
tmp_3_526825_C_G 258 G>A No 1000Genomes
tmp_3_526822_T_A 259 K>I No 1000Genomes

No associated diseases with Q96300

3 regional properties for Q96300

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 45 - 55 IPR023409-1
conserved_site 14-3-3 protein, conserved site 217 - 236 IPR023409-2
domain 14-3-3 domain 5 - 248 IPR023410

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Translocates from the cytosol to the nucleus when phosphorylated
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein localization Any process in which a protein is transported to, or maintained in, a specific location.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

38 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q04917 YWHAH 14-3-3 protein eta Homo sapiens (Human) PR
P61981 YWHAG 14-3-3 protein gamma Homo sapiens (Human) PR
P31946 YWHAB 14-3-3 protein beta/alpha Homo sapiens (Human) PR
P27348 YWHAQ 14-3-3 protein theta Homo sapiens (Human) PR
P63104 YWHAZ 14-3-3 protein zeta/delta Homo sapiens (Human) PR
P49106 GRF1 14-3-3-like protein GF14-6 Zea mays (Maize) PR
Q01526 GRF2 14-3-3-like protein GF14-12 Zea mays (Maize) PR
P68510 Ywhah 14-3-3 protein eta Mus musculus (Mouse) PR
P63101 Ywhaz 14-3-3 protein zeta/delta Mus musculus (Mouse) PR
P93784 HOX 14-3-3-like protein 16R Solanum tuberosum (Potato) PR
Q41418 14-3-3-like protein Solanum tuberosum (Potato) PR
P63102 Ywhaz 14-3-3 protein zeta/delta Rattus norvegicus (Rat) PR
Q06967 GF14F 14-3-3-like protein GF14-F Oryza sativa subsp japonica (Rice) PR
Q2R2W2 GF14D 14-3-3-like protein GF14-D Oryza sativa subsp japonica (Rice) PR
Q6EUP4 GF14E 14-3-3-like protein GF14-E Oryza sativa subsp japonica (Rice) PR
Q6ZKC0 GF14C 14-3-3-like protein GF14-C Oryza sativa subsp japonica (Rice) PR
Q7XTE8 GF14B 14-3-3-like protein GF14-B Oryza sativa subsp japonica (Rice) PR
Q84J55 GF14A 14-3-3-like protein GF14-A Oryza sativa subsp japonica (Rice) PR
Q96452 GF14C 14-3-3-like protein C Glycine max (Soybean) (Glycine hispida) PR
Q96453 GF14D 14-3-3-like protein D Glycine max (Soybean) (Glycine hispida) PR
Q96450 GF14A 14-3-3-like protein A Glycine max (Soybean) (Glycine hispida) PR
P42645 GRF5 14-3-3-like protein GF14 upsilon Arabidopsis thaliana (Mouse-ear cress) PR
Q01525 GRF2 14-3-3-like protein GF14 omega Arabidopsis thaliana (Mouse-ear cress) PR
Q9C5W6 GRF12 14-3-3-like protein GF14 iota Arabidopsis thaliana (Mouse-ear cress) PR
P42644 GRF3 14-3-3-like protein GF14 psi Arabidopsis thaliana (Mouse-ear cress) PR
P46077 GRF4 14-3-3-like protein GF14 phi Arabidopsis thaliana (Mouse-ear cress) PR
Q96299 GRF9 14-3-3-like protein GF14 mu Arabidopsis thaliana (Mouse-ear cress) PR
Q9S9Z8 GRF11 14-3-3-like protein GF14 omicron Arabidopsis thaliana (Mouse-ear cress) PR
P42643 GRF1 14-3-3-like protein GF14 chi Arabidopsis thaliana (Mouse-ear cress) PR
P93212 TFT7 14-3-3 protein 7 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93209 TFT3 14-3-3 protein 3 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93207 TFT10 14-3-3 protein 10 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93214 TFT9 14-3-3 protein 9 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93211 TFT6 14-3-3 protein 6 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93206 TFT1 14-3-3 protein 1 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93213 TFT8 14-3-3 protein 8 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93208 TFT2 14-3-3 protein 2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P42652 TFT4 14-3-3 protein 4 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MSSSREENVY LAKLAEQAER YEEMVEFMEK VAKTVDTDEL TVEERNLLSV AYKNVIGARR
70 80 90 100 110 120
ASWRIISSIE QKEESRGNDD HVSIIKDYRG KIETELSKIC DGILNLLDSH LVPTASLAES
130 140 150 160 170 180
KVFYLKMKGD YHRYLAEFKT GAERKEAAES TLVAYKSAQD IALADLAPTH PIRLGLALNF
190 200 210 220 230 240
SVFYYEILNS PDRACSLAKQ AFDEAISELD TLGEESYKDS TLIMQLLRDN LTLWNSDIND
250 260
EAGGDEIKEA SKHEPEEGKP AETGQ