Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q948U0

Entry ID Method Resolution Chain Position Source
AF-Q948U0-F1 Predicted AlphaFoldDB

No variants for Q948U0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q948U0

No associated diseases with Q948U0

7 regional properties for Q948U0

Type Name Position InterPro Accession
domain EF-hand domain 240 - 311 IPR002048
domain FAD-binding 8 638 - 751 IPR013112
domain Ferric reductase, NAD binding domain 758 - 945 IPR013121
domain Ferric reductase transmembrane component-like domain 439 - 595 IPR013130
domain NADPH oxidase Respiratory burst 182 - 279 IPR013623
domain FAD-binding domain, ferredoxin reductase-type 634 - 754 IPR017927
binding_site EF-Hand 1, calcium-binding site 289 - 301 IPR018247

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).
ferric-chelate reductase activity Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor.
NAD(P)H oxidase H2O2-forming activity Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.
peroxidase activity Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

12 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96PH1 NOX5 NADPH oxidase 5 Homo sapiens (Human) EV
Q948T9 RBOHB Respiratory burst oxidase homolog protein B Solanum tuberosum (Potato) PR
Q2HXK9 RBOHD Respiratory burst oxidase homolog protein D Solanum tuberosum (Potato) PR
Q5ZAJ0 RBOHB Respiratory burst oxidase homolog protein B Oryza sativa subsp japonica (Rice) PR
P92949 CDC5 Ferric reduction oxidase 2 Arabidopsis thaliana (Mouse-ear cress) PR
O81211 RBOHE Respiratory burst oxidase homolog protein E Arabidopsis thaliana (Mouse-ear cress) PR
F4I4K7 FRO3 Ferric reduction oxidase 3, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8W110 FRO4 Ferric reduction oxidase 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FIJ0 RBOHD Respiratory burst oxidase homolog protein D Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJD6 RBOHH Putative respiratory burst oxidase homolog protein H Arabidopsis thaliana (Mouse-ear cress) PR
O48538 RBOHF Respiratory burst oxidase homolog protein F Arabidopsis thaliana (Mouse-ear cress) PR
Q9SUT8 RBOHI Probable respiratory burst oxidase homolog protein I Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MRGLPGHERR WTSDTVSSGK DLSGESSPGT DSGNISGFAS EEFVEVILDL QDDDTIILRS
70 80 90 100 110 120
VEPATVINID ASDPATGVGI GGVSIETPAS LTSTSGTRSP TMRRSTSNKL RQFSQELKAE
130 140 150 160 170 180
AVAKAKHFSQ ELKAELRRFS WSHGHASRTF SPASFFQNAV VGTGNGVDSA LAARALRRQR
190 200 210 220 230 240
AQLDRTRSSA HKALRGLKFI SNNKTNGWNE VENNFAKLAK DGYLYRSDFA QCIGMKDSKE
250 260 270 280 290 300
FALELFDALS RRRRLKVDKI SKEELYEYWS QITDQSFDSR LQIFFDMVDK NEDGRIGEEE
310 320 330 340 350 360
VKEIIMLSAS ANKLSRLKEQ AEEYAALIME ELDPERLGYI ELWQLETLLL QKDTYLNYSQ
370 380 390 400 410 420
ALSYTSQALS QNLQGLRKRS PIRRMSTKLV YSLQENWKRI WVLVLWILIM IGLFLWKFYL
430 440 450 460 470 480
YKQKSAFQVM GYCLLTAKGA AETLKFNMAL ILLPVCRNTI TFLRSTKLSC FVPFDDNINF
490 500 510 520 530 540
HKTVAAAIVT GIILHAGNHL VCDFPKLIHA NNTNYQKYLV NDFGPSQPQY IDLVKGVEGV
550 560 570 580 590 600
TGIIMVILMA IAFTLATRWF RRSLIKFPKP FDRLTGFNAF WYSHHLLIIV YIVLIIHGTF
610 620 630 640 650 660
LYLVHNWYSK TTWMYLAVPV LLYAGERTLR FFRSGLYTVR LLKVAIYPGN VLTLQMSKPP
670 680 690 700 710 720
QFRYKSGQYM FVQCPAVSPF EWHPFSITSA PGDDYLSIHI RQLGDWTQEL KRVFSEACEQ
730 740 750 760 770 780
PEAGKSGLLR ADENTKTSLP KLLIDGPYGA PAQDYRKYDV LLLVGLGIGA TPFISILKDL
790 800 810 820 830 840
LKNIVTMEEQ ADLVSDFSGN SDMSAATSEQ PALNKISPKK RKSTLKTTNA YFYWVTREQG
850 860 870 880 890 900
SFDWFKGVMN EVAELDQRGV IEMHNYLTSV YEEGDARSAL ITMVQALNHA KNGVDIVSGT
910 920 930 940 950 960
SVRTHFARPN WRKVFSKTLT KHANARIGVF YCGAPILAKE LSKLCKEFNQ KGTTKFEFHK
EHF