Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8TAX0

Entry ID Method Resolution Chain Position Source
AF-Q8TAX0-F1 Predicted AlphaFoldDB

195 variants for Q8TAX0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs1430444346
CA346227690
2 G>D No ClinGen
TOPMed
CA1542444
rs745601259
2 G>S No ClinGen
ExAC
TOPMed
gnomAD
CA346227674
rs1558359994
4 K>N No ClinGen
Ensembl
CA1542443
rs778633008
4 K>Q No ClinGen
ExAC
gnomAD
CA346227669
rs1162732154
5 T>S No ClinGen
TOPMed
CA346227657
rs1415409140
7 P>R No ClinGen
gnomAD
TCGA novel 7 P>missing Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs951855533
CA43713585
7 P>T No ClinGen
TOPMed
rs756917295
CA1542442
8 A>G No ClinGen
ExAC
gnomAD
rs1417749076
CA346227639
10 V>A No ClinGen
gnomAD
CA346227644
rs1158816346
10 V>M No ClinGen
gnomAD
rs748946826
CA1542441
13 H>Y No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 14 P>S Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs777186968
CA1542440
14 P>T No ClinGen
ExAC
gnomAD
rs1558359952
CA346227611
15 S>A No ClinGen
Ensembl
CA1542439
rs755578955
15 S>Y No ClinGen
ExAC
gnomAD
CA1542438
rs753222267
16 L>P No ClinGen
ExAC
TOPMed
gnomAD
CA346227605
rs753222267
16 L>R No ClinGen
ExAC
TOPMed
gnomAD
rs767950855
CA346227597
17 Q>H No ClinGen
ExAC
TOPMed
gnomAD
rs755336350
CA1542436
20 N>K No ClinGen
ExAC
TOPMed
gnomAD
CA346227569
rs1288940098
22 S>P No ClinGen
gnomAD
rs530028849
CA1542435
25 Q>P No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA346227521
rs1297384433
29 G>S No ClinGen
gnomAD
CA43713517
rs886665270
31 P>R No ClinGen
Ensembl
CA346227500
rs1436842858
33 V>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
CA1542433
rs763136719
34 P>A No ClinGen
ExAC
gnomAD
CA346227484
rs1323366899
35 S>L No ClinGen
gnomAD
rs1558359912
CA346227470
37 H>Q No ClinGen
Ensembl
rs765266778
CA1542431
37 H>R No ClinGen
ExAC
gnomAD
CA1542430
rs761936888
39 P>T No ClinGen
ExAC
TOPMed
gnomAD
CA1542429
rs775583465
40 N>S No ClinGen
ExAC
TOPMed
gnomAD
CA346227442
rs1176954593
42 Y>C No ClinGen
gnomAD
rs1262347464
CA346227436
43 G>D No ClinGen
TOPMed
gnomAD
CA43713500
rs370575190
43 G>S No ClinGen
ESP
TOPMed
gnomAD
TCGA novel 46 A>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs748922957
CA1542424
49 A>P No ClinGen
ExAC
gnomAD
rs748922957
CA346227395
COSM1530150
49 A>S lung [Cosmic] No ClinGen
cosmic curated
ExAC
gnomAD
CA346227396
rs748922957
49 A>T No ClinGen
ExAC
gnomAD
rs1315057016
CA346227389
50 V>L No ClinGen
gnomAD
rs1369403119
CA346227377
52 L>M No ClinGen
TOPMed
gnomAD
CA1542422
rs769304282
53 H>R No ClinGen
ExAC
gnomAD
rs747587694
CA1542421
55 W>R No ClinGen
ExAC
gnomAD
CA346227344
rs1388802506
56 T>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
CA346227345
rs1388802506
56 T>R No ClinGen
gnomAD
CA346227342
rs1455842063
57 L>V No ClinGen
gnomAD
CA1542419
rs755540358
58 G>D No ClinGen
ExAC
TOPMed
gnomAD
rs780326478
CA1542417
60 P>Q No ClinGen
ExAC
TOPMed
gnomAD
CA1542418
rs752087418
60 P>T No ClinGen
ExAC
gnomAD
TCGA novel 61 A>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1011740676
CA43713458
62 M>R No ClinGen
TOPMed
CA346227295
rs1321340122
64 L>W No ClinGen
gnomAD
rs375985128
CA1542415
65 P>L No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs372422320
CA1542413
66 R>H No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs372422320
CA1542414
66 R>L No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA43713449
rs898159433
67 S>A No ClinGen
TOPMed
TCGA novel 68 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs139101150
CA1542412
69 F>L No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs868677006
CA346227262
70 S>C No ClinGen
TOPMed
gnomAD
CA43713440
rs868677006
70 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
gnomAD
TCGA novel 72 V>G Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs759585249
CA1542410
72 V>M No ClinGen
ExAC
TOPMed
gnomAD
rs947794638
CA43713436
73 P>L No ClinGen
gnomAD
CA346227245
rs947794638
73 P>Q No ClinGen
gnomAD
rs774303008
CA1542409
73 P>S No ClinGen
ExAC
gnomAD
CA1542407
rs762748716
75 T>M No ClinGen
ExAC
TOPMed
gnomAD
rs907421037
CA43713404
76 V>M Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
CA1542405
rs769498692
78 S>N No ClinGen
ExAC
TOPMed
gnomAD
rs1269805691
CA346227209
79 L>F No ClinGen
TOPMed
CA1542403
rs199763633
82 A>E No ClinGen
ExAC
TOPMed
gnomAD
rs199763633
CA43713390
82 A>V No ClinGen
ExAC
TOPMed
gnomAD
CA1542402
rs148662449
83 R>C No ClinGen
ESP
ExAC
TOPMed
gnomAD
COSM1014239
rs370211451
CA1542401
83 R>H endometrium [Cosmic] No ClinGen
cosmic curated
ESP
ExAC
TOPMed
gnomAD
rs1483660555
CA346227178
84 F>L No ClinGen
TOPMed
CA43713386
rs140787234
87 P>S No ClinGen
ESP
TOPMed
CA1542399
rs758705032
88 A>V No ClinGen
ExAC
gnomAD
CA346227152
rs1572259960
89 F>L No ClinGen
Ensembl
rs1056276138
CA43713362
90 P>S No ClinGen
TOPMed
gnomAD
TCGA novel 91 W>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA1542398
rs750733636
92 F>L No ClinGen
ExAC
gnomAD
CA1542397
rs779415526
93 P>H No ClinGen
ExAC
TOPMed
gnomAD
CA346227121
rs779415526
93 P>L No ClinGen
ExAC
TOPMed
gnomAD
CA1542396
rs757601212
94 H>Q No ClinGen
ExAC
gnomAD
rs1183484671
COSM1218964
CA346227116
94 H>R large_intestine [Cosmic] No ClinGen
cosmic curated
TOPMed
rs1486608015
CA346227113
95 V>I No ClinGen
gnomAD
CA1542395
rs543452352
96 I>L No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA346227106
rs543452352
96 I>V No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA346227090
rs1558359786
98 P>R No ClinGen
Ensembl
CA1542394
rs764299282
98 P>S No ClinGen
ExAC
gnomAD
CA346227092
rs764299282
98 P>T No ClinGen
ExAC
gnomAD
rs1413066323
CA346227078
100 P>S No ClinGen
TOPMed
CA1542391
rs766269293
103 T>A No ClinGen
ExAC
gnomAD
CA346227054
rs1306424843
103 T>I No ClinGen
gnomAD
TCGA novel 104 A>P Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA346227048
rs1299184840
104 A>V No ClinGen
gnomAD
rs1397194102
CA346227034
107 S>G No ClinGen
gnomAD
CA346227030
rs1436087381
107 S>N No ClinGen
TOPMed
rs762792163
CA1542390
107 S>R No ClinGen
ExAC
TOPMed
gnomAD
rs1369348149
CA346227026
108 V>F No ClinGen
TOPMed
CA346227012
rs562873645
110 A>G No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA1542389
rs562873645
COSM2904689
110 A>V pancreas [Cosmic] No ClinGen
cosmic curated
1000Genomes
ExAC
TOPMed
gnomAD
CA1542388
rs764998863
112 K>N No ClinGen
ExAC
gnomAD
CA43713335
rs923800427
114 K>Q No ClinGen
gnomAD
CA1542386
rs776229107
116 R>H No ClinGen
ExAC
gnomAD
rs768179728
CA1542385
121 N>K No ClinGen
ExAC
rs867715743
CA43713331
121 N>S Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
Ensembl
NCI-TCGA
CA43713321
rs769404421
124 L>W No ClinGen
Ensembl
TCGA novel 126 A>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA346226906
rs1476174107
127 T>M No ClinGen
gnomAD
TCGA novel 128 Q>H Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA346226903
rs1187082054
128 Q>K No ClinGen
gnomAD
CA1542380
rs779460509
128 Q>R No ClinGen
ExAC
gnomAD
rs1252331658
CA346226895
129 E>Q No ClinGen
gnomAD
rs1193773342
CA346226877
131 P>R No ClinGen
gnomAD
rs1191341346
CA346226873
132 A>T No ClinGen
gnomAD
rs975152724
CA43713311
135 G>C Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
gnomAD
CA43713310
rs1018830654
135 G>D Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
rs975152724
CA346226853
135 G>R No ClinGen
TOPMed
gnomAD
rs374867477
CA1542376
136 R>C Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
TOPMed
gnomAD
rs374867477
CA1542377
136 R>G No ClinGen
ExAC
TOPMed
gnomAD
CA346226847
rs1369401129
136 R>L No ClinGen
TOPMed
CA346226846
rs767477557
CA1542374
137 G>R No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 138 E>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 139 G>C Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA1542371
rs765050076
139 G>V No ClinGen
ExAC
gnomAD
TCGA novel 140 P>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1463104651
CA346226819
141 G>D No ClinGen
gnomAD
CA346226821
rs1294289762
141 G>R No ClinGen
gnomAD
CA346226822
rs1294289762
141 G>S No ClinGen
gnomAD
CA1542367
rs760240477
142 S>C No ClinGen
ExAC
TOPMed
gnomAD
CA1542368
rs760240477
142 S>F No ClinGen
ExAC
TOPMed
gnomAD
rs1164141110
CA346226802
144 A>E No ClinGen
gnomAD
CA1542366
rs775124127
145 G>D No ClinGen
ExAC
gnomAD
rs1179360144
CA346226793
146 G>E No ClinGen
gnomAD
rs771451659
CA1542365
146 G>R No ClinGen
ExAC
gnomAD
TCGA novel 146 G>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1267644701
CA346226783
148 G>C No ClinGen
gnomAD
CA43713256
rs893197225
148 G>D No ClinGen
TOPMed
gnomAD
rs1267644701
CA346226785
148 G>S No ClinGen
gnomAD
CA1542363
rs149742000
149 A>D No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA346226776
rs149742000
149 A>V No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1263865115
CA346226767
151 L>F No ClinGen
TOPMed
gnomAD
rs1271925561
CA346226761
152 D>G No ClinGen
gnomAD
CA1542362
rs771434319
152 D>N Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
CA346226752
rs1572259744
153 V>G No ClinGen
Ensembl
CA1542360
rs376388576
153 V>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
rs142934357
CA346226745
155 K>E No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs142934357
CA1542359
155 K>Q No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA43713237
rs147259951
157 S>P No ClinGen
ESP
TCGA novel 159 E>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA1542358
rs574615795
159 E>G No ClinGen
ExAC
gnomAD
CA346226714
rs1221411052
160 K>E No ClinGen
TOPMed
CA346226708
rs1247687590
160 K>N No ClinGen
TOPMed
CA43713226
rs781377076
161 K>N No ClinGen
ExAC
TOPMed
gnomAD
CA43713221
rs963629347
162 P>L No ClinGen
TOPMed
CA1542355
rs754976969
162 P>S No ClinGen
ExAC
gnomAD
COSM1014238
rs1457744690
CA346226674
166 R>H Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
NCI-TCGA
gnomAD
CA346226664
rs1156697377
168 P>S No ClinGen
gnomAD
TCGA novel 170 K>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 173 K>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 180 C>Y Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1404730075
CA346226565
181 G>D No ClinGen
TOPMed
CA346226554
rs1165317852
183 H>R No ClinGen
TOPMed
TCGA novel 184 F>L Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs752250481
CA1542348
190 L>R No ClinGen
ExAC
TOPMed
gnomAD
CA1542347
rs767076399
192 I>N No ClinGen
ExAC
gnomAD
TCGA novel 193 H>Y Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA1542344
rs771630452
199 D>E No ClinGen
ExAC
gnomAD
CA346226448
rs1236849681
199 D>H No ClinGen
TOPMed
gnomAD
rs1236849681
CA346226447
199 D>N Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
gnomAD
rs1328234056
CA346226410
204 T>I No ClinGen
gnomAD
rs1402723981
CA346226390
207 I>T No ClinGen
gnomAD
CA1542340
rs748437826
207 I>V No ClinGen
ExAC
TOPMed
gnomAD
CA346226374
rs1337476179
209 H>L No ClinGen
TOPMed
rs866968142
CA43713160
213 R>Q No ClinGen
Ensembl
TCGA novel 216 D>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA346226196
rs1193066952
232 K>N No ClinGen
TOPMed
gnomAD
rs1231313639
CA346226172
235 E>D No ClinGen
TOPMed
gnomAD
rs1572259235
CA346226163
236 C>W No ClinGen
Ensembl
TCGA novel 241 C>I Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 243 S>C Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs138448676
CA1542313
243 S>F No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1257733324
CA346226117
243 S>P No ClinGen
TOPMed
gnomAD
CA346226105
rs1572259211
245 T>P No ClinGen
Ensembl
CA346226098
rs1279917154
246 L>F No ClinGen
TOPMed
gnomAD
CA346226063
rs1196801661
251 T>M No ClinGen
TOPMed
gnomAD
CA1542309
rs766022107
254 S>T No ClinGen
ExAC
gnomAD
CA346226034
rs1558359236
256 V>M No ClinGen
Ensembl
rs765599206
CA346226016
258 E>D No ClinGen
ExAC
gnomAD
CA1542307
rs149037267
258 E>G No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs34404071
CA346226020
258 E>K No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA1542308
rs34404071
258 E>Q No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
TCGA novel 260 K>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA43712502
rs555776548
264 I>F No ClinGen
gnomAD
rs1558359218
CA346225964
266 C>R No ClinGen
Ensembl
CA346225957
rs1365155354
267 C>Q No ClinGen
Ensembl

No associated diseases with Q8TAX0

3 regional properties for Q8TAX0

Type Name Position InterPro Accession
domain Protein kinase domain 20 - 281 IPR000719
active_site Serine/threonine-protein kinase, active site 138 - 150 IPR008271
binding_site Protein kinase, ATP binding site 26 - 49 IPR017441

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extrinsic component of membrane The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding Binding to a metal ion.
RNA polymerase II transcription regulatory region sequence-specific DNA binding Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
sequence-specific double-stranded DNA binding Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.

51 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.
cellular response to retinoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
embryonic digit morphogenesis The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
embryonic forelimb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
embryonic hindlimb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
embryonic skeletal joint development The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
embryonic skeletal joint morphogenesis The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.
embryonic skeletal limb joint morphogenesis The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.
gonad development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
heart development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
intermediate mesoderm development The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.
mesangial cell development The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.
mesonephric duct morphogenesis The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.
mesonephros development The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.
metanephric cap mesenchymal cell proliferation involved in metanephros development The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
metanephric epithelium development The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
metanephric glomerulus vasculature development The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.
metanephric interstitial fibroblast development The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.
metanephric mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
metanephric mesenchyme development The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
metanephric mesenchyme morphogenesis The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
metanephric nephron tubule development The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
metanephric smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.
middle ear morphogenesis The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
negative regulation of creatine transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity.
negative regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.
negative regulation of nephron tubule epithelial cell differentiation Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.
negative regulation of sodium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.
negative regulation of transcription by RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
odontogenesis The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
pattern specification involved in metanephros development Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.
positive regulation of bone mineralization Any process that activates or increases the frequency, rate or extent of bone mineralization.
positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation.
positive regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation.
positive regulation of gene expression Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
posterior mesonephric tubule development The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.
pronephros development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
renal vesicle progenitor cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.
roof of mouth development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
sodium ion transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
specification of anterior mesonephric tubule identity The process in which the tubules of the anterior mesonephros acquire their identity.
specification of posterior mesonephric tubule identity The process in which the tubules of the posterior mesonephros acquire their identity.
stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
ureter urothelium development The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.
ureteric bud development The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
urogenital system development The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.

177 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2VWH6 FEZF2 Fez family zinc finger protein 2 Bos taurus (Bovine) PR
A6QNZ0 ZSCAN26 Zinc finger and SCAN domain-containing protein 26 Bos taurus (Bovine) PR
A7MBI1 ZFP69 Zinc finger protein 69 homolog Bos taurus (Bovine) PR
Q08DS3 OSR1 Protein odd-skipped-related 1 Bos taurus (Bovine) PR
Q08705 CTCF Transcriptional repressor CTCF Gallus gallus (Chicken) PR
O42409 GFI1B Zinc finger protein Gfi-1b Gallus gallus (Chicken) PR
A2T6W2 ZNF449 Zinc finger protein 449 Pan troglodytes (Chimpanzee) PR
Q9U405 grau Transcription factor grauzone Drosophila melanogaster (Fruit fly) PR
Q7K0S9 sug Zinc finger protein GLIS2 homolog Drosophila melanogaster (Fruit fly) PR
P20385 Cf2 Chorion transcription factor Cf2 Drosophila melanogaster (Fruit fly) PR
Q86P48 ATbp AT-rich binding protein Drosophila melanogaster (Fruit fly) PR
P28698 MZF1 Myeloid zinc finger 1 Homo sapiens (Human) PR
Q9NTW7 ZFP64 Zinc finger protein 64 Homo sapiens (Human) PR
O14978 ZNF263 Zinc finger protein 263 Homo sapiens (Human) PR
O60304 ZNF500 Zinc finger protein 500 Homo sapiens (Human) PR
P08151 GLI1 Zinc finger protein GLI1 Homo sapiens (Human) PR
Q9UFB7 ZBTB47 Zinc finger and BTB domain-containing protein 47 Homo sapiens (Human) PR
P18146 EGR1 Early growth response protein 1 Homo sapiens (Human) PR
Q9Y5W3 KLF2 Krueppel-like factor 2 Homo sapiens (Human) PR
Q9UNY5 ZNF232 Zinc finger protein 232 Homo sapiens (Human) PR
Q96SZ4 ZSCAN10 Zinc finger and SCAN domain-containing protein 10 Homo sapiens (Human) PR
P17028 ZNF24 Zinc finger protein 24 Homo sapiens (Human) PR
P57682 KLF3 Krueppel-like factor 3 Homo sapiens (Human) PR
P25490 YY1 Transcriptional repressor protein YY1 Homo sapiens (Human) SS
O43296 ZNF264 Zinc finger protein 264 Homo sapiens (Human) PR
P49711 CTCF Transcriptional repressor CTCF Homo sapiens (Human) PR
Q9NQX1 PRDM5 PR domain zinc finger protein 5 Homo sapiens (Human) PR
Q9HBE1 PATZ1 POZ-, AT hook-, and zinc finger-containing protein 1 Homo sapiens (Human) PR
Q9UL58 ZNF215 Zinc finger protein 215 Homo sapiens (Human) PR
Q8TBJ5 FEZF2 Fez family zinc finger protein 2 Homo sapiens (Human) PR
Q96SR6 ZNF382 Zinc finger protein 382 Homo sapiens (Human) PR
Q96IT1 ZNF496 Zinc finger protein 496 Homo sapiens (Human) PR
Q96N95 ZNF396 Zinc finger protein 396 Homo sapiens (Human) PR
Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 Homo sapiens (Human) PR
O75840 KLF7 Krueppel-like factor 7 Homo sapiens (Human) PR
Q9H9D4 ZNF408 Zinc finger protein 408 Homo sapiens (Human) PR
Q13127 REST RE1-silencing transcription factor Homo sapiens (Human) PR
Q8IZM8 ZNF654 Zinc finger protein 654 Homo sapiens (Human) PR
Q14526 HIC1 Hypermethylated in cancer 1 protein Homo sapiens (Human) PR
P17022 ZNF18 Zinc finger protein 18 Homo sapiens (Human) PR
Q86XF7 ZNF575 Zinc finger protein 575 Homo sapiens (Human) PR
Q06889 EGR3 Early growth response protein 3 Homo sapiens (Human) PR
Q8NAM6 ZSCAN4 Zinc finger and SCAN domain-containing protein 4 Homo sapiens (Human) PR
Q08ER8 ZNF543 Zinc finger protein 543 Homo sapiens (Human) PR
P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 Homo sapiens (Human) PR
Q8N680 ZBTB2 Zinc finger and BTB domain-containing protein 2 Homo sapiens (Human) PR
O95625 ZBTB11 Zinc finger and BTB domain-containing protein 11 Homo sapiens (Human) PR
Q9NPC7 MYNN Myoneurin Homo sapiens (Human) PR
Q96BV0 ZNF775 Zinc finger protein 775 Homo sapiens (Human) PR
Q8NF99 ZNF397 Zinc finger protein 397 Homo sapiens (Human) PR
Q63HK3 ZKSCAN2 Zinc finger protein with KRAB and SCAN domains 2 Homo sapiens (Human) PR
Q5FWF6 ZNF789 Zinc finger protein 789 Homo sapiens (Human) PR
Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 Homo sapiens (Human) PR
Q53GI3 ZNF394 Zinc finger protein 394 Homo sapiens (Human) PR
O95125 ZNF202 Zinc finger protein 202 Homo sapiens (Human) PR
Q05516 ZBTB16 Zinc finger and BTB domain-containing protein 16 Homo sapiens (Human) PR
Q9H116 GZF1 GDNF-inducible zinc finger protein 1 Homo sapiens (Human) PR
Q8N0Y2 ZNF444 Zinc finger protein 444 Homo sapiens (Human) PR
Q6P9G9 ZNF449 Zinc finger protein 449 Homo sapiens (Human) PR
Q8IW36 ZNF695 Zinc finger protein 695 Homo sapiens (Human) PR
Q5VTD9 GFI1B Zinc finger protein Gfi-1b Homo sapiens (Human) PR
Q6PG37 ZNF790 Zinc finger protein 790 Homo sapiens (Human) PR
Q9NQV6 PRDM10 PR domain zinc finger protein 10 Homo sapiens (Human) PR
Q9Y2D9 ZNF652 Zinc finger protein 652 Homo sapiens (Human) PR
Q5TC79 ZBTB37 Zinc finger and BTB domain-containing protein 37 Homo sapiens (Human) PR
Q9Y4E5 ZNF451 E3 SUMO-protein ligase ZNF451 Homo sapiens (Human) PR
Q8ND82 ZNF280C Zinc finger protein 280C Homo sapiens (Human) PR
Q49AA0 ZFP69 Zinc finger protein 69 homolog Homo sapiens (Human) PR
O43298 ZBTB43 Zinc finger and BTB domain-containing protein 43 Homo sapiens (Human) PR
Q9Y330 ZBTB12 Zinc finger and BTB domain-containing protein 12 Homo sapiens (Human) PR
Q13105 ZBTB17 Zinc finger and BTB domain-containing protein 17 Homo sapiens (Human) PR
P51508 ZNF81 Zinc finger protein 81 Homo sapiens (Human) PR
Q5JNZ3 ZNF311 Zinc finger protein 311 Homo sapiens (Human) PR
Q9BRR0 ZKSCAN3 Zinc finger protein with KRAB and SCAN domains 3 Homo sapiens (Human) PR
Q969J2 ZKSCAN4 Zinc finger protein with KRAB and SCAN domains 4 Homo sapiens (Human) PR
P49910 ZNF165 Zinc finger protein 165 Homo sapiens (Human) PR
Q9Y4X4 KLF12 Krueppel-like factor 12 Homo sapiens (Human) PR
P10074 ZBTB48 Telomere zinc finger-associated protein Homo sapiens (Human) PR
P17010 ZFX Zinc finger X-chromosomal protein Homo sapiens (Human) PR
Q9H5H4 ZNF768 Zinc finger protein 768 Homo sapiens (Human) PR
Q6NSZ9 ZSCAN25 Zinc finger and SCAN domain-containing protein 25 Homo sapiens (Human) PR
Q9Y2L8 ZKSCAN5 Zinc finger protein with KRAB and SCAN domains 5 Homo sapiens (Human) PR
Q86UZ6 ZBTB46 Zinc finger and BTB domain-containing protein 46 Homo sapiens (Human) PR
Q9NX65 ZSCAN32 Zinc finger and SCAN domain-containing protein 32 Homo sapiens (Human) PR
O14771 ZNF213 Zinc finger protein 213 Homo sapiens (Human) PR
Q8IWY8 ZSCAN29 Zinc finger and SCAN domain-containing protein 29 Homo sapiens (Human) PR
Q8NCP5 ZBTB44 Zinc finger and BTB domain-containing protein 44 Homo sapiens (Human) PR
P41182 BCL6 B-cell lymphoma 6 protein Homo sapiens (Human) PR
Q9NQX0 PRDM6 Putative histone-lysine N-methyltransferase PRDM6 Homo sapiens (Human) PR
Q9BU19 ZNF692 Zinc finger protein 692 Homo sapiens (Human) PR
Q08AG5 ZNF844 Zinc finger protein 844 Homo sapiens (Human) PR
Q6R2W3 ZBED9 SCAN domain-containing protein 3 Homo sapiens (Human) PR
P98182 ZNF200 Zinc finger protein 200 Homo sapiens (Human) PR
Q9UK11 ZNF223 Zinc finger protein 223 Homo sapiens (Human) PR
O15156 ZBTB7B Zinc finger and BTB domain-containing protein 7B Homo sapiens (Human) PR
Q6ZMS7 ZNF783 Zinc finger protein 783 Homo sapiens (Human) PR
P59923 ZNF445 Zinc finger protein 445 Homo sapiens (Human) PR
Q8N859 ZNF713 Zinc finger protein 713 Homo sapiens (Human) PR
Q99612 KLF6 Krueppel-like factor 6 Homo sapiens (Human) PR
Q8TD17 ZNF398 Zinc finger protein 398 Homo sapiens (Human) PR
P52739 ZNF131 Zinc finger protein 131 Homo sapiens (Human) PR
A6NGD5 ZSCAN5C Zinc finger and SCAN domain-containing protein 5C Homo sapiens (Human) PR
Q05215 EGR4 Early growth response protein 4 Homo sapiens (Human) PR
Q7Z398 ZNF550 Zinc finger protein 550 Homo sapiens (Human) PR
Q9Y2K1 ZBTB1 Zinc finger and BTB domain-containing protein 1 Homo sapiens (Human) PR
Q96N20 ZNF75A Zinc finger protein 75A Homo sapiens (Human) PR
A6NJL1 ZSCAN5B Zinc finger and SCAN domain-containing protein 5B Homo sapiens (Human) PR
A1YPR0 ZBTB7C Zinc finger and BTB domain-containing protein 7C Homo sapiens (Human) PR
Q9NWS9 ZNF446 Zinc finger protein 446 Homo sapiens (Human) PR
P24278 ZBTB25 Zinc finger and BTB domain-containing protein 25 Homo sapiens (Human) PR
Q96N38 ZNF714 Zinc finger protein 714 Homo sapiens (Human) PR
Q86YH2 ZNF280B Zinc finger protein 280B Homo sapiens (Human) PR
O08584 Klf6 Krueppel-like factor 6 Mus musculus (Mouse) PR
Q61164 Ctcf Transcriptional repressor CTCF Mus musculus (Mouse) PR
Q810A1 Znf18 Zinc finger protein 18 Mus musculus (Mouse) PR
Q8BGS3 Zkscan1 Zinc finger protein with KRAB and SCAN domains 1 Mus musculus (Mouse) PR
Q00899 Yy1 Transcriptional repressor protein YY1 Mus musculus (Mouse) PR
P41183 Bcl6 B-cell lymphoma 6 protein homolog Mus musculus (Mouse) PR
Q9DAI4 Zbtb43 Zinc finger and BTB domain-containing protein 43 Mus musculus (Mouse) PR
O70237 Gfi1b Zinc finger protein Gfi-1b Mus musculus (Mouse) PR
Q99KZ6 Znf639 Zinc finger protein 639 Mus musculus (Mouse) PR
Q9Z1D9 Znf394 Zinc finger protein 394 Mus musculus (Mouse) PR
Q9CXE0 Prdm5 PR domain zinc finger protein 5 Mus musculus (Mouse) PR
P43300 Egr3 Early growth response protein 3 Mus musculus (Mouse) PR
Q9DAU9 Znf654 Zinc finger protein 654 Mus musculus (Mouse) PR
Q9R1Y5 Hic1 Hypermethylated in cancer 1 protein Mus musculus (Mouse) PR
Q8R0T2 Znf768 Zinc finger protein 768 Mus musculus (Mouse) PR
Q8BI73 Znf775 Zinc finger protein 775 Mus musculus (Mouse) PR
Q8VCZ7 Zbtb7c Zinc finger and BTB domain-containing protein 7C Mus musculus (Mouse) PR
Q91VN1 Znf24 Zinc finger protein 24 Mus musculus (Mouse) PR
Q9DB38 Znf580 Zinc finger protein 580 Mus musculus (Mouse) PR
A7KBS4 Zscan4d Zinc finger and SCAN domain containing protein 4D Mus musculus (Mouse) PR
Q91VW9 Zkscan3 Zinc finger protein with KRAB and SCAN domains 3 Mus musculus (Mouse) PR
P10925 Zfy1 Zinc finger Y-chromosomal protein 1 Mus musculus (Mouse) PR
P08046 Egr1 Early growth response protein 1 Mus musculus (Mouse) PR
Q3TTC2 Yy2 Transcription factor YY2 Mus musculus (Mouse) PR
Q3UTQ7 Prdm10 PR domain zinc finger protein 10 Mus musculus (Mouse) PR
Q6P3Y5 Znf280c Zinc finger protein 280C Mus musculus (Mouse) PR
Q9ERU3 Znf22 Zinc finger protein 22 Mus musculus (Mouse) PR
Q8VIG1 Rest RE1-silencing transcription factor Mus musculus (Mouse) PR
Q9Z1D8 Zkscan5 Zinc finger protein with KRAB and SCAN domains 5 Mus musculus (Mouse) PR
Q8BID6 Zbtb46 Zinc finger and BTB domain-containing protein 46 Mus musculus (Mouse) PR
P17012 Zfx Zinc finger X-chromosomal protein Mus musculus (Mouse) PR
Q9WUK6 Zbtb18 Zinc finger and BTB domain-containing protein 18 Mus musculus (Mouse) PR
O35738 Klf12 Krueppel-like factor 12 Mus musculus (Mouse) PR
B2RXC5 Znf382 Zinc finger protein 382 Mus musculus (Mouse) PR
O08900 Ikzf3 Zinc finger protein Aiolos Mus musculus (Mouse) PR
Q5DU09 Znf652 Zinc finger protein 652 Mus musculus (Mouse) PR
Q5RJ54 Zscan26 Zinc finger and SCAN domain-containing protein 26 Mus musculus (Mouse) PR
Q8BLM0 Klf8 Krueppel-like factor 8 Mus musculus (Mouse) PR
Q99JB0 Klf7 Krueppel-like factor 7 Mus musculus (Mouse) PR
Q8R0A2 Zbtb44 Zinc finger and BTB domain-containing protein 44 Mus musculus (Mouse) PR
P20662 Zfy2 Zinc finger Y-chromosomal protein 2 Mus musculus (Mouse) PR
Q80VJ6 Zscan4c Zinc finger and SCAN domain containing protein 4C Mus musculus (Mouse) PR
Q3URS2 Zscan4f Zinc finger and SCAN domain containing protein 4F Mus musculus (Mouse) PR
Q60980 Klf3 Krueppel-like factor 3 Mus musculus (Mouse) PR
Q8K3J5 Znf131 Zinc finger protein 131 Mus musculus (Mouse) PR
Q9WVG7 Osr1 Protein odd-skipped-related 1 Mus musculus (Mouse) PR
Q9Z2K3 Znf394 Zinc finger protein 394 Rattus norvegicus (Rat) PR
Q642B9 Znf18 Zinc finger protein 18 Rattus norvegicus (Rat) PR
D3ZUU2 Gzf1 GDNF-inducible zinc finger protein 1 Rattus norvegicus (Rat) PR
B1WBU4 Zbtb8a Zinc finger and BTB domain-containing protein 8A Rattus norvegicus (Rat) PR
Q7TNK3 Znf24 Zinc finger protein 24 Rattus norvegicus (Rat) PR
O35819 Klf6 Krueppel-like factor 6 Rattus norvegicus (Rat) PR
Q9R1D1 Ctcf Transcriptional repressor CTCF Rattus norvegicus (Rat) PR
P43301 Egr3 Early growth response protein 3 Rattus norvegicus (Rat) PR
P08154 Egr1 Early growth response protein 1 Rattus norvegicus (Rat) PR
A0JPL0 Znf382 Zinc finger protein 382 Rattus norvegicus (Rat) PR
Q4KLI1 Zkscan1 Zinc finger protein with KRAB and SCAN domains 1 Rattus norvegicus (Rat) PR
A1L1J6 Znf652 Zinc finger protein 652 Rattus norvegicus (Rat) PR
B0K011 Osr1 Protein odd-skipped-related 1 Rattus norvegicus (Rat) PR
Q9SHD0 ZAT4 Zinc finger protein ZAT4 Arabidopsis thaliana (Mouse-ear cress) PR
Q0P4X6 zbtb44 Zinc finger and BTB domain-containing protein 44 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
A4II20 egr1 Early growth response protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q6P882 zbtb8a.2 Zinc finger and BTB domain-containing protein 8A.2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q567C6 znf367 Zinc finger protein 367 Danio rerio (Zebrafish) (Brachydanio rerio) PR
A7Y7X5 znf711 Zinc finger protein 711 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MGSKTLPAPV PIHPSLQLTN YSFLQAVNGL PTVPSDHLPN LYGFSALHAV HLHQWTLGYP
70 80 90 100 110 120
AMHLPRSSFS KVPGTVSSLV DARFQLPAFP WFPHVIQPKP EITAGGSVPA LKTKPRFDFA
130 140 150 160 170 180
NLALAATQED PAKLGRGEGP GSPAGGLGAL LDVTKLSPEK KPTRGRLPSK TKKEFVCKFC
190 200 210 220 230 240
GRHFTKSYNL LIHERTHTDE RPYTCDICHK AFRRQDHLRD HRYIHSKEKP FKCQECGKGF
250 260
CQSRTLAVHK TLHSQVKELK TSKIKC