Q8RXX9
Gene name |
ATL6 (At3g05200, T12H1.17) |
Protein name |
E3 ubiquitin-protein ligase ATL6 |
Names |
RING-H2 finger protein ATL6, RING-type E3 ubiquitin transferase ATL6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G05200 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8RXX9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8RXX9-F1 | Predicted | AlphaFoldDB |
21 variants for Q8RXX9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05774509 | 20 | I>L | No | 1000Genomes | |
| tmp_3_1477602_G_A | 76 | V>I | No | 1000Genomes | |
| ENSVATH10501060 | 85 | G>V | No | 1000Genomes | |
| tmp_3_1477848_G_A | 158 | A>T | No | 1000Genomes | |
| tmp_3_1477932_G_A | 186 | G>R | No | 1000Genomes | |
| tmp_3_1477944_C_T | 190 | P>S | No | 1000Genomes | |
| ENSVATH05774513 | 198 | V>M | No | 1000Genomes | |
| tmp_3_1477992_A_G | 206 | T>A | No | 1000Genomes | |
| ENSVATH05774515 | 217 | E>D | No | 1000Genomes | |
| tmp_3_1478031_G_C | 219 | D>H | No | 1000Genomes | |
| tmp_3_1478041_G_A | 222 | R>K | No | 1000Genomes | |
| ENSVATH10501062 | 263 | V>L | No | 1000Genomes | |
| tmp_3_1478196_A_C | 274 | N>H | No | 1000Genomes | |
| ENSVATH13872208 | 316 | S>T | No | 1000Genomes | |
| ENSVATH05774516 | 333 | S>T | No | 1000Genomes | |
| ENSVATH10501063 | 344 | V>I | No | 1000Genomes | |
| ENSVATH05774517 | 368 | P>S | No | 1000Genomes | |
| ENSVATH10501064 | 373 | N>S | No | 1000Genomes | |
| ENSVATH00306953 | 387 | S>N | No | 1000Genomes | |
| tmp_3_1478550_G_A | 392 | G>S | No | 1000Genomes | |
| ENSVATH10501105 | 394 | V>G | No | 1000Genomes |
No associated diseases with Q8RXX9
1 regional properties for Q8RXX9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, RING-type | 127 - 170 | IPR001841 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| ubiquitin-protein transferase activity | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to bacterium | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
| defense response to other organism | Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRSSDHMAFA | GVLPIVFLLI | LSSADLAASQ | SQPGPTNQPY | NYGRLSPAMA | VIVVILIAAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FFMGFFSIYF | RHCSGVPDAG | VSPAGGARSR | ATVNAAARGL | DVSVVETFPT | FLYSDVKTQK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LGKGELECAI | CLNEFEDDET | LRLLPKCDHV | FHPHCIDAWL | EAHVTCPVCR | ANLAEQVAEG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ESVEPGGTEP | DLELQQVVVN | PEPVVTAPVP | EQLVTSEVDS | RRLPGVPVDL | KRVKFSRSHT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TGHSVVQPGE | CTERFTLRLP | EDVRKRIMKD | WKLNRTNSLL | VLPRGGSSRR | GKPIDRSRAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDRWLFRKTP | SFLWRSRDDG | SIRLGATGSV | RASAVPNSTG | SDSVRAGDRW | AFLRNASFLW |
| 370 | 380 | 390 | |||
| RNSSVHVPRG | GVNKDGEGTS | VKSTGASGST | SGSVRLPV |