Q8R2N0
Gene name |
Ccdc59 (D10Ertd718e, Tap26) |
Protein name |
Thyroid transcription factor 1-associated protein 26 |
Names |
TTF-1-associated protein 26, Coiled-coil domain-containing protein 59 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:52713 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8R2N0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8R2N0-F1 | Predicted | AlphaFoldDB |
15 variants for Q8R2N0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs581810484 | 6 | P>R | No | EVA | |
| rs257117099 | 7 | S>T | No | EVA | |
| rs242063935 | 9 | K>R | No | EVA | |
| rs249565925 | 18 | R>H | No | EVA | |
| rs211782822 | 22 | I>T | No | EVA | |
| rs584222548 | 51 | K>E | No | EVA | |
| rs3389125742 | 67 | Y>* | No | EVA | |
| rs3389123138 | 78 | P>L | No | EVA | |
| rs30523007 | 79 | A>E | No | EVA | |
| rs237953941 | 105 | R>S | No | EVA | |
| rs255963339 | 122 | R>Q | No | EVA | |
| rs226535659 | 134 | T>I | No | EVA | |
| rs30523009 | 139 | P>Q | No | EVA | |
| rs215638175 | 143 | H>N | No | EVA | |
| rs3389126309 | 174 | E>D | No | EVA |
No associated diseases with Q8R2N0
No regional properties for Q8R2N0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8R2N0 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O75113 | N4BP1 | NEDD4-binding protein 1 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPSRPSSKW | RTGGFAARGE | GISQVRFGNQ | NGKRRTWRPN | PQQAFRGSVR | KGQGFAFRRK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKIQQNYKKL | LWKVKEAPAS | QESQFTDRYP | EHLKHLYLAE | EERLRKQQRK | AGLALSEEQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DRPLPEEEGS | TEQTSSEEPP | GGHQPQPEEL | NTGSSVTFPK | NKKKKTSNQK | AQEEYERVQA |
| 190 | 200 | 210 | 220 | 230 | |
| KRAAKKFEFE | MRKQEREEAQ | RLYKKKKMEA | FKILSKKTKK | GQPNLNLQME | YLLQKIQENS |