Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8MIB7

Entry ID Method Resolution Chain Position Source
AF-Q8MIB7-F1 Predicted AlphaFoldDB

No variants for Q8MIB7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8MIB7

No associated diseases with Q8MIB7

2 regional properties for Q8MIB7

Type Name Position InterPro Accession
domain Homeobox domain 48 - 115 IPR001356
domain Homeobox KN domain 68 - 107 IPR008422

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O00470 MEIS1 Homeobox protein Meis1 Homo sapiens (Human) SS
O14770 MEIS2 Homeobox protein Meis2 Homo sapiens (Human) EV
Q8IUE0 TGIF2LY Homeobox protein TGIF2LY Homo sapiens (Human) PR
Q8IUE1 TGIF2LX Homeobox protein TGIF2LX Homo sapiens (Human) PR
P97368 Meis3 Homeobox protein Meis3 Mus musculus (Mouse) PR
P97367 Meis2 Homeobox protein Meis2 Mus musculus (Mouse) SS
Q75LX7 OSH10 Homeobox protein knotted-1-like 4 Oryza sativa subsp japonica (Rice) PR
Q75LX9 Os03g0673500 Putative homeobox protein knotted-1-like 5 Oryza sativa subsp japonica (Rice) PR
Q1PFD1 BLH11 BEL1-like homeodomain protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIW1 BLH7 BEL1-like homeodomain protein 7 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEAAADGPAE TQSPVQKDSP AKTQSPAQDT SIMSRNNADT GRVLALPEHK KKRKGNLPAE
70 80 90 100 110 120
SVKILRDWMY KHRFKAYPSE EEKQMLSEKT NLSLLQISNW FINARRRILP DMLQQHRNDP
130 140 150 160 170 180
IIGHKTGKDA HATHLQSTEA SVPAKSGPSG PDNVQSLPLW PLPKGQMSRE KQPDPESAPS
190 200 210 220 230 240
QKLTGIAQPK KKVKVSITSP SSPELVSPEE YADFSSFLLL VDAAVQRAAE LELEKKQEPN
P