Q8LGA5

PR
Gene name
ATL31 (CNI1, SSV1, At5g27420, F21A20.130)
Protein name
E3 ubiquitin-protein ligase ATL31
Names
Protein CARBON/NITROGEN INSENSITIVE 1, Protein SUPER SURVIVAL 1, RING-H2 finger protein ATL31, RING-type E3 ubiquitin transferase ATL31
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G27420
EC number
2.3.2.27: Aminoacyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

49-134 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8LGA5

Entry ID Method Resolution Chain Position Source
AF-Q8LGA5-F1 Predicted AlphaFoldDB

45 variants for Q8LGA5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_9684167_C_A 17 L>I No 1000Genomes
tmp_5_9684168_T_A 17 L>Q No 1000Genomes
ENSVATH07064658 26 G>E No 1000Genomes
ENSVATH14249990 75 G>R No 1000Genomes
ENSVATH14249991 81 G>E No 1000Genomes
tmp_5_9684363_G_T 82 G>V No 1000Genomes
ENSVATH14249992 90 A>T No 1000Genomes
ENSVATH07064659 94 R>C No 1000Genomes
ENSVATH11155679 98 A>V No 1000Genomes
ENSVATH07064665 178 V>M No 1000Genomes
tmp_5_9684653_G_T 179 V>L No 1000Genomes
ENSVATH09589020 180 V>A No 1000Genomes
ENSVATH09589019 180 V>M No 1000Genomes
ENSVATH03143680 181 E>V No 1000Genomes
tmp_5_9684663_C_T 182 T>I No 1000Genomes
ENSVATH11155682 186 A>G No 1000Genomes
ENSVATH11155681 186 A>T No 1000Genomes
ENSVATH00654265 191 A>T No 1000Genomes
tmp_5_9684696_C_A 193 P>H No 1000Genomes
ENSVATH03143682 194 V>E No 1000Genomes
ENSVATH00654266 202 V>I No 1000Genomes
tmp_5_9684775_G_T 219 E>D No 1000Genomes
ENSVATH03143683 254 G>E No 1000Genomes
ENSVATH03143684 255 G>R No 1000Genomes
ENSVATH11155735 289 G>D No 1000Genomes
tmp_5_9685008_G_T 297 G>V No 1000Genomes
ENSVATH03143691 298 S>N No 1000Genomes
ENSVATH00654268 308 S>T No 1000Genomes
tmp_5_9685062_A_G 315 D>G No 1000Genomes
tmp_5_9685085_C_T 323 P>S No 1000Genomes
tmp_5_9685097_T_C 327 W>R No 1000Genomes
ENSVATH00654269 329 N>T No 1000Genomes
ENSVATH14249993 330 T>M No 1000Genomes
tmp_5_9685113_C_T 332 P>L No 1000Genomes
ENSVATH07064670 332 P>S No 1000Genomes
ENSVATH07064671 334 P>L No 1000Genomes
ENSVATH00654270 339 E>G No 1000Genomes
tmp_5_9685172_C_G 352 Q>E No 1000Genomes
ENSVATH07064672 356 T>I No 1000Genomes
ENSVATH00654273 357 V>A No 1000Genomes
ENSVATH03143693 360 T>A No 1000Genomes
ENSVATH14249994 363 S>F No 1000Genomes
ENSVATH03143695 364 L>V No 1000Genomes
tmp_5_9685218_C_T 367 P>L No 1000Genomes
tmp_5_9685221_T_C 368 V>A No 1000Genomes

No associated diseases with Q8LGA5

1 regional properties for Q8LGA5

Type Name Position InterPro Accession
domain Zinc finger, RING-type 123 - 166 IPR001841

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
ubiquitin-protein transferase activity Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.

5 GO annotations of biological process

Name Definition
cellular response to hypoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
cellular response to nitrogen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
defense response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
response to abscisic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VE61 CG7694 E3 ubiquitin-protein ligase RNF181 homolog Drosophila melanogaster (Fruit fly) PR
O00237 RNF103 E3 ubiquitin-protein ligase RNF103 Homo sapiens (Human) PR
Q86Y13 DZIP3 E3 ubiquitin-protein ligase DZIP3 Homo sapiens (Human) PR
Q9Y3E7 CHMP3 Charged multivesicular body protein 3 Homo sapiens (Human) EV
Q9R1W3 Rnf103 E3 ubiquitin-protein ligase RNF103 Mus musculus (Mouse) PR
Q9EPZ8 Rnf103 E3 ubiquitin-protein ligase RNF103 Rattus norvegicus (Rat) PR
Q9ZV51 ATL56 RING-H2 finger protein ATL56 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SKK8 ATL22 RING-H2 finger protein ATL22 Arabidopsis thaliana (Mouse-ear cress) PR
P0CH02 ATL21B Putative RING-H2 finger protein ATL21B Arabidopsis thaliana (Mouse-ear cress) PR
P0CH01 ATL21A Putative RING-H2 finger protein ATL21A Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXF8 SGR9 E3 ubiquitin-protein ligase SGR9, amyloplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUZ9 ATL63 RING-H2 finger protein ATL63 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI09 XERICO Probable E3 ubiquitin-protein ligase XERICO Arabidopsis thaliana (Mouse-ear cress) PR
O22255 ATL64 RING-H2 finger protein ATL64 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYT9 SIS3 E3 ubiquitin-protein ligase SIS3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RXX9 ATL6 E3 ubiquitin-protein ligase ATL6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZJ6 ATL5 RING-H2 finger protein ATL5 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDPIKHISLP VLVLFLLLSV SAGQPGTPDQ RHDPYAYSGS LSPAMAVVVV VVIAALFFMG
70 80 90 100 110 120
FFTVYIRHCT GAVDGSVTPA GGARRRVTNA TVARGLDAET IETFPTFVYS EVKTQKIGKG
130 140 150 160 170 180
ALECAICLNE FEDDETLRLL PKCDHVFHPH CIGAWLQGHV TCPVCRTNLA EQTPEPEVVV
190 200 210 220 230 240
ETDLEAQQQS AVPVPVVELP RVKFPRSHTT GHSVVLPGES TDRFTLRVPE ELRKKIMANW
250 260 270 280 290 300
KLNRSNSVFV LPRGGSSRSG KQVDRSRAKS DRWLFRKTPS FLWRNRDDGS IRLGGTGSVR
310 320 330 340 350 360
GNSVTSPSGD SVRADRWAFL RNPSFLWRNT TPVPSPRVEV NNKDGEGTSS VQHIGTVGST
SGSLRLPV