Q8GXF8
PR
Gene name |
SGR9 (At5g02750, F9G14.60) |
Protein name |
E3 ubiquitin-protein ligase SGR9, amyloplastic |
Names |
Protein SHOOT GRAVITROPISM 9, RING-type E3 ubiquitin transferase SGR9 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G02750 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8GXF8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8GXF8-F1 | Predicted | AlphaFoldDB |
32 variants for Q8GXF8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_620106_A_C | 2 | E>D | No | 1000Genomes | |
| ENSVATH06910894 | 2 | E>G | No | 1000Genomes | |
| ENSVATH06910895 | 4 | E>G | No | 1000Genomes | |
| tmp_5_620132_C_T | 11 | A>V | No | 1000Genomes | |
| tmp_5_620134_T_A | 12 | S>T | No | 1000Genomes | |
| ENSVATH10511687 | 20 | H>Q | No | 1000Genomes | |
| ENSVATH03010897 | 26 | H>R | No | 1000Genomes | |
| tmp_5_620264_A_T | 55 | H>L | No | 1000Genomes | |
| tmp_5_620275_C_T,G | 59 | L>V | No | 1000Genomes | |
| tmp_5_620279_C_T | 60 | S>F | No | 1000Genomes | |
| ENSVATH00602537 | 67 | L>V | No | 1000Genomes | |
| tmp_5_620341_A_C | 81 | I>L | No | 1000Genomes | |
| tmp_5_620480_A_G | 127 | E>G | No | 1000Genomes | |
| ENSVATH13887927 | 134 | S>F | No | 1000Genomes | |
| ENSVATH06910897 | 137 | M>I | No | 1000Genomes | |
| ENSVATH03010898 | 156 | I>L | No | 1000Genomes | |
| tmp_5_620692_G_A | 198 | A>T | No | 1000Genomes | |
| ENSVATH10511691 | 201 | V>A | No | 1000Genomes | |
| ENSVATH06910900 | 207 | S>L | No | 1000Genomes | |
| ENSVATH03010899 | 209 | A>S | No | 1000Genomes | |
| ENSVATH00602538 | 235 | F>L | No | 1000Genomes | |
| tmp_5_620894_C_T | 265 | S>L | No | 1000Genomes | |
| tmp_5_620893_T_A | 265 | S>T | No | 1000Genomes | |
| ENSVATH03010900 | 270 | L>F | No | 1000Genomes | |
| tmp_5_620924_T_C | 275 | V>A | No | 1000Genomes | |
| tmp_5_620923_G_C | 275 | V>L | No | 1000Genomes | |
| ENSVATH13887934 | 277 | S>C | No | 1000Genomes | |
| tmp_5_620932_A_T | 278 | S>C | No | 1000Genomes | |
| tmp_5_620933_G_A | 278 | S>N | No | 1000Genomes | |
| ENSVATH06910903 | 278 | S>R | No | 1000Genomes | |
| ENSVATH03010901 | 280 | L>I | No | 1000Genomes | |
| ENSVATH13887955 | 283 | A>T | No | 1000Genomes |
No associated diseases with Q8GXF8
1 regional properties for Q8GXF8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, RING-type | 213 - 255 | IPR001841 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| amyloplast | A plastid whose main function is to synthesize and store starch. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. |
| ubiquitin-protein transferase activity | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| gravitropism | The orientation of plant parts under the stimulation of gravity. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEDENTTIIM | ASLSALSPSH | LTNLTHSILS | ISHHHRRRLG | AVLSSPTLFS | LTLRHLLSLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPDKTHLIAN | HLLSLLHPLL | IHRKHHSSYA | VTMKLRDLDA | VVLLLFLCET | HQLHPDVLEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SADNWREILG | NTYSNNMLSN | NSGLWTCDAG | ILMPYIETLV | RCKRFVDIMG | GYNHLRRRDQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEGYQVPAAR | AAVVALRAVE | VFNVAASNAG | EVECVICKEE | MSEGRDVCEM | PCQHFFHWKC |
| 250 | 260 | 270 | 280 | ||
| ILPWLSKKNT | CPFCRFQLPT | DDVFSEIQRL | WEILVKSSEL | HVA |